Eric T Kool

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 69

Top Topics

Pseudomonas Aeruginosa

Top Venues

Angewandte Chemie (International ed. in English)

Journal of the American Chemical Society

ACS chemical biology

Bioconjugate chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Bhoomika Pandit, Linglan Fang, Eric T Kool, Maksim Royzen
Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity. ACS chemical biology 19 (8) (2024)
Bhoomika Pandit, Linglan Fang, Eric T Kool, Maksim Royzen
Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity. ACS chemical biology 19 (8) (2024)
Junsong Guo, Siqin Chen, Yoshiyuki Onishi, Qi Shi, Yangyang Song, Hui Mei, Leilei Chen, Eric T Kool, Ru-Yi Zhu
RNA Control via Redox-Responsive Acylation. Angewandte Chemie (International ed. in English) (2024)
Ryuta Shioi, Sayantan Chatterjee, Lu Xiao, Wenrui Zhong, Eric T Kool
Second-Generation Chiral Amino Acid Derivatives Afford High Stereoselectivity and Stability in Aqueous RNA Acylation. The Journal of organic chemistry (2024)
Sayantan Chatterjee, Lu Xiao, Wenrui Zhong, Sheng Feng, Eric T Kool
Selective Arylation of RNA 2'-OH Groups via S N Ar Reaction with Trialkylammonium Heterocycles. Angewandte Chemie (International ed. in English) (2024)
Shijun Gao, Yuki Tahara, Eric T Kool, Marc M Greenberg
Promoter dependent RNA polymerase II bypass of the epimerizable DNA lesion, Fapy•dG and 8-Oxo-2'-deoxyguanosine. Nucleic acids research (2024)
Bhoomika Pandit, Linglan Fang, Eric T Kool, Maksim Royzen
Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity. ACS chemical biology (2024)
Shijun Gao, Yuki Tahara, Eric T Kool, Marc M Greenberg
Promoter dependent RNA polymerase II bypass of the epimerizable DNA lesion, Fapy•dG and 8-Oxo-2'-deoxyguanosine. Nucleic acids research 52 (13) (2024)
Ryuta Shioi, Sayantan Chatterjee, Lu Xiao, Wenrui Zhong, Eric T Kool
Second-Generation Chiral Amino Acid Derivatives Afford High Stereoselectivity and Stability in Aqueous RNA Acylation. The Journal of organic chemistry 89 (11) (2024)
Sayantan Chatterjee, Lu Xiao, Wenrui Zhong, Sheng Feng, Eric T Kool
Selective Arylation of RNA 2'-OH Groups via S N Ar Reaction with Trialkylammonium Heterocycles. Angewandte Chemie (International ed. in English) 63 (25) (2024)
Junsong Guo, Siqin Chen, Yoshiyuki Onishi, Qi Shi, Yangyang Song, Hui Mei, Leilei Chen, Eric T Kool, Ru-Yi Zhu
RNA Control via Redox-Responsive Acylation. Angewandte Chemie (International ed. in English) 63 (21) (2024)
Junsong Guo, Siqin Chen, Yoshiyuki Onishi, Qi Shi, Yangyang Song, Hui Mei, Leilei Chen, Eric T Kool, Ru-Yi Zhu
RNA Control via Redox-Responsive Acylation. Angewandte Chemie (International ed. in English) 63 (21) (2024)
Shijun Gao, Yuki Tahara, Eric T Kool, Marc M Greenberg
Promoter dependent RNA polymerase II bypass of the epimerizable DNA lesion, Fapy•dG and 8-Oxo-2'-deoxyguanosine. Nucleic acids research 52 (13) (2024)
Ryuta Shioi, Eric T Kool
Chemical diversity of reagents that modify RNA 2'-OH in water: a review. Chemical science (2024)
Bhoomika Pandit, Linglan Fang, Eric T Kool, Maksim Royzen
Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity. ACS chemical biology 19 (8) (2024)
Sayantan Chatterjee, Lu Xiao, Wenrui Zhong, Sheng Feng, Eric T Kool
