Dongmei Zhao

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Topics

Molecular Docking

Tyrosine Kinase

Chronic Myeloid Leukemia

Top Venues

RSC medicinal chemistry

Journal of medicinal chemistry

Archiv der Pharmazie

Molecules (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Haoyu Zhang, Jinyu Yu, Ziheng Yang, Zhiqiang Guo, Rui Liu, Qiaohua Qin, Yixiang Sun, Nian Liu, Zixuan Gao, Dongmei Zhao, Mao-Sheng Cheng
Structure-based virtual screening discovers novel PKMYT1 inhibitors. RSC medicinal chemistry 15 (9) (2024)
Yixiang Sun, Zixuan Gao, Ruifeng Wang, Guoqi Zhang, Tianxiao Wu, Wenbo Yin, Yin Sun, Qiaohua Qin, Dongmei Zhao, Maosheng Cheng
Design, synthesis, and biological evaluation of diaminopyrimidine derivatives as novel focal adhesion kinase inhibitors. RSC medicinal chemistry 14 (11) (2023)
Yin Sun, Yanli Xue, Hongbing Liu, Shuyi Mu, Pengkun Sun, Yu Sun, Lin Wang, Hanxun Wang, Jingkai Wang, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Huali Yang, Dongmei Zhao, Maosheng Cheng
Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid Leukemia. Journal of medicinal chemistry 66 (4) (2023)
Yin Sun, Yanli Xue, Hongbing Liu, Shuyi Mu, Pengkun Sun, Yu Sun, Lin Wang, Hanxun Wang, Jingkai Wang, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Huali Yang, Dongmei Zhao, Maosheng Cheng
Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid Leukemia. Journal of medicinal chemistry 66 (4) (2023)
Yin Sun, Yanli Xue, Hongbing Liu, Shuyi Mu, Pengkun Sun, Yu Sun, Lin Wang, Hanxun Wang, Jingkai Wang, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Huali Yang, Dongmei Zhao, Maosheng Cheng
Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid Leukemia. Journal of medicinal chemistry 66 (4) (2023)
Yanli Xue, Shuyi Mu, Pengkun Sun, Yin Sun, Nian Liu, Yu Sun, Lin Wang, Dongmei Zhao, Maosheng Cheng
Design, synthesis, and biological evaluation of novel pyrimidin-2-amine derivatives as potent PLK4 inhibitors. RSC medicinal chemistry 14 (9) (2023)
Yin Sun, Yanli Xue, Hongbing Liu, Shuyi Mu, Pengkun Sun, Yu Sun, Lin Wang, Hanxun Wang, Jingkai Wang, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Huali Yang, Dongmei Zhao, Maosheng Cheng
Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid Leukemia. Journal of medicinal chemistry (2023)
Yin Sun, Yanli Xue, Pengkun Sun, Shuyi Mu, Hongbing Liu, Yu Sun, Lin Wang, Jingkai Wang, Tianxiao Wu, Wenbo Yin, Qiaohua Qin, Yixiang Sun, Nian Liu, Hanxun Wang, Huali Yang, Dongmei Zhao, Maosheng Cheng
Discovery of the First Potent, Selective, and In Vivo Efficacious Polo-like Kinase 4 Proteolysis Targeting Chimera Degrader for the Treatment of TRIM37 -Amplified Breast Cancer. Journal of medicinal chemistry (2023)
Zixuan Gao, Jiachen Zhang, Kejian Li, Yixiang Sun, Xudong Wu, Guoqi Zhang, Rongrong Liu, Rui Liu, Dongmei Zhao, Maosheng Cheng
Design, synthesis and evaluation of 2-phenylpyrimidine derivatives as novel antifungal agents targeting CYP51. RSC medicinal chemistry 15 (2) (2023)
Zixuan Gao, Jiachen Zhang, Kejian Li, Yixiang Sun, Xudong Wu, Guoqi Zhang, Rongrong Liu, Rui Liu, Dongmei Zhao, Maosheng Cheng
Design, synthesis and evaluation of 2-phenylpyrimidine derivatives as novel antifungal agents targeting CYP51. RSC medicinal chemistry 15 (2) (2023)
Lin Wang, Yu Sun, Jingkai Wang, Yanli Xue, Yin Sun, Qiaohua Qin, Yixiang Sun, Dongmei Zhao, Maosheng Cheng
Design, synthesis, and biological evaluation of a potent PLK4 inhibitor WY29 with 1H-pyrazolo[3,4-d]pyrimidine scaffold. Archiv der Pharmazie (2022)
Nian Liu, Xin Wang, Qinglin Fu, Qiaohua Qin, Tianxiao Wu, Ruicheng Lv, Dongmei Zhao, Maosheng Cheng
Design, synthesis and biological evaluation of pyrazolo[3,4- b ]pyridine derivatives as TRK inhibitors. RSC medicinal chemistry 14 (1) (2022)
Lei Liu, Yixiang Sun, Zixuan Gao, Wenbo Yin, Hong Jiang, Tianxiao Wu, Yin Sun, Qiaohua Qin, Dongmei Zhao, Maosheng Cheng
