Beat W Schäfer (Beat W Schafer, Beat Schäfer, B W Schäfer)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 55

Top Venues

Nature communications

Leukemia

Molecular cancer therapeutics

Blood cancer discovery

University Childrens Hospital

ETH (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Childrens Hospital May 01 2002

Switzerland

Scientific Department Head :: Oncology

University Childrens Hospital Jan 08 1989 - May 01 2002

Switzerland

Group leader :: Clinical Chemistry and Biochemistry

Stanford University School of Medicine Oct 01 1986 - Jul 31 1989

United States

Postdoc :: Pharmacology

Education History

ETH Oct 01 1977 - May 01 1986

Switzerland

PHD

Publications

Michaela Kotrová, Eva Froňková, Michael Svatoň, Daniela Drandi, Felix Schön, Patricia Hoogeveen, Jeremy Hancock, Aneta Skotnicova, Anke Schilhabel, Cornelia Eckert, Emmanuelle Clappier, Giovanni Cazzaniga, Beat W Schäfer, Jacques J M van Dongen, Matthias Ritgen, Christiane Pott, Vincent H J van der Velden, Jan Trka, Monika Brüggemann
The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category. Leukemia (2024)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models. Molecular cancer therapeutics 23 (4) (2024)
Marco Wachtel, Didier Surdez, Thomas G P Grünewald, Beat W Schäfer
Functional Classification of Fusion Proteins in Sarcoma. Cancers 16 (7) (2024)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models. Molecular cancer therapeutics 23 (4) (2024)
Michaela Kotrová, Eva Froňková, Michael Svatoň, Daniela Drandi, Felix Schön, Patricia Hoogeveen, Jeremy Hancock, Aneta Skotnicova, Anke Schilhabel, Cornelia Eckert, Emmanuelle Clappier, Giovanni Cazzaniga, Beat W Schäfer, Jacques J M van Dongen, Matthias Ritgen, Christiane Pott, Vincent H J van der Velden, Jan Trka, Monika Brüggemann
The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category. Leukemia 38 (7) (2024)
Vincent H J van der Velden, Isabel Dombrink, Julia Alten, Giovanni Cazzaniga, Emmanuelle Clappier, Daniela Drandi, Cornelia Eckert, Eva Froňková, Jeremy Hancock, Michaela Kotrová, Rebekka Kraemer, Mirkka Montonen, Heike Pfeifer, Christiane Pott, Thorsten Raff, Heiko Trautmann, Hélène Cavé, Beat W Schäfer, Jacques J M van Dongen, Jan Trka, Monika Brüggemann, null null
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines. Leukemia 38 (6) (2024)
Sara G Danielli, Jakob Wurth, Sarah Morice, Samanta Kisele, Didier Surdez, Olivier O Delattre, Peter Karl Bode, Marco Wachtel, Beat W Schäfer
Evaluation of the Role of AXL in Fusion-positive Pediatric Rhabdomyosarcoma Identifies the Small-molecule Inhibitor Bemcentinib (BGB324) as Potent Chemosensitizer. Molecular cancer therapeutics 23 (6) (2024)
Sara G Danielli, Jakob Wurth, Sarah Morice, Samanta Kisele, Didier Surdez, Olivier O Delattre, Peter Karl Bode, Marco Wachtel, Beat W Schäfer
Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer. Molecular cancer therapeutics (2024)
Michaela Kotrová, Eva Froňková, Michael Svatoň, Daniela Drandi, Felix Schön, Patricia Hoogeveen, Jeremy Hancock, Aneta Skotnicova, Anke Schilhabel, Cornelia Eckert, Emmanuelle Clappier, Giovanni Cazzaniga, Beat W Schäfer, Jacques J M van Dongen, Matthias Ritgen, Christiane Pott, Vincent H J van der Velden, Jan Trka, Monika Brüggemann
The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category. Leukemia 38 (7) (2024)
