Dimitri Krainc

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Topics

Genome Wide Association

Endoplasmic Reticulum

Top Venues

The Journal of cell biology

Science translational medicine

Nature reviews. Neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Leonie F Schröder, Wesley Peng, Ge Gao, Yvette C Wong, Michael Schwake, Dimitri Krainc
VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons. The Journal of cell biology 223 (5) (2024)
Robert Coukos, Dimitri Krainc
Key genes and convergent pathogenic mechanisms in Parkinson disease. Nature reviews. Neuroscience (2024)
Leonie F Schröder, Wesley Peng, Ge Gao, Yvette C Wong, Michael Schwake, Dimitri Krainc
VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons. The Journal of cell biology 223 (5) (2024)
Robert Coukos, Dimitri Krainc
Key genes and convergent pathogenic mechanisms in Parkinson disease. Nature reviews. Neuroscience 25 (6) (2024)
Cloé Domenighetti, Pierre-Emmanuel Sugier, Ashwin Ashok Kumar Sreelatha, Claudia Schulte, Sandeep Grover, Berta Portugal, Pei-Chen Lee, Patrick May, Dheeraj Bobbili, Milena Radivojkov Blagojevic, Peter Lichtner, Andrew B Singleton, Dena Hernandez, Connor Edsall, George D Mellick, Alexander A Zimprich, Walter Pirker, Ekaterina A Rogaeva, Anthony E Lang, Sulev Kõks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugenie Mutez, Kathrin Brockman, Angela B Deutschländer, Georgios M Hadjigeorgiou, Efthimios Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna L Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Hirotaka Matsuo, Akiyoshi Nakayama, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yoon Joong Kim, Pierre Kolber, Bart P C Van De Warrenburg, Bastiaan R Bloem, Mathias Toft, Lasse Pihlstrom, Leonor Correia Guedes, Joaquim José Ferreira, Soraya Bardien, Jonathan A Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Mónica Diez-Fairen, Karin Wirdefeldt, Nancy L Pedersen, Caroline Ran, Andrea Carmine Belin, Andreas Puschmann, Clara Hellberg, Carl E Clarke, Karen E Morrison, Manuela M X Tan, Dimitri Krainc, Lena F Burbulla, Matthew J Farrer, Rejko Krüger, Thomas Gasser, Manu Sharma, Alexis Elbaz, null null
Association of Body Mass Index and Parkinson Disease: A Bidirectional Mendelian Randomization Study. Neurology 103 (3) (2024)
Leonie F Schröder, Wesley Peng, Ge Gao, Yvette C Wong, Michael Schwake, Dimitri Krainc
VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons. The Journal of cell biology 223 (5) (2024)
Leonie F Schröder, Wesley Peng, Ge Gao, Yvette C Wong, Michael Schwake, Dimitri Krainc
VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons. The Journal of cell biology 223 (5) (2024)
Robert Coukos, Dimitri Krainc
Key genes and convergent pathogenic mechanisms in Parkinson disease. Nature reviews. Neuroscience 25 (6) (2024)
Dimitri Krainc, William J Martin, Kimberley J Billingsley, Frances E Jensen, Sarah A Tishkoff, William Z Potter, Steven E Hyman
Shifting the trajectory of therapeutic development for neurological and psychiatric disorders. Science translational medicine 15 (720) (2023)
Dimitri Krainc, William J Martin, Kimberley J Billingsley, Frances E Jensen, Sarah A Tishkoff, William Z Potter, Steven E Hyman
Shifting the trajectory of therapeutic development for neurological and psychiatric disorders. Science translational medicine 15 (720) (2023)
Alessia Nasca, Niccolò E Mencacci, Federica Invernizzi, Michael Zech, Ignacio J Keller Sarmiento, Andrea Legati, Chiara Frascarelli, Bernabe Ignacio Bustos, Luigi Michele Romito, Dimitri Krainc, Juliane Winkelmann, Miryam Carecchio, Nardo Nardocci, Giovanna Zorzi, Holger Prokisch, Steven J Lubbe, Barbara Garavaglia, Daniele Ghezzi
Variants in ATP5F1B are associated with dominantly inherited dystonia. Brain : a journal of neurology (2023)
Wesley Peng, Leonie F Schröder, Pingping Song, Yvette C Wong, Dimitri Krainc
Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson's disease. Science advances 9 (29) (2023)
Dimitri Krainc, William J Martin, Kimberley J Billingsley, Frances E Jensen, Sarah A Tishkoff, William Z Potter, Steven E Hyman
Shifting the trajectory of therapeutic development for neurological and psychiatric disorders. Science translational medicine 15 (720) (2023)
Yvette C Wong, Nirupa D Jayaraj, Tayler B Belton, George C Shum, Hannah E Ball, Dongjun Ren, Abigail L D Tadenev, Dimitri Krainc, Robert W Burgess, Daniela M Menichella
Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons. Proceedings of the National Academy of Sciences of the United States of America 120 (44) (2023)
