Eric L Nuermberger (Eric Nuermberger)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 42

Top Topics

Mild Traumatic Brain Injury

Methicillin Resistant Staphylococcus Aureus

Top Venues

Antimicrobial agents and chemotherapy

Nature communications

Nature medicine

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Eric L Nuermberger, Richard E Chaisson
Restocking the tuberculosis drug arsenal. Nature medicine (2024)
Si-Yang Li, Sandeep Tyagi, Heena Soni, Fabrice Betoudji, Paul J Converse, Khisimuzi Mdluli, Anna M Upton, Nader Fotouhi, David Barros Aguirre, Lluís Ballell, Elena Jimenez-Navarro, Eric L Nuermberger
Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis. Antimicrobial agents and chemotherapy 68 (4) (2024)
Si-Yang Li, Sandeep Tyagi, Heena Soni, Fabrice Betoudji, Paul J Converse, Khisimuzi Mdluli, Anna M Upton, Nader Fotouhi, David Barros Aguirre, Lluís Ballell, Elena Jimenez-Navarro, Eric L Nuermberger
Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis. Antimicrobial agents and chemotherapy (2024)
Eric L Nuermberger, Richard E Chaisson
Restocking the tuberculosis drug arsenal. Nature medicine 30 (3) (2024)
Natasha Strydom, Jacqueline P Ernest, Marjorie Imperial, Belen P Solans, Qianwen Wang, Rokeya Tasneen, Sandeep Tyagi, Heena Soni, Andrew Garcia, Kristina Bigelow, Martin Gengenbacher, Matthew Zimmerman, Min Xie, Jansy P Sarathy, Tian J Yang, Veronique Anne Dartois, Eric L Nuermberger, Radojka M Savic
Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen. Nature communications 15 (1) (2024)
Janice J N Goh, Qianwen Wang, Nan Zhang, Niurys de Castro Suarez, Annamarie E Bustion, Eric L Nuermberger, Radojka M Savic
Prospectively predicting BPaMZ phase IIb/III trial outcomes using a translational mouse-to-human platform. Antimicrobial agents and chemotherapy (2024)
Si-Yang Li, Sandeep Tyagi, Heena Soni, Fabrice Betoudji, Paul J Converse, Khisimuzi Mdluli, Anna M Upton, Nader Fotouhi, David Barros Aguirre, Lluís Ballell, Elena Jimenez-Navarro, Eric L Nuermberger
Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis. Antimicrobial agents and chemotherapy 68 (4) (2024)
Eric L Nuermberger, Richard E Chaisson
Restocking the tuberculosis drug arsenal. Nature medicine 30 (3) (2024)
Natasha Strydom, Jacqueline P Ernest, Marjorie Imperial, Belen P Solans, Qianwen Wang, Rokeya Tasneen, Sandeep Tyagi, Heena Soni, Andrew Garcia, Kristina Bigelow, Martin Gengenbacher, Matthew Zimmerman, Min Xie, Jansy P Sarathy, Tian J Yang, Veronique Anne Dartois, Eric L Nuermberger, Radojka M Savic
Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen. Nature communications 15 (1) (2024)
Natasha Strydom, Jacqueline P Ernest, Marjorie Imperial, Belen P Solans, Qianwen Wang, Rokeya Tasneen, Sandeep Tyagi, Heena Soni, Andrew Garcia, Kristina Bigelow, Martin Gengenbacher, Matthew Zimmerman, Min Xie, Jansy P Sarathy, Tian J Yang, Veronique Anne Dartois, Eric L Nuermberger, Radojka M Savic
Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen. Nature communications 15 (1) (2024)
Si-Yang Li, Sandeep Tyagi, Heena Soni, Fabrice Betoudji, Paul J Converse, Khisimuzi Mdluli, Anna M Upton, Nader Fotouhi, David Barros Aguirre, Lluís Ballell, Elena Jimenez-Navarro, Eric L Nuermberger
Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis. Antimicrobial agents and chemotherapy 68 (4) (2024)
