Helena I M Boshoff (Helena I Boshoff)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 37

Top Venues

ACS infectious diseases

Journal of medicinal chemistry

Journal of the American Chemical Society

RSC medicinal chemistry

National Institutes of Health

University of the Witwatersrand (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Institutes of Health

United States

Associate Staff Scientist :: Laboratory of Clinical Microbiology and Immunology

Education History

University of the Witwatersrand

South Africa

PHD :: Molecular Mycobacteriology

Publications

Darean Bague, Ruiqin Wang, Dana Hodge, Marwa O Mikati, Jose S Roma, Helena I M Boshoff, Allyson L Dailey, Misgina Girma, Robin D Couch, Audrey R Odom John, Cynthia S Dowd
Inhibition of DXR in the MEP pathway with lipophilic N -alkoxyaryl FR900098 analogs. RSC medicinal chemistry 15 (7) (2024)
Darean Bague, Ruiqin Wang, Dana Hodge, Marwa O Mikati, Jose S Roma, Helena I M Boshoff, Allyson L Dailey, Misgina Girma, Robin D Couch, Audrey R Odom John, Cynthia S Dowd
Inhibition of DXR in the MEP pathway with lipophilic N -alkoxyaryl FR900098 analogs. RSC medicinal chemistry 15 (7) (2024)
Darean Bague, Ruiqin Wang, Dana Hodge, Marwa O Mikati, Jose S Roma, Helena I M Boshoff, Allyson L Dailey, Misgina Girma, Robin D Couch, Audrey R Odom John, Cynthia S Dowd
Inhibition of DXR in the MEP pathway with lipophilic N -alkoxyaryl FR900098 analogs. RSC medicinal chemistry 15 (7) (2024)
Helena I M Boshoff, Katherine Young, Yong-Mo Ahn, Veena D Yadav, Brendan M Crowley, Lihu Yang, Jing Su, Sangmi Oh, Kriti Arora, Jenna Andrews, Michelle Manikkam, Michelle Sutphin, Anthony J Smith, Danielle M Weiner, Michaela K Piazza, Joel D Fleegle, Felipe Gomez, Emmannual K Dayao, Brendan Prideaux, Matthew Zimmerman, Firat Kaya, Jansy Sarathy, Vee Yang Tan, Laura E Via, Richard Tschirret-Guth, Anne J Lenaerts, Gregory T Robertson, Veronique Anne Dartois, David B Olsen, Clifton Earl Barry
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities. ACS infectious diseases (2024)
Helena I M Boshoff, Katherine Young, Yong-Mo Ahn, Veena D Yadav, Brendan M Crowley, Lihu Yang, Jing Su, Sangmi Oh, Kriti Arora, Jenna Andrews, Michelle Manikkam, Michelle Sutphin, Anthony J Smith, Danielle M Weiner, Michaela K Piazza, Joel D Fleegle, Felipe Gomez, Emmannual K Dayao, Brendan Prideaux, Matthew Zimmerman, Firat Kaya, Jansy Sarathy, Vee Yang Tan, Laura E Via, Richard Tschirret-Guth, Anne J Lenaerts, Gregory T Robertson, Veronique Anne Dartois, David B Olsen, Clifton Earl Barry
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities. ACS infectious diseases 10 (5) (2024)
Helena I M Boshoff, Katherine Young, Yong-Mo Ahn, Veena D Yadav, Brendan M Crowley, Lihu Yang, Jing Su, Sangmi Oh, Kriti Arora, Jenna Andrews, Michelle Manikkam, Michelle Sutphin, Anthony J Smith, Danielle M Weiner, Michaela K Piazza, Joel D Fleegle, Felipe Gomez, Emmannual K Dayao, Brendan Prideaux, Matthew Zimmerman, Firat Kaya, Jansy Sarathy, Vee Yang Tan, Laura E Via, Richard Tschirret-Guth, Anne J Lenaerts, Gregory T Robertson, Veronique Anne Dartois, David B Olsen, Clifton Earl Barry
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities. ACS infectious diseases 10 (5) (2024)
