Dong Guo

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 30

Top Venues

Journal of medicinal chemistry

Nature communications

Chemical science

British journal of pharmacology

Xuzhou Medical University

Universiteit Leiden (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Xuzhou Medical University Sep 30 2015

China

Professor :: School of Pharmacy

Universiteit Leiden Jan 12 2014 - Feb 01 2016

Netherlands

Postdoc :: Medicinal Chemistry

Education History

Universiteit Leiden Jan 11 2010 - Jun 25 2014

Netherlands

PHD :: Medicinal Chemistry

Publications

Xiaochun Xiong, Naiyuan Wang, Yixiao Zhang, Wenchao Zhao, Ningning Pang, Kequan Fu, Nan Zhou, Xueyan Zhou, Dong Guo
Long-Residence Time Peptide Antagonist for the Vasopressin V 2 Receptor to Treat Autosomal Dominant Polycystic Kidney Disease. Journal of medicinal chemistry (2024)
Xiaochun Xiong, Naiyuan Wang, Yixiao Zhang, Wenchao Zhao, Ningning Pang, Kequan Fu, Nan Zhou, Xueyan Zhou, Dong Guo
Long-Residence Time Peptide Antagonist for the Vasopressin V 2 Receptor to Treat Autosomal Dominant Polycystic Kidney Disease. Journal of medicinal chemistry 67 (7) (2024)
Guohui Cheng, Shuang Tao, Shuang Liu, Ping Wang, Chi Zhang, Jin Liu, Chuanchuan Hao, Sheng Wang, Dong Guo, Bo Xu
Glutathione-Responsive Polymersome with Continuous Glutathione Depletion for Enhanced Photodynamic Therapy and Hypoxia-Activated Chemotherapy. ACS macro letters 13 (5) (2024)
Long Yin, Jiajia Li, Changhui Wu, Haoran Zhang, Wenchao Zhao, Zhiyuan Fan, Mengxuan Liu, Siqi Zhang, Mengzhe Guo, Xiaowei Dou, Dong Guo
Asymmetric synthesis of P-stereogenic phosphindane oxides via kinetic resolution and their biological activity. Nature communications 15 (1) (2024)
Pei Xu, Hao-Qiang Jiang, Hui Xu, Sai Wang, Hui-Xian Jiang, Song-Lei Zhu, Long Yin, Dong Guo, Xu Zhu
Photocatalytic deuterocarboxylation of alkynes with oxalate. Chemical science 15 (32) (2024)
Xiaochun Xiong, Naiyuan Wang, Yixiao Zhang, Wenchao Zhao, Ningning Pang, Kequan Fu, Nan Zhou, Xueyan Zhou, Dong Guo
Long-Residence Time Peptide Antagonist for the Vasopressin V 2 Receptor to Treat Autosomal Dominant Polycystic Kidney Disease. Journal of medicinal chemistry 67 (7) (2024)
Pei Xu, Hao-Qiang Jiang, Hui Xu, Sai Wang, Hui-Xian Jiang, Song-Lei Zhu, Long Yin, Dong Guo, Xu Zhu
Photocatalytic deuterocarboxylation of alkynes with oxalate. Chemical science 15 (32) (2024)
Long Yin, Jiajia Li, Changhui Wu, Haoran Zhang, Wenchao Zhao, Zhiyuan Fan, Mengxuan Liu, Siqi Zhang, Mengzhe Guo, Xiaowei Dou, Dong Guo
Asymmetric synthesis of P-stereogenic phosphindane oxides via kinetic resolution and their biological activity. Nature communications 15 (1) (2024)
Long Yin, Jiajia Li, Changhui Wu, Haoran Zhang, Wenchao Zhao, Zhiyuan Fan, Mengxuan Liu, Siqi Zhang, Mengzhe Guo, Xiaowei Dou, Dong Guo
Asymmetric synthesis of P-stereogenic phosphindane oxides via kinetic resolution and their biological activity. Nature communications 15 (1) (2024)
Guohui Cheng, Shuang Tao, Shuang Liu, Ping Wang, Chi Zhang, Jin Liu, Chuanchuan Hao, Sheng Wang, Dong Guo, Bo Xu
Glutathione-Responsive Polymersome with Continuous Glutathione Depletion for Enhanced Photodynamic Therapy and Hypoxia-Activated Chemotherapy. ACS macro letters (2024)
Xudong Cao, Peng Wang, Wenchao Zhao, Haoxing Yuan, Hongtao Hu, Ting Chen, Yixiao Zhang, Ying Ren, Limin Su, Kequan Fu, Hongli Liu, Dong Guo
Structure-Affinity and Structure-Kinetic Relationship Studies of Benzodiazepine Derivatives for the Development of Efficacious Vasopressin V 2 Receptor Antagonists. Journal of medicinal chemistry 66 (5) (2023)
Zhuang Miao, Yuhan Zhong, Yu Gan, Kequan Fu, Wencheng Liu, Zhihua Cao, Tiantian Zhao, Ziyuan Li, Ao Hai, Yanlai Peng, Zeping Zuo, Tian Zhang, Shilong Hu, Chunxia Chen, Ting Kang, Tianguang Huang, Dong Guo, Bowen Ke
A Novel Bifunctional μOR Agonist and σ 1 R Antagonist with Potent Analgesic Responses and Reduced Adverse Effects. Journal of medicinal chemistry (2023)
Yinan Wang, Yan He, Xiaojiao Ye, Yixiao Zhang, Xiuxiu Huang, Hongli Liu, Wenqing Dong, Dongzhi Yang, Dong Guo
Target immobilization on glass microfiber membranes as a label-free strategy for hit identification. Analytical and bioanalytical chemistry (2023)