Michaela Kotrová, Eva Froňková, Michael Svatoň, Daniela Drandi, Felix Schön, Patricia Hoogeveen, Jeremy Hancock, Aneta Skotnicova, Anke Schilhabel, Cornelia Eckert, Emmanuelle Clappier, Giovanni Cazzaniga, Beat W Schäfer, Jacques J M van Dongen, Matthias Ritgen, Christiane Pott, Vincent H J van der Velden, Jan Trka, Monika Brüggemann
The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category. Leukemia 38 (7) (2024)
Sara G Danielli, Jakob Wurth, Sarah Morice, Samanta Kisele, Didier Surdez, Olivier O Delattre, Peter Karl Bode, Marco Wachtel, Beat W Schäfer
Evaluation of the Role of AXL in Fusion-positive Pediatric Rhabdomyosarcoma Identifies the Small-molecule Inhibitor Bemcentinib (BGB324) as Potent Chemosensitizer. Molecular cancer therapeutics 23 (6) (2024)
Sara G Danielli, Jakob Wurth, Sarah Morice, Samanta Kisele, Didier Surdez, Olivier O Delattre, Peter Karl Bode, Marco Wachtel, Beat W Schäfer
Evaluation of the Role of AXL in Fusion-positive Pediatric Rhabdomyosarcoma Identifies the Small-molecule Inhibitor Bemcentinib (BGB324) as Potent Chemosensitizer. Molecular cancer therapeutics 23 (6) (2024)
Sara G Danielli, Yun Wei, Michael A Dyer, Elizabeth A Stewart, Heather S Sheppard, Marco Wachtel, Beat W Schäfer, Anand G Patel, David M Langenau
Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma. Nature communications 15 (1) (2024)
Marco Wachtel, Didier Surdez, Thomas G P Grünewald, Beat W Schäfer
Functional Classification of Fusion Proteins in Sarcoma. Cancers 16 (7) (2024)
Sara G Danielli, Jakob Wurth, Sarah Morice, Samanta Kisele, Didier Surdez, Olivier O Delattre, Peter Karl Bode, Marco Wachtel, Beat W Schäfer
Evaluation of the Role of AXL in Fusion-positive Pediatric Rhabdomyosarcoma Identifies the Small-molecule Inhibitor Bemcentinib (BGB324) as Potent Chemosensitizer. Molecular cancer therapeutics 23 (6) (2024)
Vincent H J van der Velden, Isabel Dombrink, Julia Alten, Giovanni Cazzaniga, Emmanuelle Clappier, Daniela Drandi, Cornelia Eckert, Eva Froňková, Jeremy Hancock, Michaela Kotrová, Rebekka Kraemer, Mirkka Montonen, Heike Pfeifer, Christiane Pott, Thorsten Raff, Heiko Trautmann, Hélène Cavé, Beat W Schäfer, Jacques J M van Dongen, Jan Trka, Monika Brüggemann, null null
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines. Leukemia 38 (6) (2024)
Marco Wachtel, Didier Surdez, Thomas G P Grünewald, Beat W Schäfer
Functional Classification of Fusion Proteins in Sarcoma. Cancers 16 (7) (2024)
Vincent H J van der Velden, Isabel Dombrink, Julia Alten, Giovanni Cazzaniga, Emmanuelle Clappier, Daniela Drandi, Cornelia Eckert, Eva Froňková, Jeremy Hancock, Michaela Kotrová, Rebekka Kraemer, Mirkka Montonen, Heike Pfeifer, Christiane Pott, Thorsten Raff, Heiko Trautmann, Hélène Cavé, Beat W Schäfer, Jacques J M van Dongen, Jan Trka, Monika Brüggemann, null null
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines. Leukemia 38 (6) (2024)
Vincent H J van der Velden, Isabel Dombrink, Julia Alten, Giovanni Cazzaniga, Emmanuelle Clappier, Daniela Drandi, Cornelia Eckert, Eva Froňková, Jeremy Hancock, Michaela Kotrová, Rebekka Kraemer, Mirkka Montonen, Heike Pfeifer, Christiane Pott, Thorsten Raff, Heiko Trautmann, Hélène Cavé, Beat W Schäfer, Jacques J M van Dongen, Jan Trka, Monika Brüggemann, null null
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines. Leukemia (2024)
Sara G Danielli, Yun Wei, Michael A Dyer, Elizabeth A Stewart, Heather S Sheppard, Marco Wachtel, Beat W Schäfer, Anand G Patel, David M Langenau
Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma. Nature communications 15 (1) (2024)
