David E Heinrichs

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 27

Top Venues

Infection and immunity

Proceedings of the National Academy of Sciences of the United States of America

mBio

Journal of bacteriology

University of Western Ontario

Queens' University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Western Ontario Oct 15 1998

Canada

Professor :: Microbiology & Immunology

Education History

Queens' University Sep 01 1989 - Aug 15 1995

Canada

PHD :: Microbiology & Immunology

Univeristy of Manitoba Sep 01 1985 - Apr 30 1989

Canada

BSC :: Microbiology

Publications

Allison C Leonard, Mariya I Goncheva, Stephanie E Gilbert, Hiba Shareefdeen, Laurenne E Petrie, Laura K Thompson, Cezar M Khursigara, David E Heinrichs, Georgina Cox
Autolysin-mediated peptidoglycan hydrolysis is required for the surface display of Staphylococcus aureus cell wall-anchored proteins. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Thiago Fauerharmel-Nunes, Ronald S Flannagan, Mariya I Goncheva, Arnold S Bayer, Vance G Fowler, Liana C Chan, Michael R Yeaman, Yan Q Xiong, David E Heinrichs
MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure. Infection and immunity 91 (1) (2023)
Allison C Leonard, Mariya I Goncheva, Stephanie E Gilbert, Hiba Shareefdeen, Laurenne E Petrie, Laura K Thompson, Cezar M Khursigara, David E Heinrichs, Georgina Cox
Autolysin-mediated peptidoglycan hydrolysis is required for the surface display of Staphylococcus aureus cell wall-anchored proteins. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Allison C Leonard, Mariya I Goncheva, Stephanie E Gilbert, Hiba Shareefdeen, Laurenne E Petrie, Laura K Thompson, Cezar M Khursigara, David E Heinrichs, Georgina Cox
Autolysin-mediated peptidoglycan hydrolysis is required for the surface display of Staphylococcus aureus cell wall-anchored proteins. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Thiago Fauerharmel-Nunes, Ronald S Flannagan, Mariya I Goncheva, Arnold S Bayer, Vance G Fowler, Liana C Chan, Michael R Yeaman, Yan Q Xiong, David E Heinrichs
MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure. Infection and immunity (2023)
Thiago Fauerharmel-Nunes, Ronald S Flannagan, Mariya I Goncheva, Arnold S Bayer, Vance G Fowler, Liana C Chan, Michael R Yeaman, Yan Q Xiong, David E Heinrichs
MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure. Infection and immunity 91 (1) (2023)
Thiago Fauerharmel-Nunes, Ronald S Flannagan, Mariya I Goncheva, Arnold S Bayer, Vance G Fowler, Liana C Chan, Michael R Yeaman, Yan Q Xiong, David E Heinrichs
MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure. Infection and immunity 91 (1) (2023)
Thiago Fauerharmel-Nunes, Ronald S Flannagan, Mariya I Goncheva, Arnold S Bayer, Vance G Fowler, Liana C Chan, Michael R Yeaman, Yan Q Xiong, David E Heinrichs
MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure. Infection and immunity 91 (1) (2023)
Denny Chin, Ronald S Flannagan, Stephen W Tuffs, Jeremy K Chan, John K McCormick, David E Heinrichs
Staphylococcus lugdunensis Uses the Agr Regulatory System to Resist Killing by Host Innate Immune Effectors. Infection and immunity 90 (10) (2022)
Stephen W Tuffs, Mariya I Goncheva, Stacey X Xu, Heather C Craig, Katherine J Kasper, Joshua Choi, Ronald S Flannagan, Steven M Kerfoot, David E Heinrichs, John K McCormick
Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production. Proceedings of the National Academy of Sciences of the United States of America 119 (8) (2022)
Izabela Z Batko, Ronald S Flannagan, Veronica Guariglia-Oropeza, Jessica R Sheldon, David E Heinrichs
Heme-Dependent Siderophore Utilization Promotes Iron-Restricted Growth of the Staphylococcus aureus hemB Small-Colony Variant. Journal of bacteriology 203 (24) (2021)
Denny Chin, Mariya I Goncheva, Ronald S Flannagan, Shayna R Deecker, Veronica Guariglia-Oropeza, Alexander W Ensminger, David E Heinrichs
Coagulase-negative staphylococci release a purine analog that inhibits Staphylococcus aureus virulence. Nature communications 12 (1) (2021)
