Axel T Brunger

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 30

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

eLife

Nature

Nature cell biology

Stanford University

Technische Universität München (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Stanford University

United States

Professor :: Molecular and Cellular Physiology

Howard Hughes Medical Institute - Stanford University

United States

Investigator

Yale University

United States

Professor :: Molecular Biophysics and Biochemistry

Yale University

United States

Associate Pofessor :: Molecular Biophysics and Biochemistry

Yale University

United States

Assistant Professor :: Molecular Biophysics and Biochemistry

Education History

Technische Universität München

Germany

PHD :: Biophysics

Publications

Yousuf A Khan, K Ian White, Richard A Pfuetzner, Bharti Singal, Luis Esquivies, Garvey Mckenzie, Fang Liu, Katherine DeLong, Uchoer B Choi, Elizabeth Montabana, Theresa Mclaughlin, William T Wickner, Axel T Brunger
Sec18 side-loading is essential for universal SNARE recycling across cellular contexts. bioRxiv : the preprint server for biology (2024)
Richard G Held, Jiahao Liang, Axel T Brunger
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Chuchu Wang, Wenhong Jiang, Jeremy Leitz, Kailu Yang, Luis Esquivies, Xing Wang, Xiaotao Shen, Richard G Held, Daniel J Adams, Tamara Basta, Lucas Hampton, Ruiqi Jian, Lihua Jiang, Michael H B Stowell, Wolfgang Baumeister, Qiang Guo, Axel T Brunger
Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature (2024)
Chuchu Wang, Wenhong Jiang, Jeremy Leitz, Kailu Yang, Luis Esquivies, Xing Wang, Xiaotao Shen, Richard G Held, Daniel J Adams, Tamara Basta, Lucas Hampton, Ruiqi Jian, Lihua Jiang, Michael H B Stowell, Wolfgang Baumeister, Qiang Guo, Axel T Brunger
Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature 631 (8022) (2024)
Chuchu Wang, Wenhong Jiang, Jeremy Leitz, Kailu Yang, Luis Esquivies, Xing Wang, Xiaotao Shen, Richard G Held, Daniel J Adams, Tamara Basta, Lucas Hampton, Ruiqi Jian, Lihua Jiang, Michael H B Stowell, Wolfgang Baumeister, Qiang Guo, Axel T Brunger
Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature 631 (8022) (2024)
Chuchu Wang, Wenhong Jiang, Jeremy Leitz, Kailu Yang, Luis Esquivies, Xing Wang, Xiaotao Shen, Richard G Held, Daniel J Adams, Tamara Basta, Lucas Hampton, Ruiqi Jian, Lihua Jiang, Michael H B Stowell, Wolfgang Baumeister, Qiang Guo, Axel T Brunger
Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature 631 (8022) (2024)
Chuchu Wang, Kai Zhang, Bin Cai, Jillian E Haller, Kathryn E Carnazza, Jiaojiao Hu, Chunyu Zhao, Zhiqi Tian, Xiao Hu, Daniel Hall, Jiali Qiang, Shouqiao Hou, Zhenying Liu, Jinge Gu, Yao-Yang Zhang, Kim B Seroogy, Jacqueline Burré, Yanshan Fang, Cong Liu, Axel T Brunger, Dan Li, Jiajie Diao
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates. Nature cell biology (2024)
Richard G Held, Jiahao Liang, Axel T Brunger
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Jeremy Leitz, Chuchu Wang, Luis Esquivies, John J Peters, Nisha Gopal, Richard A Pfuetzner, Austin L Wang, Axel T Brunger
Observing isolated synaptic vesicle association and fusion ex vivo. Nature protocols (2024)
Richard G Held, Jiahao Liang, Axel T Brunger
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Richard G Held, Jiahao Liang, Axel T Brunger
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Chuchu Wang, Wenhong Jiang, Jeremy Leitz, Kailu Yang, Luis Esquivies, Xing Wang, Xiaotao Shen, Richard G Held, Daniel J Adams, Tamara Basta, Lucas Hampton, Ruiqi Jian, Lihua Jiang, Michael H B Stowell, Wolfgang Baumeister, Qiang Guo, Axel T Brunger
Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature 631 (8022) (2024)
Chuchu Wang, Wenhong Jiang, Jeremy Leitz, Kailu Yang, Luis Esquivies, Xing Wang, Xiaotao Shen, Richard Held, Daniel J Adams, Tamara Basta, Lucas Hampton, Ruiqi Jian, Lihua Jiang, Michael H B Stowell, Wolfgang Baumeister, Qiang Guo, Axel T Brunger
Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature (2024)
Chuchu Wang, Kai Zhang, Bin Cai, Jillian E Haller, Kathryn E Carnazza, Jiaojiao Hu, Chunyu Zhao, Zhiqi Tian, Xiao Hu, Daniel Hall, Jiali Qiang, Shouqiao Hou, Zhenying Liu, Jinge Gu, Yao-Yang Zhang, Kim B Seroogy, Jacqueline Burré, Yanshan Fang, Cong Liu, Axel T Brunger, Dan Li, Jiajie Diao