Sara G Danielli, Yun Wei, Michael A Dyer, Elizabeth A Stewart, Heather S Sheppard, Marco Wachtel, Beat W Schäfer, Anand G Patel, David M Langenau
Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma. Nature communications 15 (1) (2024)
Vincent H J van der Velden, Isabel Dombrink, Julia Alten, Giovanni Cazzaniga, Emmanuelle Clappier, Daniela Drandi, Cornelia Eckert, Eva Froňková, Jeremy Hancock, Michaela Kotrová, Rebekka Kraemer, Mirkka Montonen, Heike Pfeifer, Christiane Pott, Thorsten Raff, Heiko Trautmann, Hélène Cavé, Beat W Schäfer, Jacques J M van Dongen, Jan Trka, Monika Brüggemann, null null
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines. Leukemia 38 (6) (2024)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models. Molecular cancer therapeutics 23 (4) (2024)
Michaela Kotrová, Eva Froňková, Michael Svatoň, Daniela Drandi, Felix Schön, Patricia Hoogeveen, Jeremy Hancock, Aneta Skotnicova, Anke Schilhabel, Cornelia Eckert, Emmanuelle Clappier, Giovanni Cazzaniga, Beat W Schäfer, Jacques J M van Dongen, Matthias Ritgen, Christiane Pott, Vincent H J van der Velden, Jan Trka, Monika Brüggemann
The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category. Leukemia 38 (7) (2024)
Rathana Kim, Hugo Bergugnat, Lise Larcher, Matthieu Duchmann, Marie Passet, Stéphanie Gachet, Wendy Cuccuini, Marina Lafage-Pochitaloff, Cédric Pastoret, Nathalie Grardel, Vahid Asnafi, Beat W Schäfer, Eric Delabesse, Raphaël A Itzykson, Lionel Ades, Yosr Hicheri, Yves Chalandon, Carlos Graux, Patrice Chevallier, Mathilde M Hunault-Berger, Thibaut Tl Leguay, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Jean Soulier, Philippe Rousselot, Nicolas Boissel, Emmanuelle Clappier
Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis. Blood cancer discovery 4 (2) (2023)
Yaw Asante, Katharina Benischke, Issra Osman, Quy A Ngo, Jakob Wurth, Dominik Laubscher, Hyun Min Kim, Bhavatharini Udhayakumar, Md Imdadul H Khan, Diana H Chin, Jadon Porch, Maharshi Chakraborty, Richard Sallari, Olivier O Delattre, Sakina Zaidi, Sarah Morice, Didier Surdez, Sara G Danielli, Beat W Schäfer, Berkley E Gryder, Marco Wachtel
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution. Nature communications 14 (1) (2023)
Rathana Kim, Hugo Bergugnat, Lise Larcher, Matthieu Duchmann, Marie Passet, Stéphanie Gachet, Wendy Cuccuini, Marina Lafage-Pochitaloff, Cédric Pastoret, Nathalie Grardel, Vahid Asnafi, Beat W Schäfer, Eric Delabesse, Raphaël A Itzykson, Lionel Ades, Yosr Hicheri, Yves Chalandon, Carlos Graux, Patrice Chevallier, Mathilde M Hunault-Berger, Thibaut Tl Leguay, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Jean Soulier, Philippe Rousselot, Nicolas Boissel, Emmanuelle Clappier
Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis. Blood cancer discovery 4 (2) (2023)
Silvia Pomella, Matteo Cassandri, Lucrezia D'Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R Vakoc, Enrico Velardi, Beat W Schäfer, Ernesto Guccione, Susanne Andrea Gatz, Ajla Wasti, Marielle Yohe, Myron S Ignatius, Concetta Quintarelli, Janet M Shipley, Lucio Miele, Javed Khan, Peter J Houghton, Francesco Marampon, Berkley E Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57 Kip2 targeting. Nature communications 14 (1) (2023)
