Dan Li

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 47

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Cell discovery

Nature structural & molecular biology

University of California, Los Angeles

Peking University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California, Los Angeles

United States

Postdoc

Education History

Peking University

China

PHD :: School of Life Sciences

Jilin University

China

BSC

Publications

Wanbing Zhao, Kaien Liu, Yun Fan, Qinyue Zhao, Youqi Tao, Mengwei Zhang, Linhua Gan, Wenbo Yu, Bo Sun, Dan Li, Cong Liu, Jian Wang
Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies. Cell discovery 10 (1) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Shuang Hou, Jiaojiao Hu, Zhaowei Yu, Dan Li, Cong Liu, Yong Zhang
Machine learning predictor PSPire screens for phase-separating proteins lacking intrinsically disordered regions. Nature communications 15 (1) (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Shuang Hou, Jiaojiao Hu, Zhaowei Yu, Dan Li, Cong Liu, Yong Zhang
Machine learning predictor PSPire screens for phase-separating proteins lacking intrinsically disordered regions. Nature communications 15 (1) (2024)
Chuchu Wang, Kai Zhang, Bin Cai, Jillian E Haller, Kathryn E Carnazza, Jiaojiao Hu, Chunyu Zhao, Zhiqi Tian, Xiao Hu, Daniel Hall, Jiali Qiang, Shouqiao Hou, Zhenying Liu, Jinge Gu, Yao-Yang Zhang, Kim B Seroogy, Jacqueline Burré, Yanshan Fang, Cong Liu, Axel T Brunger, Dan Li, Jiajie Diao
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates. Nature cell biology (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Qinyue Zhao, Yun Fan, Wanbing Zhao, You Ni, Youqi Tao, Jiang Bian, Wencheng Xia, Wenbo Yu, Zhen Fan, Cong Liu, Bo Sun, Weidong Le, Wensheng Li, Jian Wang, Dan Li
A Tau PET tracer PBB3 binds to TMEM106B amyloid fibril in brain. Cell discovery 10 (1) (2024)
Qinyue Zhao, Yun Fan, Wanbing Zhao, You Ni, Youqi Tao, Jiang Bian, Wencheng Xia, Wenbo Yu, Zhen Fan, Cong Liu, Bo Sun, Weidong Le, Wensheng Li, Jian Wang, Dan Li
A Tau PET tracer PBB3 binds to TMEM106B amyloid fibril in brain. Cell discovery 10 (1) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Qianhui Xu, Huilan Wang, Ruonan Yang, Youqi Tao, Ziying Wang, Shengnan Zhang, Bo Sun, Dan Li, Boxun Lu, Cong Liu
α-Synuclein amyloid fibril directly binds to LC3B and suppresses SQSTM1/p62-mediated selective autophagy. Cell research (2024)
Wanbing Zhao, Kaien Liu, Yun Fan, Qinyue Zhao, Youqi Tao, Mengwei Zhang, Linhua Gan, Wenbo Yu, Bo Sun, Dan Li, Cong Liu, Jian Wang
Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies. Cell discovery 10 (1) (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Chuchu Wang, Chunyu Zhao, Xiao Hu, Jiali Qiang, Zhenying Liu, Jinge Gu, Shengnan Zhang, Dan Li, Yaoyang Zhang, Jacqueline Burré, Jiajie Diao, Cong Liu
N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine. bioRxiv : the preprint server for biology (2024)
Wanbing Zhao, Kaien Liu, Yun Fan, Qinyue Zhao, Youqi Tao, Mengwei Zhang, Linhua Gan, Wenbo Yu, Bo Sun, Dan Li, Cong Liu, Jian Wang
Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies. Cell discovery 10 (1) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Chuchu Wang, Kai Zhang, Bin Cai, Jillian E Haller, Kathryn E Carnazza, Jiaojiao Hu, Chunyu Zhao, Zhiqi Tian, Xiao Hu, Daniel Hall, Jiali Qiang, Shouqiao Hou, Zhenying Liu, Jinge Gu, Yao-Yang Zhang, Kim B Seroogy, Jacqueline Burré, Yanshan Fang, Cong Liu, Axel T Brunger, Dan Li, Jiajie Diao
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates. Nature cell biology 26 (8) (2024)
Chuchu Wang, Chunyu Zhao, Xiao Hu, Jiali Qiang, Zhenying Liu, Jinge Gu, Shengnan Zhang, Dan Li, Yaoyang Zhang, Jacqueline Burré, Jiajie Diao, Cong Liu
