Bernhard Lüscher

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 33

Top Venues

Scientific reports

Cellular and molecular life sciences : CMLS

Journal of medicinal chemistry

Nature communications

RWTH Aachen University

University of Lausanne (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

RWTH Aachen University

Germany

Professor and Director :: Biochemistry and Molecular Biology

RWTH Aachen University

Germany

Professor :: Biochemistry and Molecular Biology

MHH

Germany

Assistent / Associate Professor :: Molecular Biology

FHCRC

United States

Staff Scientist

FHCRC

United States

Postdoc :: Basic Research

Education History

University of Lausanne

Switzerland

PHD :: Biochemistry

Publications

Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. Journal of medicinal chemistry 66 (2) (2023)
Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. Journal of medicinal chemistry 66 (2) (2023)
Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. Journal of medicinal chemistry 66 (2) (2023)
Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. Journal of medicinal chemistry 66 (2) (2023)
Mirna Barsoum, Roksaneh Sayadi Boroujeni, Alexander T Stenzel, Philip Bussmann, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L. Scientific reports 13 (1) (2023)
Mirna Barsoum, Roksaneh Sayadi Boroujeni, Alexander T Stenzel, Philip Bussmann, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L. Scientific reports 13 (1) (2023)
Mirna Barsoum, Roksaneh Sayadi Boroujeni, Alexander T Stenzel, Philip Bussmann, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L. Scientific reports 13 (1) (2023)
Mirna Barsoum, Roksaneh Sayadi Boroujeni, Alexander T Stenzel, Philip Bussmann, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L. Scientific reports 13 (1) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Mirna Barsoum, Roksaneh Sayadi Boroujeni, Alexander T Stenzel, Philip Bussmann, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L. Scientific reports 13 (1) (2023)
Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. Journal of medicinal chemistry (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. Journal of medicinal chemistry 66 (2) (2023)
Lisa Weixler, Nonso Josephat Ikenga, Jim Voorneveld, Gülcan Aydin, Timo Mhr Bolte, Jeffrey Momoh, Mareike Bütepage, Alexandra Golzmann, Bernhard Lüscher, Dmitri V Filippov, Roko Žaja, Karla L H Feijs
Protein and RNA ADP-ribosylation detection is influenced by sample preparation and reagents used. Life science alliance 6 (1) (2022)
Mirna Barsoum, Alexander T Stenzel, Agnieszka Bochyńska, Chao-Chung Kuo, Alexander Tsompanidis, Roksaneh Sayadi Boroujeni, Philip Bussmann, Juliane Lüscher-Firzlaff, Ivan G Costa, Bernhard Lüscher
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters. Scientific reports 12 (1) (2022)
Agnieszka Bochyńska, Alexander T Stenzel, Roksaneh Sayadi Boroujeni, Chao-Chung Kuo, Mirna Barsoum, Weili Liang, Philip Bussmann, Ivan G Costa, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes. Nucleic acids research 50 (14) (2022)
Mirna Barsoum, Alexander T Stenzel, Agnieszka Bochyńska, Chao-Chung Kuo, Alexander Tsompanidis, Roksaneh Sayadi Boroujeni, Philip Bussmann, Juliane Lüscher-Firzlaff, Ivan G Costa, Bernhard Lüscher
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters. Scientific reports 12 (1) (2022)
Bernhard Lüscher, Maud Verheirstraeten, Sarah Krieg, Patricia Korn
Intracellular mono-ADP-ribosyltransferases at the host-virus interphase. Cellular and molecular life sciences : CMLS 79 (6) (2022)
Mirna Barsoum, Alexander T Stenzel, Agnieszka Bochyńska, Chao-Chung Kuo, Alexander Tsompanidis, Roksaneh Sayadi Boroujeni, Philip Bussmann, Juliane Lüscher-Firzlaff, Ivan G Costa, Bernhard Lüscher
