Christopher N Johnson

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 21

Top Venues

Journal of medicinal chemistry

Chemical reviews

RSC medicinal chemistry

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

James E H Day, Valerio Berdini, Joan Castro, Gianni Chessari, Thomas G Davies, Philip J Day, Jeffrey D St Denis, Hideto Fujiwara, Satoshi Fukaya, Christopher C F Hamlett, Keisha Hearn, Steven D Hiscock, Rhian S Holvey, Satoru Ito, Navrohit Kandola, Yasuo Kodama, John W Liebeschuetz, Vanessa Martins, Kenichi Matsuo, Paul N Mortenson, Sandra Muench, Yoko Nakatsuru, Hiroaki Ochiiwa, Nicholas Palmer, Torren Peakman, Amanda Price, Michael Reader, David C Rees, Sharna J Rich, Alpesh Shah, Yoshihiro Shibata, Tomoko Smyth, David G Twigg, Nicola G Wallis, Glyn Williams, Nicola E Wilsher, Andrew Woodhead, Tadashi Shimamura, Christopher N Johnson
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). Journal of medicinal chemistry 67 (6) (2024)
James E H Day, Valerio Berdini, Joan Castro, Gianni Chessari, Thomas G Davies, Philip J Day, Jeffrey D St Denis, Hideto Fujiwara, Satoshi Fukaya, Christopher C F Hamlett, Keisha Hearn, Steven D Hiscock, Rhian S Holvey, Satoru Ito, Navrohit Kandola, Yasuo Kodama, John W Liebeschuetz, Vanessa Martins, Kenichi Matsuo, Paul N Mortenson, Sandra Muench, Yoko Nakatsuru, Hiroaki Ochiiwa, Nicholas Palmer, Torren Peakman, Amanda Price, Michael Reader, David C Rees, Sharna J Rich, Alpesh Shah, Yoshihiro Shibata, Tomoko Smyth, David G Twigg, Nicola G Wallis, Glyn Williams, Nicola E Wilsher, Andrew Woodhead, Tadashi Shimamura, Christopher N Johnson
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). Journal of medicinal chemistry (2024)
Nick Palmer, Christopher Agnew, Caroline Benn, William J Buffham, Joan N Castro, Gianni Chessari, Mellissa Clark, Benjamin D Cons, Joseph E Coyle, Lee A Dawson, Christopher C F Hamlett, Charlotte Hodson, Finn Holding, Christopher N Johnson, John W Liebeschuetz, Pravin Mahajan, James M McCarthy, Christopher W Murray, Marc O'Reilly, Torren Peakman, Amanda Price, Magdalini Rapti, Judith Reeks, Patrick Schöpf, Jeffrey D St Denis, Chiara Valenzano, Nicola G Wallis, Reto Walser, Heather Weir, Nicola E Wilsher, Andrew Woodhead, Carla F Bento, Dominic Tisi
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase. Journal of medicinal chemistry 67 (13) (2024)
Nick Palmer, Christopher Agnew, Caroline Benn, William J Buffham, Joan N Castro, Gianni Chessari, Mellissa Clark, Benjamin D Cons, Joseph E Coyle, Lee A Dawson, Christopher C F Hamlett, Charlotte Hodson, Finn Holding, Christopher N Johnson, John W Liebeschuetz, Pravin Mahajan, James M McCarthy, Christopher W Murray, Marc O'Reilly, Torren Peakman, Amanda Price, Magdalini Rapti, Judith Reeks, Patrick Schöpf, Jeffrey D St Denis, Chiara Valenzano, Nicola G Wallis, Reto Walser, Heather Weir, Nicola E Wilsher, Andrew Woodhead, Carla F Bento, Dominic Tisi
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase. Journal of medicinal chemistry (2024)
Nick Palmer, Christopher Agnew, Caroline Benn, William J Buffham, Joan N Castro, Gianni Chessari, Mellissa Clark, Benjamin D Cons, Joseph E Coyle, Lee A Dawson, Christopher C F Hamlett, Charlotte Hodson, Finn Holding, Christopher N Johnson, John W Liebeschuetz, Pravin Mahajan, James M McCarthy, Christopher W Murray, Marc O'Reilly, Torren Peakman, Amanda Price, Magdalini Rapti, Judith Reeks, Patrick Schöpf, Jeffrey D St Denis, Chiara Valenzano, Nicola G Wallis, Reto Walser, Heather Weir, Nicola E Wilsher, Andrew Woodhead, Carla F Bento, Dominic Tisi
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase. Journal of medicinal chemistry 67 (13) (2024)
James E H Day, Valerio Berdini, Joan Castro, Gianni Chessari, Thomas G Davies, Philip J Day, Jeffrey D St Denis, Hideto Fujiwara, Satoshi Fukaya, Christopher C F Hamlett, Keisha Hearn, Steven D Hiscock, Rhian S Holvey, Satoru Ito, Navrohit Kandola, Yasuo Kodama, John W Liebeschuetz, Vanessa Martins, Kenichi Matsuo, Paul N Mortenson, Sandra Muench, Yoko Nakatsuru, Hiroaki Ochiiwa, Nicholas Palmer, Torren Peakman, Amanda Price, Michael Reader, David C Rees, Sharna J Rich, Alpesh Shah, Yoshihiro Shibata, Tomoko Smyth, David G Twigg, Nicola G Wallis, Glyn Williams, Nicola E Wilsher, Andrew Woodhead, Tadashi Shimamura, Christopher N Johnson
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). Journal of medicinal chemistry 67 (6) (2024)
