Ute A Hellmich

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 26

Top Topics

Bacillus Subtilis

Electron Microscopy

Protein Protein

Top Venues

Angewandte Chemie (International ed. in English)

Biomolecular NMR assignments

Nature communications

Communications chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Maria Dell, Mai Anh Tran, Michael J Capper, Srividhya Sundaram, Jonas Fiedler, Jesko Koehnke, Ute A Hellmich, Christian Hertweck
Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Maria Dell, Mai Anh Tran, Michael J Capper, Srividhya Sundaram, Jonas Fiedler, Jesko Koehnke, Ute A Hellmich, Christian Hertweck
Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Maria Dell, Mai Anh Tran, Michael J Capper, Srividhya Sundaram, Jonas Fiedler, Jesko Koehnke, Ute A Hellmich, Christian Hertweck
Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions. Angewandte Chemie (International ed. in English) 63 (9) (2024)
Benedikt Goretzki, Christoph Wiedemann, Brett A McCray, Stefan L Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K Donohue, Cy Michael Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J Sumner, Gerhard Hummer, Ute A Hellmich
Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity. Nature communications 14 (1) (2023)
Maria Dell, Mai Anh Tran, Michael J Capper, Srividhya Sundaram, Jonas Fiedler, Jesko Koehnke, Ute A Hellmich, Christian Hertweck
Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions. Angewandte Chemie (International ed. in English) (2023)
Maria Dell, Mai Anh Tran, Michael J Capper, Srividhya Sundaram, Jonas Fiedler, Jesko Koehnke, Ute A Hellmich, Christian Hertweck
Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions. Angewandte Chemie (International ed. in English) (2023)
Maria Dell, Mai Anh Tran, Michael J Capper, Srividhya Sundaram, Jonas Fiedler, Jesko Koehnke, Ute A Hellmich, Christian Hertweck
Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions. Angewandte Chemie (International ed. in English) (2023)
Yuko Bando, Yu Hou, Lydia Seyfarth, Jannik Probst, Sebastian Götze, Marta Bogacz, Ute A Hellmich, Pierre Stallforth, Maria Mittag, Hans-Dieter Arndt
Total Synthesis and Structure Correction of the Cyclic Lipodepsipeptide Orfamide A. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (20) (2022)
Victor Hugo Pérez Carrillo, Dania Rose-Sperling, Mai Anh Tran, Christoph Wiedemann, Ute A Hellmich
Backbone NMR assignment of the nucleotide binding domain of the Bacillus subtilis ABC multidrug transporter BmrA in the post-hydrolysis state. Biomolecular NMR assignments 16 (1) (2022)
Liying Zhang, Charlotte Simonsen, Lucie Zimova, Kaituo Wang, Lavanya Moparthi, Rachelle Gaudet, Maria Ekoff, Gunnar P Nilsson, Ute A Hellmich, Viktorie Vlachova, Pontus Emanuel Gourdon, Peter M Zygmunt
Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function. Nature communications 13 (1) (2022)
Yamina El Hamdaoui, Fang Zheng, Nikolas Fritz, Lian Ye, Mai Anh Tran, Kevin Schwickert, Tanja Schirmeister, Albert Braeuning, Dajana Lichtenstein, Ute A Hellmich, Dorothee Weikert, Markus Heinrich, Giulia Treccani, Michael K E Schäfer, Gabriel Nowak, Bernd Nürnberg, Christian Alzheimer, Christian P Müller, Friedland Kristina
Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs. Molecular psychiatry (2022)
Benedikt Goretzki, Frederike Tebbe, Sarah-Ana Mitrovic, Ute A Hellmich
Backbone NMR assignments of the extensive human and chicken TRPV4 N-terminal intrinsically disordered regions as important players in ion channel regulation. Biomolecular NMR assignments 16 (2) (2022)
Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, Josef Kehrein, Markus Zehe, Christoph Wiedemann, Ute A Hellmich, Ruth Brenk, Hermann Schindelin, Christoph A Sotriffer