Deepak Almeida, Si-Yang Li, Jin Lee, Barry Hafkin, Khisimuzi Mdluli, Nader Fotouhi, Eric L Nuermberger
Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis. Antimicrobial agents and chemotherapy (2023)
Yong S Chang, Si-Yang Li, Henry Pertinez, Fabrice Betoudji, Jin Lee, Steven P Rannard, Andrew Owen, Eric L Nuermberger, Nicole C Ammerman
Using dynamic oral dosing of rifapentine and rifabutin to simulate exposure profiles of long-acting formulations in a mouse model of tuberculosis preventive therapy. bioRxiv : the preprint server for biology (2023)
Si-Yang Li, Paul J Converse, Fabrice Betoudji, Jin Lee, Khisimuzi Mdluli, Anna Upton, Nader Fotouhi, Eric L Nuermberger
Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model. Antimicrobial agents and chemotherapy (2023)
Yong S Chang, Si-Yang Li, Henry Pertinez, Fabrice Betoudji, Jin Lee, Steven P Rannard, Andrew Owen, Eric L Nuermberger, Nicole C Ammerman
Using Dynamic Oral Dosing of Rifapentine and Rifabutin to Simulate Exposure Profiles of Long-Acting Formulations in a Mouse Model of Tuberculosis Preventive Therapy. Antimicrobial agents and chemotherapy (2023)
Jian Xu, Dongshuo Li, Jinghua Shi, Bin Wang, Fei Ge, Zhenyong Guo, Xiaopan Mu, Eric L Nuermberger, Yu Lu
Bedquiline Resistance Mutations: Correlations with Drug Exposures and Impact on the Proteome in M. tuberculosis. Antimicrobial agents and chemotherapy (2023)
Jacqueline P Ernest, Janice Jia Ni Goh, Natasha Strydom, Qianwen Wang, Rob Christiaan van Wijk, Nan Zhang, Amelia Deitchman, Eric L Nuermberger, Radojka M Savic
Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs. The European respiratory journal (2023)
Deepak V Almeida, Paul J Converse, Eric L Nuermberger
Mutations in Rv0678 Reduce Susceptibility of Mycobacterium tuberculosis to the DprE1 Inhibitor TBA-7371. Antimicrobial agents and chemotherapy 67 (3) (2023)
Yong S Chang, Si-Yang Li, Henry Pertinez, Fabrice Betoudji, Jin Lee, Steven P Rannard, Andrew Owen, Eric L Nuermberger, Nicole C Ammerman
Using dynamic oral dosing of rifapentine and rifabutin to simulate exposure profiles of long-acting formulations in a mouse model of tuberculosis preventive therapy. bioRxiv : the preprint server for biology (2023)
Deepak V Almeida, Paul J Converse, Eric L Nuermberger
Mutations in Rv0678 Reduce Susceptibility of Mycobacterium tuberculosis to the DprE1 Inhibitor TBA-7371. Antimicrobial agents and chemotherapy 67 (3) (2023)
Yong S Chang, Si-Yang Li, Henry Pertinez, Fabrice Betoudji, Jin Lee, Steven P Rannard, Andrew Owen, Eric L Nuermberger, Nicole C Ammerman
Using dynamic oral dosing of rifapentine and rifabutin to simulate exposure profiles of long-acting formulations in a mouse model of tuberculosis preventive therapy. bioRxiv : the preprint server for biology (2023)
Deepak V Almeida, Paul J Converse, Eric L Nuermberger
Mutations in Rv0678 Reduce Susceptibility of Mycobacterium tuberculosis to the DprE1 Inhibitor TBA-7371. Antimicrobial agents and chemotherapy (2023)
Deepak V Almeida, Paul J Converse, Eric L Nuermberger
Mutations in Rv0678 Reduce Susceptibility of Mycobacterium tuberculosis to the DprE1 Inhibitor TBA-7371. Antimicrobial agents and chemotherapy 67 (3) (2023)
Deepak V Almeida, Paul J Converse, Eric L Nuermberger