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters. Scientific reports 12 (1) (2022)
Mirna Barsoum, Alexander T Stenzel, Agnieszka Bochyńska, Chao-Chung Kuo, Alexander Tsompanidis, Roksaneh Sayadi Boroujeni, Philip Bussmann, Juliane Lüscher-Firzlaff, Ivan G Costa, Bernhard Lüscher
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters. Scientific reports 12 (1) (2022)
Mirna Barsoum, Alexander T Stenzel, Agnieszka Bochyńska, Chao-Chung Kuo, Alexander Tsompanidis, Roksaneh Sayadi Boroujeni, Philip Bussmann, Juliane Lüscher-Firzlaff, Ivan G Costa, Bernhard Lüscher
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters. Scientific reports 12 (1) (2022)
Patricia Korn, Arno Classen, Sudarshan Murthy, Riccardo Guareschi, Mirko M Maksimainen, Barbara E Lippok, Albert Galera-Prat, Sven T Sowa, Catharina Voigt, Sybille Krauß, Lari Lehtiö, Carsten Bolm, Bernhard Lüscher
Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10. ChemistryOpen 10 (10) (2021)
Bernhard Lüscher, Ivan Ahel, Matthias Altmeyer, Alan Ashworth, Peter Bai, Paul Chang, Michael Cohen, Daniela Corda, Françoise Dantzer, Matthew D Daugherty, Ted M Dawson, Valina L Dawson, Sebastian Deindl, Anthony R Fehr, Karla L H Feijs, Dmitri V Filippov, Jean-Philippe Gagné, Giovanna Grimaldi, Sebastian Guettler, Nicolas C Hoch, Michael O Hottiger, Patricia Korn, W Lee Kraus, Andreas Ladurner, Lari Lehtiö, Anthony K L Leung, Christopher J Lord, Aswin Mangerich, Ivan Matic, Jason Matthews, George-Lucian Moldovan, Joel Moss, Gioacchino Natoli, Michael L Nielsen, Mario Niepel, Friedrich Nolte, John Pascal, Bryce M Paschal, Krzysztof Pawłowski, Guy G Poirier, Susan Smith, Gyula Timinszky, Zhao-Qi Wang, José Yélamos, Xiaochun Yu, Roko Zaja, Mathias Ziegler
ADP-ribosyltransferases, an update on function and nomenclature. The FEBS journal (2021)
Qianqian Zhao, Riccardo Capelli, Paolo Carloni, Bernhard Lüscher, Jinyu Li, Sybille Krauß
Enhanced Sampling Approach to the Induced-Fit Docking Problem in Protein-Ligand Binding: The Case of Mono-ADP-Ribosylation Hydrolase Inhibitors. Journal of chemical theory and computation (2021)
Jörg Vervoorts, Dietbert Neumann, Bernhard Lüscher
The CCNY (cyclin Y)-CDK16 kinase complex: a new regulator of autophagy downstream of AMPK. Autophagy 16 (9) (2020)
Kathrin Nowak, Florian Rosenthal, Tobias Karlberg, Mareike Bütepage, Ann-Gerd Thorsell, Birgit Dreier, Jonas Grossmann, Jens Sobek, Ralph Imhof, Bernhard Lüscher, Herwig Schüler, Andreas Plückthun, Deena M Leslie Pedrioli, Michael O Hottiger
Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins. Nature communications 11 (1) (2020)
Marc Dohmen, Sarah Krieg, Georgios Agalaridis, Xiaoqing Zhu, Saifeldin N Shehata, Elisabeth Pfeiffenberger, Jan Amelang, Mareike Bütepage, Elena Buerova, Carolina M Pfaff, Dipanjan Chanda, Stephan Geley, Christian Preisinger, Kei Sakamoto, Bernhard Lüscher, Dietbert Neumann, Jörg Vervoorts
AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy. Nature communications 11 (1) (2020)
Juliane Lüscher-Firzlaff, Nicolas Chatain, Chao-Chung Kuo, Till Braunschweig, Agnieszka Bochyńska, Andrea Ullius, Bernd Denecke, Ivan G Costa, Steffen Koschmieder, Bernhard Lüscher
Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l. Scientific reports 9 (1) (2019)
Agnieszka Bochyńska, Juliane Lüscher-Firzlaff, Bernhard Lüscher
Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin. Cells 7 (3) (2018)
Bernhard Lüscher, Mareike Bütepage, Laura Eckei, Sarah Krieg, Patricia Verheugd, Brian H Shilton
ADP-Ribosylation, a Multifaceted Posttranslational Modification Involved in the Control of Cell Physiology in Health and Disease. Chemical reviews 118 (3) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Bernhard Lüscher