Connor J Taylor, Alexander Pomberger, Kobi C Felton, Rachel Grainger, Magda H Barecka, Thomas W Chamberlain, Richard A Bourne, Christopher N Johnson, Alexei A Lapkin
A Brief Introduction to Chemical Reaction Optimization. Chemical reviews 123 (6) (2023)
Chloe Townley, Davide Branduardi, Gianni Chessari, Benjamin D Cons, Charlotte Griffiths-Jones, Richard J Hall, Christopher N Johnson, Yuji Ochi, Stuart Whibley, Rachel Grainger
Enabling synthesis in fragment-based drug discovery (FBDD): microscale high-throughput optimisation of the medicinal chemist's toolbox reactions. RSC medicinal chemistry 14 (12) (2023)
Connor J Taylor, Alexander Pomberger, Kobi C Felton, Rachel Grainger, Magda H Barecka, Thomas W Chamberlain, Richard A Bourne, Christopher N Johnson, Alexei A Lapkin
A Brief Introduction to Chemical Reaction Optimization. Chemical reviews (2023)
Connor J Taylor, Alexander Pomberger, Kobi C Felton, Rachel Grainger, Magda H Barecka, Thomas W Chamberlain, Richard A Bourne, Christopher N Johnson, Alexei A Lapkin
A Brief Introduction to Chemical Reaction Optimization. Chemical reviews (2023)
Chloe Townley, Davide Branduardi, Gianni Chessari, Benjamin D Cons, Charlotte Griffiths-Jones, Richard J Hall, Christopher N Johnson, Yuji Ochi, Stuart Whibley, Rachel Grainger
Enabling synthesis in fragment-based drug discovery (FBDD): microscale high-throughput optimisation of the medicinal chemist's toolbox reactions. RSC medicinal chemistry 14 (12) (2023)
Connor J Taylor, Alexander Pomberger, Kobi C Felton, Rachel Grainger, Magda H Barecka, Thomas W Chamberlain, Richard A Bourne, Christopher N Johnson, Alexei A Lapkin
A Brief Introduction to Chemical Reaction Optimization. Chemical reviews 123 (6) (2023)
Connor J Taylor, Kobi C Felton, Daniel S Wigh, Mohammed I Jeraal, Rachel Grainger, Gianni Chessari, Christopher N Johnson, Alexei A Lapkin
Accelerated Chemical Reaction Optimization Using Multi-Task Learning. ACS central science 9 (5) (2023)
Iwan J P de Esch, Daniel A Erlanson, Wolfgang Jahnke, Christopher N Johnson, Louise Walsh
Fragment-to-Lead Medicinal Chemistry Publications in 2020. Journal of medicinal chemistry 65 (1) (2021)
Gianni Chessari, Ian R Hardcastle, Jong Sook Ahn, Burcu Anil, Elizabeth Anscombe, Ruth H Bawn, Luke D Bevan, Timothy J Blackburn, Ildiko Buck, Celine Cano, Benoit Carbain, Juan Castro, Ben Cons, Sarah J Cully, Jane A Endicott, Lynsey Fazal, Bernard T Golding, Roger J Griffin, Karen Haggerty, Suzannah J Harnor, Keisha Hearn, Stephen Hobson, Rhian S Holvey, Steven Howard, Claire E Jennings, Christopher N Johnson, John Lunec, Duncan C Miller, David R Newell, Martin E M Noble, Judith Reeks, Charlotte H Revill, Christiane Riedinger, Jeffrey D St Denis, Emiliano Tamanini, Huw Thomas, Neil T Thompson, Mladen Vinković, Stephen R Wedge, Pamela A Williams, Nicola E Wilsher, Bian Zhang, Yan Zhao
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction. Journal of medicinal chemistry 64 (7) (2021)
Daniel A Erlanson, Iwan J P de Esch, Wolfgang Jahnke, Christopher N Johnson, Paul N Mortenson
Fragment-to-Lead Medicinal Chemistry Publications in 2018. Journal of medicinal chemistry 63 (9) (2020)
Wolfgang Jahnke, Daniel A Erlanson, Iwan J P de Esch, Christopher N Johnson, Paul N Mortenson, Yuji Ochi, Tatsuya Urushima
Fragment-to-Lead Medicinal Chemistry Publications in 2019. Journal of medicinal chemistry 63 (24) (2020)
Christopher N Johnson, Jong Sook Ahn, Ildiko M Buck, Elisabetta Chiarparin, James E H Day, Anna Hopkins, Steven Howard, Edward J Lewis, Vanessa Martins, Alessia Millemaggi, Joanne M Munck, Lee W Page, Torren Peakman, Michael Reader, Sharna J Rich, Gordon Saxty, Tomoko Smyth, Neil T Thompson, George A Ward, Pamela A Williams, Nicola E Wilsher, Gianni Chessari
A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660). Journal of medicinal chemistry 61 (16) (2018)
Paul N Mortenson, Daniel A Erlanson, Iwan J P de Esch, Wolfgang Jahnke, Christopher N Johnson
Fragment-to-Lead Medicinal Chemistry Publications in 2017. Journal of medicinal chemistry 62 (8) (2018)
Rachel Grainger, Tom D Heightman, Steven V Ley, Fabio Lima, Christopher N Johnson
Enabling synthesis in fragment-based drug discovery by reactivity mapping: photoredox-mediated cross-dehydrogenative heteroarylation of cyclic amines. Chemical science 10 (8) (2018)
Christopher N Johnson, Daniel A Erlanson, Wolfgang Jahnke, Paul N Mortenson, David C Rees
Fragment-to-Lead Medicinal Chemistry Publications in 2016. Journal of medicinal chemistry 61 (5) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christopher N Johnson