Mutations in Rv0678 Reduce Susceptibility of Mycobacterium tuberculosis to the DprE1 Inhibitor TBA-7371. Antimicrobial agents and chemotherapy 67 (3) (2023)
Oren Gordon, Dustin A Dikeman, Roger V Ortines, Yu Wang, Christine Youn, Mohammed Mumtaz, Nicholas Orlando, Jeffrey Zhang, Aman M Patel, Ethan Gough, Amit Kaushik, Eric L Nuermberger, Anna M Upton, Nader Fotouhi, Lloyd S Miller, Nathan K Archer
The Novel Oxazolidinone TBI-223 Is Effective in Three Preclinical Mouse Models of Methicillin-Resistant Staphylococcus aureus Infection. Microbiology spectrum 10 (5) (2022)
Natalia Kurepina, Liang Chen, Kaelea Composto, Dalin Rifat, Eric L Nuermberger, Barry N Kreiswirth
CRISPR Inhibition of Essential Peptidoglycan Biosynthesis Genes in Mycobacterium abscessus and Its Impact on β-Lactam Susceptibility. Antimicrobial agents and chemotherapy 66 (4) (2022)
Simon R Green, Susan H Davis, Sebastian Damerow, Curtis A Engelhart, Michael Mathieson, Beatriz Baragaña, David A Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K Tamaki, Kirsteen I Buchanan, John Post, Karen Dowers, Sharon M Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C Kim, James M Bean, Navid Nahiyaan, Kyu Y Rhee, Qinglan Wang, Vee Y Tan, Helena I M Boshoff, Paul J Converse, Si-Yang Li, Yong S Chang, Nader Fotouhi, Anna M Upton, Eric L Nuermberger, Dirk Schnappinger, Kevin D Read, Lourdes Encinas, Robert H Bates, Paul G Wyatt, Laura A T Cleghorn
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nature communications 13 (1) (2022)
Amit Kaushik, Nicole C Ammerman, Rokeya Tasneen, Sophie Lachau-Durand, Koen Andries, Eric L Nuermberger
Efficacy of Long-Acting Bedaquiline Regimens in a Mouse Model of Tuberculosis Preventive Therapy. American journal of respiratory and critical care medicine 205 (5) (2022)
Alexander Berg, James Clary, Debra Hanna, Eric L Nuermberger, Anne Lenaerts, Nicole C Ammerman, Michelle Ramey, Dan Hartley, David Hermann
Model-Based Meta-Analysis of Relapsing Mouse Model Studies from the Critical Path to Tuberculosis Drug Regimens Initiative Database. Antimicrobial agents and chemotherapy 66 (3) (2022)
Eric L Nuermberger, Maria Santos Martínez-Martínez, Olalla Sanz, Beatriz Urones, Jorge Esquivias, Heena Soni, Rokeya Tasneen, Sandeep Tyagi, Si-Yang Li, Paul J Converse, Helena I Boshoff, Gregory Thomas Robertson, Gurdyal S Besra, Katherine A Abrahams, Anna M Upton, Khisimuzi Mdluli, Gary W Boyle, Sam Turner, Nader Fotouhi, Nicholas C Cammack, Juan Miguel Siles, Marta Alonso, Jaime Escribano, Joel Lelievre, Joaquin Rullas-Trincado, Esther Pérez-Herrán, Robert H Bates, Gareth Maher-Edwards, David Barros Aguirre, Lluís Ballell, Elena Jiménez
GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment. Antimicrobial agents and chemotherapy 66 (6) (2022)
Binayak Rimal, Hunter R Batchelder, Elizabeth Story-Roller, Chandra M Panthi, Chavis Tabor, Eric L Nuermberger, Craig A Townsend, Gyanu Lamichhane
T405, a New Penem, Exhibits In Vivo Efficacy against M. abscessus and Synergy with β-Lactams Imipenem and Cefditoren. Antimicrobial agents and chemotherapy 66 (6) (2022)
Rokeya Tasneen, Andrew Garcia, Paul J Converse, Matthew D Zimmerman, Veronique Anne Dartois, Ekaterina Kurbatova, Andrew A Vernon, Wendy Carr, Jason E Stout, Kelly E Dooley, Eric L Nuermberger
Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models. Antimicrobial agents and chemotherapy 66 (4) (2022)
