Fabio Broccatelli

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 10

Top Topics

Molecular Dynamics Simulations

Structural Basis

Top Venues

ACS medicinal chemistry letters

Drug metabolism and disposition: the biological fate of chemicals

Molecular pharmaceutics

Expert opinion on drug discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Dahlia R Weiss, Javier L Baylon, Ethan D Evans, Anthony Paiva, Gerry Everlof, Jingfang Cutrone, Fabio Broccatelli
Balanced Permeability Index: A Multiparameter Index for Improved In Vitro Permeability. ACS medicinal chemistry letters 15 (4) (2024)
Dahlia R Weiss, Javier L Baylon, Ethan D Evans, Anthony Paiva, Gerry Everlof, Jingfang Cutrone, Fabio Broccatelli
Balanced Permeability Index: A Multiparameter Index for Improved In Vitro Permeability. ACS medicinal chemistry letters 15 (4) (2024)
Dahlia R Weiss, Javier L Baylon, Ethan D Evans, Anthony Paiva, Gerry Everlof, Jingfang Cutrone, Fabio Broccatelli
Balanced Permeability Index: A Multiparameter Index for Improved In Vitro Permeability. ACS medicinal chemistry letters 15 (4) (2024)
Fabio Broccatelli, Vijayabhaskar Veeravalli, Daniel Cashion, Javier L Baylon, Franco Lombardo, Lei Jia
Application of Mechanistic Multiparameter Optimization and Large-Scale In Vitro to In Vivo Pharmacokinetics Correlations to Small-Molecule Therapeutic Projects. Molecular pharmaceutics (2024)
Fabio Broccatelli, Vijayabhaskar Veeravalli, Daniel Cashion, Javier L Baylon, Franco Lombardo, Lei Jia
Application of Mechanistic Multiparameter Optimization and Large-Scale In Vitro to In Vivo Pharmacokinetics Correlations to Small-Molecule Therapeutic Projects. Molecular pharmaceutics 21 (9) (2024)
Robert S Jones, Christian Leung, Jae H Chang, Suzanne Brown, Ning Liu, Zhengyin Yan, Jane R Kenny, Fabio Broccatelli
Application of empirical scalars to enable early prediction of human hepatic clearance using IVIVE in drug discovery: an evaluation of 173 drugs. Drug metabolism and disposition: the biological fate of chemicals (2022)
Frederick Hsu, Yi-Chen Chen, Fabio Broccatelli
Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model. Drug metabolism and disposition: the biological fate of chemicals 49 (4) (2021)
Fabio Broccatelli, Cornelis E C A Hop, Matthew Wright
Strategies to optimize drug half-life in lead candidate identification. Expert opinion on drug discovery 14 (3) (2019)
Rosa Chan, Tom De Bruyn, Matthew Wright, Fabio Broccatelli
Comparing Mechanistic and Preclinical Predictions of Volume of Distribution on a Large Set of Drugs. Pharmaceutical research 35 (4) (2018)
Franco Lombardo, Prashant V Desai, Rieko Arimoto, Kelly E Desino, Holger Fischer, Christopher E Keefer, Carl Petersson, Susanne Winiwarter, Fabio Broccatelli
In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development. Journal of medicinal chemistry 60 (22) (2017)