Alexander Kleger

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 52

Top Venues

United European gastroenterology journal

Cells

BMC biology

Cancers

This page only lists publications with an associated author ORCID identifier.

Publications

Lukas Perkhofer, Katja Kilani, Ägädius Wieser, Thomas Seufferlein, Pauline Kleger, Martin Mueller, Alexander Kleger
SARS-Cov-2 vaccination is safe in autoimmune pancreatitis patients. United European gastroenterology journal 12 (1) (2024)
Lukas Perkhofer, Katja Kilani, Ägädius Wieser, Thomas Seufferlein, Pauline Kleger, Martin Mueller, Alexander Kleger
SARS-Cov-2 vaccination is safe in autoimmune pancreatitis patients. United European gastroenterology journal 12 (1) (2024)
Lukas Perkhofer, Katja Kilani, Ägädius Wieser, Thomas Seufferlein, Pauline Kleger, Martin Mueller, Alexander Kleger
SARS-Cov-2 vaccination is safe in autoimmune pancreatitis patients. United European gastroenterology journal 12 (1) (2024)
Ninel Azoitei, Sandra Heller, Alexander Kleger
Pandemic punch: SARS-CoV-2 hits pancreas. Signal transduction and targeted therapy 9 (1) (2024)
Ninel Azoitei, Sandra Heller, Alexander Kleger
Pandemic punch: SARS-CoV-2 hits pancreas. Signal transduction and targeted therapy 9 (1) (2024)
Lukas Perkhofer, Katja Kilani, Ägädius Wieser, Thomas Seufferlein, Pauline Kleger, Martin Mueller, Alexander Kleger
SARS-Cov-2 vaccination is safe in autoimmune pancreatitis patients. United European gastroenterology journal (2024)
Lukas Perkhofer, Katja Kilani, Ägädius Wieser, Thomas Seufferlein, Pauline Kleger, Martin Mueller, Alexander Kleger
SARS-Cov-2 vaccination is safe in autoimmune pancreatitis patients. United European gastroenterology journal 12 (1) (2024)
Ninel Azoitei, Sandra Heller, Alexander Kleger
Pandemic punch: SARS-CoV-2 hits pancreas. Signal transduction and targeted therapy 9 (1) (2024)
Lukas Perkhofer, Katja Kilani, Ägädius Wieser, Thomas Seufferlein, Pauline Kleger, Martin Mueller, Alexander Kleger
SARS-Cov-2 vaccination is safe in autoimmune pancreatitis patients. United European gastroenterology journal 12 (1) (2024)
Ninel Azoitei, Sandra Heller, Alexander Kleger
Pandemic punch: SARS-CoV-2 hits pancreas. Signal transduction and targeted therapy 9 (1) (2024)
Fatemeh Navaee, Niloofar Khornian, David Longet, Sarah Heub, Stephanie Boder-Pasche, Gilles Weder, Alexander Kleger, Philippe Renaud, Thomas Braschler
A Three-Dimensional Engineered Cardiac In Vitro Model: Controlled Alignment of Cardiomyocytes in 3D Microphysiological Systems. Cells 12 (4) (2023)
Fatemeh Navaee, Philippe Renaud, Alexander Kleger, Thomas Braschler
Highly Efficient Cardiac Differentiation and Maintenance by Thrombin-Coagulated Fibrin Hydrogels Enriched with Decellularized Porcine Heart Extracellular Matrix. International journal of molecular sciences 24 (3) (2023)
Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Ingo Burtscher, Chantal Allgöwer, Medhanie Mulaw, Friedemann Zengerling, Cagatay Günes, Heiko Lickert, Vincent M Christoffels, Stefan Liebau, Martin Wagner, Thomas Seufferlein, Christian Bolenz, Anne M Moon, Lukas Perkhofer, Alexander Kleger
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration. BMC biology 21 (1) (2023)
Fatemeh Navaee, Philippe Renaud, Niccolò Piacentini, Mathilde Durand, Dara Zaman Bayat, Diane Ledroit, Sarah Heub, Stephanie Boder-Pasche, Alexander Kleger, Thomas Braschler, Gilles Weder
Toward a Physiologically Relevant 3D Helicoidal-Oriented Cardiac Model: Simultaneous Application of Mechanical Stimulation and Surface Topography. Bioengineering (Basel, Switzerland) 10 (2) (2023)
