Dean Sheppard

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Topics

Pulmonary Fibrosis

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science immunology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Marco De Giovanni, Vivasvan S Vykunta, Adi Biram, Kevin Y Chen, Hanna Taglinao, Jinping An, Dean Sheppard, Helena Paidassi, Jason G Cyster
Mast cells help organize the Peyer's patch niche for induction of IgA responses. Science immunology 9 (93) (2024)
Marco De Giovanni, Vivasvan S Vykunta, Adi Biram, Kevin Y Chen, Hanna Taglinao, Jinping An, Dean Sheppard, Helena Paidassi, Jason G Cyster
Mast cells help organize the Peyer's patch niche for induction of IgA responses. Science immunology 9 (93) (2024)
Uyen Ngo, Ying Shi, Prescott Woodruff, Kevan Shokat, William F DeGrado, Hyunil Jo, Dean Sheppard, Aparna B Sundaram
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Marco De Giovanni, Vivasvan S Vykunta, Adi Biram, Kevin Y Chen, Hanna Taglinao, Jinping An, Dean Sheppard, Helena Paidassi, Jason G Cyster
Mast cells help organize the Peyer's patch niche for induction of IgA responses. Science immunology 9 (93) (2024)
Tatsuya Tsukui, Paul J Wolters, Dean Sheppard
Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis. Nature 631 (8021) (2024)
Uyen Ngo, Ying Shi, Prescott Woodruff, Kevan Shokat, William F DeGrado, Hyunil Jo, Dean Sheppard, Aparna B Sundaram
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Uyen Ngo, Ying Shi, Prescott Woodruff, Kevan Shokat, William F DeGrado, Hyunil Jo, Dean Sheppard, Aparna B Sundaram
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Tatsuya Tsukui, Paul J Wolters, Dean Sheppard
Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis. Nature (2024)
Uyen Ngo, Ying Shi, Prescott Woodruff, Kevan Shokat, William F DeGrado, Hyunil Jo, Dean Sheppard, Aparna B Sundaram
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Tatsuya Tsukui, Paul J Wolters, Dean Sheppard
Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis. Nature (2024)
Tatsuya Tsukui, Paul J Wolters, Dean Sheppard
Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis. Nature 631 (8021) (2024)
Uyen Ngo, Ying Shi, Prescott Woodruff, Kevan Shokat, William F DeGrado, Hyunil Jo, Dean Sheppard, Aparna B Sundaram
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Marco De Giovanni, Vivasvan S Vykunta, Adi Biram, Kevin Y Chen, Hanna Taglinao, Jinping An, Dean Sheppard, Helena Paidassi, Jason G Cyster
Mast cells help organize the Peyer's patch niche for induction of IgA responses. Science immunology 9 (93) (2024)
Marco De Giovanni, Vivasvan S Vykunta, Adi Biram, Kevin Y Chen, Hanna Taglinao, Jinping An, Dean Sheppard, Helena Paidassi, Jason G Cyster
Mast cells help organize the Peyer's patch niche for induction of IgA responses. Science immunology 9 (93) (2024)
Uyen Ngo, Ying Shi, Prescott Woodruff, Kevan Shokat, William F DeGrado, Hyunil Jo, Dean Sheppard, Aparna B Sundaram
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Tatsuya Tsukui, Paul J Wolters, Dean Sheppard
Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis. Nature 631 (8021) (2024)
Uyen Ngo, Ying Shi, Prescott Woodruff, Kevan Shokat, William F DeGrado, Hyunil Jo, Dean Sheppard, Aparna B Sundaram
IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Milica Vukmirovic, Kambez H Benam, Jason J Rose, Scott Turner, Chelsea M Magin, David Lagares, Alan H Cohen, Naftali Kaminski, Jeremy Alexander Hirota, Toby M Maher, Melanie Königshoff, Rama K Mallampalli, Dean Sheppard, Robert Tarran, Richard H Gomer, Richard Marshall, Nicholas J Kenyon, David Morris, Silke Hobbie, S Vamsee Raju, Irina Petrache, Timothy Watkins, Rishav Kumar, Wilbur A Lam, Todd Sherer, Louise Hecker
Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena: An Official American Thoracic Society Report. Annals of the American Thoracic Society (2023)
Zhuoran Yin, Neta Rosenzweig, Kilian L Kleemann, Xiaoming Zhang, Wesley Brandão, Milica A Margeta, Caitlin Schroeder, Kisha N Sivanathan, Sebastian Silveira, Christian Gauthier, Dania Mallah, Kristen M Pitts, Ana Durao, Shawn Herron, Hannah Shorey, Yiran Cheng, Jen-Li Barry, Rajesh K Krishnan, Sam Wakelin, Jared Rhee, Anthony Yung, Michael Aronchik, Chao Wang, Nimansha Jain, Xin Bao, Emma Gerrits, Nieske Brouwer, Amy Anderson Deik, Daniel Geoffrey Tenen, Tsuneya Ikezu, Nicolás Santander Grez, Gabriel L McKinsey, Caroline Baufeld, Dean Sheppard, Susanne Krasemann, Roni Nowarski, Bart J L Eggen, Andrew T Chan, Rudolph E Tanzi, Charlotte Madore, Thomas D Arnold, David M Holtzman, Oleg Butovsky
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints. Nature immunology (2023)
Lisa Sikkema, Ciro Ramírez-Suástegui, Daniel C Strobl, Tessa E Gillett, Luke Zappia, Elo Madissoon, Nikolay S Markov, Laure-Emmanuelle Zaragosi, Yuge Ji, Meshal Ansari, Marie-Jeanne Arguel, Leonie Apperloo, Martin Banchero, Christophe Bécavin, Marijn Berg, Evgeny Chichelnitskiy, Mei-I Chung, Antoine Collin, Aurore C A Gay, Janine Gote-Schniering, Baharak Hooshiar Kashani, Kemal Inecik, Manu Jain, Theodore S Kapellos, Tessa M Kole, Sylvie Leroy, Christoph H Mayr, Amanda J Oliver, Michael von Papen, Lance Peter, Chase J Taylor, Thomas Walzthoeni, Chuan Xu, Linh T Bui, Carlo De Donno, Leander Dony, Alen Faiz, Minzhe Guo, Austin J Gutierrez, Lukas Heumos, Ni Huang, Ignacio L Ibarra, Nathan D Jackson, Preetish Kadur Lakshminarasimha Murthy, Mohammad Lotfollahi, Tracy Tabib, Carlos Talavera-López, Kyle J Travaglini, Anna Wilbrey-Clark, Kaylee B Worlock, Masahiro Yoshida, null null, Maarten van den Berge, Yohan Bosse, Tushar J Desai, Oliver Eickelberg, Naftali Kaminski, Mark A Krasnow, Robert A Lafyatis, Marko Z Nikolić, Joseph E Powell, Jayaraj Rajagopal, Mauricio Rojas, Orit Rozenblatt-Rosen, Max A Seibold, Dean Sheppard, Douglas P Shepherd, Don D Sin, Hidde J Haisma, Alexander M Tsankov, Jeffrey A Whitsett, Yan Xu, Nicholas E Banovich, Pascal Barbry, Elizabeth Thu Duong, Christine S Falk, Kerstin B Meyer, Jonathan A Kropski, Dana Pe'er, Herbert B Schiller, Purushothama Rao Tata, Joachim L Schultze, Sarah A Teichmann, Alexander V Misharin, Martijn C Nawijn, Malte Daniel Luecken, Fabian Joachim Theis
An integrated cell atlas of the lung in health and disease. Nature medicine (2023)
Nabora S Reyes, Maria Krasilnikov, Nancy C Allen, Jin Young Lee, Ben Hyams, Minqi Zhou, Supriya Ravishankar, Monica Cassandras, Chaoqun Wang, Imran S Khan, Peri R Matatia, Yoshikazu Johmura, Ari B Molofsky, Michael A Matthay, Makoto Nakanishi, Dean Sheppard, Judith Campisi, Tien Peng
Sentinel p16 INK4a+ cells in the basement membrane form a reparative niche in the lung. Science (New York, N.Y.) 378 (6616) (2022)
Sagar P Bapat, Caroline Whitty, Cody T Mowery, Yuqiong Liang, Arum Yoo, Zewen Jiang, Michael C Peters, Ling-Juan Zhang, Ian Vogel, Carmen Zhou, Vinh Q Nguyen, Zhongmei Li, Christina Chang, Wandi S Zhu, Annette T Hastie, Helen He, Xin Ren, Wenli Qiu, Sarah G Gayer, Chang Liu, Eun Jung Choi, Marlys S Fassett, Jarish N Cohen, Jamie L Sturgill, Laura E Crotty Alexander, Jae Myoung Suh, Christopher Liddle, Annette R Atkins, Ruth T Yu, Michael Downes, Sihao Liu, Barbara S Nikolajczyk, In-Kyu Lee, Emma Guttman-Yassky, Karl Mark Ansel, Prescott G Woodruff, John V Fahy, Dean Sheppard, Richard L Gallo, Chun Jimmie Ye, Ronald M Evans, Ye Zheng, Alexander Marson
