Markus Hoffmann (M Hoffmann)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 80

Top Topics

Roux En Y Gastric Bypass

Respiratory Syndrome Coronavirus

Immune Response

Top Venues

Cellular & molecular immunology

Nature microbiology

This page only lists publications with an associated author ORCID identifier.

Publications

Lu Zhang, Alexandra Dopfer-Jablonka, Inga Nehlmeier, Amy Kempf, Luise Graichen, Noemí Calderón Hampel, Anne Cossmann, Metodi V Stankov, Gema Morillas Ramos, Sebastian R Schulz, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage. Vaccines 12 (5) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Lu Zhang, Alexandra Dopfer-Jablonka, Inga Nehlmeier, Amy Kempf, Luise Graichen, Noemí Calderón Hampel, Anne Cossmann, Metodi V Stankov, Gema Morillas Ramos, Sebastian R Schulz, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage. Vaccines 12 (5) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology (2024)
Niklas Jäger, Shreya Ahana Ayyub, Frank Peske, David Liedtke, Jens Bohne, Markus Hoffmann, Marina V Rodnina, Stefan H Pöhlmann
The Inhibition of Gag-Pol Expression by the Restriction Factor Shiftless Is Dispensable for the Restriction of HIV-1 Infection. Viruses 16 (4) (2024)
Niklas Jäger, Shreya Ahana Ayyub, Frank Peske, David Liedtke, Jens Bohne, Markus Hoffmann, Marina V Rodnina, Stefan H Pöhlmann
The Inhibition of Gag-Pol Expression by the Restriction Factor Shiftless Is Dispensable for the Restriction of HIV-1 Infection. Viruses 16 (4) (2024)
Niklas Jäger, Shreya Ahana Ayyub, Frank Peske, David Liedtke, Jens Bohne, Markus Hoffmann, Marina V Rodnina, Stefan H Pöhlmann
The Inhibition of Gag-Pol Expression by the Restriction Factor Shiftless Is Dispensable for the Restriction of HIV-1 Infection. Viruses 16 (4) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Niklas Jäger, Shreya Ahana Ayyub, Frank Peske, David Liedtke, Jens Bohne, Markus Hoffmann, Marina V Rodnina, Stefan H Pöhlmann
The Inhibition of Gag-Pol Expression by the Restriction Factor Shiftless Is Dispensable for the Restriction of HIV-1 Infection. Viruses 16 (4) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Marcel Hulst, Arie Kant, José Harders-Westerveen, Markus Hoffmann, Yajing Xie, Charlotte Laheij, Jean-Luc Murk, Wim H M Van der Poel
Cross-Reactivity of Human, Wild Boar, and Farm Animal Sera from Pre- and Post-Pandemic Periods with Alpha- and Βeta-Coronaviruses (CoV), including SARS-CoV-2. Viruses 16 (1) (2023)
Darshita Budhadev, James Hooper, Cheila Rocha, Inga Nehlmeier, Amy Madeleine Kempf, Markus Hoffmann, Nadine Krüger, Dejian Zhou, Stefan Pöhlmann, Yuan Guo
Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein. JACS Au 3 (6) (2023)
Darshita Budhadev, James Hooper, Cheila Rocha, Inga Nehlmeier, Amy Madeleine Kempf, Markus Hoffmann, Nadine Krüger, Dejian Zhou, Stefan Pöhlmann, Yuan Guo
Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein. JACS Au 3 (6) (2023)
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan H Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. PLoS biology 21 (2) (2023)
Kristin Metzdorf, Henning Jacobsen, Marina C Greweling-Pils, Markus Hoffmann, Tatjana Lüddecke, Felicitas Miller, Lars Melcher, Amy M Kempf, Inga Nehlmeier, Dunja Bruder, Marek Widera, Sandra Ciesek, Stefan H Pöhlmann, Luka Čičin Šain
TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection. Viruses 15 (2) (2023)
Kristin Metzdorf, Henning Jacobsen, Marina C Greweling-Pils, Markus Hoffmann, Tatjana Lüddecke, Felicitas Miller, Lars Melcher, Amy M Kempf, Inga Nehlmeier, Dunja Bruder, Marek Widera, Sandra Ciesek, Stefan H Pöhlmann, Luka Čičin Šain
TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection. Viruses 15 (2) (2023)
