David M Langenau (D M Langenau)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 19

Top Topics

Transcription Factor

Cancer Stem Cells

Top Venues

The Journal of experimental medicine

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Sara G Danielli, Yun Wei, Michael A Dyer, Elizabeth A Stewart, Heather S Sheppard, Marco Wachtel, Beat W Schäfer, Anand G Patel, David M Langenau
Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma. Nature communications 15 (1) (2024)
Sara G Danielli, Yun Wei, Michael A Dyer, Elizabeth A Stewart, Heather S Sheppard, Marco Wachtel, Beat W Schäfer, Anand G Patel, David M Langenau
Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma. Nature communications 15 (1) (2024)
Sara G Danielli, Yun Wei, Michael A Dyer, Elizabeth A Stewart, Heather S Sheppard, Marco Wachtel, Beat W Schäfer, Anand G Patel, David M Langenau
Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma. Nature communications 15 (1) (2024)
Luciana Da Silveira Cavalcante, Manuela Lopera Higuita, Juan Manuel González-Rosa, Beatriz Marques, Samantha To, Casie A Pendexter, Stephanie E J Cronin, Kaustav A Gopinathan, Reinier J De Vries, Felix Ellett, Korkut Uygun, David M Langenau, Mehmet Toner, Shannon N Tessier
Zebrafish as a high throughput model for organ preservation and transplantation research. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37 (10) (2023)
Yun Wei, Qian Qin, Chuan Yan, Madeline N Hayes, Sara P Garcia, Haibin Xi, Daniel Do, Alexander H Jin, Tiffany C Eng, Karin M McCarthy, Abhinav Adhikari, Maristela L Onozato, Dimitrios Spentzos, Gunnlaugur P Neilsen, A John Iafrate, Leonard H Wexler, April D Pyle, Mario L Suvà, Filemon Dela Cruz, Luca Pinello, David M Langenau
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma. Nature cancer 3 (8) (2022)
Maja Solman, Sasja Blokzijl-Franke, Florian Piques, Chuan Yan, Qiqi Yang, Marion Strullu, Sarah M Kamel, Pakize Ak, Jeroen Bakkers, David M Langenau, Hélène Cave, Jeroen den Hertog
Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects. eLife 11 (2022)
Saara Laukkanen, Alexandra Veloso, Chuan Yan, Laura Oksa, Eric J Alpert, Daniel Do, Noora Hyvärinen, Karin McCarthy, Abhinav Adhikari, Qiqi Yang, Sowmya Iyer, Sara P Garcia, Annukka Pello, Tanja Ruokoranta, Sanni Moisio, Sadiksha Adhikari, Jeffrey A Yoder, Kayleigh Gallagher, Lauren Whelton, James R Allen, Alexander H Jin, Siebe Loontiens, Merja Heinäniemi, Michelle Kelliher, Caroline A Heckman, Olli Lohi, David M Langenau
Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia. Blood 140 (17) (2022)
E Elizabeth Patton, Leonard I Zon, David M Langenau
Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials. Nature reviews. Drug discovery 20 (8) (2021)
Chuan Yan, Qiqi Yang, Songfa Zhang, David G Millar, Eric J Alpert, Daniel Do, Alexandra Veloso, Dalton C Brunson, Benjamin J Drapkin, Marcello Stanzione, Irene Scarfo, John C Moore, Sowmya Iyer, Qian Qin, Yun Wei, Karin M McCarthy, John F Rawls, Nicholas J Dyson, Mark Cobbold, Marcela V Maus, David M Langenau
Single-cell imaging of T cell immunotherapy responses in vivo. The Journal of experimental medicine 218 (10) (2021)
Maurizio Fazio, Julien Ablain, Chuan Yan, David M Langenau, Leonard I Zon
