Andrew J Ambrose

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 29

Top Venues

Journal of medicinal chemistry

Journal of the American Chemical Society

Biochemistry

Chemical research in toxicology

The University of Arizona (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

The University of Arizona

United States

PHD :: Pharmacology and Toxicology

Publications

Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry (2024)
Jack Godek, Jared Sivinski, Edmond R Watson, Felicidad Lebario, Wenli Xu, Mckayla Stevens, Christopher J Zerio, Andrew J Ambrose, Xiaoyi Zhu, Carlee A Trindl, Donna D Zhang, Steven M Johnson, Gabriel C Lander, Eli Chapman
Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. Journal of the American Chemical Society 146 (30) (2024)
Jack Godek, Jared Sivinski, Edmond R Watson, Felicidad Lebario, Wenli Xu, Mckayla Stevens, Christopher J Zerio, Andrew J Ambrose, Xiaoyi Zhu, Carlee A Trindl, Donna D Zhang, Steven M Johnson, Gabriel C Lander, Eli Chapman
Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. Journal of the American Chemical Society 146 (30) (2024)
Jack Godek, Jared Sivinski, Edmond R Watson, Felicidad Lebario, Wenli Xu, Mckayla Stevens, Christopher J Zerio, Andrew J Ambrose, Xiaoyi Zhu, Carlee A Trindl, Donna D Zhang, Steven M Johnson, Gabriel C Lander, Eli Chapman
Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. Journal of the American Chemical Society (2024)
Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry 63 (3) (2024)
Andrew J Ambrose, Christopher J Zerio, Jared Sivinski, Xiaoyi Zhu, Jack Godek, Jonathan L Sanchez, May Khanna, Rajesh Khanna, Luke L Lairson, Donna D Zhang, Eli Chapman
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins. Biochemistry 63 (3) (2024)
Kurt S Van Horn, Dongju Wang, Daniel Medina-Cleghorn, Peter S Lee, Clifford Bryant, Chad Altobelli, Priyadarshini Jaishankar, Kevin K Leung, Raymond A Ng, Andrew J Ambrose, Yinyan Tang, Michelle R Arkin, Adam R Renslo
Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. Journal of the American Chemical Society 145 (18) (2023)
Kurt S Van Horn, Dongju Wang, Daniel Medina-Cleghorn, Peter S Lee, Clifford Bryant, Chad Altobelli, Priyadarshini Jaishankar, Kevin K Leung, Raymond A Ng, Andrew J Ambrose, Yinyan Tang, Michelle R Arkin, Adam R Renslo
Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. Journal of the American Chemical Society 145 (18) (2023)
Kurt S Van Horn, Dongju Wang, Daniel Medina-Cleghorn, Peter S Lee, Clifford Bryant, Chad Altobelli, Priyadarshini Jaishankar, Kevin K Leung, Raymond A Ng, Andrew J Ambrose, Yinyan Tang, Michelle R Arkin, Adam R Renslo
Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. Journal of the American Chemical Society 145 (18) (2023)
Kurt S Van Horn, Dongju Wang, Daniel Medina-Cleghorn, Peter S Lee, Clifford Bryant, Chad Altobelli, Priyadarshini Jaishankar, Kevin K Leung, Raymond A Ng, Andrew J Ambrose, Yinyan Tang, Michelle R Arkin, Adam R Renslo
Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. Journal of the American Chemical Society (2023)
Kurt S Van Horn, Dongju Wang, Daniel Medina-Cleghorn, Peter S Lee, Clifford Bryant, Chad Altobelli, Priyadarshini Jaishankar, Kevin K Leung, Raymond A Ng, Andrew J Ambrose, Yinyan Tang, Michelle R Arkin, Adam R Renslo
Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. Journal of the American Chemical Society 145 (18) (2023)
Kurt S Van Horn, Dongju Wang, Daniel Medina-Cleghorn, Peter S Lee, Clifford Bryant, Chad Altobelli, Priyadarshini Jaishankar, Kevin K Leung, Raymond A Ng, Andrew J Ambrose, Yinyan Tang, Michelle R Arkin, Adam R Renslo
Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6. Journal of the American Chemical Society 145 (18) (2023)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry 66 (1) (2022)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry 66 (1) (2022)
Christopher J Zerio, Jared Sivinski, E M Kithsiri Wijeratne, Ya-Ming Xu, Duc T Ngo, Andrew J Ambrose, Luis Villa-Celis, Niloofar Ghadirian, Michael W Clarkson, Donna D Zhang, Nancy C Horton, A A Leslie Gunatilaka, Raimund Fromme, Eli Chapman
Physachenolide C is a Potent, Selective BET Inhibitor. Journal of medicinal chemistry (2022)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry (2022)