Marcel Hulst, Arie Kant, José Harders-Westerveen, Markus Hoffmann, Yajing Xie, Charlotte Laheij, Jean-Luc Murk, Wim H M Van der Poel
Cross-Reactivity of Human, Wild Boar, and Farm Animal Sera from Pre- and Post-Pandemic Periods with Alpha- and Βeta-Coronaviruses (CoV), including SARS-CoV-2. Viruses 16 (1) (2023)
Markus Hoffmann, Prerna Arora, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Sebastian R Schulz, Gema Morillas Ramos, Luis A Manthey, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann
Profound neutralization evasion and augmented host cell entry are hallmarks of the fast-spreading SARS-CoV-2 lineage XBB.1.5. Cellular & molecular immunology (2023)
Darshita Budhadev, James Hooper, Cheila Rocha, Inga Nehlmeier, Amy Madeleine Kempf, Markus Hoffmann, Nadine Krüger, Dejian Zhou, Stefan Pöhlmann, Yuan Guo
Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein. JACS Au 3 (6) (2023)
Inga Nehlmeier, Amy Kempf, Prerna Arora, Anne Cossmann, Alexandra Dopfer-Jablonka, Metodi V Stankov, Sebastian R Schulz, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
Host cell entry and neutralisation sensitivity of the SARS-CoV-2 XBB.1.16 lineage. Cellular & molecular immunology (2023)
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan H Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. PLoS biology 21 (2) (2023)
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan H Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. PLoS biology 21 (2) (2023)
Marcel Hulst, Arie Kant, José Harders-Westerveen, Markus Hoffmann, Yajing Xie, Charlotte Laheij, Jean-Luc Murk, Wim H M Van der Poel
Cross-Reactivity of Human, Wild Boar, and Farm Animal Sera from Pre- and Post-Pandemic Periods with Alpha- and Βeta-Coronaviruses (CoV), including SARS-CoV-2. Viruses 16 (1) (2023)
Marcel Hulst, Arie Kant, José Harders-Westerveen, Markus Hoffmann, Yajing Xie, Charlotte Laheij, Jean-Luc Murk, Wim H M Van der Poel
Cross-Reactivity of Human, Wild Boar, and Farm Animal Sera from Pre- and Post-Pandemic Periods with Alpha- and Βeta-Coronaviruses (CoV), including SARS-CoV-2. Viruses 16 (1) (2023)
Marcel Hulst, Arie Kant, José Harders-Westerveen, Markus Hoffmann, Yajing Xie, Charlotte Laheij, Jean-Luc Murk, Wim H M Van der Poel
Cross-Reactivity of Human, Wild Boar, and Farm Animal Sera from Pre- and Post-Pandemic Periods with Alpha- and Βeta-Coronaviruses (CoV), including SARS-CoV-2. Viruses 16 (1) (2023)
Markus Hoffmann, Prerna Arora, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Sebastian R Schulz, Gema Morillas Ramos, Luis A Manthey, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann
Profound neutralization evasion and augmented host cell entry are hallmarks of the fast-spreading SARS-CoV-2 lineage XBB.1.5. Cellular & molecular immunology (2023)
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan H Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. PLoS biology 21 (2) (2023)
Kristin Metzdorf, Henning Jacobsen, Marina C Greweling-Pils, Markus Hoffmann, Tatjana Lüddecke, Felicitas Miller, Lars Melcher, Amy M Kempf, Inga Nehlmeier, Dunja Bruder, Marek Widera, Sandra Ciesek, Stefan H Pöhlmann, Luka Čičin Šain
TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection. Viruses 15 (2) (2023)
Inga Nehlmeier, Amy Kempf, Prerna Arora, Anne Cossmann, Alexandra Dopfer-Jablonka, Metodi V Stankov, Sebastian R Schulz, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
Host cell entry and neutralisation sensitivity of the SARS-CoV-2 XBB.1.16 lineage. Cellular & molecular immunology (2023)
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan H Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. PLoS biology 21 (2) (2023)
Markus Hoffmann, Prerna Arora, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Sebastian R Schulz, Gema Morillas Ramos, Luis A Manthey, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann
Profound neutralization evasion and augmented host cell entry are hallmarks of the fast-spreading SARS-CoV-2 lineage XBB.1.5. Cellular & molecular immunology (2023)
Markus Hoffmann, Lok-Yin Roy Wong, Prerna Arora, Lu Zhang, Cheila Rocha, Abby Odle, Inga Nehlmeier, Amy Kempf, Anja Richter, Nico Joël Halwe, Jacob Schön, Lorenz Ulrich, Donata Hoffmann, Martin Beer, Christian Drosten, Stanley Perlman, Stefan H Pöhlmann
Omicron subvariant BA.5 efficiently infects lung cells. Nature communications 14 (1) (2023)
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan H Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. PLoS biology 21 (2) (2023)
Prerna Arora, Anzhalika Sidarovich, Luise Graichen, Bojan Hörnich, Alexander S Hahn, Markus Hoffmann, Stefan H Pöhlmann
Functional analysis of polymorphisms at the S1/S2 site of SARS-CoV-2 spike protein. PloS one 17 (3) (2022)
Lukas Wettstein, Philip Maximilian Knaff, Christian Kersten, Patrick Müller, Tatjana Weil, Carina Conzelmann, Janis A Müller, Maximilian Brückner, Markus Hoffmann, Stefan H Pöhlmann, Tanja Schirmeister, Katharina Landfester, Jan Münch, Volker Mailänder
Peptidomimetic inhibitors of TMPRSS2 block SARS-CoV-2 infection in cell culture. Communications biology 5 (1) (2022)
Markus Hoffmann, Stefan H Pöhlmann
Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1. Cell research 32 (1) (2022)
Markus Hoffmann, Lu Zhang, Stefan H Pöhlmann
Omicron: Master of immune evasion maintains robust ACE2 binding. Signal transduction and targeted therapy 7 (1) (2022)
Niklas Jäger, Shreya Ahana Ayyub, Natalia Korniy, Frank Peske, Markus Hoffmann, Marina V Rodnina, Stefan H Pöhlmann
Mutagenic Analysis of the HIV Restriction Factor Shiftless. Viruses 14 (7) (2022)
Prerna Arora, Amy Kempf, Inga Nehlmeier, Luise Graichen, Martin S Winkler, Martin Lier, Sebastian R Schulz, Hans-Martin Jäck, Stefan H Pöhlmann, Markus Hoffmann
No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2. Cellular & molecular immunology 19 (3) (2022)
Niklas Jäger, Markus Hoffmann, Stefan H Pöhlmann, Nadine Krüger
Nafamostat-Mediated Inhibition of SARS-CoV-2 Ribosomal Frameshifting Is Insufficient to Impair Viral Replication in Vero Cells. Comment on Munshi et al. Identifying Inhibitors of -1 Programmed Ribosomal Frameshifting in a Broad Spectrum of Coronaviruses. Viruses 2022, 14 , 177. Viruses 14 (7) (2022)
Markus Hoffmann, Anzhalika Sidarovich, Prerna Arora, Nadine Krüger, Inga Nehlmeier, Amy Kempf, Luise Graichen, Martin S Winkler, Daniela Niemeyer, Christine Goffinet, Christian Drosten, Sebastian Schulz, Hans-Martin Jäck, Stefan H Pöhlmann
Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy. mBio 13 (3) (2022)
Markus Hoffmann, Yeonhwa Jin, Stefan H Pöhlmann
Publisher Correction: Dalbavancin: novel candidate for COVID-19 treatment. Cell research (2022)
Prerna Arora, Lu Zhang, Cheila Rocha, Luise Graichen, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Gema Morillas Ramos, Eva Baier, Bjoern Tampe, Onnen Moerer, Steffen Dickel, Martin S Winkler, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant. International journal of molecular sciences 23 (22) (2022)
Yeonsu Kim, Xiaoyan Zheng, Kathrin Eschke, M Zeeshan Chaudhry, Federico Bertoglio, Adriana Tomić, Astrid Krmpotić, Markus Hoffmann, Yotam Bar-On, Julia Boehme, Dunja Bruder, Thomas Ebensen, Linda Brunotte, Stephan Ludwig, Martin Messerle, Carlos Guzman, Ofer Mandelboim, Michael Hust, Stefan H Pöhlmann, Stipan Jonjić, Luka Čičin Šain
MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination. Cellular & molecular immunology 19 (2) (2022)
Prerna Arora, Amy Kempf, Inga Nehlmeier, Luise Graichen, Sebastian R Schulz, Anne Cossmann, Alexandra Dopfer-Jablonka, Martin S Winkler, Hans-Martin Jäck, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
