Barry R Oâ Keefe (Barry R O'Keefe)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 72

Top Topics

Breast Cancer Cells

Top Venues

Journal of natural products

Molecules (Basel, Switzerland)

Nature communications

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Taylor B Smallwood, Lauren R H Krumpe, Colton D Payne, Victoria G Klein, Barry R Oâ Keefe, Richard J Clark, Christina I Schroeder, K Johan Rosengren
Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analogues. Chemical science 15 (33) (2024)
Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Unusual Vilasinin-Class Limonoids from Trichilia rubescens . Molecules (Basel, Switzerland) 29 (3) (2024)
Dongdong Wang, Wei Jiang, Mehal Churiwal, Katrina Jia, Sarath P D Senadeera, Heidi R Bokesch, Girma M Woldemichael, Yong Kim, Robert G Hawley, Jun S Wei, Javed Khan, Barry R Oâ Keefe, John A A Beutler, Kirk R Gustafson
Neopetrotaurines A-C, Isoquinoline Alkaloids with an Unprecedented Taurine Bridge from the Sponge Neopetrosia sp. Journal of natural products 87 (2) (2024)
Dongdong Wang, Wei Jiang, Mehal Churiwal, Katrina Jia, Sarath P D Senadeera, Heidi R Bokesch, Girma M Woldemichael, Yong Kim, Robert G Hawley, Jun S Wei, Javed Khan, Barry R Oâ Keefe, John A A Beutler, Kirk R Gustafson
Neopetrotaurines A-C, Isoquinoline Alkaloids with an Unprecedented Taurine Bridge from the Sponge Neopetrosia sp. Journal of natural products 87 (2) (2024)
Ayano Kobayashi, Yohei Saito, Katsunori Miyake, Shuichi Fukuyoshi, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora . Journal of natural products 87 (2) (2024)
Maria Orfanoudaki, Rhone K Akee, Lucero Martínez-Fructuoso, Dongdong Wang, James A Kelley, Emily A Smith, Curtis J Henrich, Martin J Schnermann, Barry R Oâ Keefe, Tanja Grkovic
Formation of Trideuteromethylated Artifacts of Pyrrole-Containing Natural Products. Journal of natural products 87 (2) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Unusual Vilasinin-Class Limonoids from Trichilia rubescens . Molecules (Basel, Switzerland) 29 (3) (2024)
Dongdong Wang, Wei Jiang, Mehal Churiwal, Katrina Jia, Sarath P D Senadeera, Heidi R Bokesch, Girma M Woldemichael, Yong Kim, Robert G Hawley, Jun S Wei, Javed Khan, Barry R Oâ Keefe, John A A Beutler, Kirk R Gustafson
Neopetrotaurines A-C, Isoquinoline Alkaloids with an Unprecedented Taurine Bridge from the Sponge Neopetrosia sp. Journal of natural products (2024)
Hayato Kouno, Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, Masuo Goto, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Isolation, Characterization, and Antiproliferative Activity of Terpenoids from the Tropical Plant Turraea delphinensis . Journal of natural products 87 (7) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Maria Orfanoudaki, Rhone K Akee, Lucero Martínez-Fructuoso, Dongdong Wang, James A Kelley, Emily A Smith, Curtis J Henrich, Martin J Schnermann, Barry R Oâ Keefe, Tanja Grkovic
Formation of Trideuteromethylated Artifacts of Pyrrole-Containing Natural Products. Journal of natural products (2024)
Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Unusual Vilasinin-Class Limonoids from Trichilia rubescens . Molecules (Basel, Switzerland) 29 (3) (2024)
Ayano Kobayashi, Yohei Saito, Katsunori Miyake, Shuichi Fukuyoshi, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora . Journal of natural products (2024)