Timm O Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I M Boshoff, Bertrand Beckert, Joanna C Evans, Jan Schlemmer, Becky Sloan, Danielle M Weiner, Laura E Via, Atica Moosa, Thomas R Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E Barry, Digby Francis Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N Wilson, Daniel Krug
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society (2023)
Simon R Green, Caroline Wilson, Thomas C Eadsforth, Avinash S Punekar, Fabio K Tamaki, Gavin Wood, Nicola Caldwell, Barbara Forte, Neil R Norcross, Michael Kiczun, John M Post, Eva Maria Lopez-Román, Curtis A Engelhart, Iva Lukac, Fabio Zuccotto, Ola Epemolu, Helena I M Boshoff, Dirk Schnappinger, Chris Walpole, Ian H Gilbert, Kevin D Read, Paul G Wyatt, Beatriz Baragaña
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity. Journal of medicinal chemistry (2023)
Timm O Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I M Boshoff, Bertrand Beckert, Joanna C Evans, Jan Schlemmer, Becky Sloan, Danielle M Weiner, Laura E Via, Atica Moosa, Thomas R Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E Barry, Digby Francis Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N Wilson, Daniel Krug
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society 145 (2) (2023)
Timm O Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I M Boshoff, Bertrand Beckert, Joanna C Evans, Jan Schlemmer, Becky Sloan, Danielle M Weiner, Laura E Via, Atica Moosa, Thomas R Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E Barry, Digby Francis Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N Wilson, Daniel Krug
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society 145 (2) (2023)
Timm O Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I M Boshoff, Bertrand Beckert, Joanna C Evans, Jan Schlemmer, Becky Sloan, Danielle M Weiner, Laura E Via, Atica Moosa, Thomas R Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E Barry, Digby Francis Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N Wilson, Daniel Krug
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society 145 (2) (2023)
Veena D Yadav, Helena I M Boshoff, Lena Trifonov, Jose Santinni O Roma, Thomas R Ioerger, Clifton E Barry, Sangmi Oh
Synthesis and Structure-Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents. ACS medicinal chemistry letters 14 (9) (2023)
Xu Wang, Rachel L Edwards, Haley S Ball, Kenneth M Heidel, Robert C Brothers, Claire Johnson, Amanda Haymond, Misgina Girma, Allyson Dailey, Jose Santinni Roma, Helena I M Boshoff, Damon M Osbourn, Marvin J Meyers, Robin D Couch, Audrey R Odom John, Cynthia S Dowd
MEPicides: α,β-unsaturated Fosmidomycin N -Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase. ACS infectious diseases (2023)
Timm O Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I M Boshoff, Bertrand Beckert, Joanna C Evans, Jan Schlemmer, Becky Sloan, Danielle M Weiner, Laura E Via, Atica Moosa, Thomas R Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E Barry, Digby Francis Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N Wilson, Daniel Krug
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society 145 (2) (2023)
Timm O Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I M Boshoff, Bertrand Beckert, Joanna C Evans, Jan Schlemmer, Becky Sloan, Danielle M Weiner, Laura E Via, Atica Moosa, Thomas R Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E Barry, Digby Francis Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N Wilson, Daniel Krug