N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine. bioRxiv : the preprint server for biology (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Shuang Hou, Jiaojiao Hu, Zhaowei Yu, Dan Li, Cong Liu, Yong Zhang
Machine learning predictor PSPire screens for phase-separating proteins lacking intrinsically disordered regions. Nature communications 15 (1) (2024)
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Binding adaptability of chemical ligands to polymorphic α-synuclein amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Ying Lai, Chunyu Zhao, Zhiqi Tian, Chuchu Wang, Jiaqi Fan, Xiao Hu, Jia Tu, Tihui Li, Jeremy Leitz, Richard A Pfuetzner, Zhengtao Liu, Shengnan Zhang, Zhaoming Su, Jacqueline Burré, Dan Li, Thomas C Südhof, Zheng-Jiang Zhu, Cong Liu, Axel T Brunger, Jiajie Diao
Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering. Proceedings of the National Academy of Sciences of the United States of America 120 (44) (2023)
Youqi Tao, Wencheng Xia, Qinyue Zhao, Huaijiang Xiang, Chao Han, Shenqing Zhang, Wei Gu, Wenjun Tang, Ying Li, Li Tan, Dan Li, Cong Liu
Structural mechanism for specific binding of chemical compounds to amyloid fibrils. Nature chemical biology (2023)
Yichen Li, Shuaiyao Lu, Jinge Gu, Wencheng Xia, Shengnan Zhang, Shenqing Zhang, Yan Wang, Chong Zhang, Yunpeng Sun, Jian Lei, Cong Liu, Zhaoming Su, Juntao Yang, Xiaozhong Peng, Dan Li
SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation. Protein & cell 13 (8) (2022)
Youqi Tao, Yunpeng Sun, Shiran Lv, Wencheng Xia, Kun Zhao, Qianhui Xu, Qinyue Zhao, Lin He, Wei-Dong Le, Yong Wang, Cong Liu, Dan Li
Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology. Nature communications 13 (1) (2022)
Shengnan Zhang, Yi Zhu, Jinxia Lu, Zhenying Liu, Amanda G Lobato, Wen Zeng, Jiaqi Liu, Jiali Qiang, Shuyi Zeng, Yaoyang Zhang, Cong Liu, Jun Liu, Zhuohao He, Rong Grace Zhai, Dan Li
Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology. eLife 11 (2022)
Qi Wang, Zhouxian Li, Shenqing Zhang, Yichen Li, Yan Wang, Zheng Fang, Yanni Ma, Zhen Liu, Weibing Zhang, Dan Li, Cong Liu, Mingliang Ye
Global profiling of arginine dimethylation in regulating protein phase separation by a steric effect-based chemical-enrichment method. Proceedings of the National Academy of Sciences of the United States of America 119 (43) (2022)
Dan Li, Cong Liu
Conformational strains of pathogenic amyloid proteins in neurodegenerative diseases. Nature reviews. Neuroscience 23 (9) (2022)
Li-Qiang Wang, Yeyang Ma, Han-Ye Yuan, Kun Zhao, Mu-Ya Zhang, Qiang Wang, Xi Huang, Wen-Chang Xu, Bin Dai, Jie Chen, Dan Li, Delin Zhang, Zhengzhi Wang, Liangyu Zou, Ping Yin, Cong Liu, Yi Yang
Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion. Nature communications 13 (1) (2022)
Shengnan Zhang, Yu-Qing Liu, Chunyu Jia, Yeh-Jun Lim, Guoqin Feng, Enquan Xu, Houfang Long, Yasuyoshi Kimura, Youqi Tao, Chunyu Zhao, Chuchu Wang, Zhenying Liu, Jin-Jian Hu, Meng-Rong Ma, Zhijun Liu, Lin Jiang, Dan Li, Ren-Xiao Wang, Valina L Dawson, Ted M Dawson, Yan-Mei Li, Xiaobo Mao, Cong Liu
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 118 (26) (2021)
Houfang Long, Weitong Zheng, Yang Liu, Yunpeng Sun, Kun Zhao, Zhenying Liu, Wencheng Xia, Shiran Lv, Zhengtao Liu, Dan Li, Kai-Wen He, Cong Liu
Wild-type α-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding. Proceedings of the National Academy of Sciences of the United States of America 118 (20) (2021)
Yunpeng Sun, Houfang Long, Wencheng Xia, Kun Wang, Xia Zhang, Bo Sun, Qin Cao, Yao-Yang Zhang, Bin Dai, Dan Li, Cong Liu