Christian Dide-Agossou, Allison A Bauman, Michelle E Ramey, Karen Rossmassler, Reem Al Mubarak, Samantha Pauly, Martin I Voskuil, Maria Garcia-Cremades, Radojka M Savic, Payam Nahid, Camille M Moore, Rokeya Tasneen, Eric L Nuermberger, Gregory Thomas Robertson, Nicholas D Walter
Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments. Antimicrobial agents and chemotherapy 66 (4) (2022)
Olumide Martins, Jin Lee, Amit Kaushik, Nicole C Ammerman, Kelly E Dooley, Eric L Nuermberger
In Vitro Activity of Bedaquiline and Imipenem against Actively Growing, Nutrient-Starved, and Intracellular Mycobacterium abscessus. Antimicrobial agents and chemotherapy 65 (12) (2021)
Jian Xu, Paul J Converse, Anna M Upton, Khisimuzi Mdluli, Nader Fotouhi, Eric L Nuermberger
Comparative Efficacy of the Novel Diarylquinoline TBAJ-587 and Bedaquiline against a Resistant Rv0678 Mutant in a Mouse Model of Tuberculosis. Antimicrobial agents and chemotherapy 65 (4) (2021)
Jin Lee, Nicole C Ammerman, Anusha Agarwal, Maram Naji, Si-Yang Li, Eric L Nuermberger
Differential In Vitro Activities of Individual Drugs and Bedaquiline-Rifabutin Combinations against Actively Multiplying and Nutrient-Starved Mycobacterium abscessus. Antimicrobial agents and chemotherapy 65 (2) (2021)
Oliver Komm, Deepak V Almeida, Paul J Converse, Till F Omansen, Eric L Nuermberger
Impact of Dose, Duration, and Immune Status on Efficacy of Ultrashort Telacebec Regimens in Mouse Models of Buruli Ulcer. Antimicrobial agents and chemotherapy 65 (11) (2021)
Deepak Almeida, Paul J Converse, Si-Yang Li, Anna M Upton, Nader Fotouhi, Eric L Nuermberger
Comparative Efficacy of the Novel Diarylquinoline TBAJ-876 and Bedaquiline against a Resistant Rv0678 Mutant in a Mouse Model of Tuberculosis. Antimicrobial agents and chemotherapy 65 (12) (2021)
Kendra K Radtke, Jacqueline P Ernest, Nan Zhang, Nicole C Ammerman, Eric L Nuermberger, Robert Belknap, Rosanna Boyd, Timothy R Sterling, Radojka M Savic
Comparative Efficacy of Rifapentine Alone and in Combination with Isoniazid for Latent Tuberculosis Infection: a Translational Pharmacokinetic-Pharmacodynamic Modeling Study. Antimicrobial agents and chemotherapy 65 (12) (2021)
Kristina M Bigelow, Rokeya Tasneen, Yong S Chang, Kelly E Dooley, Eric L Nuermberger
Preserved Efficacy and Reduced Toxicity with Intermittent Linezolid Dosing in Combination with Bedaquiline and Pretomanid in a Murine Tuberculosis Model. Antimicrobial agents and chemotherapy 64 (10) (2020)
Dalin Rifat, Si-Yang Li, Thomas Ioerger, Keshav Shah, Jean-Philippe Lanoix, Jin Lee, Ghader Bashiri, James Sacchettini, Eric L Nuermberger
Mutations in fbiD (Rv2983) as a Novel Determinant of Resistance to Pretomanid and Delamanid in Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy 65 (1) (2020)
Nicole C Ammerman, Rosemary V Swanson, Elaine M Bautista, Deepak V Almeida, Vikram Saini, Till F Omansen, Haidan Guo, Yong Seok Chang, Si-Yang Li, Asa Tapley, Rokeya Tasneen, Sandeep Tyagi, Fabrice Betoudji, Chivonne Moodley, Bongani Ngcobo, Logan Pillay, Linda A Bester, Sanil D Singh, Richard E Chaisson, Eric L Nuermberger, Jacques H Grosset
Impact of Clofazimine Dosing on Treatment Shortening of the First-Line Regimen in a Mouse Model of Tuberculosis. Antimicrobial agents and chemotherapy 62 (7) (2018)