Eric S Lightcap (Eric Lightcap)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 6

Top Topics

Tyrosine Kinase

Endoplasmic Reticulum

Immune Response

Top Venues

Journal of medicinal chemistry

Clinical cancer research : an official journal of the American Association for Cancer Research

Nature communications

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Christopher G Thomson, Thomas D Aicher, Weiwei Cheng, Hongwen Du, Crissy Dudgeon, An-Hu Li, Baozhong Li, Eric S Lightcap, Diheng Luo, Mark Mulvihill, Pengwei Pan, Benjamin F Rahemtulla, Alan C Rigby, Bradley Sherborne, Sanjeev Sood, David Surguladze, Eric P A Talbot, Feven Tameire, Simon Taylor, Yi Wang, Paulina Wojnarowicz, Fenfen Xiao, Savithri Ramurthy
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator. Journal of medicinal chemistry 67 (7) (2024)
Christopher G Thomson, Thomas D Aicher, Weiwei Cheng, Hongwen Du, Crissy Dudgeon, An-Hu Li, Baozhong Li, Eric S Lightcap, Diheng Luo, Mark Mulvihill, Pengwei Pan, Benjamin F Rahemtulla, Alan C Rigby, Bradley Sherborne, Sanjeev Sood, David Surguladze, Eric P A Talbot, Feven Tameire, Simon Taylor, Yi Wang, Paulina Wojnarowicz, Fenfen Xiao, Savithri Ramurthy
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator. Journal of medicinal chemistry (2024)
Christopher G Thomson, Thomas D Aicher, Weiwei Cheng, Hongwen Du, Crissy Dudgeon, An-Hu Li, Baozhong Li, Eric S Lightcap, Diheng Luo, Mark Mulvihill, Pengwei Pan, Benjamin F Rahemtulla, Alan C Rigby, Bradley Sherborne, Sanjeev Sood, David Surguladze, Eric P A Talbot, Feven Tameire, Simon Taylor, Yi Wang, Paulina Wojnarowicz, Fenfen Xiao, Savithri Ramurthy
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator. Journal of medicinal chemistry 67 (7) (2024)
Tomoko Yamamori Morita, Jie Yu, Yukie Kashima, Ryo Kamata, Gaku Yamamoto, Tatsunori Minamide, Chiaki Mashima, Miyuki Yoshiya, Yuta Sakae, Toyohiro Yamauchi, Yumi Hakozaki, Shun-Ichiro Kageyama, Akito Nakamura, Eric S Lightcap, Kosuke Tanaka, Huifeng Niu, Karuppiah Kannan, Akihiro Ohashi
CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockade. Nature communications 14 (1) (2023)
Michael E Stokes, Veronica Calvo, Sho Fujisawa, Crissy Dudgeon, Sharon Huang, Nupur Ballal, Leyi Shen, Jennifer Gasparek, Matthew Betzenhauser, Simon J Taylor, Kirk A Staschke, Alan C Rigby, Mark J Mulvihill, Nandita Bose, Eric S Lightcap, David Surguladze
PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Eric S Lightcap, Pengfei Yu, Stephen Grossman, Keli Song, Mithun Khattar, Kristina Xega, Xingyue He, James M Gavin, Hisashi Imaichi, James J Garnsey, Erik Koenig, Hongru Zhang, Zhen Lu, Pooja Shah, Yu Fu, Michael A Milhollen, Beryl A Hatton, Jessica Riceberg, Vaishali Shinde, Cong Li, James Minissale, Xiaofeng Yang, Dylan England, Richard A Klinghoffer, Steven P Langston, Katherine Galvin, Gary Shapiro, Sai M Pulukuri, Serge Y Fuchs, Dennis Huszar
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models. Science translational medicine 13 (611) (2021)