Fen-Biao Gao

Publication Activity (10 Years)

Years Active: 2017-2022
Publications (10 Years): 11

Top Topics

Amyotrophic Lateral Sclerosis

Spectrum Disorder

Top Venues

Nature communications

Acta neuropathologica

The EMBO journal

Acta neuropathologica communications

This page only lists publications with an associated author ORCID identifier.

Publications

Yongping Chen, Gopinath Krishnan, Sepideh Parsi, Marine Pons, Veroniki Nikolaki, Lu Cao, Zuoshang Xu, Fen-Biao Gao
The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias. Acta neuropathologica communications 10 (1) (2022)
Anna B Loveland, Egor Svidritskiy, Denis Susorov, Soojin Lee, Alexander Park, Sarah Zvornicanin, Gabriel Demo, Fen-Biao Gao, Andrei A Korostelev
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nature communications 13 (1) (2022)
Dilara Halim, Fen-Biao Gao
RNA targets of TDP-43: Which one is more important in neurodegeneration? Translational neurodegeneration 11 (1) (2022)
Katharina E Meijboom, Abbas Abdallah, Nicholas P Fordham, Hiroko Nagase, Tomas C Rodriguez, Carolyn R Kraus, Tania F Gendron, Gopinath Krishnan, Rustam Esanov, Nadja S Andrade, Matthew J Rybin, Melina Ramic, Zachary D Stephens, Alireza Edraki, Meghan T Blackwood, Aydan Kahriman, Nils Henninger, Jean-Pierre A Kocher, Michael Benatar, Michael H Brodsky, Leonard Petrucelli, Fen-Biao Gao, Erik J Sontheimer, Robert H Brown, Zane Zeier, Christian Mueller
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro. Nature communications 13 (1) (2022)
Gopinath Krishnan, Denitza Raitcheva, Daniel Bartlett, Mercedes Prudencio, Diane M McKenna-Yasek, Catherine Douthwright, Björn E Oskarsson, Shafeeq Ladha, Oliver D King, Sami J Barmada, Timothy M Miller, Robert Bowser, Jonathan K Watts, Leonard Petrucelli, Robert H Brown, Mark W Kankel, Fen-Biao Gao
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD. Nature communications 13 (1) (2022)
Yubing Lu, Sandra Almeida, Fen-Biao Gao
TBK1 haploinsufficiency in ALS and FTD compromises membrane trafficking. Acta neuropathologica 142 (1) (2021)
Yoshifumi Sonobe, Jihad Aburas, Gopinath Krishnan, Andrew C Fleming, Ghanashyam Ghadge, Priota Islam, Eleanor C Warren, Yuanzheng Gu, Mark W Kankel, André E X Brown, Evangelos Kiskinis, Tania F Gendron, Fen-Biao Gao, Raymond P Roos, Paschalis Kratsios
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nature communications 12 (1) (2021)
Sandra Almeida, Gopinath Krishnan, Mia Rushe, Yuanzheng Gu, Mark W Kankel, Fen-Biao Gao
Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells. Acta neuropathologica 138 (6) (2019)
So Yoen Choi, Rodrigo Lopez-Gonzalez, Gopinath Krishnan, Hannah L Phillips, Alissa Nana Li, William W Seeley, Wei-Dong Yao, Sandra Almeida, Fen-Biao Gao
C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo. Nature neuroscience 22 (6) (2019)
Yeliz Yuva-Aydemir, Sandra Almeida, Gopinath Krishnan, Tania F Gendron, Fen-Biao Gao
Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD. Nature communications 10 (1) (2019)
Fen-Biao Gao, Sandra Almeida, Rodrigo Lopez-Gonzalez
Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder. The EMBO journal 36 (20) (2017)