Quan T Khong, Emily A Smith, Karen L Wendt, Masoumeh Dalilian, Ekaterina I Goncharova, Isaac Brownell, Robert H Cichewicz, Curtis J Henrich, John A A Beutler, Barry R Oâ Keefe, Lin Du
Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways. Journal of natural products 87 (7) (2024)
Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Unusual Vilasinin-Class Limonoids from Trichilia rubescens . Molecules (Basel, Switzerland) 29 (3) (2024)
Maria Orfanoudaki, Rhone K Akee, Lucero Martínez-Fructuoso, Dongdong Wang, James A Kelley, Emily A Smith, Curtis J Henrich, Martin J Schnermann, Barry R Oâ Keefe, Tanja Grkovic
Formation of Trideuteromethylated Artifacts of Pyrrole-Containing Natural Products. Journal of natural products 87 (2) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Unusual Vilasinin-Class Limonoids from Trichilia rubescens . Molecules (Basel, Switzerland) 29 (3) (2024)
Taylor B Smallwood, Lauren R H Krumpe, Colton D Payne, Victoria G Klein, Barry R Oâ Keefe, Richard J Clark, Christina I Schroeder, K Johan Rosengren
Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analogues. Chemical science 15 (33) (2024)
Hayato Kouno, Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, Masuo Goto, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Isolation, Characterization, and Antiproliferative Activity of Terpenoids from the Tropical Plant Turraea delphinensis . Journal of natural products 87 (7) (2024)
Taylor B Smallwood, Lauren R H Krumpe, Colton D Payne, Victoria G Klein, Barry R Oâ Keefe, Richard J Clark, Christina I Schroeder, K Johan Rosengren
Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analogues. Chemical science 15 (33) (2024)
Quan T Khong, Emily A Smith, Karen L Wendt, Masoumeh Dalilian, Ekaterina I Goncharova, Isaac Brownell, Robert H Cichewicz, Curtis J Henrich, John A A Beutler, Barry R Oâ Keefe, Lin Du
Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways. Journal of natural products 87 (7) (2024)
Ayano Kobayashi, Yohei Saito, Katsunori Miyake, Shuichi Fukuyoshi, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora . Journal of natural products 87 (2) (2024)
Dongdong Wang, Wei Jiang, Mehal Churiwal, Katrina Jia, Sarath P D Senadeera, Heidi R Bokesch, Girma M Woldemichael, Yong Kim, Robert G Hawley, Jun S Wei, Javed Khan, Barry R Oâ Keefe, John A A Beutler, Kirk R Gustafson
Neopetrotaurines A-C, Isoquinoline Alkaloids with an Unprecedented Taurine Bridge from the Sponge Neopetrosia sp. Journal of natural products 87 (2) (2024)
Maria Orfanoudaki, Rhone K Akee, Lucero Martínez-Fructuoso, Dongdong Wang, James A Kelley, Emily A Smith, Curtis J Henrich, Martin J Schnermann, Barry R Oâ Keefe, Tanja Grkovic
Formation of Trideuteromethylated Artifacts of Pyrrole-Containing Natural Products. Journal of natural products 87 (2) (2024)
Sarath P D Senadeera, Dongdong Wang, Brice A P Wilson, Emily A Smith, Antony Wamiru, Juliana A Martinez Fiesco, Lin Du, Ping Zhang, Barry R Oâ Keefe, John A A Beutler
Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha. Journal of natural products (2024)
Sarath P D Senadeera, Dongdong Wang, Brice A P Wilson, Emily A Smith, Antony Wamiru, Juliana A Martinez Fiesco, Lin Du, Ping Zhang, Barry R Oâ Keefe, John A A Beutler
Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha. Journal of natural products 87 (8) (2024)
Quan T Khong, Emily A Smith, Karen L Wendt, Masoumeh Dalilian, Ekaterina I Goncharova, Isaac Brownell, Robert H Cichewicz, Curtis J Henrich, John A A Beutler, Barry R Oâ Keefe, Lin Du
Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways. Journal of natural products (2024)
Hayato Kouno, Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, Masuo Goto, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Isolation, Characterization, and Antiproliferative Activity of Terpenoids from the Tropical Plant Turraea delphinensis . Journal of natural products (2024)
Ayano Kobayashi, Yohei Saito, Katsunori Miyake, Shuichi Fukuyoshi, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora . Journal of natural products 87 (2) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Sarath P D Senadeera, Dongdong Wang, Brice A P Wilson, Emily A Smith, Antony Wamiru, Juliana A Martinez Fiesco, Lin Du, Ping Zhang, Barry R Oâ Keefe, John A A Beutler
Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha. Journal of natural products 87 (8) (2024)
Brice A P Wilson, Ning Li, Juliana A Martinez Fiesco, Masoumeh Dalilian, Dongdong Wang, Emily A Smith, Antony Wamiru, Rohan Shah, Ekaterina I Goncharova, John A A Beutler, Tanja Grkovic, Ping Zhang, Barry R Oâ Keefe
Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors. ACS pharmacology & translational science 6 (4) (2023)
Lin Du, Brice A P Wilson, Ning Li, Rohan Shah, Masoumeh Dalilian, Dongdong Wang, Emily A Smith, Antony Wamiru, Ekaterina I Goncharova, Ping Zhang, Barry R Oâ Keefe
Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases. Journal of natural products (2023)
Aakansha Nangarlia, Farah Fazloon Hassen, Gabriela Canziani, Praneeta Bandi, Choya Talukder, Fengwen Zhang, Douglas Krauth, Ebony N Gary, David B Weiner, Paul Bieniasz, Sonia Navas-Martin, Barry R Oâ Keefe, Charles Gotuaco Ang, Irwin M Chaiken
Irreversible Inactivation of SARS-CoV-2 by Lectin Engagement with Two Glycan Clusters on the Spike Protein. Biochemistry (2023)
Jason R Evans, Rhone K Akee, Shaurya Chanana, Grant D McConachie, Christopher C Thornburg, Tanja Grkovic, Barry R Oâ Keefe
National Cancer Institute (NCI) Program for Natural Product Discovery: Exploring NCI-60 Screening Data of Natural Product Samples with Artificial Neural Networks. ACS omega 8 (10) (2023)
Brice A P Wilson, Ning Li, Juliana A Martinez Fiesco, Masoumeh Dalilian, Dongdong Wang, Emily A Smith, Antony Wamiru, Rohan Shah, Ekaterina I Goncharova, John A A Beutler, Tanja Grkovic, Ping Zhang, Barry R Oâ Keefe
Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors. ACS pharmacology & translational science 6 (4) (2023)
Lucero Martínez-Fructuoso, S J Ryan Arends, Vitor F Freire, Jason R Evans, Sean DeVries, Brian D Peyser, Rhone K Akee, Christopher C Thornburg, Rohitesh Kumar, Susan Ensel, Gina M Morgan, Grant D McConachie, Nathan Veeder, Leonard R Duncan, Tanja Grkovic, Barry R Oâ Keefe
Screen for New Antimicrobial Natural Products from the NCI Program for Natural Product Discovery Prefractionated Extract Library. ACS infectious diseases (2023)
Jason R Evans, Rhone K Akee, Shaurya Chanana, Grant D McConachie, Christopher C Thornburg, Tanja Grkovic, Barry R Oâ Keefe
National Cancer Institute (NCI) Program for Natural Product Discovery: Exploring NCI-60 Screening Data of Natural Product Samples with Artificial Neural Networks. ACS omega 8 (10) (2023)
Brice A P Wilson, Ning Li, Juliana A Martinez Fiesco, Masoumeh Dalilian, Dongdong Wang, Emily A Smith, Antony Wamiru, Rohan Shah, Ekaterina I Goncharova, John A A Beutler, Tanja Grkovic, Ping Zhang, Barry R Oâ Keefe
Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors. ACS pharmacology & translational science 6 (4) (2023)
Brice A P Wilson, Ning Li, Juliana A Martinez Fiesco, Masoumeh Dalilian, Dongdong Wang, Emily A Smith, Antony Wamiru, Rohan Shah, Ekaterina I Goncharova, John A A Beutler, Tanja Grkovic, Ping Zhang, Barry R Oâ Keefe
Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors. ACS pharmacology & translational science 6 (4) (2023)
Xiangrong Tian, Dongdong Wang, Wei Jiang, Heidi R Bokesch, Brice A P Wilson, Barry R Oâ Keefe, Kirk R Gustafson
Rare Caulamidine Hexacyclic Alkaloids from the Marine Ascidian Polyandrocarpa sp. Journal of natural products (2023)
Wei Jiang, Xiangrong Tian, Dongdong Wang, Heidi R Bokesch, Cheryl L Thomas, Girma M Woldemichael, Berkley E Gryder, Jun S Wei, Young K Song, Hsien-Chao Chou, Javed Khan, Barry R Oâ Keefe, Kirk R Gustafson
Dentithecamides A-H, Diacylated Zoanthoxanthin Derivatives with PAX3-FOXO1 Inhibitory Activity from the Hydroid Dentitheca habereri . Journal of natural products 85 (5) (2022)
Quan T Khong, Dong-Hao Li, Brice A P Wilson, Kalina Ranguelova, Masoumeh Dalilian, Emily A Smith, Antony Wamiru, Ekaterina I Goncharova, Tanja Grkovic, Donna Voeller, Stanley Lipkowitz, Martin J Schnermann, Barry R Oâ Keefe, Lin Du
Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL-B. Organic letters 24 (51) (2022)
Shayan G Borhani, Max Z Levine, Lauren R H Krumpe, Jennifer Wilson, Curtis J Henrich, Barry R Oâ Keefe, Donald Lo, Gurusingham Sittampalam, Alexander G Godfrey, R Dwayne Lunsford, Venkata Mangalampalli, Dingyin Tao, Christopher A LeClair, Aaron Thole, Douglas Frey, James Swartz, Govind Rao
An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics. bioRxiv : the preprint server for biology (2022)
Quan T Khong, Dong-Hao Li, Brice A P Wilson, Kalina Ranguelova, Masoumeh Dalilian, Emily A Smith, Antony Wamiru, Ekaterina I Goncharova, Tanja Grkovic, Donna Voeller, Stanley Lipkowitz, Martin J Schnermann, Barry R Oâ Keefe, Lin Du
Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL-B. Organic letters 24 (51) (2022)
Natalia Teleshova, Marla J Keller, José A Fernández Romero, Barbara A Friedland, George W Creasy, Marlena G Plagianos, Laurie Ray, Patrick Barnable, Larisa Kizima, Aixa Rodriguez, Nadjet Cornejal, Claudia Melo, Gearoff Cruz Rodriguez, Sampurna Mukhopadhyay, Giulia Calenda, Shweta U Sinkar, Thierry Bonnaire, Asa Wesenberg, Shimin Zhang, Kyle Kleinbeck, Kenneth Palmer, Mohcine Alami, Barry R Oâ Keefe, Patrick Gillevet, Hong Hur, Yupu Liang, Gabriela Santone, Raina Nakova Fichorova, Tamara Kalir, Thomas M Zydowsky
Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel. PloS one 17 (1) (2022)
Quan T Khong, Dong-Hao Li, Brice A P Wilson, Kalina Ranguelova, Masoumeh Dalilian, Emily A Smith, Antony Wamiru, Ekaterina I Goncharova, Tanja Grkovic, Donna Voeller, Stanley Lipkowitz, Martin J Schnermann, Barry R Oâ Keefe, Lin Du
Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL-B. Organic letters (2022)
Quan T Khong, Dong-Hao Li, Brice A P Wilson, Kalina Ranguelova, Masoumeh Dalilian, Emily A Smith, Antony Wamiru, Ekaterina I Goncharova, Tanja Grkovic, Donna Voeller, Stanley Lipkowitz, Martin J Schnermann, Barry R Oâ Keefe, Lin Du
Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL-B. Organic letters 24 (51) (2022)
Charles S Fermaintt, Thilini Peramuna, Shengxin Cai, Leila Takahashi-Ruiz, Jacob Nathaniel Essif, Corena V Grant, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz, April L Risinger
Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential. Cancers 13 (11) (2021)
Sahar Alsaidi, Nadjet Cornejal, Oneil Mahoney, Claudia Melo, Neeharika Verma, Thierry Bonnaire, Theresa L Chang, Barry R Oâ Keefe, James Sailer, Thomas M Zydowsky, Natalia Teleshova, José A Fernández Romero
Griffithsin and Carrageenan Combination Results in Antiviral Synergy against SARS-CoV-1 and 2 in a Pseudoviral Model. Marine drugs 19 (8) (2021)
Wei Jiang, Dongdong Wang, Brice A P Wilson, Donna Voeller, Heidi R Bokesch, Emily A Smith, Stanley Lipkowitz, Barry R Oâ Keefe, Kirk R Gustafson
Sinularamides A-G, Terpenoid-Derived Spermidine and Spermine Conjugates with Casitas B-Lineage Lymphoma Proto-Oncogene B (Cbl-b) Inhibitory Activities from a Sinularia sp. Soft Coral. Journal of natural products 84 (6) (2021)
Chang-Kwon Kim, Lauren R H Krumpe, Emily A Smith, Curtis J Henrich, Isaac Brownell, Karen L Wendt, Robert H Cichewicz, Barry R Oâ Keefe, Kirk R Gustafson
Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea. Molecules (Basel, Switzerland) 26 (12) (2021)
George S Hanna, Yeun-Mun Choo, Ryan Harbit, Heather Paeth, Sarah Wilde, James Mackle, Jacopo-Umberto Verga, Bethany J Wolf, Olivier P Thomas, Peter L Croot, James Cray, Courtney Thomas, Ling-Zhi Li, Gary Hardiman, Jin-Feng Hu, Xiaojuan Wang, Dharmeshkumar Patel, Raymond F Schinazi, Barry R Oâ Keefe, Mark T Hamann
Contemporary Approaches to the Discovery and Development of Broad-Spectrum Natural Product Prototypes for the Control of Coronaviruses. Journal of natural products 84 (11) (2021)
Wei Jiang, Dongdong Wang, Brice A P Wilson, Unwoo Kang, Heidi R Bokesch, Emily A Smith, Antony Wamiru, Ekaterina I Goncharova, Donna Voeller, Stanley Lipkowitz, Barry R Oâ Keefe, Kirk R Gustafson
Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana. Marine drugs 19 (7) (2021)
Dongdong Wang, Wei Jiang, Chang-Kwon Kim, Heidi R Bokesch, Girma M Woldemichael, Berkley E Gryder, John F Shern, Javed Khan, Barry R Oâ Keefe, John A A Beutler, Kirk R Gustafson
Neopetrothiazide: An Intriguing Pentacyclic Thiazide Alkaloid from the Sponge Neopetrosia sp. Organic letters 23 (9) (2021)
Petra J Pederson, Shengxin Cai, Chase Carver, Douglas R Powell, April L Risinger, Tanja Grkovic, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz
Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea. Journal of natural products 83 (7) (2020)
Corena V Grant, Shengxin Cai, April L Risinger, Huiyun Liang, Barry R Oâ Keefe, John G Doench, Robert H Cichewicz, Susan L Mooberry
CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells. Journal of natural products 83 (10) (2020)
Lauren R H Krumpe, Brice A P Wilson, Christophe Marchand, Suthananda N Sunassee, Alun Bermingham, Wenjie Wang, Edmund Price, Tad Guszczynski, James A Kelley, Kirk R Gustafson, Yves Pommier, K Johan Rosengren, Christina I Schroeder, Barry R Oâ Keefe
Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I. Journal of the American Chemical Society 142 (50) (2020)
Hongyan Ma, Huiyun Liang, Shengxin Cai, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz
An Integrated Strategy for the Detection, Dereplication, and Identification of DNA-Binding Biomolecules from Complex Natural Product Mixtures. Journal of natural products 84 (3) (2020)
Yun-Seo Kil, April L Risinger, Cora L Petersen, Huiyun Liang, Tanja Grkovic, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz
Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of Choerospondias axillaris. Journal of natural products 83 (3) (2020)
Tanja Grkovic, Rhone K Akee, Christopher C Thornburg, Spencer K Trinh, John R Britt, Matthew J Harris, Jason R Evans, Unwoo Kang, Susan Ensel, Curtis J Henrich, Kirk R Gustafson, Joel P Schneider, Barry R Oâ Keefe
National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library. ACS chemical biology 15 (4) (2020)
Julia Krushkal, Simarjeet Negi, Laura M Yee, Jason R Evans, Tanja Grkovic, Alida Palmisano, Jianwen Fang, Hari Sankaran, Lisa Meier McShane, Yingdong Zhao, Barry R Oâ Keefe
Molecular genomic features associated with in vitro response of the NCI-60 cancer cell line panel to natural products. Molecular oncology 15 (2) (2020)
Trong D Tran, Brice A P Wilson, Curtis J Henrich, Louis M Staudt, Lauren R H Krumpe, Emily A Smith, Jarrod King, Karen L Wendt, Alberto M Stchigel, Andrew N Miller, Robert H Cichewicz, Barry R Oâ Keefe, Kirk R Gustafson
Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities. Journal of natural products 82 (1) (2019)
Shengxin Cai, April L Risinger, Cora L Petersen, Tanja Grkovic, Barry R Oâ Keefe, Susan L Mooberry, Robert H Cichewicz
Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines. Journal of natural products 82 (4) (2019)
Katsunori Miyake, Chihiro Morita, Airi Suzuki, Natsuko Matsushita, Yohei Saito, Masuo Goto, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Prenylated Acetophloroglucinol Dimers from Acronychia trifoliolata: Structure Elucidation and Total Synthesis. Journal of natural products 82 (10) (2019)
Fumika Tsurumi, Yuta Miura, Misaki Nakano, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Spiro[3.5]nonenyl Meroterpenoid Lactones, Cryptolaevilactones G-L, an Ionone Derivative, and Total Synthesis of Cryptolaevilactone M from Cryptocarya laevigata. Journal of natural products 82 (9) (2019)
A Jonathan Singh, Alexander P Gorka, Heidi R Bokesch, Antony Wamiru, Barry R Oâ Keefe, Martin J Schnermann, Kirk R Gustafson
Harnessing Natural Product Diversity for Fluorophore Discovery: Naturally Occurring Fluorescent Hydroxyanthraquinones from the Marine Crinoid Pterometra venusta. Journal of natural products 81 (12) (2018)
Christopher C Thornburg, John R Britt, Jason R Evans, Rhone K Akee, James A Whitt, Spencer K Trinh, Matthew J Harris, Jerell R Thompson, Teresa L Ewing, Suzanne M Shipley, Paul G Grothaus, David J Newman, Joel P Schneider, Tanja Grkovic, Barry R Oâ Keefe
NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening. ACS chemical biology 13 (9) (2018)
Nina Derby, Manjari Lal, Meropi Aravantinou, Larisa Kizima, Patrick Barnable, Aixa Rodriguez, Manshun Lai, Asa Wesenberg, Shweta Ugaonkar, Keith Levendosky, Olga Mizenina, Kyle Kleinbeck, Jeffrey D Lifson, M Melissa Peet, Zachary Lloyd, Michael Benson, Walid Heneine, Barry R Oâ Keefe, Melissa Robbiani, Elena Martinelli, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Natalia Teleshova, José A Fernández-Romero, Thomas M Zydowsky
Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo. Nature communications 9 (1) (2018)
Misa Takeuchi, Yohei Saito, Masuo Goto, Katsunori Miyake, David J Newman, Barry R Oâ Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa Goto
Antiproliferative Alkaloids from Alangium longiflorum, an Endangered Tropical Plant Species. Journal of natural products 81 (8) (2018)