Serge Y Fuchs

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 29

Top Topics

Induced Apoptosis

Endoplasmic Reticulum

Immune Response

Top Venues

Molecular cancer research : MCR

Nature communications

Science advances

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR 22 (4) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR 22 (4) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR 22 (4) (2024)
Fan Yang, Md Naushad Akhtar, Duo Zhang, Rakan El-Mayta, Junyoung Shin, Jay F Dorsey, Lin Zhang, George X Xu, Wei Guo, Stephen J Bagley, Serge Y Fuchs, Constantinos Koumenis, Justin D Lathia, Michael J Mitchell, Yanqing Gong, Yi Fan
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science advances 10 (9) (2024)
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Y Fuchs, J Alan Diehl
miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress. Molecular cancer research : MCR (2024)
Elizabeth L Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina M Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa S Carnevalli, Fernando J Calero-Nieto, Gemma N Jones, Andrew J Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J Carl Barrett, Arsene-Bienvenu Loembé, Serge Y Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A Nance, Carlos Alberto Gomez Roca, Elaine B Cadogan, Susan E Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I Gabrilovich, Simon T Barry
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment. Nature communications 15 (1) (2024)
Elizabeth L Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina M Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa S Carnevalli, Fernando J Calero-Nieto, Gemma N Jones, Andrew J Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J Carl Barrett, Arsene-Bienvenu Loembé, Serge Y Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A Nance, Carlos Alberto Gomez Roca, Elaine B Cadogan, Susan E Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I Gabrilovich, Simon T Barry
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment. Nature communications 15 (1) (2024)
Zhen Lu, Ioannis I Verginadis, Motofumi Kumazoe, Gerardo M Castillo, Yao Yao, Rebecca E Guerra, Sandra Bicher, Menghao You, George McClung, Rong Qiu, Zebin Xiao, Zhen Miao, Subin S George, Daniel P Beiting, Takashi Nojiri, Yasutake Tanaka, Yoshinori Fujimura, Hiroaki Onda, Yui Hatakeyama, Akiko Nishimoto-Ashfield, Katrina Bykova, Wei Guo, Yi Fan, Nikolay M Buynov, J Alan Diehl, Ben Z Stanger, Hirofumi Tachibana, Terence P F Gade, Ellen Puré, Constantinos Koumenis, Elijah M Bolotin, Serge Y Fuchs
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies. Science translational medicine 16 (761) (2024)
Elizabeth L Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina M Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa S Carnevalli, Fernando J Calero-Nieto, Gemma N Jones, Andrew J Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J Carl Barrett, Arsene-Bienvenu Loembé, Serge Y Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A Nance, Carlos Alberto Gomez Roca, Elaine B Cadogan, Susan E Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I Gabrilovich, Simon T Barry
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment. Nature communications 15 (1) (2024)