Selective Arylation of RNA 2'-OH Groups via S N Ar Reaction with Trialkylammonium Heterocycles. Angewandte Chemie (International ed. in English) 63 (25) (2024)
Shijun Gao, Yuki Tahara, Eric T Kool, Marc M Greenberg
Promoter dependent RNA polymerase II bypass of the epimerizable DNA lesion, Fapy•dG and 8-Oxo-2'-deoxyguanosine. Nucleic acids research 52 (13) (2024)
Bhoomika Pandit, Linglan Fang, Eric T Kool, Maksim Royzen
Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity. ACS chemical biology (2024)
Ryuta Shioi, Lu Xiao, Eric T Kool
Aqueous Activation of RNA 2'-OH for Conjugation with Amines and Thiols. Bioconjugate chemistry 35 (1) (2023)
Linglan Fang, Lu Xiao, Yong Woong Jun, Yoshiyuki Onishi, Eric T Kool
Reversible 2'-OH acylation enhances RNA stability. Nature chemistry (2023)
Linglan Fang, Willem A Velema, Yujeong Lee, Lu Xiao, Michael G Mohsen, Anna M Kietrys, Eric T Kool
Pervasive transcriptome interactions of protein-targeted drugs. Nature chemistry (2023)
Ryuta Shioi, Lu Xiao, Linglan Fang, Eric T Kool
Efficient post-synthesis incorporation and conjugation of reactive ketones in RNA via 2'-acylation. Chemical communications (Cambridge, England) (2023)
Ryuta Shioi, Lu Xiao, Eric T Kool
Aqueous Activation of RNA 2'-OH for Conjugation with Amines and Thiols. Bioconjugate chemistry 35 (1) (2023)
Sayantan Chatterjee, Ryuta Shioi, Eric T Kool
Sulfonylation of RNA 2'-OH groups. ACS central science 9 (3) (2023)
Ryuta Shioi, Lu Xiao, Sayantan Chatterjee, Eric T Kool
Stereoselective RNA reaction with chiral 2'-OH acylating agents. Chemical science 14 (45) (2023)
Ryuta Shioi, Lu Xiao, Eric T Kool
Aqueous Activation of RNA 2'-OH for Conjugation with Amines and Thiols. Bioconjugate chemistry (2023)
Lu Xiao, Linglan Fang, Eric T Kool
RNA Infrastructure Profiling Illuminates Transcriptome Structure in Crowded Spaces. bioRxiv : the preprint server for biology (2023)
Sayantan Chatterjee, Ryuta Shioi, Eric T Kool
Sulfonylation of RNA 2'-OH groups. ACS central science 9 (3) (2023)
Ryuta Shioi, Lu Xiao, Eric T Kool
Aqueous Activation of RNA 2'-OH for Conjugation with Amines and Thiols. Bioconjugate chemistry 35 (1) (2023)
Yong Woong Jun, Melis Kant, Erdem Coskun, Takamitsu A Kato, Pawel Jaruga, Elizabeth Palafox, Miral Dizdaroglu, Eric T Kool
Possible Genetic Risks from Heat-Damaged DNA in Food. ACS central science 9 (6) (2023)
Sergio M Marques, Michaela Slanska, Klaudia Chmelova, Radka Chaloupkova, Martin Marek, Spencer Clark, Jiří Damborský, Eric T Kool, David Bednar, Zbynek Prokop
Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling. JACS Au 2 (6) (2022)
Lu Xiao, Linglan Fang, Sayantan Chatterjee, Eric T Kool
Diverse Reagent Scaffolds Provide Differential Selectivity of 2'-OH Acylation in RNA. Journal of the American Chemical Society 145 (1) (2022)
Lu Xiao, Linglan Fang, Sayantan Chatterjee, Eric T Kool
Diverse Reagent Scaffolds Provide Differential Selectivity of 2'-OH Acylation in RNA. Journal of the American Chemical Society (2022)
Yujeong Lee, Yoshiyuki Onishi, Lisa McPherson, Anna M Kietrys, Marian Hebenbrock, Yong Woong Jun, Ishani Das, Shanthi Adimoolam, Debin Ji, Michael G Mohsen, James M Ford, Eric T Kool
Enhancing Repair of Oxidative DNA Damage with Small-Molecule Activators of MTH1. ACS chemical biology 17 (8) (2022)
Yong Woong Jun, Eric T Kool