Sandeep Grover, Ashwin Ashok Kumar Sreelatha, Lasse Pihlstrom, Cloé Domenighetti, Claudia Schulte, Pierre-Emmanuel Sugier, Milena Radivojkov-Blagojevic, Peter Lichtner, Océane Mohamed, Berta Portugal, Zied Landoulsi, Patrick May, Dheeraj Bobbili, Connor Edsall, Felix Bartusch, Maximilian Hanussek, Jens Krüger, Dena G Hernandez, Cornelis Blauwendraat, George D Mellick, Alexander Zimprich, Walter Pirker, Manuela Tan, Ekaterina Rogaeva, Anthony Lang, Sulev Kõks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugenie Mutez, Kathrin Brockmann, Angela B Deutschländer, Georges M Hadjigeorgiou, Efthimos Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Lena F Burbulla, Hirotaka Matsuo, Yusuke Kawamura, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yoon Joong Kim, Lukas Pavelka, Bart P C van de Warrenburg, Bastiaan R Bloem, Andrew B Singleton, Jan Aasly, Mathias Toft, Leonor Correia Guedes, Joaquim J Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Monica Diez-Fairen, Karin Wirdefeldt, Nancy L Pedersen, Caroline Ran, Andrea C Belin, Andreas Puschmann, Clara Hellberg, Carl E Clarke, Karen E Morrison, Dimitri Krainc, Matthew J Farrer, Rejko Krüger, Alexis Elbaz, Thomas Gasser, Manu Sharma, null null
Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease: Evidence From the COURAGE-PD Consortium. Neurology 99 (7) (2022)
Bernabe Ignacio Bustos, Kimberley Billingsley, Cornelis Blauwendraat, Raphael J Gibbs, Ziv Gan Or, Dimitri Krainc, Andrew B Singleton, Steven J Lubbe, null null
Genome-wide contribution of common short-tandem repeats to Parkinson's disease genetic risk. Brain : a journal of neurology (2022)
Yvette C Wong, Soojin Kim, Jasmine Cisneros, Catherine G Molakal, Pingping Song, Steven J Lubbe, Dimitri Krainc
Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics. The Journal of cell biology 221 (10) (2022)
Sandeep Grover, Ashok Kumar Sreelatha Ashwin, Lasse Pihlstrom, Cloé Domenighetti, Claudia Schulte, Pierre-Emmanuel Sugier, Milena Radivojkov-Blagojevic, Peter Lichtner, Océane Mohamed, Berta Portugal, Zied Landoulsi, Patrick May, Dheeraj Bobbili, Connor Edsall, Felix Bartusch, Maximilian Hanussek, Jens Krüger, Dena G Hernandez, Cornelis Blauwendraat, George D Mellick, Alexander Zimprich, Walter Pirker, Manuela Tan, Ekaterina Rogaeva, Anthony Lang, Sulev Kõks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugenie Mutez, Kathrin Brockmann, Angela B Deutschländer, Georges M Hadjigeorgiou, Efthimos Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Lena F Burbulla, Hirotaka Matsuo, Yusuke Kawamura, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yoon Joong Kim, Lukas Pavelka, Bart Pc van de Warrenburg, Bastiaan R Bloem, Andrew B Singleton, Jan Aasly, Mathias Toft, Leonor Correia Guedes, Joaquim J Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Monica Diez-Fairen, Karin Wirdefeldt, Nancy L Pedersen, Caroline Ran, Andrea C Belin, Andreas Puschmann, Clara Hellberg, Carl E Clarke, Karen E Morrison, Dimitri Krainc, Matthew J Farrer, Rejko Krüger, Alexis Elbaz, Thomas Gasser, Manu Sharma, null null
Genome-wide Association and Meta-analysis of Age-at-Onset in Parkinson Disease: Evidence From COURAGE-PD Consortium. Neurology (2022)
Soojin Kim, Yvette C Wong, Fanding Gao, Dimitri Krainc
Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease. Nature communications 12 (1) (2021)
Ibrahim Boussaad, Carolin D Obermaier, Zoé Hanss, Dheeraj R Bobbili, Silvia Bolognin, Enrico Glaab, Katarzyna Wołyńska, Nicole Weisschuh, Laura De Conti, Caroline May, Florian Giesert, Dajana Grossmann, Annika M Lambert, Susanne Kirchen, Maria Biryukov, Lena F Burbulla, François Massart, Jill Bohler, Gérald Cruciani, Benjamin Schmid, Annerose Kurz-Drexler, Patrick May, Stefano Duga, Christine Klein, Jens Christian Schwamborn, Katrin Marcus, Dirk Woitalla, Daniela Maria Vogt Weisenhorn, Wolfgang Wurst, Marco Baralle, Dimitri Krainc, Thomas Gasser, Bernd Wissinger, Rejko Krüger
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease. Science translational medicine 12 (560) (2021)
Sarah M Brooker, Dimitri Krainc
Glucocerebrosidase dysfunction in neurodegenerative disease. Essays in biochemistry (2021)
Lena F Burbulla, Sohee Jeon, Jianbin Zheng, Pingping Song, Richard B Silverman, Dimitri Krainc
A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson's disease. Science translational medicine 11 (514) (2020)
Jianbin Zheng, Sohee Jeon, Weilan Jiang, Lena F Burbulla, Daniel Ysselstein, Kristine Oevel, Dimitri Krainc, Richard B Silverman
Correction to Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase. Journal of medicinal chemistry 62 (5) (2019)
Jianbin Zheng, Sohee Jeon, Weilan Jiang, Lena F Burbulla, Daniel Ysselstein, Kristine Oevel, Dimitri Krainc, Richard B Silverman
Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase. Journal of medicinal chemistry 62 (3) (2019)
Jianbin Zheng, Long Chen, Owen S Skinner, Daniel Ysselstein, Jonathan Remis, Peter Lansbury, Renato Skerlj, Michael Mrosek, Ursula Heunisch, Stephan Krapp, Joel Charrow, Michael Schwake, Michael P Snyder, Richard B Silverman, Dimitri Krainc
β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site. Journal of the American Chemical Society 140 (18) (2018)
Lena F Burbulla, Pingping Song, Joseph R Mazzulli, Enrico Zampese, Yvette C Wong, Sohee Jeon, David P Santos, Judith Blanz, Carolin D Obermaier, Chelsee Strojny, Jeffrey N Savas, Evangelos Kiskinis, Xiaoxi Zhuang, Rejko Krüger, D James Surmeier, Dimitri Krainc
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science (New York, N.Y.) 357 (6357) (2017)