Benjamin J Hackel

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 64

Top Topics

Epidermal Growth Factor Receptor

Listeria Monocytogenes

Duchenne Muscular Dystrophy

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Protein engineering, design & selection : PEDS

ACS synthetic biology

ACS chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Manjie Huang, Marina Rueda-Garcia, Abbigael Harthorn, Benjamin J Hackel, James A Van Deventer
Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface. ACS chemical biology 19 (2) (2024)
Gregory H Nielsen, Zachary D Schmitz, Benjamin J Hackel
Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization. Protein engineering, design & selection : PEDS 37 (2024)
Jonathan Collins, Benjamin J Hackel
Sequence-activity mapping via depletion reveals striking mutational tolerance and elucidates functional motifs in Tur1a antimicrobial peptide. Protein engineering, design & selection : PEDS (2024)
Gregory H Nielsen, Zachary D Schmitz, Benjamin J Hackel
Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization. Protein engineering, design & selection : PEDS 37 (2024)
Manjie Huang, Marina Rueda-Garcia, Abbigael Harthorn, Benjamin J Hackel, James A Van Deventer
Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface. ACS chemical biology 19 (2) (2024)
Gregory H Nielsen, Zachary D Schmitz, Benjamin J Hackel
Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization. Protein engineering, design & selection : PEDS 37 (2024)
Manjie Huang, Marina Rueda-Garcia, Abbigael Harthorn, Benjamin J Hackel, James A Van Deventer
Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface. ACS chemical biology 19 (2) (2024)
Manjie Huang, Marina Rueda-Garcia, Abbigael Harthorn, Benjamin J Hackel, James A Van Deventer
Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface. ACS chemical biology (2024)
Manjie Huang, Marina Rueda-Garcia, Abbigael Harthorn, Benjamin J Hackel, James A Van Deventer
Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface. ACS chemical biology 19 (2) (2024)
Jonathan Collins, Benjamin J Hackel
Sequence-activity mapping via depletion reveals striking mutational tolerance and elucidates functional motifs in Tur1a antimicrobial peptide. Protein engineering, design & selection : PEDS 37 (2024)
Jonathan Collins, Benjamin J Hackel
Sequence-activity mapping via depletion reveals striking mutational tolerance and elucidates functional motifs in Tur1a antimicrobial peptide. Protein engineering, design & selection : PEDS 37 (2024)
Manjie Huang, Marina Rueda-Garcia, Abbigael Harthorn, Benjamin J Hackel, James A Van Deventer
Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface. ACS chemical biology 19 (2) (2024)
Gregory H Nielsen, Zachary D Schmitz, Benjamin J Hackel
Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization. Protein engineering, design & selection : PEDS (2024)
Gregory H Nielsen, Zachary D Schmitz, Benjamin J Hackel
Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization. Protein engineering, design & selection : PEDS 37 (2024)
Paul L Blanchard, Brandon J Knick, Sarah A Whelan, Benjamin J Hackel
Hyperstable Synthetic Mini-Proteins as Effective Ligand Scaffolds. ACS synthetic biology (2023)
Alexander W Golinski, Zachary D Schmitz, Gregory H Nielsen, Bryce Johnson, Diya Saha, Sandhya Appiah, Benjamin J Hackel, Stefano Martiniani
Predicting and Interpreting Protein Developability Via Transfer of Convolutional Sequence Representation. ACS synthetic biology (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Daniel T Tresnak, Benjamin J Hackel
Deep Antimicrobial Activity and Stability Analysis Inform Lysin Sequence-Function Mapping. ACS synthetic biology (2023)
Daniel T Tresnak, Benjamin J Hackel
Deep Antimicrobial Activity and Stability Analysis Inform Lysin Sequence-Function Mapping. ACS synthetic biology 12 (1) (2023)
Daniel T Tresnak, Benjamin J Hackel
Deep Antimicrobial Activity and Stability Analysis Inform Lysin Sequence-Function Mapping. ACS synthetic biology 12 (1) (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Joseph F Hassler, Megan Lawson, Erika Cerna Arroyo, Frank S Bates, Benjamin J Hackel, Timothy P Lodge