David W Watson, Santiago L Iglesias, Edward M Vasarhelyi, David E Heinrichs
GraXRS-Dependent Resistance of Staphylococcus aureus to Human Osteoarthritic Synovial Fluid. mSphere 6 (2) (2021)
Ronald S Flannagan, David E Heinrichs
Macrophage-driven nutrient delivery to phagosomal Staphylococcus aureus supports bacterial growth. EMBO reports 21 (8) (2020)
Angelika Jochim, Lea Adolf, Darya Belikova, Nadine Anna Schilling, Inda Setyawati, Denny Chin, Severien Meyers, Peter Verhamme, David E Heinrichs, Dirk Jan Slotboom, Simon Heilbronner
An ECF-type transporter scavenges heme to overcome iron-limitation in Staphylococcus lugdunensis. eLife 9 (2020)
Mariya I Goncheva, Ronald S Flannagan, David E Heinrichs
De Novo Purine Biosynthesis Is Required for Intracellular Growth of Staphylococcus aureus and for the Hypervirulence Phenotype of a purR Mutant. Infection and immunity 88 (5) (2020)
Manouk Vrieling, Stephen W Tuffs, Gonzalo Yebra, Marleen Y van Smoorenburg, Joana Alves, Amy C Pickering, Joo Youn Park, Nogi Park, David E Heinrichs, Lindert Benedictus, Timothy Connelley, Keun-Seok Seo, John K McCormick, J Ross Fitzgerald
Population Analysis of Staphylococcus aureus Reveals a Cryptic, Highly Prevalent Superantigen SElW That Contributes to the Pathogenesis of Bacteremia. mBio 11 (5) (2020)
Meghan M Verstraete, L Daniela Morales, Marek J Kobylarz, Slade A Loutet, Holly A Laakso, Tyler B Pinter, Martin J Stillman, David E Heinrichs, Michael E P Murphy
The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus. The Journal of biological chemistry 294 (30) (2019)
William J Perry, Jeffrey M Spraggins, Jessica R Sheldon, Caroline M Grunenwald, David E Heinrichs, James E Cassat, Eric P Skaar, Richard M Caprioli
Staphylococcus aureus exhibits heterogeneous siderophore production within the vertebrate host. Proceedings of the National Academy of Sciences of the United States of America 116 (44) (2019)
Omar M El-Halfawy, Tomasz L Czarny, Ronald S Flannagan, Jonathan Day, José Carlos Bozelli, Robert C Kuiack, Ahmed Salim, Philip Eckert, Richard M Epand, Martin J McGavin, Michael G Organ, David E Heinrichs, Eric D Brown
Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA. Nature chemical biology 16 (2) (2019)
Heba Alnaseri, Robert C Kuiack, Katherine A Ferguson, James E T Schneider, David E Heinrichs, Martin J McGavin
DNA Binding and Sensor Specificity of FarR, a Novel TetR Family Regulator Required for Induction of the Fatty Acid Efflux Pump FarE in Staphylococcus aureus. Journal of bacteriology 201 (3) (2019)
Liwen Deng, Katrin Schilcher, Lindsey R Burcham, Jakub M Kwiecinski, Paige M Johnson, Steven R Head, David E Heinrichs, Alexander R Horswill, Kelly S Doran
Identification of Key Determinants of Staphylococcus aureus Vaginal Colonization. mBio 10 (6) (2019)
Mariya I Goncheva, Ronald S Flannagan, Brigid E Sterling, Holly A Laakso, Nancy C Friedrich, Julienne C Kaiser, David W Watson, Christy H Wilson, Jessica R Sheldon, Martin J McGavin, Patti K Kiser, David E Heinrichs
Stress-induced inactivation of the Staphylococcus aureus purine biosynthesis repressor leads to hypervirulence. Nature communications 10 (1) (2019)
Ronald S Flannagan, David W Watson, Bas G J Surewaard, Paul Kubes, David E Heinrichs
The surreptitious survival of the emerging pathogen Staphylococcus lugdunensis within macrophages as an immune evasion strategy. Cellular microbiology 20 (11) (2018)
Julienne C Kaiser, Alyssa N King, Jason C Grigg, Jessica R Sheldon, David R Edgell, Michael E P Murphy, Shaun R Brinsmade, David E Heinrichs
Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide. PLoS genetics 14 (1) (2018)
Ronald S Flannagan, Robert C Kuiack, Martin J McGavin, David E Heinrichs
Staphylococcus aureus Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages. mBio 9 (4) (2018)
Julienne C Kaiser, David E Heinrichs
Branching Out: Alterations in Bacterial Physiology and Virulence Due to Branched-Chain Amino Acid Deprivation. mBio 9 (5) (2018)

David E Heinrichs.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

David E Heinrichs