David A Largaespada

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 19

Top Topics

Acute Myeloid Leukemia

Peripheral Nerve

Top Venues

Nature communications

bioRxiv : the preprint server for biology

International journal of molecular sciences

Molecular cancer research : MCR

This page only lists publications with an associated author ORCID identifier.

Publications

Kyle B Williams, Alex T Larsson, Bryant J Keller, Katherine E Chaney, Rory L Williams, Minu M Bhunia, Garrett M Draper, Tyler A Jubenville, Sue K Rathe, Christopher L Moertel, Nancy Ratner, David A Largaespada
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors. bioRxiv : the preprint server for biology (2024)
Kyle B Williams, Alex T Larsson, Bryant J Keller, Katherine E Chaney, Rory L Williams, Minu M Bhunia, Garrett M Draper, Tyler A Jubenville, Sue K Rathe, Christopher L Moertel, Nancy Ratner, David A Largaespada
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors. bioRxiv : the preprint server for biology (2024)
Kyle B Williams, Alex T Larsson, Bryant J Keller, Katherine E Chaney, Rory L Williams, Minu M Bhunia, Garrett M Draper, Tyler A Jubenville, Sue K Rathe, Christopher L Moertel, Nancy Ratner, David A Largaespada
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors. bioRxiv : the preprint server for biology (2024)
Kyle B Williams, Alex T Larsson, Bryant J Keller, Katherine E Chaney, Rory L Williams, Minu M Bhunia, Garrett M Draper, Tyler A Jubenville, Sue K Rathe, Christopher L Moertel, Nancy Ratner, David A Largaespada
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors. bioRxiv : the preprint server for biology (2024)
Matthew R Pawlak, Adam T Smiley, Maria Paz Ramirez, Marcus D Kelly, Ghaidan A Shamsan, Sarah M Anderson, Branden A Smeester, David A Largaespada, David J Odde, Wendy Ryan Gordon
RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes. Nature communications 14 (1) (2023)
Suganth Suppiah, Sheila Mansouri, Yasin Mamatjan, Jeffrey C Liu, Minu M Bhunia, Vikas Patil, Prisni Rath, Bharati Mehani, Pardeep Heir, Severa Bunda, German L Velez-Reyes, Olivia Singh, Nazanin Ijad, Neda Pirouzmand, Tatyana Dalcourt, Ying Meng, Shirin Karimi, Qingxia Wei, Farshad Nassiri, Trevor J Pugh, Gary D Baider, Kenneth D Aldape, David A Largaespada, Gelareh Zadeh
Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Suganth Suppiah, Sheila Mansouri, Yasin Mamatjan, Jeffrey C Liu, Minu M Bhunia, Vikas Patil, Prisni Rath, Bharati Mehani, Pardeep Heir, Severa Bunda, German L Velez-Reyes, Olivia Singh, Nazanin Ijad, Neda Pirouzmand, Tatyana Dalcourt, Ying Meng, Shirin Karimi, Qingxia Wei, Farshad Nassiri, Trevor J Pugh, Gary D Baider, Kenneth D Aldape, David A Largaespada, Gelareh Zadeh
Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Matthew R Pawlak, Adam T Smiley, Maria Paz Ramirez, Marcus D Kelly, Ghaidan A Shamsan, Sarah M Anderson, Branden A Smeester, David A Largaespada, David J Odde, Wendy Ryan Gordon
RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes. Nature communications 14 (1) (2023)
Matthew R Pawlak, Adam T Smiley, Maria Paz Ramirez, Marcus D Kelly, Ghaidan A Shamsan, Sarah M Anderson, Branden A Smeester, David A Largaespada, David J Odde, Wendy Ryan Gordon
RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes. Nature communications 14 (1) (2023)