Rathana Kim, Hugo Bergugnat, Lise Larcher, Matthieu Duchmann, Marie Passet, Stéphanie Gachet, Wendy Cuccuini, Marina Lafage-Pochitaloff, Cédric Pastoret, Nathalie Grardel, Vahid Asnafi, Beat W Schäfer, Eric Delabesse, Raphaël A Itzykson, Lionel Ades, Yosr Hicheri, Yves Chalandon, Carlos Graux, Patrice Chevallier, Mathilde M Hunault-Berger, Thibaut Tl Leguay, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Jean Soulier, Philippe Rousselot, Nicolas Boissel, Emmanuelle Clappier
Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis. Blood cancer discovery 4 (2) (2023)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has anti-tumor activity in preclinical patient-derived pediatric solid tumor models. Molecular cancer therapeutics (2023)
Yaw Asante, Katharina Benischke, Issra Osman, Quy A Ngo, Jakob Wurth, Dominik Laubscher, Hyun Min Kim, Bhavatharini Udhayakumar, Md Imdadul H Khan, Diana H Chin, Jadon Porch, Maharshi Chakraborty, Richard Sallari, Olivier O Delattre, Sakina Zaidi, Sarah Morice, Didier Surdez, Sara G Danielli, Beat W Schäfer, Berkley E Gryder, Marco Wachtel
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution. Nature communications 14 (1) (2023)
C Meyer, P Larghero, Bruno A Lopes, Thomas Burmeister, D Gröger, Rosemary Sutton, N C Venn, G Cazzaniga, L Corral Abascal, G Tsaur, L Fechina, Mariana Emerenciano, Maria S Pombo-de-Oliveira, T Lund-Aho, T Lundán, M Montonen, V Juvonen, Jan Zuna, J Trka, P Ballerini, H Lapillonne, Vincent H J van der Velden, E Sonneveld, E Delabesse, Roberto R Capela de Matos, Maria Luiza Macedo Silva, Simon Bomken, K Katsibardi, M Keernik, N Grardel, J Mason, R Price, J Kim, C Eckert, L Lo Nigro, C Bueno, P Menendez, U Zur Stadt, P Gameiro, L Sedék, T Szczepański, Audrey Bidet, V Marcu, K Shichrur, S Izraeli, H O Madsen, Beat W Schäfer, S Kubetzko, Rathana Kim, E Clappier, Heiko Trautmann, M Brüggemann, P Archer, J Hancock, J Alten, A Möricke, Martin Stanulla, J Lentes, A K Bergmann, Sabine Strehl, S Köhrer, K Nebral, M N Dworzak, Oskar A Haas, C Arfeuille, Aurélie Caye-Eude, Hélène Cave, Rolf Marschalek
The KMT2A recombinome of acute leukemias in 2023. Leukemia (2023)
Joana G Marques, Blaz Pavlovic, Quy A Ngo, Gloria Pedot, Michaela Roemmele, Larissa Volken, Samanta Kisele, Romain Perbet, Marco Wachtel, Beat W Schäfer
The chromatin remodeler CHD4 sustains Ewing Sarcoma cell survival by controlling global chromatin architecture. Cancer research (2023)
Sara G Danielli, Ermelinda Porpiglia, Andrea J De Micheli, Natalia Navarro, Michael J Zellinger, Ingrid Bechtold, Samanta Kisele, Larissa Volken, Joana G Marques, Stephanie Kasper, Peter Karl Bode, Anton G Henssen, Dennis Gurgen, Olivier Delattre, Didier Surdez, Josep Roma, Peter Bühlmann, Helen M Blau, Marco Wachtel, Beat W Schäfer
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. Science advances 9 (6) (2023)
Sara G Danielli, Ermelinda Porpiglia, Andrea J De Micheli, Natalia Navarro, Michael J Zellinger, Ingrid Bechtold, Samanta Kisele, Larissa Volken, Joana G Marques, Stephanie Kasper, Peter Karl Bode, Anton G Henssen, Dennis Gurgen, Olivier Delattre, Didier Surdez, Josep Roma, Peter Bühlmann, Helen M Blau, Marco Wachtel, Beat W Schäfer
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. Science advances 9 (6) (2023)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has anti-tumor activity in preclinical patient-derived pediatric solid tumor models. Molecular cancer therapeutics (2023)