Chemical Tools for the Study of DNA Repair. Accounts of chemical research 55 (23) (2022)
Yong Woong Jun, Emily M Harcourt, Lu Xiao, David L Wilson, Eric T Kool
Efficient DNA fluorescence labeling via base excision trapping. Nature communications 13 (1) (2022)
Lu Xiao, Linglan Fang, Sayantan Chatterjee, Eric T Kool
Diverse Reagent Scaffolds Provide Differential Selectivity of 2'-OH Acylation in RNA. Journal of the American Chemical Society 145 (1) (2022)
Biswarup Jash, Eric T Kool
Conjugation of RNA via 2'-OH acylation: Mechanisms determining nucleotide reactivity. Chemical communications (Cambridge, England) 58 (22) (2022)
Lu Xiao, Linglan Fang, Sayantan Chatterjee, Eric T Kool
Diverse Reagent Scaffolds Provide Differential Selectivity of 2'-OH Acylation in RNA. Journal of the American Chemical Society 145 (1) (2022)
Lu Xiao, Yong Woong Jun, Eric T Kool
DNA Tiling Enables Precise Acylation-Based Labeling and Control of mRNA. Angewandte Chemie (International ed. in English) 60 (51) (2021)
Hyun Shin Park, Biswarup Jash, Lu Xiao, Yong Woong Jun, Eric T Kool
Control of RNA with quinone methide reversible acylating reagents. Organic & biomolecular chemistry 19 (38) (2021)
Melis Kant, Yu-Ki Tahara, Pawel Jaruga, Erdem Coskun, R Stephen Lloyd, Eric T Kool, Miral Dizdaroglu
Inhibition by Tetrahydroquinoline Sulfonamide Derivatives of the Activity of Human 8-Oxoguanine DNA Glycosylase (OGG1) for Several Products of Oxidatively induced DNA Base Lesions. ACS chemical biology 16 (1) (2020)
Lu Xiao, Maryam Habibian, Eric T Kool
Site-Selective RNA Functionalization via DNA-Induced Structure. Journal of the American Chemical Society 142 (38) (2020)
Willem A Velema, Hyun Shin Park, Anastasia Kadina, Lucian Orbai, Eric T Kool
Trapping Transient RNA Complexes by Chemically Reversible Acylation. Angewandte Chemie (International ed. in English) 59 (49) (2020)
Shugang Qin, Ping Lin, Qun Wu, Qinqin Pu, Chuanmin Zhou, Biao Wang, Pan Gao, Zhihan Wang, Ashley Gao, Madison Overby, Jinliang Yang, Jianxin Jiang, David L Wilson, Yu-Ki Tahara, Eric T Kool, Zhenwei Xia, Mingshan Jiang
Small-Molecule Inhibitor of 8-Oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during Pseudomonas aeruginosa Infection. Journal of immunology (Baltimore, Md. : 1950) 205 (8) (2020)
Yong Woong Jun, David L Wilson, Anna M Kietrys, Elizabeth R Lotsof, Savannah G Conlon, Sheila S David, Eric T Kool
An Excimer Clamp for Measuring Damaged-Base Excision by the DNA Repair Enzyme NTH1. Angewandte Chemie (International ed. in English) 59 (19) (2020)
Willem A Velema, Eric T Kool
The chemistry and applications of RNA 2'-OH acylation. Nature reviews. Chemistry 4 (1) (2019)
Maryam Habibian, Colin McKinlay, Timothy R Blake, Anna M Kietrys, Robert M Waymouth, Paul A Wender, Eric T Kool
Reversible RNA acylation for control of CRISPR-Cas9 gene editing. Chemical science 11 (4) (2019)
Lei Sun, Furqan M Fazal, Pan Li, James P Broughton, Byron Lee, Lei Tang, Wenze Huang, Eric T Kool, Howard Y Chang, Qiangfeng Cliff Zhang
RNA structure maps across mammalian cellular compartments. Nature structural & molecular biology 26 (4) (2019)
David L Wilson, Eric T Kool
Ultrafast Oxime Formation Enables Efficient Fluorescence Light-up Measurement of DNA Base Excision. Journal of the American Chemical Society 141 (49) (2019)