Matthew R Pawlak, Adam T Smiley, Maria Paz Ramirez, Marcus D Kelly, Ghaidan A Shamsan, Sarah M Anderson, Branden A Smeester, David A Largaespada, David J Odde, Wendy Ryan Gordon
RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes. Nature communications 14 (1) (2023)
Jiawan Wang, Ana Calizo, Lindy Zhang, James C Pino, Yang Lyu, Kai Pollard, Xiaochun Zhang, Alex T Larsson, Eric Conniff, Nicolas J Llosa, David K Wood, David A Largaespada, Susan E Moody, Sara J C Gosline, Angela C Hirbe, Christine A Pratilas
CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors. Science advances 9 (47) (2023)
Suganth Suppiah, Sheila Mansouri, Yasin Mamatjan, Jeffrey C Liu, Minu M Bhunia, Vikas Patil, Prisni Rath, Bharati Mehani, Pardeep Heir, Severa Bunda, German L Velez-Reyes, Olivia Singh, Nazanin Ijad, Neda Pirouzmand, Tatyana Dalcourt, Ying Meng, Shirin Karimi, Qingxia Wei, Farshad Nassiri, Trevor J Pugh, Gary D Baider, Kenneth D Aldape, David A Largaespada, Gelareh Zadeh
Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Keisuke Sugita, Iichiroh Onishi, Ran Nakayama, Sachiko Ishibashi, Masumi Ikeda, Miori Inoue, Rina Narita, Shiori Oshima, Kaho Shimizu, Shinichiro Saito, Shingo Sato, Branden S Moriarity, Kouhei Yamamoto, David A Largaespada, Masanobu Kitagawa, Morito Kurata
Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell-cell interactions. Communications biology 6 (1) (2023)
Jordan A Naumann, Prokopios P Argyris, Michael A Carpenter, Harshita B Gupta, Yanjun Chen, Nuri A Temiz, Yufan Zhou, Cameron Durfee, Joshua Proehl, Brenda L Koniar, Silvestro Giovanni Conticello, David A Largaespada, William L Brown, Hideki Aihara, Rachel Isaksson Vogel, Reuben S Harris
DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo. International journal of molecular sciences 24 (11) (2023)
Morito Kurata, Marie Lue Antony, Klara E Noble-Orcutt, Susan K Rathe, Yoonkyu Lee, Hidehiro Furuno, Sachiko Ishibashi, Masumi Ikeda, Kouhei Yamamoto, Masanobu Kitagawa, David A Largaespada, Zohar Sachs
Proliferation and Self-Renewal Are Differentially Sensitive to NRASG12V Oncogene Levels in an Acute Myeloid Leukemia Cell Line. Molecular cancer research : MCR 20 (11) (2022)
Akiya Tatsumi, Haruka Hirakochi, Satomi Inoue, Yosuke Tanaka, Hidehiro Furuno, Masumi Ikeda, Sachiko Ishibashi, Towako Taguchi, Kouhei Yamamoto, Iichiroh Ohnishi, Zohar Sachs, David A Largaespada, Masanobu Kitagawa, Morito Kurata
Identification of NRAS Downstream Genes with CRISPR Activation Screening. Biology 11 (11) (2022)
Sara H Osum, Adrienne L Watson, David A Largaespada
Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1. International journal of molecular sciences 22 (4) (2021)
Germán L Vélez-Reyes, Nicholas Koes, Ji Hae Ryu, Gabriel Kaufmann, Mariah Berner, Madison T Weg, Natalie K Wolf, Susan K Rathe, Nancy Ratner, Branden S Moriarity, David A Largaespada
Transposon Mutagenesis-Guided CRISPR/Cas9 Screening Strongly Implicates Dysregulation of Hippo/YAP Signaling in Malignant Peripheral Nerve Sheath Tumor Development. Cancers 13 (7) (2021)
Ibrahim Y Abdelgawad, Marianne K O Grant, Flavia E Popescu, David A Largaespada, Beshay N Zordoky
Doxorubicin Paradoxically Ameliorates Tumor-Induced Inflammation in Young Mice. International journal of molecular sciences 22 (16) (2021)