Charline Ogier, Akino Mercy Charles Solomon, Zhen Lu, Ludmila Recoules, Alena Klochkova, Linara Gabitova-Cornell, Battuya Bayarmagnai, Diana Restifo, Aizhan Surumbayeva, Debora Barbosa Vendramini-Costa, Alexander Y Deneka, Ralph Francescone, Anna C Lilly, Alyssa Sipman, Jaye C Gardiner, Tiffany Q Luong, Janusz Franco-Barraza, Nina Ibeme, Kathy Q Cai, Margret B Einarson, Emmanuelle Nicolas, Andrei Efimov, Emily Megill, Nathaniel W Snyder, Corinne Bousquet, Jerome Cros, Yunyun Zhou, Erica A Golemis, Bojana Gligorijevic, Jonathan Soboloff, Serge Y Fuchs, Edna Cukierman, Igor Astsaturov
Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6). bioRxiv : the preprint server for biology (2023)
Wei Guo, Wenqun Zhong, Zebin Xiao, Zhiyuan Qin, Jingbo Yang, Yi Wen, Ziyan Yu, Yumei Li, Neil C Sheppard, Serge Y Fuchs, George X Xu, Meenhard Herylyn, Carl H June, Ellen Puré
Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer research (2023)
Wenqun Zhong, Zebin Xiao, Zhiyuan Qin, Jingbo Yang, Yi Wen, Ziyan Yu, Yumei Li, Neil C Sheppard, Serge Y Fuchs, George X Xu, Meenhard Herylyn, Carl H June, Ellen Puré, Wei Guo
Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer research (2023)
Wenqun Zhong, Zebin Xiao, Zhiyuan Qin, Jingbo Yang, Yi Wen, Ziyan Yu, Yumei Li, Neil C Sheppard, Serge Y Fuchs, George X Xu, Meenhard Herylyn, Carl H June, Ellen Puré, Wei Guo
Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer research (2023)
Yongjuan Guan, Huijuan Lin, N Adrian Leu, Gordon Ruthel, Serge Y Fuchs, Luca Busino, Mengcheng Luo, P Jeremy Wang
SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic acids research 50 (9) (2022)
Hongru Zhang, Vivek S Tomar, Jinyang Li, Raghavendra Basavaraja, Fangxue Yan, Jun Gui, Noreen McBrearty, Tara Lee Costich, Daniel P Beiting, M Andres Blanco, José R Conejo-Garcia, Gurpanna Saggu, Allison J Berger, Yulia Nefedova, Dmitry I Gabrilovich, Serge Y Fuchs
Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment. Cancer immunology research 10 (12) (2022)
Zhen Lu, Jinyun Chen, Pengfei Yu, Matthew J Atherton, Jun Gui, Vivek S Tomar, Justin D Middleton, Neil T Sullivan, Sunil Singhal, Subin S George, Ashley G Woolfork, Aalim M Weiljie, Tsonwin Hai, Evgeniy B Eruslanov, Serge Y Fuchs
Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer. Nature communications 13 (1) (2022)
Bartosz Mucha, Shuo Qie, Sagar Bajpai, Vincenzo Tarallo, J Nathaniel Diehl, Frank Tedeschi, Gao Zhou, Zhaofeng Gao, Samuel P Flashner, Andres J Klein-Szanto, Hanina Hibshoosh, Shimonosono Masataka, Olga S Chajewski, Ireneusz Majsterek, Dariusz Pytel, Maria Hatzoglou, Channing J Der, Hiroshi Nakagawa, Adam J Bass, Kwok-Kin Wong, Serge Y Fuchs, Anil K Rustgi, Eckhard Jankowsky, J Alan Diehl
Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation. Nature communications 13 (1) (2022)
Hongru Zhang, Pengfei Yu, Vivek S Tomar, Xiangjie Chen, Matthew J Atherton, Zhen Lu, Hong-Guang Zhang, Shifeng Li, Angelica Ortiz, Jun Gui, N Adrian Leu, Fangxue Yan, Andres Blanco, Mirella L Meyer-Ficca, Ralph G Meyer, Daniel P Beiting, Jinyang Li, Selene Nunez-Cruz, Roddy S O'Connor, Lexus R Johnson, Andy J Minn, Subin S George, Constantinos Koumenis, J Alan Diehl, Michael C Milone, Hui Zheng, Serge Y Fuchs
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors. Nature cancer 3 (7) (2022)