Design, synthesis, and evaluation of novel 3,4-isoxazolediamide derivatives for the combination treatment of azole-resistant candidiasis. Archiv der Pharmazie 355 (12) (2022)
Nian Liu, Xin Wang, Qinglin Fu, Qiaohua Qin, Tianxiao Wu, Ruicheng Lv, Dongmei Zhao, Maosheng Cheng
Design, synthesis and biological evaluation of pyrazolo[3,4- b ]pyridine derivatives as TRK inhibitors. RSC medicinal chemistry 14 (1) (2022)
Bowen Yang, Haoran Zhang, Na Li, Lixin Gao, Hong Jiang, Weijuan Kan, Haoxing Yuan, Jia Li, Dongmei Zhao, Bing Xiong, Yubo Zhou, Dong Guo, Tongchao Liu
Discovery of Novel N -(5-(Pyridin-3-yl)-1 H -indazol-3-yl)benzamide Derivatives as Potent Cyclin-Dependent Kinase 7 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease. Journal of medicinal chemistry 65 (23) (2022)
Wenbo Yin, Tianxiao Wu, Lei Liu, Hong Jiang, Yuxin Zhang, Hengxian Cui, Yin Sun, Qiaohua Qin, Yixiang Sun, Zixuan Gao, Liyu Zhao, Xin Su, Dongmei Zhao, Mao-Sheng Cheng
Species-Selective Targeting of Fungal Hsp90: Design, Synthesis, and Evaluation of Novel 4,5-Diarylisoxazole Derivatives for the Combination Treatment of Azole-Resistant Candidiasis. Journal of medicinal chemistry 65 (7) (2022)
Ruicheng Lv, Xin Wang, Yixiang Sun, Qiaohua Qin, Nian Liu, Tianxiao Wu, Yin Sun, Wenbo Yin, Dongmei Zhao, Maosheng Cheng
Design, synthesis, and biological evaluation of aminopyridine derivatives as novel tropomyosin receptor kinase inhibitors. Archiv der Pharmazie (2022)
Yixiang Sun, Ruicheng Lv, Tianxiao Wu, Xiangyu Zhang, Yin Sun, Jiangkun Yan, Ziheng Zhang, Dongmei Zhao, Maosheng Cheng
Design, synthesis, and biological evaluation of coumarin analogs as novel LSD1 inhibitors. Archiv der Pharmazie (2021)
Jiangkun Yan, Yanting Gu, Yixiang Sun, Ziheng Zhang, Xiangyu Zhang, Xinran Wang, Tianxiao Wu, Dongmei Zhao, Maosheng Cheng
Design, synthesis, and biological evaluation of 5-aminotetrahydroquinoline-based LSD1 inhibitors acting on Asp375. Archiv der Pharmazie 354 (8) (2021)
Jihui Li, Tianxiao Wu, Xinjing Song, Yang Zheng, Jiaxin Meng, Qiaohua Qin, Yong-Xiang Liu, Dongmei Zhao, Maosheng Cheng
Studies on asymmetric total synthesis of (-)-β-hydrastine via a chiral epoxide ring-opening cascade cyclization strategy. RSC advances 10 (32) (2020)
Qiaohua Qin, Tianxiao Wu, Wenbo Yin, Yixiang Sun, Xiangyu Zhang, Ruifeng Wang, Jing Guo, Dongmei Zhao, Maosheng Cheng
Discovery of 2,4-diaminopyrimidine derivatives targeting p21-activated kinase 4: Biological evaluation and docking studies. Archiv der Pharmazie 353 (10) (2020)
Jihui Li, Yong-Xiang Liu, Xinjing Song, Tianxiao Wu, Jiaxin Meng, Yang Zheng, Qiaohua Qin, Dongmei Zhao, Maosheng Cheng
An Acid-Catalyzed Epoxide Ring-Opening/Transesterification Cascade Cyclization to Diastereoselective Syntheses of (±)-β-Noscapine and (±)-β-Hydrastine. Organic letters 21 (17) (2019)
Tianxiao Wu, Yu Pang, Jing Guo, Wenbo Yin, Mingyue Zhu, Chenzhou Hao, Kai Wang, Jian Wang, Dongmei Zhao, Maosheng Cheng
Discovery of 2-(4-Substituted-piperidin/piperazine-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-quinazoline-2,4-diamines as PAK4 Inhibitors with Potent A549 Cell Proliferation, Migration, and Invasion Inhibition Activity. Molecules (Basel, Switzerland) 23 (2) (2018)
Xinran Wang, Lijuan Hao, Xuanqi Xu, Wei Li, Chunchi Liu, Dongmei Zhao, Maosheng Cheng
Design, Synthesis and Biological Evaluation of N,N-Substituted Amine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors. Molecules (Basel, Switzerland) 22 (10) (2017)
Xinran Wang, Xuehua Lin, Xuanqi Xu, Wei Li, Lijuan Hao, Chunchi Liu, Dongmei Zhao, Maosheng Cheng
Design, Synthesis, and Biological Evaluation of N,N-Disubstituted-4-Arylthiazole-2-Methylamine Derivatives as Cholesteryl Ester Transfer Inhibitors. Molecules (Basel, Switzerland) 22 (11) (2017)