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society 145 (2) (2023)
Timm O Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I M Boshoff, Bertrand Beckert, Joanna C Evans, Jan Schlemmer, Becky Sloan, Danielle M Weiner, Laura E Via, Atica Moosa, Thomas R Ioerger, Michael Graf, Boris Zinshteyn, Maha Abdelshahid, Fabian Nguyen, Stefan Arenz, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Rachel Green, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E Barry, Digby Francis Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N Wilson, Daniel Krug
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society 145 (2) (2023)
Melissa D Chengalroyen, Mandy K Mason, Alessandro Borsellini, Raffaella Tassoni, Garth L Abrahams, Sasha Lynch, Yong-Mo Ahn, Jon Ambler, Katherine Young, Brendan M Crowley, David B Olsen, Digby Francis Warner, Clifton E Barry Iii, Helena I M Boshoff, Meindert H Lamers, Valerie Mizrahi
DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis . ACS infectious diseases 8 (3) (2022)
Ben S Gold, Jun Zhang, Landys Lopez Quezada, Julia Roberts, Yan Ling, Madeleine Wood, Wasima Shinwari, Laurent Goullieux, Christine Roubert, Laurent Fraisse, Eric Bacqué, Sophie Lagrange, Bruno Filoche-Rommé, Michal Vieth, Philip A Hipskind, Louis N Jungheim, Jeffrey Aubé, Sarah M Scarry, Stacey L McDonald, Kelin Li, Andrew Perkowski, Quyen Nguyen, Veronique Anne Dartois, Matthew Zimmerman, David B Olsen, Katherine Young, Shilah Bonnett, Douglas Joerss, Tanya Parish, Helena I M Boshoff, Kriti Arora, Clifton E Barry, Laura Guijarro, Sara Anca, Joaquín Rullas, Beatriz Rodríguez-Salguero, Maria S Martínez-Martínez, Esther Porras-De Francisco, Mónica Cacho, David Barros Aguirre, Paul W Smith, Steven J Berthel, Carl Nathan, Robert H Bates
Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions. ACS infectious diseases 8 (3) (2022)
Simon R Green, Susan H Davis, Sebastian Damerow, Curtis A Engelhart, Michael Mathieson, Beatriz Baragaña, David A Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K Tamaki, Kirsteen I Buchanan, John Post, Karen Dowers, Sharon M Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C Kim, James M Bean, Navid Nahiyaan, Kyu Y Rhee, Qinglan Wang, Vee Y Tan, Helena I M Boshoff, Paul J Converse, Si-Yang Li, Yong S Chang, Nader Fotouhi, Anna M Upton, Eric L Nuermberger, Dirk Schnappinger, Kevin D Read, Lourdes Encinas, Robert H Bates, Paul G Wyatt, Laura A T Cleghorn
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nature communications 13 (1) (2022)
Michael J Pepi, Shibin Chacko, Gary M Marqus, Vinayak Singh, Zhe Wang, Kyle Planck, Ryan T Cullinane, Penchala N Meka, Deviprasad R Gollapalli, Thomas R Ioerger, Kyu Y Rhee, Gregory D Cuny, Helena I M Boshoff, Lizbeth Hedstrom
A d-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of Mycobacterium tuberculosis . ACS infectious diseases 8 (2) (2022)
Bree B Aldridge, David Barros-Aguirre, Clifton Earl Barry, Robert H Bates, Steven J Berthel, Helena I M Boshoff, Kelly Chibale, Xin-Jie Chu, Christopher B Cooper, Veronique Anne Dartois, Ken Duncan, Nader Fotouhi, Fabian Gusovsky, Philip A Hipskind, Dale J Kempf, Joël Lelièvre, Anne J Lenaerts, Case W MacNamara, Valerie Mizrahi, Carl Nathan, David B Olsen, Tanya Parish, H Michael Petrassi, Alexander Pym, Kyu Y Rhee, Gregory T Robertson, Jeremy Michael Rock, Eric J Rubin, Betsy Russell, David G Russell, James C Sacchettini, Dirk Schnappinger, Michael Schrimpf, Anna M Upton, Peter Warner, Paul Graham Wyatt, Ying Yuan