Yu-Ki Tahara, Anna M Kietrys, Marian Hebenbrock, Yujeong Lee, David L Wilson, Eric T Kool
Dual Inhibitors of 8-Oxoguanine Surveillance by OGG1 and NUDT1. ACS chemical biology 14 (12) (2019)
Michael G Mohsen, Debin Ji, Eric T Kool
Polymerase-amplified release of ATP (POLARA) for detecting single nucleotide variants in RNA and DNA. Chemical science 10 (11) (2019)
Maryam Habibian, Willem A Velema, Anna M Kietrys, Yoshiyuki Onishi, Eric T Kool
Polyacetate and Polycarbonate RNA: Acylating Reagents and Properties. Organic letters 21 (14) (2019)
Yu-Ki Tahara, Douglas Auld, Debin Ji, Andrew A Beharry, Anna M Kietrys, David L Wilson, Marta Jimenez, Daniel King, Zachary Nguyen, Eric T Kool
Potent and Selective Inhibitors of 8-Oxoguanine DNA Glycosylase. Journal of the American Chemical Society 140 (6) (2018)
Debin Ji, Anna M Kietrys, Yujeong Lee, Eric T Kool
ATP-Linked Chimeric Nucleotide as a Specific Luminescence Reporter of Deoxyuridine Triphosphatase. Bioconjugate chemistry 29 (5) (2018)
Willem A Velema, Anna M Kietrys, Eric T Kool
RNA Control by Photoreversible Acylation. Journal of the American Chemical Society 140 (10) (2018)
Dennis Larsen, Anna M Kietrys, Spencer A Clark, Hyun Shin Park, Andreas Ekebergh, Eric T Kool
Exceptionally rapid oxime and hydrazone formation promoted by catalytic amine buffers with low toxicity. Chemical science 9 (23) (2018)
Anastasia Kadina, Anna M Kietrys, Eric T Kool
RNA Cloaking by Reversible Acylation. Angewandte Chemie (International ed. in English) 57 (12) (2018)
Willem A Velema, Eric T Kool
Water-Soluble Leaving Group Enables Hydrophobic Functionalization of RNA. Organic letters 20 (20) (2018)
David L Wilson, Andrew A Beharry, Avinash Srivastava, Timothy R O'Connor, Eric T Kool
Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses. Angewandte Chemie (International ed. in English) 57 (39) (2018)
Vijay Singh, Shenliang Wang, Ke Min Chan, Spencer A Clark, Eric T Kool
Correction to "Genetically Encoded Multispectral Labeling of Proteins with Polyfluorophores on a DNA Backbone". Journal of the American Chemical Society 139 (5) (2017)
Ke Min Chan, Wang Xu, Hyukin Kwon, Anna M Kietrys, Eric T Kool
Luminescent Carbon Dot Mimics Assembled on DNA. Journal of the American Chemical Society 139 (37) (2017)
Wang Xu, Ke Min Chan, Eric T Kool
Fluorescent nucleobases as tools for studying DNA and RNA. Nature chemistry 9 (11) (2017)
Anna M Kietrys, Willem A Velema, Eric T Kool
Fingerprints of Modified RNA Bases from Deep Sequencing Profiles. Journal of the American Chemical Society 139 (47) (2017)
Willem A Velema, Eric T Kool
Fluorogenic Templated Reaction Cascades for RNA Detection. Journal of the American Chemical Society 139 (15) (2017)
Ke Min Chan, Dominik K Kölmel, Shenliang Wang, Eric T Kool
Color-Change Photoswitching of an Alkynylpyrene Excimer Dye. Angewandte Chemie (International ed. in English) 56 (23) (2017)
Dominik K Kölmel, Eric T Kool
Oximes and Hydrazones in Bioconjugation: Mechanism and Catalysis. Chemical reviews 117 (15) (2017)
David L Wilson, Eric T Kool
Fluorescent Probes of DNA Repair. ACS chemical biology 13 (7) (2017)
Spencer A Clark, Vijay Singh, Daniel Vega Mendoza, William Margolin, Eric T Kool
Light-Up "Channel Dyes" for Haloalkane-Based Protein Labeling in Vitro and in Bacterial Cells. Bioconjugate chemistry 27 (12) (2016)