Christopher J Zerio, Jared Sivinski, E M Kithsiri Wijeratne, Ya-Ming Xu, Duc T Ngo, Andrew J Ambrose, Luis Villa-Celis, Niloofar Ghadirian, Michael W Clarkson, Donna D Zhang, Nancy C Horton, A A Leslie Gunatilaka, Raimund Fromme, Eli Chapman
Physachenolide C is a Potent, Selective BET Inhibitor. Journal of medicinal chemistry 66 (1) (2022)
Christopher J Zerio, Jared Sivinski, E M Kithsiri Wijeratne, Ya-Ming Xu, Duc T Ngo, Andrew J Ambrose, Luis Villa-Celis, Niloofar Ghadirian, Michael W Clarkson, Donna D Zhang, Nancy C Horton, A A Leslie Gunatilaka, Raimund Fromme, Eli Chapman
Physachenolide C is a Potent, Selective BET Inhibitor. Journal of medicinal chemistry 66 (1) (2022)
Christopher J Zerio, Jared Sivinski, E M Kithsiri Wijeratne, Ya-Ming Xu, Duc T Ngo, Andrew J Ambrose, Luis Villa-Celis, Niloofar Ghadirian, Michael W Clarkson, Donna D Zhang, Nancy C Horton, A A Leslie Gunatilaka, Raimund Fromme, Eli Chapman
Physachenolide C is a Potent, Selective BET Inhibitor. Journal of medicinal chemistry 66 (1) (2022)
Andrew J Ambrose, Jared Sivinski, Christopher J Zerio, Xiaoyi Zhu, Jack Godek, Vlad K Kumirov, Teresa Coma Brujas, Joan Torra Garcia, Anandhan Annadurai, Cody J Schmidlin, Alyssa Werner, Taoda Shi, Reza Beheshti Zavareh, Luke L Lairson, Donna D Zhang, Eli Chapman
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. Journal of medicinal chemistry 66 (1) (2022)
Christopher J Zerio, Tyler A Cunningham, Allison S Tulino, Erin A Alimusa, Thomas M Buckley, Kohlson T Moore, Matthew Dodson, Nathan C Wilson, Andrew J Ambrose, Taoda Shi, Jared Sivinski, Derek J Essegian, Donna D Zhang, Stephan C Schürer, Jonathan H Schatz, Eli Chapman
Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. Journal of medicinal chemistry 64 (21) (2021)
Andrew J Ambrose, Eli Chapman
Function, Therapeutic Potential, and Inhibition of Hsp70 Chaperones. Journal of medicinal chemistry 64 (11) (2021)
Andrew J Ambrose, Nhan T Pham, Jared Sivinski, Larissa Guimarães, Niloufar Mollasalehi, Paula Christine Jimenez, Maria Alba Abad, Jeyaprakash Arulanandam, Steven Shave, Leticia Veras Costa-Lotufo, James J La Clair, Manfred Auer, Eli Chapman
A two-step resin based approach to reveal survivin-selective fluorescent probes. RSC chemical biology 2 (1) (2020)
Taoda Shi, E M Kithsiri Wijeratne, Cristian Solano, Andrew J Ambrose, Alison B Ross, Charles Norwood, Charles K Orido, Tigran Grigoryan, Joseph Tillotson, Minjin Kang, Gang Luo, Bradley M Keegan, Wenhao Hu, Brian S J Blagg, Donna D Zhang, A A Leslie Gunatilaka, Eli Chapman
An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol. Biochemistry 58 (30) (2019)
Sanofar Abdeen, Trent Kunkle, Nilshad Salim, Anne-Marie Ray, Najiba Mammadova, Corey Summers, Mckayla Stevens, Andrew J Ambrose, Yangshin Park, Peter G Schultz, Arthur L Horwich, Quyen Q Hoang, Eli Chapman, Steven M Johnson
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA). Journal of medicinal chemistry 61 (16) (2018)
Liberty François-Moutal, Shahriyar Jahanbakhsh, Andrew D L Nelson, Debashish Ray, David D Scott, Matthew R Hennefarth, Aubin Moutal, Samantha Perez-Miller, Andrew J Ambrose, Ahmed Al-Shamari, Philippe Coursodon, Bessie Meechoovet, Rebecca Reiman, Eric Lyons, Mark Beilstein, Eli Chapman, Quaid D Morris, Kendall Van Keuren-Jensen, Timothy R Hughes, Rajesh Khanna, Carla Koehler, Joanna Jen, Vijay Gokhale, May Khanna
A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). ACS chemical biology 13 (10) (2018)
Trent Kunkle, Sanofar Abdeen, Nilshad Salim, Anne-Marie Ray, Mckayla Stevens, Andrew J Ambrose, José Victorino, Yangshin Park, Quyen Q Hoang, Eli Chapman, Steven M Johnson
Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. Journal of medicinal chemistry 61 (23) (2018)
Joseph Tillotson, Christopher J Zerio, Bryan Harder, Andrew J Ambrose, Kevin S Jung, MinJin Kang, Donna D Zhang, Eli Chapman
Arsenic Compromises Both p97 and Proteasome Functions. Chemical research in toxicology 30 (7) (2017)
Andrew J Ambrose, Evelyne A Santos, Paula C Jimenez, Danilo D Rocha, Diego V Wilke, Paolo Beuzer, Josh Axelrod, Ananda Kumar Kanduluru, Philip L Fuchs, Hu Cang, Leticia Veras Costa-Lotufo, Eli Chapman, James J La Clair
Ritterostatin GN 1N , a Cephalostatin-Ritterazine Bis-steroidal Pyrazine Hybrid, Selectively Targets GRP78. Chembiochem : a European journal of chemical biology 18 (6) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Andrew J Ambrose