Cecilia Pozzi

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Venues

Journal of medicinal chemistry

ACS infectious diseases

International journal of molecular sciences

Chemistry (Weinheim an der Bergstrasse, Germany)

University of Siena

Universita degli Studi di Modena e Reggio Emilia (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Siena Nov 01 2019

Italy

Associate Professor :: Dept of Biotechnology, Chemistry and Pharmacy

University of Siena Nov 01 2016 - Oct 31 2019

Italy

Assistant professor (Senior Researcher) :: Dept of Biotechnology, Chemistry and Pharmacy

University of Siena Jul 15 2014 - Oct 31 2016

Italy

Postdoctoral fellow :: Dept of Biotechnology, Chemistry and Pharmacy

Interuniversity Consortium for Magnetic Resonance Mar 24 2014 - May 23 2014

Italy

Scholarship holder :: Dept of Biotechnology, Chemistry and Pharmacy (University of Siena)

University of Siena Feb 01 2012 - Feb 28 2014

Italy

PostDoc :: Dept of Chemistry/Biotechnology, Chemistry and Pharmacy

Interuniversity Consortium for Magnetic Resonance Nov 01 2010 - Jan 31 2012

Italy

Scholarship holder :: Dept of Chemistry (University of Siena)

University of Siena Oct 01 2007 - Sep 30 2010

Italy

PhD student :: Dept of Chemistry

Education History

Universita degli Studi di Modena e Reggio Emilia Oct 01 2002 - Jul 18 2007

Italy

MSC :: Dept of Pharmacy

Publications

Giusy Tassone, Cecilia Pozzi, Stefano Mangani
Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. International journal of molecular sciences 25 (15) (2024)
Giusy Tassone, Cecilia Pozzi, Stefano Mangani
Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. International journal of molecular sciences 25 (15) (2024)
Valeria Francesconi, Marco Rizzo, Cecilia Pozzi, Lorenzo Tagliazucchi, Claude U Konchie Simo, Giulia Saporito, Giacomo Landi, Stefano Mangani, Anna Carbone, Silvia Schenone, Nuno Santarém, Joana Tavares, Anabela-Cordeiro da Silva, Maria Paola Costi, Michele Tonelli
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti- Trypanosoma brucei Agents. ACS infectious diseases 10 (8) (2024)
Valeria Francesconi, Marco Rizzo, Cecilia Pozzi, Lorenzo Tagliazucchi, Claude U Konchie Simo, Giulia Saporito, Giacomo Landi, Stefano Mangani, Anna Carbone, Silvia Schenone, Nuno Santarém, Joana Tavares, Anabela-Cordeiro da Silva, Maria Paola Costi, Michele Tonelli
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti- Trypanosoma brucei Agents. ACS infectious diseases (2024)
Cecilia Pozzi, Anne Vanet, Valeria Francesconi, Lorenzo Tagliazucchi, Giusy Tassone, Alberto Venturelli, Francesca Spyrakis, Marco Mazzorana, Maria Paola Costi, Michele Tonelli
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective. Journal of medicinal chemistry 66 (6) (2023)
Cecilia Pozzi, Anne Vanet, Valeria Francesconi, Lorenzo Tagliazucchi, Giusy Tassone, Alberto Venturelli, Francesca Spyrakis, Marco Mazzorana, Maria Paola Costi, Michele Tonelli
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective. Journal of medicinal chemistry (2023)
Cecilia Pozzi, Anne Vanet, Valeria Francesconi, Lorenzo Tagliazucchi, Giusy Tassone, Alberto Venturelli, Francesca Spyrakis, Marco Mazzorana, Maria Paola Costi, Michele Tonelli
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective. Journal of medicinal chemistry 66 (6) (2023)
Cecilia Pozzi, Anne Vanet, Valeria Francesconi, Lorenzo Tagliazucchi, Giusy Tassone, Alberto Venturelli, Francesca Spyrakis, Marco Mazzorana, Maria Paola Costi, Michele Tonelli
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective. Journal of medicinal chemistry (2023)