Rathana Kim, Hugo Bergugnat, Lise Larcher, Matthieu Duchmann, Marie Passet, Stéphanie Gachet, Wendy Cuccuini, Marina Lafage-Pochitaloff, Cédric Pastoret, Nathalie Grardel, Vahid Asnafi, Beat W Schäfer, Eric Delabesse, Raphaël A Itzykson, Lionel Ades, Yosr Hicheri, Yves Chalandon, Carlos Graux, Patrice Chevallier, Mathilde M Hunault-Berger, Thibaut Tl Leguay, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Jean Soulier, Philippe Rousselot, Nicolas Boissel, Emmanuelle Clappier
Adult low hypodiploid acute lymphoblastic leukemia emerges from pre-leukemic TP53-mutant clonal hematopoiesis. Blood cancer discovery (2023)
Sara G Danielli, Ermelinda Porpiglia, Andrea J De Micheli, Natalia Navarro, Michael J Zellinger, Ingrid Bechtold, Samanta Kisele, Larissa Volken, Joana G Marques, Stephanie Kasper, Peter Karl Bode, Anton G Henssen, Dennis Gurgen, Olivier Delattre, Didier Surdez, Josep Roma, Peter Bühlmann, Helen M Blau, Marco Wachtel, Beat W Schäfer
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. Science advances 9 (6) (2023)
Rathana Kim, Hugo Bergugnat, Lise Larcher, Matthieu Duchmann, Marie Passet, Stéphanie Gachet, Wendy Cuccuini, Marina Lafage-Pochitaloff, Cédric Pastoret, Nathalie Grardel, Vahid Asnafi, Beat W Schäfer, Eric Delabesse, Raphaël A Itzykson, Lionel Ades, Yosr Hicheri, Yves Chalandon, Carlos Graux, Patrice Chevallier, Mathilde M Hunault-Berger, Thibaut Tl Leguay, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Jean Soulier, Philippe Rousselot, Nicolas Boissel, Emmanuelle Clappier
Adult low hypodiploid acute lymphoblastic leukemia emerges from pre-leukemic TP53-mutant clonal hematopoiesis. Blood cancer discovery (2023)
Silvia Pomella, Matteo Cassandri, Lucrezia D'Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R Vakoc, Enrico Velardi, Beat W Schäfer, Ernesto Guccione, Susanne Andrea Gatz, Ajla Wasti, Marielle Yohe, Myron S Ignatius, Concetta Quintarelli, Janet M Shipley, Lucio Miele, Javed Khan, Peter J Houghton, Francesco Marampon, Berkley E Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57 Kip2 targeting. Nature communications 14 (1) (2023)
Silvia Pomella, Matteo Cassandri, Lucrezia D'Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R Vakoc, Enrico Velardi, Beat W Schäfer, Ernesto Guccione, Susanne Andrea Gatz, Ajla Wasti, Marielle Yohe, Myron S Ignatius, Concetta Quintarelli, Janet M Shipley, Lucio Miele, Javed Khan, Peter J Houghton, Francesco Marampon, Berkley E Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57 Kip2 targeting. Nature communications 14 (1) (2023)
Silvia Pomella, Sara G Danielli, Rita Alaggio, Willemijn B Breunis, Ebrahem Hamed, Joanna Selfe, Marco Wachtel, Zoe S Walters, Beat W Schäfer, Rossella Rota, Janet M Shipley, Simone Hettmer
Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma. Cancers 15 (10) (2023)
Sara G Danielli, Ermelinda Porpiglia, Andrea J De Micheli, Natalia Navarro, Michael J Zellinger, Ingrid Bechtold, Samanta Kisele, Larissa Volken, Joana G Marques, Stephanie Kasper, Peter Karl Bode, Anton G Henssen, Dennis Gurgen, Olivier Delattre, Didier Surdez, Josep Roma, Peter Bühlmann, Helen M Blau, Marco Wachtel, Beat W Schäfer
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. Science advances 9 (6) (2023)
Silvia Pomella, Matteo Cassandri, Lucrezia D'Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R Vakoc, Enrico Velardi, Beat W Schäfer, Ernesto Guccione, Susanne Andrea Gatz, Ajla Wasti, Marielle Yohe, Myron S Ignatius, Concetta Quintarelli, Janet M Shipley, Lucio Miele, Javed Khan, Peter J Houghton, Francesco Marampon, Berkley E Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57 Kip2 targeting. Nature communications 14 (1) (2023)