Efficient antibody evasion but reduced ACE2 binding by the emerging SARS-CoV-2 variant B.1.640.2. Cellular & molecular immunology 19 (9) (2022)
Kritika Khanna, Wilfred W Raymond, Jing Jin, Annabelle R Charbit, Irina Gitlin, Monica Tang, Adam D Werts, Edward G Barrett, Jason M Cox, Sharla M Birch, Rachel Martinelli, Hannah S Sperber, Sergej Franz, Thomas Duff, Markus Hoffmann, Anne Marie Healy, Stefan Oscarson, Stefan Pöhlmann, Satish K Pillai, Graham Simmons, John V Fahy
Exploring antiviral and anti-inflammatory effects of thiol drugs in COVID-19. American journal of physiology. Lung cellular and molecular physiology 323 (3) (2022)
G M N Behrens, A Cossmann, Markus Hoffmann
Omicron spike protein: a clue for viral entry and immune evasion. Signal transduction and targeted therapy 7 (1) (2022)
Georg Martin Norbert Behrens, Joana Barros-Martins, Anne Cossmann, Gema Morillas Ramos, Metodi V Stankov, Ivan Odak, Alexandra Dopfer-Jablonka, Laura Hetzel, Miriam Köhler, Gwendolyn Patzer, Christoph Binz, Christiane Ritter, Michaela Friedrichsen, Christian R Schultze-Florey, Inga Ravens, Stefanie Willenzon, Anja Bubke, Jasmin Ristenpart, Anika Janssen, George Liam Ssebyatika, Verena Krähling, Günter Bernhardt, Markus Hoffmann, Stefan Pöhlmann, Thomas Krey, Berislav Bosnjak, Swantje I Hammerschmidt, Reinhold Förster
BNT162b2-boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19. Nature communications 13 (1) (2022)
Markus Hoffmann, Prerna Arora, Stefan H Pöhlmann
Understanding Omicron: Transmissibility, immune evasion and antiviral intervention. Clinical and translational medicine 12 (5) (2022)
Lukas Wettstein, Tatjana Weil, Carina Conzelmann, Janis A Müller, Ruediger Gross, Maximilian Hirschenberger, Alina Seidel, Susanne Klute, Fabian Zech, Caterina Prelli Bozzo, Nico Preising, Giorgio Fois, Robin Lochbaum, Philip Maximilian Knaff, Volker Mailänder, Ludger Ständker, Dietmar Rudolf Thal, Christian Schumann, Steffen Stenger, Alexander Kleger, Guenter Lochnit, Benjamin Mayer, Yasser B Ruiz-Blanco, Markus Hoffmann, Konstantin Maria Johannes Sparrer, Stefan H Pöhlmann, Elsa Sanchez-Garcia, Frank Kirchhoff, Manfred Frick, Jan Münch
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection. Nature communications 12 (1) (2021)
Markus Hoffmann, Yeonhwa Jin, Stefan H Pöhlmann
Dalbavancin: novel candidate for COVID-19 treatment. Cell research 31 (3) (2021)
Tim Hempel, Katarina Elez, Nadine Krüger, Lluís Raich, Jonathan H Shrimp, Olga Danov, Danny Jonigk, Armin Braun, Min Shen, Matthew D Hall, Stefan Pöhlmann, Markus Hoffmann, Frank Noé
Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties. Chemical science 12 (38) (2021)
Markus Hoffmann, Stefan H Pöhlmann
How SARS-CoV-2 makes the cut. Nature microbiology 6 (7) (2021)
Dennis Lapuente, Jana Fuchs, Jonas Willar, Ana Vieira Antão, Valentina Eberlein, Nadja Uhlig, Leila Issmail, Anna Schmidt, Friederike Oltmanns, Antonia Sophia Peter, Sandra Mueller-Schmucker, Pascal Irrgang, Kirsten Fraedrich, Andrea Cara, Markus Hoffmann, Stefan H Pöhlmann, Armin Ensser, Cordula Pertl, Torsten Willert, Christian Thirion, Thomas Grunwald, Klaus Überla, Matthias Tenbusch
Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization. Nature communications 12 (1) (2021)
Fabian Zech, Daniel Schniertshauer, Christoph Jung, Alexandra Herrmann, Arne Cordsmeier, Qinya Xie, Rayhane Nchioua, Caterina Prelli Bozzo, Meta Volcic, Lennart Koepke, Janis A Müller, Jana Krüger, Sandra Heller, Steffen Stenger, Markus Hoffmann, Stefan H Pöhlmann, Alexander Kleger, Timo Jacob, Karl Klaus Conzelmann, Armin Ensser, Konstantin Maria Johannes Sparrer, Frank Kirchhoff
Spike residue 403 affects binding of coronavirus spikes to human ACE2. Nature communications 12 (1) (2021)