The Tuberculosis Drug Accelerator at year 10: what have we learned? Nature medicine 27 (8) (2021)
Shibin Chacko, Helena I M Boshoff, Vinayak Singh, Davide M Ferraris, Deviprasad R Gollapalli, Minjia Zhang, Ann P Lawson, Michael J Pepi, Andrzej Joachimiak, Menico Rizzi, Valerie Mizrahi, Gregory D Cuny, Lizbeth Hedstrom
Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents. Journal of medicinal chemistry (2021)
Candice Soares de Melo, Vinayak Singh, Alissa Myrick, Sandile B Simelane, Dale Taylor, Christel Brunschwig, Nina Lawrence, Dirk Schnappinger, Curtis A Engelhart, Anuradha Kumar, Tanya Parish, Qin Su, Timothy G Myers, Helena I M Boshoff, Clifton E Barry, Frederick A Sirgel, Paul D van Helden, Kirsteen I Buchanan, Tracy Bayliss, Simon R Green, Peter C Ray, Paul G Wyatt, Gregory S Basarab, Charles J Eyermann, Kelly Chibale, Sandeep R Ghorpade
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies. Journal of medicinal chemistry 64 (1) (2021)
Sangmi Oh, M Daben J Libardo, Shaik Azeeza, Gary T Pauly, Jose Santinni O Roma, Andaleeb Sajid, Yoshitaka Tateishi, Caroline Duncombe, Michael Goodwin, Thomas R Ioerger, Paul G Wyatt, Peter C Ray, David W Gray, Helena I M Boshoff, Clifton Earl Barry
Structure-Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents. ACS infectious diseases 7 (2) (2021)
Vitor Mendes, Simon R Green, Joanna C Evans, Jeannine Hess, Michal Blaszczyk, Christina Spry, Owain Bryant, James Cory-Wright, Daniel S-H Chan, Pedro H M Torres, Zhe Wang, Navid Nahiyaan, Sandra O'Neill, Sebastian Damerow, John Post, Tracy Bayliss, Sasha L Lynch, Anthony G Coyne, Peter C Ray, Chris Abell, Kyu Y Rhee, Helena I M Boshoff, Clifton Earl Barry, Valerie Mizrahi, Paul G Wyatt, Thomas L Blundell
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nature communications 12 (1) (2021)
Lutete Peguy Khonde, Rudolf Müller, Grant A Boyle, Virsinha Reddy, Aloysius T Nchinda, Charles J Eyermann, Stephen Fienberg, Vinayak Singh, Alissa Myrick, Efrem Abay, Mathew Njoroge, Nina Lawrence, Qin Su, Timothy G Myers, Helena I M Boshoff, Clifton E Barry, Frederick A Sirgel, Paul D van Helden, Lisa M Massoudi, Gregory T Robertson, Anne J Lenaerts, Gregory S Basarab, Sandeep R Ghorpade, Kelly Chibale
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis. Journal of medicinal chemistry 64 (17) (2021)
Joanna C Evans, Dinakaran Murugesan, John M Post, Vitor Mendes, Zhe Wang, Navid Nahiyaan, Sasha L Lynch, Stephen Thompson, Simon R Green, Peter C Ray, Jeannine Hess, Christina Spry, Anthony G Coyne, Chris Abell, Helena I M Boshoff, Paul G Wyatt, Kyu Y Rhee, Tom L Blundell, Clifton E Barry, Valerie Mizrahi
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity. ACS infectious diseases 7 (6) (2021)
Yanlin Jian, He Eun Forbes, Fabian Hulpia, Martijn D P Risseeuw, Guy Caljon, Hélène Munier-Lehmann, Helena I M Boshoff, Serge Van Calenbergh
2-((3,5-Dinitrobenzyl)thio)quinazolinones: Potent Antimycobacterial Agents Activated by Deazaflavin (F420)-Dependent Nitroreductase (Ddn). Journal of medicinal chemistry 64 (1) (2020)
Qinglan Wang, Helena I M Boshoff, Justin R Harrison, Peter C Ray, Simon R Green, Paul G Wyatt, Clifton Earl Barry
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis. Science (New York, N.Y.) 367 (6482) (2020)