Yaw Asante, Katharina Benischke, Issra Osman, Quy A Ngo, Jakob Wurth, Dominik Laubscher, Hyun Min Kim, Bhavatharini Udhayakumar, Md Imdadul H Khan, Diana H Chin, Jadon Porch, Maharshi Chakraborty, Richard Sallari, Olivier O Delattre, Sakina Zaidi, Sarah Morice, Didier Surdez, Sara G Danielli, Beat W Schäfer, Berkley E Gryder, Marco Wachtel
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution. Nature communications 14 (1) (2023)
Dominik Laubscher, Berkley E Gryder, Benjamin D Sunkel, Thorkell Andresson, Marco Wachtel, Sudipto Das, Bernd Roschitzki, Witold Wolski, Xiaoli S Wu, Hsien-Chao Chou, Young K Song, Chaoyu Wang, Jun S Wei, Meng Wang, Xinyu Wen, Quy Ai Ngo, Joana G Marques, Christopher R Vakoc, Beat W Schäfer, Benjamin Z Stanton, Javed Khan
BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma. Nature communications 12 (1) (2021)
Tamara Kazimova, Fabienne Tschanz, Ashish Sharma, Irma Telarovic, Marco Wachtel, Gloria Pedot, Beat W Schäfer, Martin Pruschy
Paracrine Placental Growth Factor Signaling in Response to Ionizing Radiation Is p53-Dependent and Contributes to Radioresistance. Molecular cancer research : MCR 19 (6) (2021)
Lisa Bierbaumer, Anna M Katschnig, Branka Radic-Sarikas, Maximilian O Kauer, Jeffrey A Petro, Sandra Högler, Elisabeth Gurnhofer, Gloria Pedot, Beat W Schäfer, Raphaela Schwentner, Karin Mühlbacher, Florian Kromp, Dave N T Aryee, Lukas Kenner, Aykut Uren, Heinrich Kovar
YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells. Oncogenesis 10 (1) (2021)
Melanie Generali, Sampoorna Satheesha, Peter K Bode, Debora Wanner, Beat W Schäfer, Elisa A Casanova
High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma. Genes 12 (9) (2021)
Eva Brack, Marco Wachtel, Anja Wolf, Andres Kaech, Urs Ziegler, Beat W Schäfer
Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma. Cell death and differentiation 27 (8) (2020)
Joana G Marques, Berkley E Gryder, Blaz Pavlovic, Yeonjoo Chung, Quy A Ngo, Fabian Frommelt, Matthias Gstaiger, Young Song, Katharina Benischke, Dominik Laubscher, Marco Wachtel, Javed Khan, Beat W Schäfer
NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency. eLife 9 (2020)
Gabriele Manzella, Leonie D Schreck, Willemijn B Breunis, Jan Molenaar, Hans Merks, Frederic G Barr, Wenyue Sun, Michaela Römmele, Luduo Zhang, Joelle Tchinda, Quy A Ngo, Peter Karl Bode, Olivier O Delattre, Didier Surdez, Bharat Rekhi, Felix K Niggli, Beat W Schäfer, Marco Wachtel
Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity. Nature communications 11 (1) (2020)
David O Azorsa, Peter Karl Bode, Marco Wachtel, Adam Tai Chi Cheuk, Paul S Meltzer, Christian Vokuhl, Ulrike Camenisch, Huy Leng Khov, Beata Bode, Beat W Schäfer, Javed Khan
Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 34 (4) (2020)
Nagjie Alijaj, Sandrine Moutel, Zelia L Gouveia, Maxim Gray, Maurizio Roveri, Dzhangar Dzhumashev, Florian Weber, Gianmarco Meier, Paola Luciani, Jochen K Rössler, Beat W Schäfer, Franck Perez, Michele Bernasconi
Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma. Cancers 12 (11) (2020)
Maria E Gierisch, Gloria Pedot, Franziska Walser, Laura A Lopez-Garcia, Patricia Jaaks, Felix K Niggli, Beat W Schäfer
USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth. Scientific reports 9 (1) (2019)

Beat W Schäfer (Beat W Schafer, Beat Schäfer, B W Schäfer)

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