Tania F Gendron

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 23

Top Topics

Amyotrophic Lateral Sclerosis

Transcranial Magnetic Stimulation

Top Venues

Science translational medicine

Molecular neurodegeneration

Science (New York, N.Y.)

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Katherine E Irwin, Udit Sheth, Philip C Wong, Tania F Gendron
Fluid biomarkers for amyotrophic lateral sclerosis: a review. Molecular neurodegeneration 19 (1) (2024)
Katherine E Irwin, Udit Sheth, Philip C Wong, Tania F Gendron
Fluid biomarkers for amyotrophic lateral sclerosis: a review. Molecular neurodegeneration 19 (1) (2024)
Katherine E Irwin, Udit Sheth, Philip C Wong, Tania F Gendron
Fluid biomarkers for amyotrophic lateral sclerosis: a review. Molecular neurodegeneration 19 (1) (2024)
Katherine E Irwin, Udit Sheth, Philip C Wong, Tania F Gendron
Fluid biomarkers for amyotrophic lateral sclerosis: a review. Molecular neurodegeneration 19 (1) (2024)
Katherine E Irwin, Udit Sheth, Philip C Wong, Tania F Gendron
Fluid biomarkers for amyotrophic lateral sclerosis: a review. Molecular neurodegeneration 19 (1) (2024)
Katherine E Irwin, Udit Sheth, Philip C Wong, Tania F Gendron
Fluid biomarkers for amyotrophic lateral sclerosis: a review. Molecular neurodegeneration 19 (1) (2024)
Rita Sattler, Bryan J Traynor, Janice Robertson, