Josep Rizo

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 48

Top Topics

Molecular Dynamics Simulations

Endoscopic Submucosal Dissection

Top Venues

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Junjie Xu, Victoria Esser, Katarzyna Gołębiowska-Mendroch, Agnieszka A Bolembach, Josep Rizo
Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region. bioRxiv : the preprint server for biology (2024)
Josep Rizo, Levent Sari, Klaudia Jaczynska, Christian Rosenmund, Milo M Lin
Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Junjie Xu, Victoria Esser, Katarzyna Gołębiowska-Mendroch, Agnieszka A Bolembach, Josep Rizo
Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region. bioRxiv : the preprint server for biology (2024)
Estelle Toulme, Andrea Salazar Lázaro, Thorsten Trimbuch, Josep Rizo, Christian Rosenmund
Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface. bioRxiv : the preprint server for biology (2024)
Lukasz A Joachimiak, Sofia Bali, Ruhar Singh, Pawel M Wydorski, Aleksandra Wosztyl, Valerie Ann Perez, Dailu Chen, Josep Rizo
Ensemble-based design of tau to inhibit aggregation while preserving biological activity. Research square (2024)
Josep Rizo, Levent Sari, Klaudia Jaczynska, Christian Rosenmund, Milo M Lin
Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Klaudia Jaczynska, Victoria Esser, Junjie Xu, Levent Sari, Milo M Lin, Christian Rosenmund, Josep Rizo
A lever hypothesis for Synaptotagmin-1 action in neurotransmitter release. bioRxiv : the preprint server for biology (2024)
Estelle Toulme, Andrea Salazar Lázaro, Thorsten Trimbuch, Josep Rizo, Christian Rosenmund
Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface. bioRxiv : the preprint server for biology (2024)
Josep Rizo, Levent Sari, Klaudia Jaczynska, Christian Rosenmund, Milo M Lin
Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Josep Rizo, Levent Sari, Klaudia Jaczynska, Christian Rosenmund, Milo M Lin
Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Junjie Xu, Victoria Esser, Katarzyna Gołębiowska-Mendroch, Agnieszka A Bolembach, Josep Rizo
Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region. bioRxiv : the preprint server for biology (2024)
Klaudia Jaczynska, Victoria Esser, Junjie Xu, Levent Sari, Milo M Lin, Christian Rosenmund, Josep Rizo
A lever hypothesis for Synaptotagmin-1 action in neurotransmiter release. bioRxiv : the preprint server for biology (2024)
Sofia Bali, Ruhar Singh, Pawel M Wydorski, Aleksandra Wosztyl, Valerie Ann Perez, Dailu Chen, Josep Rizo, Lukasz A Joachimiak
Ensemble-based design of tau to inhibit aggregation while preserving biological activity. Research square (2024)
Klaudia Jaczynska, Victoria Esser, Junjie Xu, Levent Sari, Milo M Lin, Christian Rosenmund, Josep Rizo
A lever hypothesis for Synaptotagmin-1 action in neurotransmiter release. bioRxiv : the preprint server for biology (2024)
Junjie Xu, Victoria Esser, Katarzyna Gołębiowska-Mendroch, Agnieszka A Bolembach, Josep Rizo
Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region. bioRxiv : the preprint server for biology (2024)
Josep Rizo, Levent Sari, Klaudia Jaczynska, Christian Rosenmund, Milo M Lin
Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America 121 (16) (2024)
Junjie Xu, Victoria Esser, Katarzyna Gołębiowska-Mendroch, Agnieszka A Bolembach, Josep Rizo
Control of Munc13-1 Activity by Autoinhibitory Interactions Involving the Variable N-terminal Region. bioRxiv : the preprint server for biology (2024)
Julita Chlebowicz, William P Russ, Dailu Chen, Anthony R Vega, Steven Vernino, Charles L White, Josep Rizo, Lukasz A Joachimiak, Marc I Diamond
Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation. Science advances 9 (43) (2023)
Jinge Gu, Xiaoming Zhou, Lillian Sutherland, Masato Kato, Klaudia Jaczynska, Josep Rizo, Steven L McKnight
Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch. Proceedings of the National Academy of Sciences of the United States of America 120 (41) (2023)
Sofia Bali, Ruhar Singh, Pawel M Wydorski, Aleksandra Wosztyl, Valerie Ann Perez, Dailu Chen, Josep Rizo, Lukasz A Joachimiak
Ensemble-based design of tau to inhibit aggregation while preserving biological activity. bioRxiv : the preprint server for biology (2023)
Sofia Bali, Ruhar Singh, Pawel M Wydorski, Aleksandra Wosztyl, Valerie Ann Perez, Dailu Chen, Josep Rizo, Lukasz A Joachimiak
Ensemble-based design of tau to inhibit aggregation while preserving biological activity. bioRxiv : the preprint server for biology (2023)
Jinge Gu, Xiaoming Zhou, Lillian Sutherland, Masato Kato, Klaudia Jaczynska, Josep Rizo, Steven L McKnight
Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch. bioRxiv : the preprint server for biology (2023)
Mengjia Huang, Ya Wang, Chun Hin Chow, Karolina Stepien, Karen Indrawinata, Peter Argiropoulos, Xiaoyu Xie, Kyoko Sugita, Chi-Wei Tien, Soomin Lee, Philippe P Monnier, Josep Rizo, Shangbang Gao, Shuzo Sugita
Double mutation of open syntaxin and UNC-18 P334A leads to excitatory-inhibitory imbalance and impairs multiple aspects of C. elegans behavior. bioRxiv : the preprint server for biology (2023)
Ioannis Tsagakis, Josep Rizo
An open chat with… Josep Rizo. FEBS open bio (2023)
Yun-Zu Pan, Qiren Liang, Diana R Tomchick, Jef K De Brabander, Josep Rizo
Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Communications biology 6 (1) (2023)
Carlos M Roggero, Victoria Esser, Lingling Duan, Allyson M Rice, Shihong Ma, Ganesh V Raj, Michael K Rosen, Zhi-Ping Liu, Josep Rizo
Poly-glutamine-dependent self-association as a potential mechanism for regulation of androgen receptor activity. PloS one 17 (1) (2022)
Klaudia Jaczynska, Luis Esquivies, Richard A Pfuetzner, Baris Alten, Kyle D Brewer, Qiangjun Zhou, Ege T Kavalali, Axel T Brunger, Josep Rizo
Analysis of tripartite Synaptotagmin-1-SNARE-complexin-1 complexes in solution. FEBS open bio (2022)
Josep Rizo, Guillaume David, Michael E Fealey, Klaudia Jaczynska
On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release. FEBS open bio 12 (11) (2022)
Karolina P Stepien, Junjie Xu, Xuewu Zhang, Xiao-Chen Bai, Josep Rizo
SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex. Science advances 8 (25) (2022)
Josep Rizo, Levent Sari, Yife Qi, Wonpil Im, Milo M Lin
All-atom molecular dynamics simulations of Synaptotagmin-SNARE-complexin complexes bridging a vesicle and a flat lipid bilayer. eLife 11 (2022)
Ian R Humphreys, Jimin Pei, Minkyung Baek, Aditya Krishnakumar, David Baker, Sergey Ovchinnikov, Jing Zhang, Travis J Ness, Sudeep Banjade, Saket Rahul Bagde, Viktoriya G Stancheva, Xiao-Han Li, Kaixian Liu, Zhi Zheng, Daniel J Barrero, Upasana Roy, Jochen Kuper, Israel S Fernández, Barnabas Szakal, Dana Branzei, Josep Rizo, Caroline Kisker, Eric C Greene, Sue Biggins, Scott Keeney, Elizabeth A Miller, J Christopher Fromme, Tamara L Hendrickson, Nick V Grishin, Julien S Baker
Computed structures of core eukaryotic protein complexes. Science (New York, N.Y.) 374 (6573) (2021)
Rashmi Voleti, Sofia Bali, Jaime Guerrero, Jared Smothers, Charis Springhower, Gerardo A Acosta, Kyle D Brewer, Fernando Albericio, Josep Rizo
Evaluation of the tert-butyl group as a probe for NMR studies of macromolecular complexes. Journal of biomolecular NMR 75 (8-9) (2021)
Marcial Camacho, Bradley Quade, Thorsten Trimbuch, Junjie Xu, Levent Sari, Josep Rizo, Christian Rosenmund
Control of neurotransmitter release by two distinct membrane-binding faces of the Munc13-1 C1C2B region. eLife 10 (2021)
Karolina P Stepien, Josep Rizo
Synaptotagmin-1-, Munc18-1-, and Munc13-1-dependent liposome fusion with a few neuronal SNAREs. Proceedings of the National Academy of Sciences of the United States of America 118 (4) (2021)
Josep Rizo, Klaudia Jaczynska, Karolina P Stepien
Molecular machinery turns full circle. eLife 10 (2021)
Rashmi Voleti, Klaudia Jaczynska, Josep Rizo
Ca2+-dependent release of synaptotagmin-1 from the SNARE complex on phosphatidylinositol 4,5-bisphosphate-containing membranes. eLife 9 (2020)
Magdalena Magdziarek, Agnieszka A Bolembach, Karolina P Stepien, Bradley Quade, Xiaoxia Liu, Josep Rizo
Re-examining how Munc13-1 facilitates opening of syntaxin-1. Protein science : a publication of the Protein Society 29 (6) (2020)
Yun-Zu Pan, Xiaoxia Liu, Josep Rizo
Analysis of asymmetry in lipid and content mixing assays with reconstituted proteoliposomes containing the neuronal SNAREs. Scientific reports 10 (1) (2020)
Chi-Wei Tien, Bin Yu, Mengjia Huang, Karolina P Stepien, Kyoko Sugita, Xiaoyu Xie, Liping Han, Philippe P Monnier, Mei Zhen, Josep Rizo, Shangbang Gao, Shuzo Sugita
Open syntaxin overcomes exocytosis defects of diverse mutants in C. elegans. Nature communications 11 (1) (2020)
Karolina P Stepien, Eric A Prinslow, Josep Rizo
Munc18-1 is crucial to overcome the inhibition of synaptic vesicle fusion by αSNAP. Nature communications 10 (1) (2019)
Bradley Quade, Marcial Camacho, Xiaowei Zhao, Marta Orlando, Thorsten Trimbuch, Junjie Xu, Wei Li, Daniela Nicastro, Christian Rosenmund, Josep Rizo
Membrane bridging by Munc13-1 is crucial for neurotransmitter release. eLife 8 (2019)
Eric A Prinslow, Karolina P Stepien, Yun-Zu Pan, Junjie Xu, Josep Rizo
Multiple factors maintain assembled trans-SNARE complexes in the presence of NSF and αSNAP. eLife 8 (2019)
Xiaoxia Liu, Alpay Burak Seven, Junjie Xu, Victoria Esser, Lijing Su, Cong Ma, Josep Rizo
Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion. Nature protocols 12 (9) (2017)
Ewa Sitarska, Junjie Xu, Seungmee Park, Xiaoxia Liu, Bradley Quade, Karolina Stepien, Kyoko Sugita, Chad A Brautigam, Shuzo Sugita, Josep Rizo
Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion. eLife 6 (2017)
Eric A Prinslow, Chad A Brautigam, Josep Rizo
Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes. eLife 6 (2017)
Seungmee Park, Na-Ryum Bin, Bin Yu, Raymond Wong, Ewa Sitarska, Kyoko Sugita, Ke Ma, Junjie Xu, Chi-Wei Tien, Arash Algouneh, Ekaterina Turlova, Siyan Wang, Pranay Siriya, Waleed Shahid, Lorraine Kalia, Zhong-Ping Feng, Philippe P Monnier, Hong-Shuo Sun, Mei Zhen, Shangbang Gao, Josep Rizo, Shuzo Sugita
UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (36) (2017)
Junjie Xu, Marcial Camacho, Yibin Xu, Victoria Esser, Xiaoxia Liu, Thorsten Trimbuch, Yun-Zu Pan, Cong Ma, Diana R Tomchick, Christian Rosenmund, Josep Rizo
Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN. eLife 6 (2017)
Xiaoxia Liu, Alpay Burak Seven, Marcial Camacho, Victoria Esser, Junjie Xu, Thorsten Trimbuch, Bradley Quade, Lijing Su, Cong Ma, Christian Rosenmund, Josep Rizo
Functional synergy between the Munc13 C-terminal C1 and C2 domains. eLife 5 (2016)