Brian S J Blagg

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Topics

Top Venues

ACS medicinal chemistry letters

ACS chemical biology

Medicinal research reviews

This page only lists publications with an associated author ORCID identifier.

Publications

Verodia Charlestin, Elijah Tan, Carlos Eduardo Arias-Matus, Junmin Wu, Maria Cristina Miranda-Vergara, Mijoon Lee, Man Wang, Dharma T Nannapaneni, Parinda Tennakoon, Brian S J Blagg, Brandon L Ashfeld, William Kaliney, Jun Li, Laurie E Littlepage
Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer. Cancers 16 (15) (2024)
Verodia Charlestin, Elijah Tan, Carlos Eduardo Arias-Matus, Junmin Wu, Maria Cristina Miranda-Vergara, Mijoon Lee, Man Wang, Dharma T Nannapaneni, Parinda Tennakoon, Brian S J Blagg, Brandon L Ashfeld, William Kaliney, Jun Li, Laurie E Littlepage
Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer. Cancers 16 (15) (2024)
Verodia Charlestin, Elijah Tan, Carlos Eduardo Arias-Matus, Junmin Wu, Maria Cristina Miranda-Vergara, Mijoon Lee, Man Wang, Dharma T Nannapaneni, Parinda Tennakoon, Brian S J Blagg, Brandon L Ashfeld, William Kaliney, Jun Li, Laurie E Littlepage
Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer. Cancers 16 (15) (2024)
Eva Amatya, Chitra Subramanian, Mark S Cohen, Brian S J Blagg
Development of Hsp90 C-terminal inhibitors with noviomimetics that manifest anti-proliferative activities. RSC medicinal chemistry 15 (3) (2024)
Eva Amatya, Chitra Subramanian, Mark S Cohen, Brian S J Blagg
Development of Hsp90 C-terminal inhibitors with noviomimetics that manifest anti-proliferative activities. RSC medicinal chemistry 15 (3) (2024)
Michael A Serwetnyk, Vincent M Crowley, Christopher M Brackett, Trever R Carter, Asif Elahi, Vamsi Krishna Kommalapati, Ahmed Chadli, Brian S J Blagg
Enniatin A Analogues as Novel Hsp90 Inhibitors that Modulate Triple-Negative Breast Cancer. ACS medicinal chemistry letters 14 (12) (2023)
Tyelor S Reynolds, Brian S J Blagg
Synthesis and Validation of the First Cell-Impermeable Hsp90α-Selective Inhibitors. ACS medicinal chemistry letters 14 (9) (2023)
Michael A Serwetnyk, Vincent M Crowley, Christopher M Brackett, Trever R Carter, Asif Elahi, Vamsi Krishna Kommalapati, Ahmed Chadli, Brian S J Blagg
Enniatin A Analogues as Novel Hsp90 Inhibitors that Modulate Triple-Negative Breast Cancer. ACS medicinal chemistry letters 14 (12) (2023)
Michael A Serwetnyk, Vincent M Crowley, Christopher M Brackett, Trever R Carter, Asif Elahi, Vamsi Krishna Kommalapati, Ahmed Chadli, Brian S J Blagg
Enniatin A Analogues as Novel Hsp90 Inhibitors that Modulate Triple-Negative Breast Cancer. ACS medicinal chemistry letters 14 (12) (2023)
Michael A Serwetnyk, Vincent M Crowley, Christopher M Brackett, Trever R Carter, Asif Elahi, Vamsi Krishna Kommalapati, Ahmed Chadli, Brian S J Blagg
Enniatin A Analogues as Novel Hsp90 Inhibitors that Modulate Triple-Negative Breast Cancer. ACS medicinal chemistry letters 14 (12) (2023)
Bradley M Keegan, Brian S J Blagg
A Split Renilla Luciferase Complementation Assay for the Evaluation of Hsp90/Aha1 Complex Disruptors and Their Activity at the Aha1 C-Terminal Domain. ACS chemical biology 18 (1) (2022)
Sanket J Mishra, Tyelor S Reynolds, Taylor Merfeld, Maurie Balch, Shuxia Peng, Junpeng Deng, Robert Matts, Brian S J Blagg
Structure-Activity Relationship Study of Tertiary Alcohol Hsp90α-Selective Inhibitors with Novel Binding Mode. ACS medicinal chemistry letters 13 (12) (2022)
Bradley M Keegan, Brian S J Blagg
A Split Renilla Luciferase Complementation Assay for the Evaluation of Hsp90/Aha1 Complex Disruptors and Their Activity at the Aha1 C-Terminal Domain. ACS chemical biology 18 (1) (2022)
Bradley M Keegan, Brian S J Blagg
A Split Renilla Luciferase Complementation Assay for the Evaluation of Hsp90/Aha1 Complex Disruptors and Their Activity at the Aha1 C-Terminal Domain. ACS chemical biology 18 (1) (2022)
Kyler W Pugh, Marim Alnaed, Christopher M Brackett, Brian S J Blagg