The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type α-synuclein. Nature communications 12 (1) (2021)
Dan Li, Cong Liu
Hierarchical chemical determination of amyloid polymorphs in neurodegenerative disease. Nature chemical biology 17 (3) (2021)
Li-Qiang Wang, Kun Zhao, Han-Ye Yuan, Xiang-Ning Li, Hai-Bin Dang, Yeyang Ma, Qiang Wang, Chen Wang, Yunpeng Sun, Jie Chen, Dan Li, Delin Zhang, Ping Yin, Cong Liu, Yi Yang
Genetic prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM. Science advances 7 (37) (2021)
Xialian Wu, Yeyang Ma, Kun Zhao, Jing Zhang, Yunpeng Sun, Yichen Li, Xingqi Dong, Hong Hu, Jing Liu, Jian Wang, Xia Zhang, Bing Li, Huayi Wang, Dan Li, Bo Sun, Jun-Xia Lu, Cong Liu
The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3. Proceedings of the National Academy of Sciences of the United States of America 118 (14) (2021)
Yunpeng Sun, Kun Zhao, Wencheng Xia, Guoqin Feng, Jinge Gu, Yeyang Ma, Xinrui Gui, Xia Zhang, Yanshan Fang, Bo Sun, Renxiao Wang, Cong Liu, Dan Li
The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure. Nature communications 11 (1) (2020)
Kun Zhao, Yeh-Jun Lim, Zhenying Liu, Houfang Long, Yunpeng Sun, Jin-Jian Hu, Chunyu Zhao, Youqi Tao, Xing Zhang, Dan Li, Yan-Mei Li, Cong Liu
Parkinson's disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 117 (33) (2020)
Kun Zhao, Yaowang Li, Zhenying Liu, Houfang Long, Chunyu Zhao, Feng Luo, Yunpeng Sun, Youqi Tao, Xiao-Dong Su, Dan Li, Xueming Li, Cong Liu
Parkinson's disease associated mutation E46K of α-synuclein triggers the formation of a distinct fibril structure. Nature communications 11 (1) (2020)
Li-Qiang Wang, Kun Zhao, Han-Ye Yuan, Qiang Wang, Zeyuan Guan, Jing Tao, Xiang-Ning Li, Yunpeng Sun, Chuan-Wei Yi, Jie Chen, Dan Li, Delin Zhang, Ping Yin, Cong Liu, Yi Yang
Cryo-EM structure of an amyloid fibril formed by full-length human prion protein. Nature structural & molecular biology 27 (6) (2020)
Zhenying Liu, Shengnan Zhang, Jinge Gu, Yilun Tong, Yichen Li, Xinrui Gui, Houfang Long, Chuchu Wang, Chunyu Zhao, Jinxia Lu, Lin He, Ying Li, Zhijun Liu, Dan Li, Cong Liu
Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation. Nature structural & molecular biology 27 (4) (2020)
Xiaojuan Ma, Yi Zhu, Jinxia Lu, Jingfei Xie, Chong Li, Woo Shik Shin, Jiali Qiang, Jiaqi Liu, Shuai Dou, Yi Xiao, Chuchu Wang, Chunyu Jia, Houfang Long, Juntao Yang, Yanshan Fang, Lin Jiang, Yaoyang Zhang, Shengnan Zhang, Rong Grace Zhai, Cong Liu, Dan Li
Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau. eLife 9 (2020)
Jinge Gu, Zhenying Liu, Shengnan Zhang, Yichen Li, Wencheng Xia, Chen Wang, Huaijiang Xiang, Zhijun Liu, Li Tan, Yanshan Fang, Cong Liu, Dan Li
Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles. Proceedings of the National Academy of Sciences of the United States of America 117 (49) (2020)
Chuchu Wang, Jia Tu, Shengnan Zhang, Bin Cai, Zhenying Liu, Shouqiao Hou, Qinglu Zhong, Xiao Hu, Wenbin Liu, Guo-Hui Li, Zhijun Liu, Lin He, Jiajie Diao, Zheng-Jiang Zhu, Dan Li, Cong Liu
Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly. Nature communications 11 (1) (2020)
Xinrui Gui, Feng Luo, Yichen Li, Heng Zhou, Zhenheng Qin, Zhenying Liu, Jinge Gu, Muyun Xie, Kun Zhao, Bin Dai, Woo Shik Shin, Jianhua He, Lin He, Lin Jiang, Minglei Zhao, Bo Sun, Xueming Li, Cong Liu, Dan Li
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly. Nature communications 10 (1) (2019)
Feng Luo, Xinrui Gui, Heng Zhou, Jinge Gu, Yichen Li, Xiangyu Liu, Minglei Zhao, Dan Li, Xueming Li, Cong Liu
Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. Nature structural & molecular biology 25 (4) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Dan Li