Discovery of Kinetic Trapping of Poloxamers inside Liposomes via Thermal Treatment. Langmuir : the ACS journal of surfaces and colloids (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Nagamani Vunnam, MaryJane Been, Evan Huber, Carolyn N Paulson, Sophia Szymonski, Benjamin J Hackel, Jonathan N Sachs
Discovery of a Non-competitive TNFR1 Antagonist Affibody with Picomolar Monovalent Potency That Does Not Affect TNFR2 Function. Molecular pharmaceutics (2023)
Daniel T Tresnak, Benjamin J Hackel
Deep Antimicrobial Activity and Stability Analysis Inform Lysin Sequence-Function Mapping. ACS synthetic biology 12 (1) (2023)
Adelyn A Crabtree, Natalie Boehnke, Frank S Bates, Benjamin J Hackel
Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Joseph F Hassler, Adelyn Crabtree, Lucy Liberman, Frank S Bates, Benjamin J Hackel, Timothy P Lodge
Effect of Bottlebrush Poloxamer Architecture on Binding to Liposomes. Biomacromolecules 24 (1) (2022)
Joseph F Hassler, Adelyn Crabtree, Lucy Liberman, Frank S Bates, Benjamin J Hackel, Timothy P Lodge
Effect of Bottlebrush Poloxamer Architecture on Binding to Liposomes. Biomacromolecules 24 (1) (2022)
Joseph F Hassler, Nicholas J Van Zee, Adelyn A Crabtree, Frank S Bates, Benjamin J Hackel, Timothy P Lodge
Synthesis and Micellization of Bottlebrush Poloxamers. ACS macro letters 11 (4) (2022)
Joseph F Hassler, Adelyn Crabtree, Lucy Liberman, Frank S Bates, Benjamin J Hackel, Timothy P Lodge
Effect of Bottlebrush Poloxamer Architecture on Binding to Liposomes. Biomacromolecules 24 (1) (2022)
Joseph F Hassler, Adelyn Crabtree, Lucy Liberman, Frank S Bates, Benjamin J Hackel, Timothy P Lodge
Effect of Bottlebrush Poloxamer Architecture on Binding to Liposomes. Biomacromolecules (2022)
Alexander W Golinski, Katelynn M Mischler, Sidharth Laxminarayan, Nicole L Neurock, Matthew Fossing, Hannah Pichman, Stefano Martiniani, Benjamin J Hackel
High-throughput developability assays enable library-scale identification of producible protein scaffold variants. Proceedings of the National Academy of Sciences of the United States of America 118 (23) (2021)
Matthew P DeJong, Seth C Ritter, Katharina A Fransen, Daniel T Tresnak, Alexander W Golinski, Benjamin J Hackel
A Platform for Deep Sequence-Activity Mapping and Engineering Antimicrobial Peptides. ACS synthetic biology 10 (10) (2021)
Mihee Kim, Frank Heinrich, Greg Haugstad, Guichuan Yu, Guangcui Yuan, Sushil K Satija, Wenjia Zhang, Hannah S Seo, Joseph M Metzger, Samira M Azarin, Timothy P Lodge, Benjamin J Hackel, Frank S Bates
Spatial Distribution of PEO-PPO-PEO Block Copolymer and PEO Homopolymer in Lipid Bilayers. Langmuir : the ACS journal of surfaces and colloids 36 (13) (2020)
Wenjia Zhang, Joseph M Metzger, Benjamin J Hackel, Frank S Bates, Timothy P Lodge
Influence of the Headgroup on the Interaction of Poly(ethylene oxide)-Poly(propylene oxide) Block Copolymers with Lipid Bilayers. The journal of physical chemistry. B 124 (12) (2020)
Daniel T Tresnak, Benjamin J Hackel
Mining and Statistical Modeling of Natural and Variant Class IIa Bacteriocins Elucidate Activity and Selectivity Profiles across Species. Applied and environmental microbiology 86 (22) (2020)
Tsvetelina H Baryakova, Seth C Ritter, Daniel T Tresnak, Benjamin J Hackel
Computationally Aided Discovery of LysEFm5 Variants with Improved Catalytic Activity and Stability. Applied and environmental microbiology 86 (4) (2020)
Nagamani Vunnam, Sophia Szymonski, Petra Hirsova, Gregory J Gores, Jonathan N Sachs, Benjamin J Hackel
Noncompetitive Allosteric Antagonism of Death Receptor 5 by a Synthetic Affibody Ligand. Biochemistry 59 (40) (2020)
Patrick S Lown, Benjamin J Hackel
Magnetic Bead-Immobilized Mammalian Cells Are Effective Targets to Enrich Ligand-Displaying Yeast. ACS combinatorial science 22 (5) (2020)
Alexander W Golinski, Patrick V Holec, Katelynn M Mischler, Benjamin J Hackel
Biophysical Characterization Platform Informs Protein Scaffold Evolvability. ACS combinatorial science 21 (4) (2019)
Lawrence A Stern, Patrick S Lown, Alexandra C Kobe, Lotfi Abou-Elkacem, Juergen K Willmann, Benjamin J Hackel
Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276. ACS combinatorial science 21 (3) (2019)
Pin-Kuang Lai, Daniel T Tresnak, Benjamin J Hackel
Identification and elucidation of proline-rich antimicrobial peptides with enhanced potency and delivery. Biotechnology and bioengineering 116 (10) (2019)
Wenjia Zhang, McKenzie L Coughlin, Joseph M Metzger, Benjamin J Hackel, Frank S Bates, Timothy P Lodge