Cecilia Pozzi, Anne Vanet, Valeria Francesconi, Lorenzo Tagliazucchi, Giusy Tassone, Alberto Venturelli, Francesca Spyrakis, Marco Mazzorana, Maria Paola Costi, Michele Tonelli
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective. Journal of medicinal chemistry (2023)
Giusy Tassone, Marco Mazzorana, Stefano Mangani, Elena Petricci, Elena Cini, Giuseppe Giannini, Cecilia Pozzi, Samuele Maramai
Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor. International journal of molecular sciences 23 (16) (2022)
Luca Costantino, Stefania Ferrari, Matteo Santucci, Outi M H Salo-Ahen, Emanuele Carosati, Silvia Franchini, Angela Lauriola, Cecilia Pozzi, Matteo Trande, Gaia Gozzi, Puneet Saxena, Giuseppe Cannazza, Lorena Losi, Daniela Cardinale, Alberto Venturelli, Antonio Quotadamo, Pasquale Linciano, Lorenzo Tagliazucchi, Maria Gaetana Moshella, Remo Guerrini, Salvatore Pacifico, Rosaria Luciani, Filippo Genovese, Stefan Henrich, Silvia Alboni, Nuno Santarem, Anabela da Silva Cordeiro, Elisa Giovannetti, Godefridus J Peters, Paolo Pinton, Alessandro Rimessi, Gabriele Cruciani, Robert M Stroud, Rebecca C Wade, Stefano Mangani, Gaetano Marverti, Domenico D'Arca, Glauco Ponterini, Maria Paola Costi
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth. eLife 11 (2022)
Ina Poehner, Antonio Quotadamo, Joanna Panecka-Hofman, Rosaria Luciani, Matteo Santucci, Pasquale Linciano, Giacomo Landi, Flavio Di Pisa, Lucia Dello Iacono, Cecilia Pozzi, Stefano Mangani, Sheraz Gul, Gesa Witt, Bernhard Ellinger, Maria Kuzikov, Nuno Santarem, Anabela Cordeiro-da-Silva, Maria Paola Costi, Alberto Venturelli, Rebecca C Wade
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. Journal of medicinal chemistry 65 (13) (2022)
Tommaso Palomba, Giusy Tassone, Carmine Vacca, Matteo Bartalucci, Aurora Valeri, Cecilia Pozzi, Simon Cross, Lydia Siragusa, Jenny Desantis
Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design. International journal of molecular sciences 23 (22) (2022)
Giusy Tassone, Marco Mazzorana, Cecilia Pozzi
Structural Basis of Parasitic HSP90 ATPase Inhibition by Small Molecules. Pharmaceuticals (Basel, Switzerland) 15 (11) (2022)
Alice Legru, Federica Verdirosa, Yen Vo-Hoang, Giusy Tassone, Filippo Vascon, Caitlyn A Thomas, Filomena Sannio, Giuseppina Corsica, Manuela Benvenuti, Georges Feller, Rémi Coulon, Francesca Marcoccia, Savannah Rowane Devente, Ezeddine Bouajila, Catherine Piveteau, Florence Leroux, Rebecca Deprez-Poulain, Benoît Deprez, Patricia Licznar-Fajardo, Michael W Crowder, Laura Cendron, Cecilia Pozzi, Stefano Mangani, Jean Denis Docquier, Jean-François Hernandez, Laurent Gavara
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates. Journal of medicinal chemistry (2022)
Giusy Tassone, Marco Paolino, Cecilia Pozzi, Annalisa Reale, Laura Salvini, Gianluca Giorgi, Maurizio Orlandini, Federico Galvagni, Stefano Mangani, Xuchun Yang, Benedetta Carlotti, Fausto Ortica, Loredana Latterini, Massimo Olivucci, Andrea Cappelli
Xanthopsin-Like Systems via Site-Specific Click-Functionalization of a Retinoic Acid Binding Protein. Chembiochem : a European journal of chemical biology (2021)
Silvia Ciambellotti, Alessandro Pratesi, Giusy Tassone, Paola Turano, Stefano Mangani, Cecilia Pozzi
Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (59) (2021)
Giusy Tassone, Giacomo Landi, Pasquale Linciano, Valeria Francesconi, Michele Tonelli, Lorenzo Tagliazucchi, Maria Paola Costi, Stefano Mangani, Cecilia Pozzi
