Mao-Sheng Cheng (Maosheng Cheng)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 47

Top Topics

Molecular Dynamics

Top Venues

Journal of medicinal chemistry

The Journal of organic chemistry

Organic letters

Physical chemistry chemical physics : PCCP

This page only lists publications with an associated author ORCID identifier.

Publications

Gang Xing, Zhenli Li, Zhengxing Zhi, Ce Yi, Ruiwen Zhang, Huali Yang, Yuyang Zhang, Bin Lin, Yang Liu, Li Pan, Mao-Sheng Cheng
Discovery and Identification of Novel 5-Hydroxy-4 H -benzo[1,4]oxazin-3-one Derivatives as Potent β 2 -Adrenoceptor Agonists through Structure-Based Design, Synthesis, and Biological Evaluation. Journal of medicinal chemistry (2024)
Hanxun Wang, Zhuo Qi, Wenxiong Lian, Lanyan Ma, Shizhun Wang, Haihan Liu, Yu Jin, Huali Yang, Jian Wang, Mao-Sheng Cheng
Application of molecular dynamics-based pharmacophore and machine learning approaches to identify novel Mcl1 inhibitors through drug repurposing and mechanics research. Physical chemistry chemical physics : PCCP (2024)
Haihan Liu, Baichun Hu, Peiying Chen, Xiao Wang, Hanxun Wang, Shizhun Wang, Jian Wang, Bin Lin, Mao-Sheng Cheng
Docking Score ML: Target-Specific Machine Learning Models Improving Docking-Based Virtual Screening in 155 Targets. Journal of chemical information and modeling (2024)
Hanxun Wang, Zhuo Qi, Wenxiong Lian, Lanyan Ma, Shizhun Wang, Haihan Liu, Yu Jin, Huali Yang, Jian Wang, Mao-Sheng Cheng
Application of molecular dynamics-based pharmacophore and machine learning approaches to identify novel Mcl1 inhibitors through drug repurposing and mechanics research. Physical chemistry chemical physics : PCCP 26 (22) (2024)
Haihan Liu, Baichun Hu, Peiying Chen, Xiao Wang, Hanxun Wang, Shizhun Wang, Jian Wang, Bin Lin, Mao-Sheng Cheng
Docking Score ML: Target-Specific Machine Learning Models Improving Docking-Based Virtual Screening in 155 Targets. Journal of chemical information and modeling 64 (14) (2024)
Ye Zhong, Jing Xu, Ruochen Zhou, Li Tang, Shaoyue Ding, Zhaohui Ren, Ning Song, Baichun Hu, Huali Yang, Yili Sun, Mao-Sheng Cheng, Jia Li, Yang Liu
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation. Journal of medicinal chemistry (2024)
Jiang Zhu, Lu Yang, Hairui Liu, Shitao Sun, Jiaji Li, Lianjie Zhang, Hanyang Sun, Mao-Sheng Cheng, Bin Lin, Yong-Xiang Liu
Syntheses of Tetracyclic Indoline Derivatives Via Gold(I)-Catalyzed Hydroamination/Cycloisomerization Cascade of 2-Ethynyltryptamides. The Journal of organic chemistry 89 (5) (2024)
Kaitong Zhuang, Graham C Haug, Yangyang Wang, Shuyu Yin, Huiying Sun, Siwen Huang, Ramon Trevino, Kunzhi Shen, Yao Sun, Chao Huang, Bin Qin, Yong-Xiang Liu, Mao-Sheng Cheng, Oleg V Larionov, Shengfei Jin
Cobalt-Catalyzed Carbon-Heteroatom Transfer Enables Regioselective Tricomponent 1,4-Carboamination. Journal of the American Chemical Society 146 (12) (2024)
Gang Xing, Zhenli Li, Zhengxing Zhi, Ce Yi, Ruiwen Zhang, Huali Yang, Yuyang Zhang, Bin Lin, Yang Liu, Li Pan, Mao-Sheng Cheng
Discovery and Identification of Novel 5-Hydroxy-4 H -benzo[1,4]oxazin-3-one Derivatives as Potent β 2 -Adrenoceptor Agonists through Structure-Based Design, Synthesis, and Biological Evaluation. Journal of medicinal chemistry 67 (4) (2024)
Tianheng Cheng, Nihan Wang, Rui Wen, Shizhun Wang, Haoyu Zhang, Mao-Sheng Cheng