Obesity alters pathology and treatment response in inflammatory disease. Nature 604 (7905) (2022)
Sarah Alsamman, Stephanie A Christenson, Amy Yu, Nadia M E Ayad, Meghan S Mooring, Joe M Segal, Jimmy Kuang-Hsien Hu, Johanna R Schaub, Steve S Ho, Vikram Rao, Megan M Marlow, Scott M Turner, Mai Sedki, Lorena Pantano, Sarani Ghoshal, Diego Dos Santos Ferreira, Hsiao-Yen Ma, Caroline C Duwaerts, Regina Espanol-Suner, Lan Wei, Benjamin Newcomb, Izolda Mileva, Daniel Canals, Yusuf A Hannun, Raymond T Chung, Aras N Mattis, Bryan C Fuchs, Andrew M Tager, Dean Yimlamai, Valerie M Weaver, Alan C Mullen, Dean Sheppard, Jennifer Y Chen
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice. Science translational medicine 12 (557) (2021)
Alexandra Lainé, Ossama Labiad, Héctor Hernández-Vargas, Sébastien This, Amélien Sanlaville, Sophie Léon, Stéphane Dalle, Dean Sheppard, Mark A Travis, Helena Paidassi, Julien C Marie
Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation. Nature communications 12 (1) (2021)
Vincent C Auyeung, Dean Sheppard
Stuck in a Moment: Does Abnormal Persistence of Epithelial Progenitors Drive Pulmonary Fibrosis? American journal of respiratory and critical care medicine 203 (6) (2021)
Zhe Zhang, Meirong Bai, Guilherme Oliveira Barbosa, Andrew Chen, Yuehua Wei, Shuo Luo, Xin Wang, Bingying Wang, Tatsuya Tsukui, Hao Li, Dean Sheppard, Thomas B Kornberg, Dengke K Ma
Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. Science advances 6 (7) (2020)
Monica Cassandras, Chaoqun Wang, Jaymin J Kathiriya, Tatsuya Tsukui, Peri R Matatia, Michael Matthay, Paul Wolters, Ari Molofsky, Dean Sheppard, Harold A Chapman, Tien Peng
Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nature cell biology 22 (11) (2020)
Tatsuya Tsukui, Kai-Hui Sun, Joseph B Wetter, John R Wilson-Kanamori, Lisa A Hazelwood, Neil Cowan Henderson, Taylor S Adams, Jonas Christian Schupp, Sergio D Poli, Ivan O Rosas, Naftali Kaminski, Michael A Matthay, Paul J Wolters, Dean Sheppard
Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nature communications 11 (1) (2020)
Katarzyna Bulek, Xing Chen, Vandy Parron, Aparna Sundaram, Tomasz Herjan, Suidong Ouyang, Caini Liu, Alana K Majors, Jarod Zepp, Ji Gao, Ashok Dongre, Malgorzata Bodaszewska-Lubas, Arnaud Echard, Mark Aronica, Julie A Carman, Stavros Garantziotis, Dean Sheppard, Xiaoxia Li
IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility. Journal of immunology (Baltimore, Md. : 1950) 202 (5) (2019)
Thomas D Arnold, Carlos O Lizama, Kelly M Cautivo, Nicolás Santander Grez, Lucia Lin, Haiyan Qiu, Eric J Huang, Chang Liu, Yoh-Suke Mukouyama, Louis F Reichardt, Ann C Zovein, Dean Sheppard
Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction. The Journal of experimental medicine 216 (4) (2019)
Javed Mohammed, Lalit K Beura, Aleh Bobr, Brian Astry, Brian Chicoine, Sakeen W Kashem, Nathan E Welty, Botond Z Igyártó, Sathi Wijeyesinghe, Emily A Thompson, Catherine Matte, Laurent Bartholin, Alesia Kaplan, Dean Sheppard, Alina G Bridges, Warren D Shlomchik, David Masopust, Daniel H Kaplan
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β. Nature immunology 17 (4) (2016)
Jeremy P McAleer, Nikki L H Nguyen, Kong Chen, Pawan Kumar, David M Ricks, Matthew Binnie, Rachel A Armentrout, Derek A Pociask, Aaron M Hein, Amy Yu, Amit Vikram, Kyle J Bibby, Yoshinori Umesaki, Amariliz Rivera, Dean Sheppard, Wenjun Ouyang, Lora V Hooper, Jay K Kolls
Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome. Journal of immunology (Baltimore, Md. : 1950) 197 (1) (2016)