Xudong Cao, Peng Wang, Wenchao Zhao, Haoxing Yuan, Hongtao Hu, Ting Chen, Yixiao Zhang, Ying Ren, Limin Su, Kequan Fu, Hongli Liu, Dong Guo
Structure-Affinity and Structure-Kinetic Relationship Studies of Benzodiazepine Derivatives for the Development of Efficacious Vasopressin V 2 Receptor Antagonists. Journal of medicinal chemistry 66 (5) (2023)
Nan Sun, Kexin Yang, Wenzhong Yan, Mingyue Yao, Chengcheng Yu, Wenwen Duan, Xiaoke Gu, Dong Guo, Hualiang Jiang, Chengying Xie, Jianjun Cheng
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response. Journal of medicinal chemistry (2023)
Xudong Cao, Peng Wang, Wenchao Zhao, Haoxing Yuan, Hongtao Hu, Ting Chen, Yixiao Zhang, Ying Ren, Limin Su, Kequan Fu, Hongli Liu, Dong Guo
Structure-Affinity and Structure-Kinetic Relationship Studies of Benzodiazepine Derivatives for the Development of Efficacious Vasopressin V 2 Receptor Antagonists. Journal of medicinal chemistry 66 (5) (2023)
Xudong Cao, Peng Wang, Wenchao Zhao, Haoxing Yuan, Hongtao Hu, Ting Chen, Yixiao Zhang, Ying Ren, Limin Su, Kequan Fu, Hongli Liu, Dong Guo
Structure-Affinity and Structure-Kinetic Relationship Studies of Benzodiazepine Derivatives for the Development of Efficacious Vasopressin V 2 Receptor Antagonists. Journal of medicinal chemistry (2023)
Hongli Liu, Haoran Zhang, Adriaan P IJzerman, Dong Guo
The translational perspective of ligand-receptor binding kinetics in drug discovery. British journal of pharmacology (2023)
Nan Sun, Kexin Yang, Wenzhong Yan, Mingyue Yao, Chengcheng Yu, Wenwen Duan, Xiaoke Gu, Dong Guo, Hualiang Jiang, Chengying Xie, Jianjun Cheng
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response. Journal of medicinal chemistry (2023)
Dandan Zhong, Zhikang Wan, Jie Cai, Lingling Quan, Rumeng Zhang, Tian Teng, Hang Gao, Chenyu Fan, Meng Wang, Dong Guo, Hongxing Zhang, Zhanjun Jia, Ying Sun
mPGES-2 blockade antagonizes β-cell senescence to ameliorate diabetes by acting on NR4A1. Nature metabolism 4 (2) (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry 66 (2) (2022)
Pei Xu, Xing-Yu Wang, Zhijuan Wang, Jinjin Zhao, Xu-Dong Cao, Xiao-Chun Xiong, Yu-Chao Yuan, Songlei Zhu, Dong Guo, Xu Zhu
Defluorinative Alkylation of Trifluoromethylbenzimidazoles Enabled by Spin-Center Shift: A Synergistic Photocatalysis/Thiol Catalysis Process with CO 2 • . Organic letters 24 (22) (2022)
Bowen Yang, Haoran Zhang, Na Li, Lixin Gao, Hong Jiang, Weijuan Kan, Haoxing Yuan, Jia Li, Dongmei Zhao, Bing Xiong, Yubo Zhou, Dong Guo, Tongchao Liu
Discovery of Novel N -(5-(Pyridin-3-yl)-1 H -indazol-3-yl)benzamide Derivatives as Potent Cyclin-Dependent Kinase 7 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease. Journal of medicinal chemistry 65 (23) (2022)
Xudong Cao, Peng Wang, Haoxing Yuan, Haoran Zhang, Yan He, Kequan Fu, Qian Fang, Hongli Liu, Limin Su, Long Yin, Pei Xu, Yuyang Xie, Xiaochun Xiong, Junqi Wang, Xu Zhu, Dong Guo
Benzodiazepine Derivatives as Potent Vasopressin V 2 Receptor Antagonists for the Treatment of Autosomal Dominant Kidney Disease. Journal of medicinal chemistry 65 (13) (2022)
Haoran Zhang, Wenzhong Yan, Yongzhan Sun, Haoxing Yuan, Limin Su, Xudong Cao, Peng Wang, Zhou Xu, Youhui Hu, Zhongjian Wang, Yinan Wang, Kequan Fu, Ying Sun, Yupeng Chen, Jianjun Cheng, Dong Guo
Long Residence Time at the Vasopressin V 2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease. Journal of medicinal chemistry 65 (11) (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry 66 (2) (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry 66 (2) (2022)
Limin Su, Haoxing Yuan, Haoran Zhang, Ruoqi Wang, Kequan Fu, Long Yin, Ying Ren, Hongli Liu, Qian Fang, Junqi Wang, Dong Guo
PF-06409577 inhibits renal cyst progression by concurrently inhibiting the mTOR pathway and CFTR channel activity. FEBS open bio 12 (10) (2022)
Dong Guo, Lambertus A Peletier, Lloyd Bridge, Wesley Keur, Henk de Vries, Annelien Zweemer, Laura H Heitman, Adriaan P IJzerman
A two-state model for the kinetics of competitive radioligand binding. British journal of pharmacology 175 (10) (2018)

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Publication Activity (10 Years)

Top Topics

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Dong Guo