Discovery of non-sulfonamide carbonic anhydrase IX inhibitors through structure-based virtual screening. Physical chemistry chemical physics : PCCP 26 (11) (2024)
Jiang Zhu, Jianghao Yan, Fudong Wang, Lianjie Zhang, Jiaji Li, Mao-Sheng Cheng, Lu Yang, Yong-Xiang Liu
Gold-Catalyzed Oxidative Rearrangement Strategy to Yield 2-Hydroxycyclohepta-1,3-diene-1-carbonyl Compounds. The Journal of organic chemistry 89 (12) (2024)
Ye Zhong, Jing Xu, Ruochen Zhou, Li Tang, Shaoyue Ding, Zhaohui Ren, Ning Song, Baichun Hu, Huali Yang, Yili Sun, Mao-Sheng Cheng, Jia Li, Yang Liu
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation. Journal of medicinal chemistry 67 (6) (2024)
Jiang Zhu, Jianghao Yan, Fudong Wang, Lianjie Zhang, Jiaji Li, Mao-Sheng Cheng, Lu Yang, Yong-Xiang Liu
Gold-Catalyzed Oxidative Rearrangement Strategy to Yield 2-Hydroxycyclohepta-1,3-diene-1-carbonyl Compounds. The Journal of organic chemistry (2024)
Tianheng Cheng, Nihan Wang, Rui Wen, Shizhun Wang, Haoyu Zhang, Mao-Sheng Cheng
Discovery of non-sulfonamide carbonic anhydrase IX inhibitors through structure-based virtual screening. Physical chemistry chemical physics : PCCP 26 (11) (2024)
Haoyu Zhang, Jinyu Yu, Ziheng Yang, Zhiqiang Guo, Rui Liu, Qiaohua Qin, Yixiang Sun, Nian Liu, Zixuan Gao, Dongmei Zhao, Mao-Sheng Cheng
Structure-based virtual screening discovers novel PKMYT1 inhibitors. RSC medicinal chemistry 15 (9) (2024)
Ting Wang, Yueting Hua, Fangbo Deng, Rui Wen, Haoyu Zhang, Chunshi Li, Yang Liu, Mao-Sheng Cheng
Scalable Synthesis of the Key Fexuprazan Intermediate and Investigation of a Reaction Mechanism. ACS omega 9 (36) (2024)
Jiang Zhu, Lu Yang, Hairui Liu, Shitao Sun, Jiaji Li, Lianjie Zhang, Hanyang Sun, Mao-Sheng Cheng, Bin Lin, Yong-Xiang Liu
Syntheses of Tetracyclic Indoline Derivatives Via Gold(I)-Catalyzed Hydroamination/Cycloisomerization Cascade of 2-Ethynyltryptamides. The Journal of organic chemistry (2024)
Xinyue Jiang, Yuchao Yan, Huali Yang, Mao-Sheng Cheng, Deqiang Dou, Yang Liu
Design, synthesis and activity evaluation of arctigenin derivatives with HDAC inhibition activity. RSC advances 14 (13) (2024)
Tianheng Cheng, Nihan Wang, Rui Wen, Shizhun Wang, Haoyu Zhang, Mao-Sheng Cheng
Discovery of non-sulfonamide carbonic anhydrase IX inhibitors through structure-based virtual screening. Physical chemistry chemical physics : PCCP (2024)
Ye Zhong, Jing Xu, Ruochen Zhou, Li Tang, Shaoyue Ding, Zhaohui Ren, Ning Song, Baichun Hu, Huali Yang, Yili Sun, Mao-Sheng Cheng, Jia Li, Yang Liu
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation. Journal of medicinal chemistry 67 (6) (2024)
Gang Xing, Zhenli Li, Zhengxing Zhi, Ce Yi, Ruiwen Zhang, Huali Yang, Yuyang Zhang, Bin Lin, Yang Liu, Li Pan, Mao-Sheng Cheng
Discovery and Identification of Novel 5-Hydroxy-4 H -benzo[1,4]oxazin-3-one Derivatives as Potent β 2 -Adrenoceptor Agonists through Structure-Based Design, Synthesis, and Biological Evaluation. Journal of medicinal chemistry 67 (4) (2024)
Shenglin Wang, Dongyan Feng, Weirenbo Wang, Chao Zheng, Chaowei Liang, Siqing Li, Haonan Li, Fanxing Xu, Hao Cao, Hui-Ming Hua, Mao-Sheng Cheng, Da-Hong Li
Discovery of SIRT1-Activating Hydrogen Sulfide Donating Derivatives for Efficient Resistant of Myocardial Ischemic Injury. Journal of medicinal chemistry (2024)