Fatemeh Navaee, Philippe Renaud, Niccolò Piacentini, Mathilde Durand, Dara Zaman Bayat, Diane Ledroit, Sarah Heub, Stephanie Boder-Pasche, Alexander Kleger, Thomas Braschler, Gilles Weder
Toward a Physiologically Relevant 3D Helicoidal-Oriented Cardiac Model: Simultaneous Application of Mechanical Stimulation and Surface Topography. Bioengineering (Basel, Switzerland) 10 (2) (2023)
Fatemeh Navaee, Philippe Renaud, Alexander Kleger, Thomas Braschler
Highly Efficient Cardiac Differentiation and Maintenance by Thrombin-Coagulated Fibrin Hydrogels Enriched with Decellularized Porcine Heart Extracellular Matrix. International journal of molecular sciences 24 (3) (2023)
Fatemeh Navaee, Niloofar Khornian, David Longet, Sarah Heub, Stephanie Boder-Pasche, Gilles Weder, Alexander Kleger, Philippe Renaud, Thomas Braschler
A Three-Dimensional Engineered Cardiac In Vitro Model: Controlled Alignment of Cardiomyocytes in 3D Microphysiological Systems. Cells 12 (4) (2023)
Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Ingo Burtscher, Chantal Allgöwer, Medhanie Mulaw, Friedemann Zengerling, Cagatay Günes, Heiko Lickert, Vincent M Christoffels, Stefan Liebau, Martin Wagner, Thomas Seufferlein, Christian Bolenz, Anne M Moon, Lukas Perkhofer, Alexander Kleger
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration. BMC biology 21 (1) (2023)
Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Ingo Burtscher, Chantal Allgöwer, Medhanie Mulaw, Friedemann Zengerling, Cagatay Günes, Heiko Lickert, Vincent M Christoffels, Stefan Liebau, Martin Wagner, Thomas Seufferlein, Christian Bolenz, Anne M Moon, Lukas Perkhofer, Alexander Kleger
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration. BMC biology 21 (1) (2023)
Fatemeh Navaee, Philippe Renaud, Alexander Kleger, Thomas Braschler
Highly Efficient Cardiac Differentiation and Maintenance by Thrombin-Coagulated Fibrin Hydrogels Enriched with Decellularized Porcine Heart Extracellular Matrix. International journal of molecular sciences 24 (3) (2023)
Fatemeh Navaee, Philippe Renaud, Niccolò Piacentini, Mathilde Durand, Dara Zaman Bayat, Diane Ledroit, Sarah Heub, Stephanie Boder-Pasche, Alexander Kleger, Thomas Braschler, Gilles Weder
Toward a Physiologically Relevant 3D Helicoidal-Oriented Cardiac Model: Simultaneous Application of Mechanical Stimulation and Surface Topography. Bioengineering (Basel, Switzerland) 10 (2) (2023)
Jana Krüger, Anja Pfaus, Markus Breunig, Chantal Allgöwer, Lucas Schulte, Jessica Merkle, Medhanie A Mulaw, Nnamdi Okeke, Michael Karl Melzer, Clara Morgenstern, Ninel Azoitei, Thomas Seufferlein, Thomas Fe Barth, Reiner Siebert, Meike Hohwieler, Alexander Kleger
DNA methylation-associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis. The Journal of pathology (2023)
Michael Karl Melzer, Silvia Schirge, Johann Gout, Frank Arnold, Dharini Srinivasan, Ingo Burtscher, Chantal Allgöwer, Medhanie Mulaw, Friedemann Zengerling, Cagatay Günes, Heiko Lickert, Vincent M Christoffels, Stefan Liebau, Martin Wagner, Thomas Seufferlein, Christian Bolenz, Anne M Moon, Lukas Perkhofer, Alexander Kleger
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration. BMC biology 21 (1) (2023)
Fatemeh Navaee, Niloofar Khornian, David Longet, Sarah Heub, Stephanie Boder-Pasche, Gilles Weder, Alexander Kleger, Philippe Renaud, Thomas Braschler
A Three-Dimensional Engineered Cardiac In Vitro Model: Controlled Alignment of Cardiomyocytes in 3D Microphysiological Systems. Cells 12 (4) (2023)