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97. Communications chemistry 5 (1) (2022)
Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, Josef Kehrein, Markus Zehe, Christoph Wiedemann, Ute A Hellmich, Ruth Brenk, Hermann Schindelin, Christoph A Sotriffer
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97. Communications chemistry 5 (1) (2022)
Christoph Wiedemann, Benedikt Goretzki, Zoe N Merz, Frederike Tebbe, Pauline Schmitt, Ute A Hellmich
Extent of intrinsic disorder and NMR chemical shift assignments of the distal N-termini from human TRPV1, TRPV2 and TRPV3 ion channels. Biomolecular NMR assignments 16 (2) (2022)
Patrick Johe, Sascha Jung, Erik Endres, Christian Kersten, Collin Zimmer, Weixiang Ye, Carsten Sönnichsen, Ute A Hellmich, Christoph Sotriffer, Tanja Schirmeister, Hannes Neuweiler
Warhead Reactivity Limits the Speed of Inhibition of the Cysteine Protease Rhodesain. ACS chemical biology 16 (4) (2021)
Lars J Wesenberg, Erika Diehl, Till J B Zähringer, Carolin Dörr, Dieter Schollmeyer, Akihiro Shimizu, Jun-Ichi Yoshida, Ute A Hellmich, Siegfried R Waldvogel
Metal-Free Twofold Electrochemical C-H Amination of Activated Arenes: Application to Medicinally Relevant Precursor Synthesis. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (72) (2020)
Benedikt Junglas, Roberto Orru, Amelie Axt, Carmen Siebenaller, Wieland Steinchen, Jennifer Heidrich, Ute A Hellmich, Nadja Hellmann, Eva Wolf, Stefan A L Weber, Dirk Schneider
IM30 IDPs form a membrane-protective carpet upon super-complex disassembly. Communications biology 3 (1) (2020)
Johannes C B Dietschreit, Annika Wagner, T Anh Le, Philipp Klein, Hermann Schindelin, Jason Sirleaf, Bernd Engels, Ute A Hellmich, Christian Ochsenfeld
Predicting 19 F NMR Chemical Shifts: A Combined Computational and Experimental Study of a Trypanosomal Oxidoreductase-Inhibitor Complex. Angewandte Chemie (International ed. in English) 59 (31) (2020)
Dania Rose-Sperling, Mai Anh Tran, Luca M Lauth, Benedikt Goretzki, Ute A Hellmich
19F NMR as a versatile tool to study membrane protein structure and dynamics. Biological chemistry 400 (10) (2020)
Robert C Ford, Ute A Hellmich
What monomeric nucleotide binding domains can teach us about dimeric ABC proteins. FEBS letters 594 (23) (2020)
Julia C Heiby, Benedikt Goretzki, Christopher M Johnson, Ute A Hellmich, Hannes Neuweiler
Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk. Nature communications 10 (1) (2019)
Benedikt Millies, Franziska von Hammerstein, Andrea Gellert, Stefan Hammerschmidt, Fabian Barthels, Ulrike Göppel, Melissa Immerheiser, Fabian Elgner, Nathalie Jung, Michael Basic, Christian Kersten, Werner Kiefer, Jochen Bodem, Eberhard Hildt, Maike Windbergs, Ute A Hellmich, Tanja Schirmeister
Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases. Journal of medicinal chemistry 62 (24) (2019)
Benedikt Goretzki, Julia C Heiby, Carolin Hacker, Hannes Neuweiler, Ute A Hellmich
NMR assignments of a dynamically perturbed and dimerization inhibited N-terminal domain variant of a spider silk protein from E. australis. Biomolecular NMR assignments 14 (1) (2019)
Annika Wagner, Thien Anh Le, Martha Brennich, Philipp Klein, Nicole Bader, Erika Diehl, Daniel Paszek, A Katharina Weickhmann, Natalie Dirdjaja, R Luise Krauth-Siegel, Bernd Engels, Till Opatz, Hermann Schindelin, Ute A Hellmich
Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes. Angewandte Chemie (International ed. in English) 58 (11) (2019)
Roberta Ettari, Santo Previti, Santina Maiorana, Giorgio Amendola, Annika Wagner, Sandro Cosconati, Tanja Schirmeister, Ute A Hellmich, Maria Zappalà
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis. Journal of medicinal chemistry 62 (23) (2019)