Kaitong Zhuang, Graham C Haug, Yangyang Wang, Shuyu Yin, Huiying Sun, Siwen Huang, Ramon Trevino, Kunzhi Shen, Yao Sun, Chao Huang, Bin Qin, Yong-Xiang Liu, Mao-Sheng Cheng, Oleg V Larionov, Shengfei Jin
Cobalt-Catalyzed Carbon-Heteroatom Transfer Enables Regioselective Tricomponent 1,4-Carboamination. Journal of the American Chemical Society (2024)
Xinyue Jiang, Yuchao Yan, Huali Yang, Mao-Sheng Cheng, Deqiang Dou, Yang Liu
Design, synthesis and activity evaluation of arctigenin derivatives with HDAC inhibition activity. RSC advances 14 (13) (2024)
Lu Yang, Anbin Hou, Qing Jiang, Mao-Sheng Cheng, Yong-Xiang Liu
Methodological Development and Applications of Tryptamine-Ynamide Cyclizations in Synthesizing Core Skeletons of Indole Alkaloids. The Journal of organic chemistry (2023)
Jiang Zhu, Jiaji Li, Lianjie Zhang, Shitao Sun, Lu Yang, Jiayue Fu, Hanyang Sun, Mao-Sheng Cheng, Bin Lin, Yong-Xiang Liu
Gold(I)-Catalyzed Substitution-Controlled Syntheses of Spiro[indoline-3,3 ' -pyrrolidine] and Spiro[indoline-3,3 ' -piperidine] Derivatives. The Journal of organic chemistry (2023)
Ruoxi Sang, Renming Fan, Aohua Deng, Jiakui Gou, Ruizhuo Lin, Ting Zhao, Yongrui Hai, Junke Song, Yang Liu, Bing Qi, Guanhua Du, Mao-Sheng Cheng, Gaofei Wei
Degradation of Hexokinase 2 Blocks Glycolysis and Induces GSDME-Dependent Pyroptosis to Amplify Immunogenic Cell Death for Breast Cancer Therapy. Journal of medicinal chemistry (2023)
Zenghui Sun, Xinhang Zhang, Jiayue Fu, Lianjie Zhang, Mao-Sheng Cheng, Lu Yang, Yong-Xiang Liu
Collective Syntheses of 8-Oxoprotoberberines via Sequential In(OTf) 3 -Catalyzed Cyclization and Pd(OAc) 2 -Catalyzed Heck Coupling. The Journal of organic chemistry (2023)
Jiang Zhu, Jiaji Li, Lianjie Zhang, Shitao Sun, Zhaobo Wang, Xiang Li, Lu Yang, Mao-Sheng Cheng, Bin Lin, Yong-Xiang Liu
Quantum Mechanical Prediction and Experimental Verification of Au(I)-Catalyzed Substitution-Controlled Syntheses of 1 H -Pyrido[4,3- b ]indole and Spiro[indoline-3,3'-pyridine] Derivatives. The Journal of organic chemistry (2023)
Zhenbin Han, Dongmei Feng, Wenxuan Wang, Yue Wang, Mao-Sheng Cheng, Huali Yang, Yang Liu
Influence of Fatty Acid Modification on the Anticancer Activity of the Antimicrobial Peptide Figainin 1. ACS omega 8 (44) (2023)
Renming Fan, Aohua Deng, Bing Qi, Shuo Zhang, Ruoxi Sang, Lanxin Luo, Jiakui Gou, Yongqing Liu, Ruizhuo Lin, Minggao Zhao, Yang Liu, Le Yang, Mao-Sheng Cheng, Gaofei Wei
CJ 2 : A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane. Journal of medicinal chemistry 66 (1) (2023)
Renming Fan, Aohua Deng, Bing Qi, Shuo Zhang, Ruoxi Sang, Lanxin Luo, Jiakui Gou, Yongqing Liu, Ruizhuo Lin, Minggao Zhao, Yang Liu, Le Yang, Mao-Sheng Cheng, Gaofei Wei
CJ 2 : A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane. Journal of medicinal chemistry 66 (1) (2023)
Renming Fan, Aohua Deng, Bing Qi, Shuo Zhang, Ruoxi Sang, Lanxin Luo, Jiakui Gou, Yongqing Liu, Ruizhuo Lin, Minggao Zhao, Yang Liu, Le Yang, Mao-Sheng Cheng, Gaofei Wei
CJ 2 : A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane. Journal of medicinal chemistry (2023)
Renming Fan, Aohua Deng, Bing Qi, Shuo Zhang, Ruoxi Sang, Lanxin Luo, Jiakui Gou, Yongqing Liu, Ruizhuo Lin, Minggao Zhao, Yang Liu, Le Yang, Mao-Sheng Cheng, Gaofei Wei
CJ 2 : A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane. Journal of medicinal chemistry 66 (1) (2023)