Zebrafish patient avatars in cancer biology and precision cancer therapy. Nature reviews. Cancer 20 (5) (2020)
Chuan Yan, Daniel Do, Qiqi Yang, Dalton C Brunson, John F Rawls, David M Langenau
Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish. Nature protocols 15 (9) (2020)
Siebe Loontiens, Suzanne Vanhauwaert, Lisa Depestel, Givani Dewyn, Wouter Van Loocke, Finola E Moore, Elaine G Garcia, Lance Batchelor, Chiara Borga, Barbara Squiban, Megan Malone-Perez, Pieter-Jan Volders, Volodimir Olexiouk, Pieter Van Vlierberghe, David M Langenau, J Kimble Frazer, Kaat Durink, Frank Speleman
A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models. Leukemia 34 (12) (2020)
E G Garcia, Alexandra Veloso, M L Oliveira, James R Allen, Siebe Loontiens, D Brunson, D Do, Chuan Yan, R Morris, S Iyer, Sara P Garcia, N Iftimia, W Van Loocke, F Matthijssens, K McCarthy, Joao T Barata, Frank Speleman, Tom Taghon, Alejandro Gutierrez, Pieter Van Vlierberghe, W Haas, J S Blackburn, David M Langenau
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis. Leukemia 35 (3) (2020)
Myron S Ignatius, Madeline N Hayes, Finola E Moore, Qin Tang, Sara P Garcia, Patrick R Blackburn, Kunal Baxi, Long Wang, Alexander Jin, Ashwin Ramakrishnan, Sophia Reeder, Yidong Chen, Gunnlaugur Petur Nielsen, Eleanor Y Chen, Robert P Hasserjian, Franck Tirode, Stephen C Ekker, David M Langenau
tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish. eLife 7 (2018)
Marc R Mansour, Shuning He, Zhaodong Li, Riadh Lobbardi, Brian J Abraham, Clemens Hug, Sunniyat Rahman, Theresa E León, You-Yi Kuang, Mark W Zimmerman, Traci M Blonquist, Evisa Gjini, Alejandro Gutierrez, Qin Tang, Laura Garcia-Perez, Karin Pike-Overzet, Lars Anders, Alla Berezovskaya, Yi Zhou, Leonard I Zon, Donna S Neuberg, Adele K Fielding, Frank J T Staal, David M Langenau, Takaomi Sanda, Richard A Young, A Thomas Look
JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. The Journal of experimental medicine 215 (7) (2018)
Melissa Kasheta, Corrie A Painter, Finola E Moore, Riadh Lobbardi, Alysia Bryll, Eli Freiman, David Stachura, Arlin B Rogers, Yariv Houvras, David M Langenau, Yvonne J K Edwards
Identification and characterization of T reg-like cells in zebrafish. The Journal of experimental medicine 214 (12) (2017)
Qin Tang, Sowmya Iyer, Riadh Lobbardi, John C Moore, Huidong Chen, Caleb A Lareau, Christine Hebert, McKenzie L Shaw, Cyril Neftel, Mario L Suva, Yvonne J K Edwards, Andre Bernards, Martin Aryee, Luca Pinello, Iain A Drummond, David M Langenau
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing. The Journal of experimental medicine 214 (10) (2017)
Inês M Tenente, Madeline N Hayes, Myron S Ignatius, Karin McCarthy, Marielle Yohe, Sivasish Sindiri, Berkley Gryder, Mariana L Oliveira, Ashwin Ramakrishnan, Qin Tang, Eleanor Y Chen, G Petur Nielsen, Javed Khan, David M Langenau
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma. eLife 6 (2017)
John C Moore, Qin Tang, Nora Torres Yordán, Finola E Moore, Elaine G Garcia, Riadh Lobbardi, Ashwin Ramakrishnan, Dieuwke L Marvin, Anthony Anselmo, Ruslan I Sadreyev, David M Langenau
Single-cell imaging of normal and malignant cell engraftment into optically clear prkdc-null SCID zebrafish. The Journal of experimental medicine 213 (12) (2016)