Influence of Cholesterol and Bilayer Curvature on the Interaction of PPO-PEO Block Copolymers with Liposomes. Langmuir : the ACS journal of surfaces and colloids 35 (22) (2019)
Rakesh Bam, Makenna Laffey, Katharine Nottberg, Patrick S Lown, Benjamin J Hackel, Katheryne E Wilson
Affibody-Indocyanine Green Based Contrast Agent for Photoacoustic and Fluorescence Molecular Imaging of B7-H3 Expression in Breast Cancer. Bioconjugate chemistry 30 (6) (2019)
Justin R Klesmith, Lihe Su, Lan Wu, Ian A Schrack, Fay J Dufort, Alyssa Birt, Christine Ambrose, Benjamin J Hackel, Roy R Lobb, Paul D Rennert
Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins. Molecular pharmaceutics 16 (8) (2019)
Justin R Klesmith, Lan Wu, Roy R Lobb, Paul D Rennert, Benjamin J Hackel
Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design. Biochemistry 58 (48) (2019)
Seth C Ritter, Benjamin J Hackel
Validation and Stabilization of a Prophage Lysin of Clostridium perfringens by Using Yeast Surface Display and Coevolutionary Models. Applied and environmental microbiology 85 (10) (2019)
Feifan Du, Max A Kruziki, Elizabeth J Zudock, Yi Zhang, Patrick S Lown, Benjamin J Hackel
Engineering an EGFR-binding Gp2 domain for increased hydrophilicity. Biotechnology and bioengineering 116 (3) (2018)
Mihee Kim, Milan Vala, Christopher T Ertsgaard, Sang-Hyun Oh, Timothy P Lodge, Frank S Bates, Benjamin J Hackel
Surface Plasmon Resonance Study of the Binding of PEO-PPO-PEO Triblock Copolymer and PEO Homopolymer to Supported Lipid Bilayers. Langmuir : the ACS journal of surfaces and colloids 34 (23) (2018)
Brett A Case, Max A Kruziki, Sadie M Johnson, Benjamin J Hackel
Engineered Charge Redistribution of Gp2 Proteins through Guided Diversity for Improved PET Imaging of Epidermal Growth Factor Receptor. Bioconjugate chemistry 29 (5) (2018)
Clifford M Csizmar, Jacob R Petersburg, Thomas J Perry, Lakmal Rozumalski, Benjamin J Hackel, Carston R Wagner
Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density. Journal of the American Chemical Society 141 (1) (2018)
Max A Kruziki, Vidur Sarma, Benjamin J Hackel
Constrained Combinatorial Libraries of Gp2 Proteins Enhance Discovery of PD-L1 Binders. ACS combinatorial science 20 (7) (2018)
Clifford M Csizmar, Jacob R Petersburg, Alex Hendricks, Lawrence A Stern, Benjamin J Hackel, Carston R Wagner
Engineering Reversible Cell-Cell Interactions with Lipid Anchored Prosthetic Receptors. Bioconjugate chemistry 29 (4) (2018)
Seth C Ritter, Mike L Yang, Yiannis N Kaznessis, Benjamin J Hackel
Multispecies activity screening of microcin J25 mutants yields antimicrobials with increased specificity toward pathogenic Salmonella species relative to human commensal Escherichia coli. Biotechnology and bioengineering 115 (10) (2018)
Daniel R Woldring, Patrick V Holec, Lawrence A Stern, Yang Du, Benjamin J Hackel
A Gradient of Sitewise Diversity Promotes Evolutionary Fitness for Binder Discovery in a Three-Helix Bundle Protein Scaffold. Biochemistry 56 (11) (2017)
Wenjia Zhang, Karen J Haman, Joseph M Metzger, Benjamin J Hackel, Frank S Bates, Timothy P Lodge
Quantifying Binding of Ethylene Oxide-Propylene Oxide Block Copolymers with Lipid Bilayers. Langmuir : the ACS journal of surfaces and colloids 33 (44) (2017)
Evelyne M Houang, Karen J Haman, Mihee Kim, Wenjia Zhang, Dawn A Lowe, Yuk Y Sham, Timothy P Lodge, Benjamin J Hackel, Frank S Bates, Joseph M Metzger
Chemical End Group Modified Diblock Copolymers Elucidate Anchor and Chain Mechanism of Membrane Stabilization. Molecular pharmaceutics 14 (7) (2017)
Lawrence A Stern, Clifford M Csizmar, Daniel R Woldring, Carston R Wagner, Benjamin J Hackel
Titratable Avidity Reduction Enhances Affinity Discrimination in Mammalian Cellular Selections of Yeast-Displayed Ligands. ACS combinatorial science 19 (5) (2017)
Mihee Kim, Karen J Haman, Evelyne M Houang, Wenjia Zhang, Demetris Yannopoulos, Joseph M Metzger, Frank S Bates, Benjamin J Hackel
PEO-PPO Diblock Copolymers Protect Myoblasts from Hypo-Osmotic Stress In Vitro Dependent on Copolymer Size, Composition, and Architecture. Biomacromolecules 18 (7) (2017)
Patrick V Holec, Benjamin J Hackel
PyMOL360: Multi-user gamepad control of molecular visualization software. Journal of computational chemistry 37 (30) (2016)