Xinhang Zhang, Hanyang Sun, Changhong Han, He Wang, Junpeng Zhang, Di Zhang, Bin Lin, Hui-Ming Hua, Mao-Sheng Cheng, Yong-Xiang Liu
Asymmetric Total Synthesis of Neobraclactone C. Organic letters 24 (51) (2022)
Jingfu Zhang, Sen Zhang, Zhixing Ding, Anbin Hou, Jiayue Fu, Hongwei Su, Mao-Sheng Cheng, Bin Lin, Lu Yang, Yong-Xiang Liu
Gold(I)-Catalyzed Tandem Intramolecular Methoxylation/Double Aldol Condensation Strategy Yielding 2,2'-Spirobi[indene] Derivatives. Organic letters 24 (37) (2022)
Xinhang Zhang, Hanyang Sun, Changhong Han, He Wang, Junpeng Zhang, Di Zhang, Bin Lin, Hui-Ming Hua, Mao-Sheng Cheng, Yong-Xiang Liu
Asymmetric Total Synthesis of Neobraclactone C. Organic letters 24 (51) (2022)
Xincheng Lin, Jiawei Cheng, Yuming Wu, Yaoliang Zhang, Hailun Jiang, Jian Wang, Xuejun Wang, Mao-Sheng Cheng
Identification and In Silico Binding Study of a Highly Potent DENV NS2B-NS3 Covalent Inhibitor. ACS medicinal chemistry letters 13 (4) (2022)
Gang Xing, Da-Hong Li, Anthony Yiu-Ho Woo, Zhengxing Zhi, Lei Ji, Ruijuan Xing, Hailiang Lv, Bin He, Hui An, Haiyan Zhao, Bin Lin, Li Pan, Mao-Sheng Cheng
Discovery of a Highly Selective β 2 -Adrenoceptor Agonist with a 2-Amino-2-phenylethanol Scaffold as an Oral Antiasthmatic Agent. Journal of medicinal chemistry 65 (7) (2022)
Xiaonan Li, Gang Xing, Xinxin Guo, Yang Wang, Zixia Hu, Mao-Sheng Cheng, Ying Peng, Jiang Zheng
Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity. Chemical research in toxicology 35 (6) (2022)
Jiayue Fu, Bingbing Li, Xinxiu Wang, He Wang, Minghui Deng, Huali Yang, Bin Lin, Mao-Sheng Cheng, Lu Yang, Yong-Xiang Liu
Collective Total Syntheses of Benzo[ c ]phenanthridine Alkaloids via a Sequential Transition Metal-Catalyzed Pot-Economic Approach. Organic letters 24 (45) (2022)
Xinhang Zhang, Hanyang Sun, Changhong Han, He Wang, Junpeng Zhang, Di Zhang, Bin Lin, Hui-Ming Hua, Mao-Sheng Cheng, Yong-Xiang Liu
Asymmetric Total Synthesis of Neobraclactone C. Organic letters 24 (51) (2022)
Xinhang Zhang, Hanyang Sun, Changhong Han, He Wang, Junpeng Zhang, Di Zhang, Bin Lin, Hui-Ming Hua, Mao-Sheng Cheng, Yong-Xiang Liu
Asymmetric Total Synthesis of Neobraclactone C. Organic letters (2022)
Wenbo Yin, Tianxiao Wu, Lei Liu, Hong Jiang, Yuxin Zhang, Hengxian Cui, Yin Sun, Qiaohua Qin, Yixiang Sun, Zixuan Gao, Liyu Zhao, Xin Su, Dongmei Zhao, Mao-Sheng Cheng
Species-Selective Targeting of Fungal Hsp90: Design, Synthesis, and Evaluation of Novel 4,5-Diarylisoxazole Derivatives for the Combination Treatment of Azole-Resistant Candidiasis. Journal of medicinal chemistry 65 (7) (2022)
Lu Yang, Siwen Huang, Rongkang Huang, Anbin Hou, Sen Zhang, Hongwei Su, Xiaohong Ding, Bin Lin, Mao-Sheng Cheng, Yong-Xiang Liu
Total Syntheses of Aspidospermidine, N-Methylaspidospermidine, N-Acetylaspidospermidine, and Aspidospermine via a Tandem Cyclization of Tryptamine-Ynamide. Organic letters 23 (16) (2021)
Gang Xing, Anthony Yiu-Ho Woo, Li Pan, Bin Lin, Mao-Sheng Cheng
Recent Advances in β2-Agonists for Treatment of Chronic Respiratory Diseases and Heart Failure. Journal of medicinal chemistry 63 (24) (2020)
Xiangyu Zhang, Hailun Jiang, Wei Li, Jian Wang, Mao-Sheng Cheng
Computational Insight into Protein Tyrosine Phosphatase 1B Inhibition: A Case Study of the Combined Ligand- and Structure-Based Approach. Computational and mathematical methods in medicine 2017 (2017)