Noreen McBrearty, Christina Cho, Jinyun Chen, Farima Zahedi, Amy R Peck, Enrico Radaelli, Charles-Antoine Assenmacher, Clarice Pavlak, Anne Devine, Pengfei Yu, Zhen Lu, Hongru Zhang, Jinyang Li, Jason R Pitarresi, Igor Astsaturov, Edna Cukierman, Anil K Rustgi, Ben Z Stanger, Hallgeir Rui, Serge Y Fuchs
Tumor suppressive and immune-stimulating roles of cholesterol 25-hydroxylase in pancreatic cancer cells. Molecular cancer research : MCR (2022)
Ioannis I Verginadis, Harris Avgousti, James Monslow, Giorgos Skoufos, Frank Chinga, Kyle Kim, Nektaria Maria Leli, Ilias V Karagounis, Brett I Bell, Anastasia Velalopoulou, Carlo Salas Salinas, Victoria S Wu, Yang Li, Jiangbin Ye, David A Scott, Andrei L Osterman, Arjun Sengupta, Aalim Weljie, Menggui Huang, Duo Zhang, Yi Fan, Enrico Radaelli, John W Tobias, Florian Rambow, Panagiotis Karras, Jean-Christophe Marine, Xiaowei Xu, Artemis G Hatzigeorgiou, Sandra W Ryeom, J Alan Diehl, Serge Y Fuchs, Ellen Puré, Constantinos Koumenis
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression. Nature cell biology 24 (6) (2022)
Kevin Alicea-Torres, Emilio Sanseviero, Jun Gui, Jinyun Chen, Filippo Veglia, Qiujin Yu, Laxminarasimha Donthireddy, Andrew Kossenkov, Cindy Lin, Shuyu Fu, Charles Mulligan, Brian Nam, Gregory Masters, Fred Denstman, Joseph Bennett, Neil Hockstein, Agnieszka Rynda-Apple, Yulia Nefedova, Serge Y Fuchs, Dmitry I Gabrilovich
Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway. Nature communications 12 (1) (2021)
Yunguang Sun, Ning Yang, Fransiscus E Utama, Sameer S Udhane, Junling Zhang, Amy R Peck, Alicia Yanac, Katherine Duffey, John F Langenheim, Vindhya Udhane, Guanjun Xia, Jess F Peterson, Julie M Jorns, Marja T Nevalainen, Romain Rouet, Peter Schofield, Daniel Christ, Christopher J Ormandy, Anne L Rosenberg, Inna Chervoneva, Shirng-Wern Tsaih, Michael J Flister, Serge Y Fuchs, Kay-Uwe Wagner, Hallgeir Rui
NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers. Science advances 7 (38) (2021)
Eric S Lightcap, Pengfei Yu, Stephen Grossman, Keli Song, Mithun Khattar, Kristina Xega, Xingyue He, James M Gavin, Hisashi Imaichi, James J Garnsey, Erik Koenig, Hongru Zhang, Zhen Lu, Pooja Shah, Yu Fu, Michael A Milhollen, Beryl A Hatton, Jessica Riceberg, Vaishali Shinde, Cong Li, James Minissale, Xiaofeng Yang, Dylan England, Richard A Klinghoffer, Steven P Langston, Katherine Galvin, Gary Shapiro, Sai M Pulukuri, Serge Y Fuchs, Dennis Huszar
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models. Science translational medicine 13 (611) (2021)
Snahlata Singh, Sushil Kumar, Ratnesh Kumar Srivastava, Ajeya Nandi, Gatha Thacker, Hemma Murali, Sabrina Kim, Mary Baldeon, John Tobias, Mario Andres Blanco, Rizwan Saffie, M Raza Zaidi, Satrajit Sinha, Luca Busino, Serge Y Fuchs, Rumela Chakrabarti
Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling. Nature cell biology 22 (5) (2020)
Jeremy Ardanuy, Karen M Scanlon, Ciaran Skerry, Serge Y Fuchs, Nicholas H Carbonetti
Age-Dependent Effects of Type I and Type III IFNs in the Pathogenesis of Bordetella pertussis Infection and Disease. Journal of immunology (Baltimore, Md. : 1950) 204 (8) (2020)
Christina Cho, Riddhita Mukherjee, Amy R Peck, Yunguang Sun, Noreen McBrearty, Kanstantsin V Katlinski, Jun Gui, Priya K Govindaraju, Ellen Puré, Hallgeir Rui, Serge Y Fuchs
Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis. Oncogene 39 (38) (2020)