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase. Pharmaceuticals (Basel, Switzerland) 14 (7) (2021)
Matteo Santucci, Rosaria Luciani, Eleonora Gianquinto, Cecilia Pozzi, Flavio di Pisa, Lucia Dello Iacono, Giacomo Landi, Lorenzo Tagliazucchi, Stefano Mangani, Francesca Spyrakis, Maria Paola Costi
Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases. Pharmaceuticals (Basel, Switzerland) 14 (12) (2021)
Giusy Tassone, Maurizio Orlandini, Massimo Olivucci, Cecilia Pozzi
Validation of Recombinant Chicken Liver Bile Acid Binding Protein as a Tool for Cholic Acid Hosting. Biomolecules 11 (5) (2021)
Cecilia Pozzi, Matteo Santucci, Gaetano Marverti, Domenico D'Arca, Lorenzo Tagliazucchi, Stefania Ferrari, Gaia Gozzi, Lorena Losi, Giusy Tassone, Stefano Mangani, Glauco Ponterini, Maria Paola Costi
Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations. Cancers 13 (9) (2021)
Giusy Tassone, Arian Kola, Daniela Valensin, Cecilia Pozzi
Dynamic Interplay between Copper Toxicity and Mitochondrial Dysfunction in Alzheimer's Disease. Life (Basel, Switzerland) 11 (5) (2021)
Carolina B Moraes, Gesa Witt, Maria Kuzikov, Bernhard Ellinger, Theodora Calogeropoulou, Kyriakos C Prousis, Stefano Mangani, Flavio Di Pisa, Giacomo Landi, Lucia Dello Iacono, Cecilia Pozzi, Lúcio Holanda Gondim de Freitas-Júnior, Bruno Dos Santos Pascoalino, Claudia P Bertolacini, Birte Behrens, Oliver Keminer, Jennifer Leu, Markus Wolf, Jeanette Reinshagen, Anabela Cordeiro-da-Silva, Nuno Santarem, Alberto Venturelli, Stephen Wrigley, Deepa Karunakaran, Bethlehem Kebede, Ina Pöhner, Wolfgang Müller, Joanna Panecka-Hofman, Rebecca C Wade, Martina Fenske, Joachim Clos, José María Alunda, María Jesús Corral, Elisa Uliassi, Maria Laura Bolognesi, Pasquale Linciano, Antonio Quotadamo, Stefania Ferrari, Matteo Santucci, Chiara Borsari, Maria Paola Costi, Sheraz Gul
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform. SLAS discovery : advancing life sciences R & D 24 (3) (2020)
David T Davies, Simon Leiris, Nicolas Sprynski, Jérôme M Castandet, Clarisse Lozano, Justine Bousquet, Magdalena Zalacain, Srinivas Vasa, Praveen K Dasari, Ramesh Pattipati, Naresh Vempala, Swetha Gujjewar, SyamKumar Godi, Raju Jallala, Rajashekar Reddy Sathyap, Narasimha A Darshanoju, Vengala R Ravu, Ramakrishna R Juventhala, Narender Pottabathini, Somesh Sharma, Srinivasu Pothukanuri, Kirsty Holden, Peter Warn, Francesca Marcoccia, Manuela Benvenuti, Cecilia Pozzi, Stefano Mangani, Jean Denis Docquier, Marc Lemonnier, Martin J Everett
ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae. ACS infectious diseases 6 (9) (2020)
Silvia Ciambellotti, Cecilia Pozzi, Stefano Mangani, Paola Turano
Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (26) (2020)
David T Davies, Simon Leiris, Magdalena Zalacain, Nicolas Sprynski, Jérôme Castandet, Justine Bousquet, Clarisse Lozano, Agustina Llanos, Laethitia Alibaud, Srinivas Vasa, Ramesh Pattipati, Ravindar Valige, Bhaskar Kummari, Srinivasu Pothukanuri, Cyntia De Piano, Ian Morrissey, Kirsty Holden, Peter Warn, Francesca Marcoccia, Manuela Benvenuti, Cecilia Pozzi, Giusy Tassone, Stefano Mangani, Jean Denis Docquier, Thomas David Pallin, Richard Elliot, Marc Lemonnier, Martin J Everett
Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii. Journal of medicinal chemistry 63 (24) (2020)
Jodie C Hamrick, Jean Denis Docquier, Tsuyoshi Uehara, Cullen L Myers, David A Six, Cassandra L Chatwin, Kaitlyn J John, Salvador F Vernacchio, Susan M Cusick, Robert E L Trout, Cecilia Pozzi, Filomena De Luca, Manuela Benvenuti, Stefano Mangani, Bin Liu, Randy W Jackson, Greg Moeck, Luigi Xerri, Christopher J Burns, Daniel C Pevear, Denis M Daigle