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates. Nature cell biology 26 (8) (2024)
Kailu Yang, Chuchu Wang, Alex J B Kreutzberger, K Ian White, Richard A Pfuetzner, Luis Esquivies, Tomas Kirchhausen, Axel T Brunger
Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Ying Lai, Chunyu Zhao, Zhiqi Tian, Chuchu Wang, Jiaqi Fan, Xiao Hu, Jia Tu, Tihui Li, Jeremy Leitz, Richard A Pfuetzner, Zhengtao Liu, Shengnan Zhang, Zhaoming Su, Jacqueline Burré, Dan Li, Thomas C Südhof, Zheng-Jiang Zhu, Cong Liu, Axel T Brunger, Jiajie Diao
Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering. Proceedings of the National Academy of Sciences of the United States of America 120 (44) (2023)
Kailu Yang, Chuchu Wang, Alex J B Kreutzberger, K Ian White, Richard A Pfuetzner, Luis Esquivies, Tomas Kirchhausen, Axel T Brunger
Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Kailu Yang, Chuchu Wang, Alex J B Kreutzberger, Ravi Ojha, Suvi Kuivanen, Sergio Couoh-Cardel, Serena Muratcioglu, Timothy J Eisen, K Ian White, Richard G Held, Subu Subramanian, Kendra Marcus, Richard A Pfuetzner, Luis Esquivies, Catherine A Doyle, John Kuriyan, Olli Vapalahti, Giuseppe Balistreri, Tom Kirchhausen, Axel T Brunger
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein. Proceedings of the National Academy of Sciences of the United States of America 119 (40) (2022)
Ying Lai, Giorgio Fois, Jose R Flores, Michael J Tuvim, Qiangjun Zhou, Kailu Yang, Jeremy Leitz, John Jacob Peters, Yunxiang Zhang, Richard A Pfuetzner, Luis Esquivies, Philip Jones, Manfred Frick, Burton F Dickey, Axel T Brunger
Inhibition of calcium-triggered secretion by hydrocarbon-stapled peptides. Nature 603 (7903) (2022)
Klaudia Jaczynska, Luis Esquivies, Richard A Pfuetzner, Baris Alten, Kyle D Brewer, Qiangjun Zhou, Ege T Kavalali, Axel T Brunger, Josep Rizo
Analysis of tripartite Synaptotagmin-1-SNARE-complexin-1 complexes in solution. FEBS open bio (2022)
Stijn van Dorp, Ruoyi Qiu, Ucheor B Choi, Minnie M Wu, Michelle Yen, Michael Kirmiz, Axel T Brunger, Richard S Lewis
Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1. eLife 10 (2021)
Hongki Song, Thomas L Torng, Amy S Orr, Axel T Brunger, William T Wickner
Sec17/Sec18 can support membrane fusion without help from completion of SNARE zippering. eLife 10 (2021)
Monarin Uervirojnangkoorn, Artem Y Lyubimov, Qiangjun Zhou, William I Weis, Axel T Brunger
Resolving indexing ambiguities in X-ray free-electron laser diffraction patterns. Acta crystallographica. Section D, Structural biology 75 (Pt 2) (2019)
Steven C Wilson, K Ian White, Qiangjun Zhou, Richard A Pfuetzner, Ucheor B Choi, Thomas C Südhof, Axel T Brunger
Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing. The EMBO journal 38 (22) (2019)
Ucheor B Choi, Minglei Zhao, K Ian White, Richard A Pfuetzner, Luis Esquivies, Qiangjun Zhou, Axel T Brunger
NSF-mediated disassembly of on- and off-pathway SNARE complexes and inhibition by complexin. eLife 7 (2018)
K Ian White, Minglei Zhao, Ucheor B Choi, Richard A Pfuetzner, Axel T Brunger
Structural principles of SNARE complex recognition by the AAA+ protein NSF. eLife 7 (2018)
Ucheor B Choi, Minglei Zhao, Yunxiang Zhang, Ying Lai, Axel T Brunger
Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex. eLife 5 (2016)
Artem Y Lyubimov, Monarin Uervirojnangkoorn, Oliver B Zeldin, Qiangjun Zhou, Minglei Zhao, Aaron S Brewster, Tara Michels-Clark, James M Holton, Nicholas K Sauter, William I Weis, Axel T Brunger
Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex. eLife 5 (2016)
Monarin Uervirojnangkoorn, Oliver B Zeldin, Artem Y Lyubimov, Johan Hattne, Aaron S Brewster, Nicholas K Sauter, Axel T Brunger, William I Weis
Enabling X-ray free electron laser crystallography for challenging biological systems from a limited number of crystals. eLife 4 (2015)
Daniel A Keedy, Lillian R Kenner, Matthew Warkentin, Rahel A Woldeyes, Jesse B Hopkins, Michael C Thompson, Aaron S Brewster, Andrew H Van Benschoten, Elizabeth L Baxter, Monarin Uervirojnangkoorn, Scott E McPhillips, Jinhu Song, Roberto Alonso-Mori, James M Holton, William I Weis, Axel T Brunger, S Michael Soltis, Henrik Lemke, Ana Gonzalez, Nicholas K Sauter, Aina E Cohen, Henry van den Bedem, Robert E Thorne, Brian K Shoichet
Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography. eLife 4 (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

Axel T Brunger