The biology and inhibition of glucose-regulated protein 94/gp96. Medicinal research reviews 42 (6) (2022)
Xiaozheng Dou, Bhargav A Patel, Terin D'Amico, Chitra Subramanian, Eric Cousineau, Yi Yi, Mark Cohen, Brian S J Blagg
Synthesis and Evaluation of Simplified Cruentaren A Analogues. The Journal of organic chemistry 87 (15) (2022)
Sanket J Mishra, Tyelor S Reynolds, Taylor Merfeld, Maurie Balch, Shuxia Peng, Junpeng Deng, Robert Matts, Brian S J Blagg
Structure-Activity Relationship Study of Tertiary Alcohol Hsp90α-Selective Inhibitors with Novel Binding Mode. ACS medicinal chemistry letters 13 (12) (2022)
Kiran Chinthapally, Brian S J Blagg, Brandon L Ashfeld
Syntheses of Symmetrical and Unsymmetrical Lysobisphosphatidic Acid Derivatives. The Journal of organic chemistry 87 (15) (2022)
Bradley M Keegan, Brian S J Blagg
A Split Renilla Luciferase Complementation Assay for the Evaluation of Hsp90/Aha1 Complex Disruptors and Their Activity at the Aha1 C-Terminal Domain. ACS chemical biology (2022)
Bradley M Keegan, Kevin C Catalfano, Monimoy Banerjee, Brian S J Blagg
Synthesis and Evaluation of Small Molecule Disruptors of the Aha1/Hsp90 Complex for the Reduction of Tau Aggregation. ACS medicinal chemistry letters 13 (5) (2022)
Sanket J Mishra, Anuj Khandelwal, Monimoy Banerjee, Maurie Balch, Shuxia Peng, Rachel E Davis, Taylor Merfeld, Vitumbiko Munthali, Junpeng Deng, Robert L Matts, Brian S J Blagg
Selective Inhibition of the Hsp90α Isoform. Angewandte Chemie (International ed. in English) 60 (19) (2021)
Sanket J Mishra, Weiya Liu, Kristin Beebe, Monimoy Banerjee, Caitlin N Kent, Vitumbiko Munthali, John Koren, John A Taylor, Leonard M Neckers, Jeffrey Holzbeierlein, Brian S J Blagg
The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition. Journal of medicinal chemistry 64 (3) (2021)
Yssa A Rodriguez, Sukmanjit Kaur, Erika Nolte, Zhang Zheng, Brian S J Blagg, Rick T Dobrowsky
Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons. ACS chemical neuroscience 12 (16) (2021)
Subhabrata Chaudhury, Bradley M Keegan, Brian S J Blagg
The role and therapeutic potential of Hsp90, Hsp70, and smaller heat shock proteins in peripheral and central neuropathies. Medicinal research reviews 41 (1) (2020)
Taoda Shi, E M Kithsiri Wijeratne, Cristian Solano, Andrew J Ambrose, Alison B Ross, Charles Norwood, Charles K Orido, Tigran Grigoryan, Joseph Tillotson, Minjin Kang, Gang Luo, Bradley M Keegan, Wenhao Hu, Brian S J Blagg, Donna D Zhang, A A Leslie Gunatilaka, Eli Chapman
An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol. Biochemistry 58 (30) (2019)
Nanette L S Que, Vincent M Crowley, Adam S Duerfeldt, Jinbo Zhao, Caitlin N Kent, Brian S J Blagg, Daniel T Gewirth
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. Journal of medicinal chemistry 61 (7) (2018)
Dustin J E Huard, Vincent M Crowley, Yuhong Du, Ricardo A Cordova, Zheying Sun, Moya O Tomlin, Chad A Dickey, John Koren, Laura J Blair, Haian Fu, Brian S J Blagg, Raquel L Lieberman
Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma. ACS chemical biology 13 (4) (2018)
Xinyue Zhang, Chengyuan Li, Stephen C Fowler, Zheng Zhang, Brian S J Blagg, Rick T Dobrowsky
Targeting Heat Shock Protein 70 to Ameliorate c-Jun Expression and Improve Demyelinating Neuropathy. ACS chemical neuroscience 9 (2) (2017)
Gaurav Garg, Leah K Forsberg, Huiping Zhao, Brian S J Blagg
Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C-terminal Inhibitors. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (65) (2017)
Katherine M Byrd, Caitlin N Kent, Brian S J Blagg
Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C-Terminal Inhibitors. ChemMedChem 12 (24) (2017)
Vincent M Crowley, Dustin J E Huard, Raquel L Lieberman, Brian S J Blagg
Second Generation Grp94-Selective Inhibitors Provide Opportunities for the Inhibition of Metastatic Cancer. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (62) (2017)
Sanket J Mishra, Suman Ghosh, Andrew R Stothert, Chad A Dickey, Brian S J Blagg
Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold. ACS chemical biology 12 (1) (2016)