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy 64 (3) (2020)
Leire Iralde-Lorente, Giusy Tassone, Letizia Clementi, Lorenzo Franci, Claire C Munier, Ylenia Cau, Mattia Mori, Mario Chiariello, Adriano Angelucci, Matthew W D Perry, Cecilia Pozzi, Stefano Mangani, Maurizio Botta
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. ACS chemical biology 15 (4) (2020)
Giacomo Landi, Pasquale Linciano, Giusy Tassone, Maria Paola Costi, Stefano Mangani, Cecilia Pozzi
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor. Acta crystallographica. Section D, Structural biology 76 (Pt 6) (2020)
Daniel N Bloch, Paulina Kolkowska, Isabella Tessari, Maria Camilla Baratto, Adalgisa Sinicropi, Luigi Bubacco, Stefano Mangani, Cecilia Pozzi, Daniela Valensin, Yifat Miller
Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini. Inorganic chemistry 58 (16) (2019)
Bin Liu, Robert E Lee Trout, Guo-Hua Chu, Daniel McGarry, Randy W Jackson, Jodie C Hamrick, Denis M Daigle, Susan M Cusick, Cecilia Pozzi, Filomena De Luca, Manuela Benvenuti, Stefano Mangani, Jean Denis Docquier, William J Weiss, Daniel C Pevear, Luigi Xerri, Christopher J Burns
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections. Journal of medicinal chemistry 63 (6) (2019)
Cecilia Pozzi, Stefania Ferrari, Rosaria Luciani, Maria Paola Costi, Stefano Mangani
Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors. Molecules (Basel, Switzerland) 24 (7) (2019)
Giacomo Landi, Pasquale Linciano, Chiara Borsari, Claudia P Bertolacini, Carolina B Moraes, Anabela Cordeiro-da-Silva, Sheraz Gul, Gesa Witt, Maria Kuzikov, Maria Paola Costi, Cecilia Pozzi, Stefano Mangani
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors. ACS infectious diseases 5 (7) (2019)
Cecilia Pozzi, Stefania Ferrari, Rosaria Luciani, Giusy Tassone, Maria Paola Costi, Stefano Mangani
Structural Comparison of Enterococcus faecalis and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities. Molecules (Basel, Switzerland) 24 (7) (2019)
Cecilia Pozzi, Ludovica Lopresti, Giusy Tassone, Stefano Mangani
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS). Molecules (Basel, Switzerland) 24 (8) (2019)
Simon Leiris, Alicia Coelho, Jérôme M Castandet, Maëlle Bayet, Clarisse Lozano, Juliette Bougnon, Justine Bousquet, Martin J Everett, Marc Lemonnier, Nicolas Sprynski, Magdalena Zalacain, Thomas David Pallin, Michael C Cramp, Neil Jennings, Gilles Raphy, Mark W Jones, Ramesh Pattipati, Battu Shankar, Relangi Sivasubrahmanyam, Ashok K Soodhagani, Ramakrishna R Juventhala, Narender Pottabathini, Srinivasu Pothukanuri, Manuela Benvenuti, Cecilia Pozzi, Stefano Mangani, Filomena De Luca, Giulia Cerboni, Jean Denis Docquier, David T Davies
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model. ACS infectious diseases 5 (1) (2018)
Cecilia Pozzi, Flavio Di Pisa, Manuela Benvenuti, Stefano Mangani
The structure of the human glutaminyl cyclase-SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 23 (8) (2018)
Cecilia Pozzi, Flavio Di Pisa, Filomena De Luca, Manuela Benvenuti, Jean Denis Docquier, Stefano Mangani
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam. ChemMedChem 13 (14) (2018)
Caterina Bernacchioni, Cecilia Pozzi, Flavio Di Pisa, Stefano Mangani, Paola Turano
Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity. Chemistry (Weinheim an der Bergstrasse, Germany) 22 (45) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Cecilia Pozzi