Jonathan N Sachs

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 22

Top Topics

Molecular Dynamics

Energy Transfer

Sickle Cell Disease

Top Venues

ACS chemical neuroscience

Cancer biology & therapy

ACS bio & med chem Au

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Elly E Liao, Mu Yang, Noah Nathan Kochen, Nagamani Vunnam, Anthony R Braun, David M Ferguson, Jonathan N Sachs
Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology. Molecular neurobiology (2023)
Nagamani Vunnam, Mu Yang, Chih Hung Lo, Carolyn N Paulson, William D Fiers, Evan Huber, MaryJane Been, David M Ferguson, Jonathan N Sachs
Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling. ACS bio & med chem Au 3 (3) (2023)
Nagamani Vunnam, Malaney C Young, Elly E Liao, Chih Hung Lo, Evan Huber, MaryJane Been, David D Thomas, Jonathan N Sachs
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †. Cancer biology & therapy 24 (1) (2023)
Anil K Pandey, Caroline R Buchholz, Noah Nathan Kochen, William C K Pomerantz, Anthony R Braun, Jonathan N Sachs
pH Effects Can Dominate Chemical Shift Perturbations in 1 H, 15 N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. ACS chemical neuroscience 14 (4) (2023)
Nagamani Vunnam, Mu Yang, Chih Hung Lo, Carolyn N Paulson, William D Fiers, Evan Huber, MaryJane Been, David M Ferguson, Jonathan N Sachs
Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling. ACS bio & med chem Au 3 (3) (2023)
Nagamani Vunnam, Malaney C Young, Elly E Liao, Chih Hung Lo, Evan Huber, MaryJane Been, David D Thomas, Jonathan N Sachs
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †. Cancer biology & therapy 24 (1) (2023)
Nagamani Vunnam, Malaney C Young, Elly E Liao, Chih Hung Lo, Evan Huber, MaryJane Been, David D Thomas, Jonathan N Sachs
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †. Cancer biology & therapy 24 (1) (2023)
Anil K Pandey, Caroline R Buchholz, Noah Nathan Kochen, William C K Pomerantz, Anthony R Braun, Jonathan N Sachs
pH Effects Can Dominate Chemical Shift Perturbations in 1 H, 15 N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. ACS chemical neuroscience (2023)
Nagamani Vunnam, Malaney C Young, Elly E Liao, Chih Hung Lo, Evan Huber, MaryJane Been, David D Thomas, Jonathan N Sachs
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †. Cancer biology & therapy 24 (1) (2023)
Nagamani Vunnam, MaryJane Been, Evan Huber, Carolyn N Paulson, Sophia Szymonski, Benjamin J Hackel, Jonathan N Sachs
Discovery of a Non-competitive TNFR1 Antagonist Affibody with Picomolar Monovalent Potency That Does Not Affect TNFR2 Function. Molecular pharmaceutics (2023)
Anil K Pandey, Caroline R Buchholz, Noah Nathan Kochen, William C K Pomerantz, Anthony R Braun, Jonathan N Sachs
pH Effects Can Dominate Chemical Shift Perturbations in 1 H, 15 N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. ACS chemical neuroscience 14 (4) (2023)
Anil K Pandey, Caroline R Buchholz, Noah Nathan Kochen, William C K Pomerantz, Anthony R Braun, Jonathan N Sachs
pH Effects Can Dominate Chemical Shift Perturbations in 1 H, 15 N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. ACS chemical neuroscience 14 (4) (2023)
Anil K Pandey, Caroline R Buchholz, Noah Nathan Kochen, William C K Pomerantz, Anthony R Braun, Jonathan N Sachs
pH Effects Can Dominate Chemical Shift Perturbations in 1 H, 15 N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. ACS chemical neuroscience 14 (4) (2023)
Nagamani Vunnam, Malaney C Young, Elly E Liao, Chih Hung Lo, Evan Huber, MaryJane Been, David D Thomas, Jonathan N Sachs
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †. Cancer biology & therapy 24 (1) (2023)
Sneha Ratnapriya, Anthony R Braun, Héctor Cervera Benet, Danielle Carlson, Shilei Ding, Carolyn N Paulson, Neeraj Mishra, Jonathan N Sachs, Courtney C Aldrich, Andrés Finzi, Alon Herschhorn
Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry. ACS infectious diseases 8 (10) (2022)
Nagamani Vunnam, Scott Hansen, Dillon C Williams, MaryJane Olivia Been, Chih Hung Lo, Anil K Pandey, Carolyn N Paulson, John A Rohde, David D Thomas, Jonathan N Sachs, David K Wood
Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease. Biomacromolecules 23 (9) (2022)
Noah Nathan Kochen, Vivek Vasandani, Darren Seaney, Anil K Pandey, Michael A Walters, Anthony R Braun, Jonathan N Sachs
Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth. ACS chemical neuroscience 13 (17) (2022)
Anthony R Braun, Elly E Liao, Mian Horvath, Prakriti Kalra, Karen Acosta, Malaney C Young, Noah Nathan Kochen, Chih Hung Lo, Roland Brown, Michael D Evans, William C K Pomerantz, Elizabeth Rhoades, Kelvin C Luk, Razvan L Cornea, David D Thomas, Jonathan N Sachs
Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors. NPJ Parkinson's disease 7 (1) (2021)
Chih Hung Lo, Evan C Huber, Jonathan N Sachs
Conformational states of TNFR1 as a molecular switch for receptor function. Protein science : a publication of the Protein Society 29 (6) (2020)
Chih Hung Lo, Nitin K Pandey, Colin Kin-Wye Lim, Zhipeng Ding, Meixin Tao, David D Thomas, Ralf Langen, Jonathan N Sachs
Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells. ACS chemical neuroscience 11 (15) (2020)
Nagamani Vunnam, Sophia Szymonski, Petra Hirsova, Gregory J Gores, Jonathan N Sachs, Benjamin J Hackel
Noncompetitive Allosteric Antagonism of Death Receptor 5 by a Synthetic Affibody Ligand. Biochemistry 59 (40) (2020)
Chih Hung Lo, Tory M Schaaf, Benjamin D Grant, Colin Kin-Wye Lim, Prachi Bawaskar, Courtney C Aldrich, David D Thomas, Jonathan N Sachs
Noncompetitive inhibitors of TNFR1 probe conformational activation states. Science signaling 12 (592) (2019)