Michael Karl Melzer, Markus Breunig, Frank Arnold, Felix Wezel, Anca Azoitei, Elodie Roger, Jana Krüger, Jessica Merkle, Lena Schütte, Yazid Resheq, Mark Hänle, Viktor Zehe, Friedemann Zengerling, Ninel Azoitei, Lukas Klein, Frederike Penz, Shiv K Singh, Thomas Seufferlein, Meike Hohwieler, Christian Bolenz, Cagatay Günes, Johann Gout, Alexander Kleger
Organoids at the PUB: The Porcine Urinary Bladder Serves as a Pancreatic Niche for Advanced Cancer Modeling. Advanced healthcare materials 11 (11) (2022)
Lap Kwan Chan, Miltiadis Tsesmelis, Melanie Gerstenlauer, Frank Leithäuser, Alexander Kleger, Lukas Daniel Frick, Harald Jacob Maier, Thomas Wirth
Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis. Communications biology 5 (1) (2022)
Viktoria Hentschel, Benjamin Michael Walter, Noemi Harder, Frank Arnold, Thomas Seufferlein, Martin Wagner, Martin Müller, Alexander Kleger
Microbial Spectra and Clinical Outcomes from Endoscopically Drained Pancreatic Fluid Collections: A Descriptive Cohort Study. Antibiotics (Basel, Switzerland) 11 (3) (2022)
Ruediger Gross, Alexander Kleger
COVID-19 and diabetes - where are we now? Nature metabolism (2022)
Jana Krüger, Markus Breunig, Lino Pascal Pasquini, Mareen Morawe, Alexander Groß, Frank Arnold, Ronan Russell, Thomas Seufferlein, Ninel Azoitei, Hans Armin Kestler, Cécile Julier, Sandra Heller, Meike Hohwieler, Alexander Kleger
Functional Genomic Screening in Human Pluripotent Stem Cells Reveals New Roadblocks in Early Pancreatic Endoderm Formation. Cells 11 (3) (2022)
Michael Karl Melzer, Alexander Kleger
Acute pancreatitis: Murine model systems unravel disease-modifying genes with potential implications for diagnostics and patient stratification. United European gastroenterology journal 10 (7) (2022)
Viktoria Hentschel, Jennice Beckmann, Wolfgang Kratzer, Frank Arnold, Thomas Seufferlein, Benjamin Walter, Alexander Kleger, Martin Müller
A Systematic Comparative Study on the Diagnostic Value of Transabdominal Ultrasound in Patients with Pancreatic Cystic Lesions. Journal of clinical medicine 11 (20) (2022)
Jessica Merkle, Markus Breunig, Maximilian Schmid, Chantal Allgöwer, Jana Krüger, Michael Karl Melzer, Susanne Bens, Reiner Siebert, Lukas Perkhofer, Ninel Azoitei, Thomas Seufferlein, Sandra Heller, Matthias Meier, Martin Müller, Alexander Kleger, Meike Hohwieler
CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome. Cancers 13 (20) (2021)
Johanna Backhus, Christian Neumann, Lukas Perkhofer, Lucas A Schulte, Benjamin Mayer, Thomas Seufferlein, Martin Müller, Alexander Kleger
A Follow-Up Study of a European IgG4-Related Disease Cohort Treated with Rituximab. Journal of clinical medicine 10 (6) (2021)
Viktoria Hentschel, Frank Arnold, Thomas Seufferlein, Ninel Azoitei, Alexander Kleger, Martin Müller
Enteropathogenic Infections: Organoids Go Bacterial. Stem cells international 2021 (2021)
Lukas Wettstein, Tatjana Weil, Carina Conzelmann, Janis A Müller, Ruediger Gross, Maximilian Hirschenberger, Alina Seidel, Susanne Klute, Fabian Zech, Caterina Prelli Bozzo, Nico Preising, Giorgio Fois, Robin Lochbaum, Philip Maximilian Knaff, Volker Mailänder, Ludger Ständker, Dietmar Rudolf Thal, Christian Schumann, Steffen Stenger, Alexander Kleger, Guenter Lochnit, Benjamin Mayer, Yasser B Ruiz-Blanco, Markus Hoffmann, Konstantin Maria Johannes Sparrer, Stefan H Pöhlmann, Elsa Sanchez-Garcia, Frank Kirchhoff, Manfred Frick, Jan Münch
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection. Nature communications 12 (1) (2021)