Prerna Arora, Cheila Rocha, Amy Kempf, Inga Nehlmeier, Luise Graichen, Martin S Winkler, Martin Lier, Sebastian R Schulz, Hans-Martin Jäck, Anne Cossmann, Metodi V Stankov, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency. Cellular & molecular immunology 18 (12) (2021)
Joana Barros-Martins, Swantje I Hammerschmidt, Anne Cossmann, Ivan Odak, Metodi V Stankov, Gema Morillas Ramos, Alexandra Dopfer-Jablonka, Annika Heidemann, Christiane Ritter, Michaela Friedrichsen, Christian R Schultze-Florey, Inga Ravens, Stefanie Willenzon, Anja Bubke, Jasmin Ristenpart, Anika Janssen, George Ssebyatika, Günter Bernhardt, Jan Münch, Markus Hoffmann, Stefan H Pöhlmann, Thomas Krey, Berislav Bosnjak, Reinhold Förster, Georg Martin Norbert Behrens
Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Nature medicine 27 (9) (2021)
Swantje I Hammerschmidt, Berislav Bosnjak, Günter Bernhardt, Michaela Friedrichsen, Inga Ravens, Alexandra Dopfer-Jablonka, Markus Hoffmann, Stefan H Pöhlmann, Georg Martin Norbert Behrens, Reinhold Förster
Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination. Cellular & molecular immunology 18 (10) (2021)
Fiona Tea, Alberto Ospina Stella, Anupriya Aggarwal, David R Darley, Deepti Pilli, Daniele Vitale, Vera Merheb, Fiona X Z Lee, Philip Cunningham, Gregory J Walker, Christina Fichter, David A Brown, William D Rawlinson, Sonia R Isaacs, Vennila Mathivanan, Markus Hoffmann, Stefan H Pöhlmann, Ohan Mazigi, Daniel Christ, Dominic E Dwyer, Rebecca J Rockett, Vitali Sintchenko, Veronica C Hoad, David O Irving, Gregory J Dore, Iain B Gosbell, Anthony D Kelleher, Gail V Matthews, Fabienne Brilot, Stuart G Turville
SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants. PLoS medicine 18 (7) (2021)
Prerna Arora, Stefan H Pöhlmann, Markus Hoffmann
Mutation D614G increases SARS-CoV-2 transmission. Signal transduction and targeted therapy 6 (1) (2021)
Manon Laporte, Valerie Raeymaekers, Ria Van Berwaer, Julie Vandeput, Isabel Marchand-Casas, Hendrik-Jan Thibaut, Dominique Van Looveren, Katleen Martens, Markus Hoffmann, Piet Maes, Stefan H Pöhlmann, Lieve Naesens, Annelies Stevaert
The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways. PLoS pathogens 17 (4) (2021)
Prerna Arora, Amy Kempf, Inga Nehlmeier, Luise Graichen, Anzhalika Sidarovich, Martin S Winkler, Sebastian R Schulz, Hans-Martin Jäck, Metodi V Stankov, Georg Martin Norbert Behrens, Stefan H Pöhlmann, Markus Hoffmann
Delta variant (B.1.617.2) sublineages do not show increased neutralization resistance. Cellular & molecular immunology 18 (11) (2021)
Matthew Mahoney, Vishnu C Damalanka, Michael A Tartell, Dong Hee Chung, André Luiz Lourenço, Dustin Pwee, Anne E Mayer Bridwell, Markus Hoffmann, Jorine Voss, Partha Karmakar, Nurit P Azouz, Andrea M Klingler, Paul W Rothlauf, Cassandra E Thompson, Melody Lee, Lidija Klampfer, Christina L Stallings, Marc E Rothenberg, Stefan H Pöhlmann, Sean P J Whelan, Anthony J O'Donoghue, Charles S Craik, James W Janetka
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proceedings of the National Academy of Sciences of the United States of America 118 (43) (2021)
Nadine Krüger, Cheila Rocha, Sandra Runft, Johannes Krüger, Iris Färber, Federico Armando, Eva Leitzen, Graham Brogden, Gisa Gerold, Stefan H Pöhlmann, Markus Hoffmann, Wolfgang Baumgärtner
The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection. International journal of molecular sciences 22 (19) (2021)
Tim Hempel, Lluís Raich, Simon Olsson, Nurit P Azouz, Andrea M Klingler, Markus Hoffmann, Stefan H Pöhlmann, Xiaoting Chen, Frank Noé
Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat. Chemical science 12 (3) (2020)
