Martin Marek

Scopus Author ID ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 13

Top Topics

Highly Efficient

Molecular Dynamics Simulations

Protein Protein

Structure Activity Relationship

Top Venues

Journal of medicinal chemistry

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Michal Nemergut, Daniel Pluskal, Jana Horackova, Tereza Sustrova, Jan Tulis, Tomas Barta, Racha Baatallah, Glwadys Gagnot, Veronika Novakova, Marika Majerova, Karolina Sedlackova, Sergio M Marques, Martin Toul, Jiří Damborský, Zbynek Prokop, David Bednář, Yves L Janin, Martin Marek
Illuminating the mechanism and allosteric behavior of NanoLuc luciferase. Nature communications 14 (1) (2023)
Klaudia Chmelova, Tadeja Gao, Martin Polak, Andrea Schenkmayerova, Tristan I Croll, Tanvir R Shaikh, Jana Skarupova, Radka Chaloupkova, Kay Diederichs, Randy J Read, Jiri Damborsky, Jiri Novacek, Martin Marek
Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and X-ray crystallography. Protein science : a publication of the Protein Society (2023)
Michal Nemergut, Sérgio M Marques, Lukas Uhrik, Tereza Vanova, Marketa Nezvedova, Darshak Chandulal Gadara, Durga Jha, Jan Tulis, Veronika Novakova, Joan Planas-Iglesias, Antonin Kunka, Anthony Legrand, Hana Hribkova, Veronika Pospisilova, Jiri Sedmik, Jan Raska, Zbynek Prokop, Jiri Damborsky, Dasa Bohaciakova, Zdenek Spacil, Lenka Hernychova, David Bednar, Martin Marek
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. Molecular neurodegeneration 18 (1) (2023)
Antonin Kunka, Sergio M Marques, Martin Havlasek, Michal Vasina, Nikola Velatova, Lucia Cengelova, David Kovář, Jiří Damborský, Martin Marek, David Bednar, Zbynek Prokop
Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning. ACS catalysis 13 (19) (2023)
Martin Toul, Jan Mican, Veronika Slonkova, Dmitri Nikitin, Martin Marek, David Bednář, Jiří Damborský, Zbynek Prokop
Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase. Stroke 53 (10) (2022)
Sergio M Marques, Michaela Slanska, Klaudia Chmelova, Radka Chaloupkova, Martin Marek, Spencer Clark, Jiří Damborský, Eric T Kool, David Bednar, Zbynek Prokop
Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling. JACS Au 2 (6) (2022)
Andrea Schenkmayerova, Gaspar P Pinto, Martin Toul, Martin Marek, Lenka Hernychova, Joan Planas-Iglesias, Veronika Daniel Liskova, Daniel Pluskal, Michal Vasina, Stephane Emond, Mark Dörr, Radka Chaloupkova, David Bednar, Zbynek Prokop, Florian Hollfelder, Uwe T Bornscheuer, Jiří Damborský
Engineering the protein dynamics of an ancestral luciferase. Nature communications 12 (1) (2021)
Klara Markova, Klaudia Chmelova, Sérgio M Marques, Philippe Carpentier, David Bednar, Jiří Damborský, Martin Marek
Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst. Chemical science 11 (41) (2020)
Matthes Zessin, Zsófia Kutil, Marat Meleshin, Zora Novakova, Ehab Ghazy, Diana Kalbas, Martin Marek, Christophe Romier, Wolfgang Sippl, Cyril Barinka, Mike Schutkowski
One-Atom Substitution Enables Direct and Continuous Monitoring of Histone Deacylase Activity. Biochemistry 58 (48) (2019)
Katharina Vögerl, Nghia Ong, Johanna Senger, Daniel Herp, Karin Schmidtkunz, Martin Marek, Martin Müller, Karin Bartel, Tajith Baba Shaik, Nicholas J Porter, Dina Robaa, David W Christianson, Christophe Romier, Wolfgang Sippl, Manfred Jung, Franz Bracher
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors. Journal of medicinal chemistry 62 (3) (2019)
Daria Monaldi, Dante Rotili, Julien Lancelot, Martin Marek, Nathalie Wössner, Alessia Lucidi, Daniela Tomaselli, Elizabeth Ramos-Morales, Christophe Romier, Raymond J Pierce, Antonello Mai, Manfred Jung
Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma mansoni (SmSirt2). Journal of medicinal chemistry 62 (19) (2019)
Martin Marek, Tajith B Shaik, Tino Heimburg, Alokta Chakrabarti, Julien Lancelot, Elizabeth Ramos-Morales, Cyrielle Da Veiga, Dmitrii Kalinin, Jelena Melesina, Dina Robaa, Karin Schmidtkunz, Takayoshi Suzuki, Ralph Holl, Eric Ennifar, Raymond J Pierce, Manfred Jung, Wolfgang Sippl, Christophe Romier
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. Journal of medicinal chemistry 61 (22) (2018)
Conrad V Simoben, Dina Robaa, Alokta Chakrabarti, Karin Schmidtkunz, Martin Marek, Julien Lancelot, Srinivasaraghavan Kannan, Jelena Melesina, Tajith Baba Shaik, Raymond J Pierce, Christophe Romier, Manfred Jung, Wolfgang Sippl
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing. Molecules (Basel, Switzerland) 23 (3) (2018)