Caterina Prelli Bozzo, Rayhane Nchioua, Meta Volcic, Lennart Koepke, Jana Krüger, Desiree Schütz, Sandra Heller, Christina M Stürzel, Dorota Kmiec, Carina Conzelmann, Janis A Müller, Fabian Zech, Elisabeth Braun, Ruediger Gross, Lukas Wettstein, Tatjana Weil, Johanna Weiß, Federica Diofano, Armando Alexei Rodríguez, Sebastian Wiese, Daniel Sauter, Jan Münch, Christine Goffinet, Alberto Catanese, Michael Schön, Tobias M Böckers, Steffen Stenger, Kei Sato, Steffen Just, Alexander Kleger, Konstantin Maria Johannes Sparrer, Frank Kirchhoff
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro. Nature communications 12 (1) (2021)
Sandra Heller, Zhijian Li, Qiong Lin, Ryan Geusz, Markus Breunig, Meike Hohwieler, Xi Zhang, Gopika G Nair, Thomas Seufferlein, Matthias Hebrok, Maike Sander, Cécile Julier, Alexander Kleger, Ivan G Costa
Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation. Communications biology 4 (1) (2021)
Anne Philippi, Sandra Heller, Ivan G Costa, Valérie Senée, Markus Breunig, Zhijian Li, Sungjin Kwon, Ronan Russell, Anett Illing, Qiong Lin, Meike Hohwieler, Anne Degavre, Pierre A Zalloua, Stefan Liebau, Michael K Schuster, Johannes Krumm, Xi Zhang, Ryan Geusz, Jacqueline R Benthuysen, Allen Wang, Joshua Chiou, Kyle J Gaulton, Heike Neubauer, Eric Simon, Thomas Klein, Martin Wagner, Gopika Nair, Céline Besse, Claire Dandine-Roulland, Robert Olaso, Jean-François Deleuze, Bernhard Kuster, Matthias Hebrok, Thomas Seufferlein, Bjoern Gaertner, Bernhard Otto Boehm, Franz Oswald, Marc Nicolino, Cécile Julier, Alexander Kleger
Mutations and variants of ONECUT1 in diabetes. Nature medicine 27 (11) (2021)
Fabian Zech, Daniel Schniertshauer, Christoph Jung, Alexandra Herrmann, Arne Cordsmeier, Qinya Xie, Rayhane Nchioua, Caterina Prelli Bozzo, Meta Volcic, Lennart Koepke, Janis A Müller, Jana Krüger, Sandra Heller, Steffen Stenger, Markus Hoffmann, Stefan H Pöhlmann, Alexander Kleger, Timo Jacob, Karl Klaus Conzelmann, Armin Ensser, Konstantin Maria Johannes Sparrer, Frank Kirchhoff
Spike residue 403 affects binding of coronavirus spikes to human ACE2. Nature communications 12 (1) (2021)
Karolin Walter, Eva Rodriguez-Aznar, Monica S Ventura Ferreira, Pierre-Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen, Laura Lerma, Nora Daiss, Lucas-Alexander Schulte, Zeynab Najafova, Frank Arnold, Valentyn Usachov, Ninel Azoitei, Mert Erkan, Andre Lechel, Tim Henrik Brümmendorf, Thomas Seufferlein, Alexander Kleger, Enrique Tabarés, Cagatay Gunes, Steven A Johnsen, Fabian Beier, Bruno Sainz, Patrick Christian Hermann
Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells. Cancers 13 (13) (2021)
Joshua Chiou, Ryan J Geusz, Mei-Lin Okino, Jee Yun Han, Michael Miller, Rebecca Melton, Elisha Beebe, Paola Benaglio, Serina Huang, Katha Korgaonkar, Sandra Heller, Alexander Kleger, Sebastian Preissl, David U Gorkin, Maike Sander, Kyle J Gaulton
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics. Nature 594 (7863) (2021)
Alica K Beutel, Lena Schütte, Jeanette Scheible, Elodie Roger, Martin Müller, Lukas Perkhofer, Annika M T U Kestler, Johann M Kraus, Hans Armin Kestler, Thomas F E Barth, Johannes Lemke, Marko Kornmann, Thomas Jens Ettrich, Johann Gout, Thomas Seufferlein, Alexander Kleger
A Prospective Feasibility Trial to Challenge Patient-Derived Pancreatic Cancer Organoids in Predicting Treatment Response. Cancers 13 (11) (2021)
Lukas Perkhofer, Talia Golan, Pieter-Jan Cuyle, Tamara Matysiak-Budnik, Jean-Luc Van Laethem, Teresa Macarulla, Estelle Cauchin, Alexander Kleger, Alica K Beutel, Johann Gout, Albrecht Stenzinger, Eric Van Cutsem, Joaquim Bellmunt, Pascal Hammel, Eileen M O'Reilly, Thomas Seufferlein
Targeting DNA Damage Repair Mechanisms in Pancreas Cancer. Cancers 13 (17) (2021)