Andrew J Whitehouse, Sherine E Thomas, Karen P Brown, Alexander Fanourakis, Daniel S-H Chan, M Daben J Libardo, Vitor Mendes, Helena I M Boshoff, R Andres Floto, Chris Abell, Tom L Blundell, Anthony G Coyne
Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches. Journal of medicinal chemistry 62 (15) (2019)
Tiago Beites, Kathryn O'Brien, Divya Tiwari, Curtis A Engelhart, Shaun Walters, Jenna Andrews, Hee-Jeong Yang, Michelle L Sutphen, Danielle M Weiner, Emmanuel K Dayao, Matthew Zimmerman, Brendan Prideaux, Prashant V Desai, Thierry Masquelin, Laura E Via, Véronique Dartois, Helena I M Boshoff, Clifton Earl Barry, Sabine Ehrt, Dirk Schnappinger
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development. Nature communications 10 (1) (2019)
Andrew J Whitehouse, M Daben J Libardo, Monica Kasbekar, Paul D Brear, Gerhard Fischer, Craig J Thomas, Clifton E Barry, Helena I M Boshoff, Anthony G Coyne, Chris Abell
Targeting of Fumarate Hydratase from Mycobacterium tuberculosis Using Allosteric Inhibitors with a Dimeric-Binding Mode. Journal of medicinal chemistry 62 (23) (2019)
Matthew R Bockman, Curtis A Engelhart, Julia D Cramer, Michael D Howe, Neeraj K Mishra, Matthew Zimmerman, Peter Larson, Nadine Alvarez-Cabrera, Sae Woong Park, Helena I M Boshoff, James M Bean, Victor G Young, David M Ferguson, Veronique Dartois, Joseph T Jarrett, Dirk Schnappinger, Courtney C Aldrich
Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase. ACS infectious diseases 5 (4) (2019)
Xu Wang, Rachel L Edwards, Haley Ball, Claire Johnson, Amanda Haymond, Misgina Girma, Michelle Manikkam, Robert C Brothers, Kyle T McKay, Stacy D Arnett, Damon M Osbourn, Sophie Alvarez, Helena I M Boshoff, Marvin J Meyers, Robin D Couch, Audrey R Odom John, Cynthia S Dowd
MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria. Journal of medicinal chemistry 61 (19) (2018)
Shibin Chacko, Helena I M Boshoff, Vinayak Singh, Davide M Ferraris, Deviprasad R Gollapalli, Minjia Zhang, Ann P Lawson, Michael J Pepi, Andrzej Joachimiak, Menico Rizzi, Valerie Mizrahi, Gregory D Cuny, Lizbeth Hedstrom
Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents. Journal of medicinal chemistry 61 (11) (2018)
Sangmi Oh, Yumi Park, Curtis A Engelhart, Joshua B Wallach, Dirk Schnappinger, Kriti Arora, Michelle Manikkam, Brian Gac, Hongwu Wang, Nicholas Murgolo, David B Olsen, Michael Goodwin, Michelle Sutphin, Danielle M Weiner, Laura E Via, Helena I M Boshoff, Clifton Earl Barry
Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase. Journal of medicinal chemistry 61 (22) (2018)
Dinakaran Murugesan, Peter C Ray, Tracy Bayliss, Gareth A Prosser, Justin R Harrison, Kirsteen Green, Candice Soares de Melo, Tzu-Shean Feng, Leslie J Street, Kelly Chibale, Digby F Warner, Valerie Mizrahi, Ola Epemolu, Paul Scullion, Lucy Ellis, Jennifer Riley, Yoko Shishikura, Liam Ferguson, Maria Osuna-Cabello, Kevin D Read, Simon R Green, Dirk A Lamprecht, Peter M Finin, Adrie J C Steyn, Thomas R Ioerger, Jim Sacchettini, Kyu Y Rhee, Kriti Arora, Clifton Earl Barry, Paul G Wyatt, Helena I M Boshoff
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization. ACS infectious diseases 4 (6) (2018)

Helena I M Boshoff.css-eqlu8i{font-size:small;padding-left:4px;} (Helena I Boshoff)

Publication Activity (10 Years)

Top Topics

Top Venues

Helena I M Boshoff (Helena I Boshoff)