Stephanie Pfaender, Katrina B Mar, Eleftherios Michailidis, Annika Kratzel, Ian N Boys, Philip Vkovski, Wenchun Fan, Jenna N Kelly, Dagny Hirt, Nadine Ebert, Hanspeter Stalder, Hannah Kleine-Weber, Markus Hoffmann, Hans-Heinrich Hoffmann, Mohsan Saeed, Ronald Dijkman, Eike Steinmann, Mary Wight-Carter, Matthew B McDougal, Natasha W Hanners, Stefan H Pöhlmann, Thomas Gallagher, Daniel Todt, Gert Zimmer, Charles M Rice, John W Schoggins, Volker Thiel
LY6E impairs coronavirus fusion and confers immune control of viral disease. Nature microbiology 5 (11) (2020)
Markus Hoffmann, Simon Schroeder, Hannah Kleine-Weber, Marcel A Müller, Christian Drosten, Stefan H Pöhlmann
Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19. Antimicrobial agents and chemotherapy 64 (6) (2020)
Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Alexander Prokscha, Hassan Y Naim, Marcel Alexander Müller, Christian Drosten, Stefan H Pöhlmann, Markus Hoffmann
Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus. Emerging microbes & infections 9 (1) (2020)
Berislav Bosnjak, Saskia Catherina Stein, Stefanie Willenzon, Anne Katrin Cordes, Wolfram Puppe, Günter Bernhardt, Inga Ravens, Christiane Ritter, Christian R Schultze-Florey, Nina Gödecke, Jörg Martens, Hannah Kleine-Weber, Markus Hoffmann, Anne Cossmann, Mustafa Yilmaz, Isabelle Pink, Marius M Hoeper, Georg M N Behrens, Stefan Pöhlmann, Rainer Blasczyk, Thomas F Schulz, Reinhold Förster
Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods. Cellular & molecular immunology 18 (4) (2020)
Markus Hoffmann, Kirstin Mösbauer, Heike Hofmann-Winkler, Artur Kaul, Hannah Kleine-Weber, Nadine Krüger, Nils C Gassen, Marcel Alexander Müller, Christian Drosten, Stefan H Pöhlmann
Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2. Nature 585 (7826) (2020)
Sarah Hüttl, Markus Hoffmann, Torsten Steinmetzer, Christian Sauder, Nadine Krüger
The Amino Acid at Position 8 of the Proteolytic Cleavage Site of the Mumps Virus Fusion Protein Affects Viral Proteolysis and Fusogenicity. Journal of virology 94 (22) (2020)
Markus Hoffmann, Inga Nehlmeier, Constantin Brinkmann, Verena Krähling, Laura Behner, Anna-Sophie Moldenhauer, Nadine Krüger, Julia Nehls, Michael Schindler, Thomas Hoenen, Andrea Maisner, Stephan Becker, Stefan H Pöhlmann
Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells. Journal of virology 93 (3) (2019)
Michael Winkler, Sabine Gärtner, Lara Markus, Markus Hoffmann, Inga Nehlmeier, Michael Krawczak, Ulrike Sauermann, Stefan H Pöhlmann
Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques. PloS one 14 (11) (2019)
Kathleen Voigt, Markus Hoffmann, Jan Felix Drexler, Marcel Alexander Müller, Christian Drosten, Georg Herrler, Nadine Krüger
Fusogenicity of the Ghana Virus (Henipavirus: Ghanaian bat henipavirus) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein. Viruses 11 (9) (2019)
Hannah Kleine-Weber, Mahmoud Tarek Elzayat, Lingshu Wang, Barney S Graham, Marcel A Müller, Christian Drosten, Stefan H Pöhlmann, Markus Hoffmann
Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization. Journal of virology 93 (2) (2019)
Markus Hoffmann, Enrika Schütze, Andreas Bernhard, Lennart Schlaphoff, Artur Kaul, Sandra Schöniger, Stefan H Pöhlmann
Disease Manifestation and Viral Sequences in a Bonobo More Than 30 Years after Papillomavirus Infection. Pathogens (Basel, Switzerland) 8 (1) (2019)
Markus Hoffmann, Svenja Victoria Kaufmann, Carina Fischer, Wiebke Maurer, Anna-Sophie Moldenhauer, Stefan H Pöhlmann
Analysis of Resistance of Ebola Virus Glycoprotein-Driven Entry Against MDL28170, An Inhibitor of Cysteine Cathepsins. Pathogens (Basel, Switzerland) 8 (4) (2019)
Hannah Kleine-Weber, Mahmoud Tarek Elzayat, Markus Hoffmann, Stefan H Pöhlmann
Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein. Scientific reports 8 (1) (2018)