Sandra Wiedenmann, Markus Breunig, Jessica Merkle, Christine von Toerne, Tihomir Georgiev, Michel Moussus, Lucas Schulte, Thomas Seufferlein, Michael Sterr, Heiko Lickert, Stephanie Ellen Weissinger, Peter Möller, Stefanie M Hauck, Meike Hohwieler, Alexander Kleger, Matthias Meier
Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip. Nature biomedical engineering 5 (8) (2021)
Janis A Müller, Ruediger Gross, Carina Conzelmann, Jana Krüger, Uta Merle, Johannes Steinhart, Tatjana Weil, Lennart Koepke, Caterina Prelli Bozzo, Clarissa Read, Giorgio Fois, Tim Eiseler, Julia Gehrmann, Joanne van Vuuren, Isabel Madeleine Klein, Manfred Frick, Ivan G Costa, Markus Breunig, Beate Grüner, Lynn Peters, Michael K Schuster, Stefan Liebau, Thomas Seufferlein, Steffen Stenger, Albrecht Stenzinger, Patrick E MacDonald, Frank Kirchhoff, Konstantin Maria Johannes Sparrer, Paul Walther, Heiko Lickert, Thomas F E Barth, Martin Wagner, Jan Münch, Sandra Heller, Alexander Kleger
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas. Nature metabolism 3 (2) (2021)
Frank Arnold, Pallavi U Mahaddalkar, Johann M Kraus, Xiaowei Zhong, Wendy Bergmann, Dharini Srinivasan, Johann Gout, Elodie Roger, Alica K Beutel, Eugen Zizer, Umesh Tharehalli, Nora Daiss, Ronan Russell, Lukas Perkhofer, Rupert Oellinger, Qiong Lin, Ninel Azoitei, Frank-Ulrich Weiss, Markus M Lerch, Stefan Liebau, Sarah-Fee Katz, André Lechel, Roland Rad, Thomas Seufferlein, Hans A Kestler, Michael Ott, Amar Deep Sharma, Patrick C Hermann, Alexander Kleger
Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (14) (2021)
Frank Arnold, Johann Gout, Heike Wiese, Stephanie E Weissinger, Elodie Roger, Lukas Perkhofer, Karolin Walter, Jeanette Scheible, Caterina Prelli Bozzo, André Lechel, Thomas Jens Ettrich, Ninel Azoitei, Li Hao, Axel Fürstberger, Ewa K Kaminska, Konstantin Maria Johannes Sparrer, Volker Rasche, Sebastian Wiese, Hans Armin Kestler, Peter Möller, Thomas Seufferlein, Pierre-Olivier Frappart, Alexander Kleger
RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer. Cancer research 81 (7) (2021)
Johann Gout, Lukas Perkhofer, Mareen Morawe, Frank Arnold, Michaela Ihle, Stephanie Biber, Sebastian Lange, Elodie Roger, Johann M Kraus, Katja Stifter, Stephan A Hahn, Andrea Zamperone, Thomas Engleitner, Martin Müller, Karolin Walter, Eva Rodriguez-Aznar, Bruno Sainz, Patrick C Hermann, Elisabeth Hessmann, Sebastian Müller, Ninel Azoitei, André Lechel, Stefan Liebau, Martin Wagner, Diane M Simeone, Hans A Kestler, Thomas Seufferlein, Lisa Wiesmüller, Roland Rad, Pierre-Olivier Frappart, Alexander Kleger
Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer. Gut 70 (4) (2020)
Lukas Perkhofer, Johann Gout, Elodie Roger, Fernando Kude de Almeida, Carolina Baptista Simões, Lisa Wiesmüller, Thomas Seufferlein, Alexander Kleger
DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives. Gut 70 (3) (2020)
Elodie Roger, Johann Gout, Frank Arnold, Alica K Beutel, Martin Müller, Alireza Abaei, Thomas F E Barth, Volker Rasche, Thomas Seufferlein, Lukas Perkhofer, Alexander Kleger
Maintenance Therapy for ATM-Deficient Pancreatic Cancer by Multiple DNA Damage Response Interferences after Platinum-Based Chemotherapy. Cells 9 (9) (2020)
Stefan Liebau, Holger A Russ, Alexander Kleger
Stem Cell Derived Organoids in Human Disease and Development. Stem cells international 2019 (2019)
Lukas Perkhofer, Melanie Engler, Johann Gout, Frank Arnold, Mareen Morawe, Markus Breunig, Thomas Seufferlein, Alexander Kleger, Pierre-Olivier Frappart
Pancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks. Stem cells international 2019 (2019)

Alexander Kleger.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Alexander Kleger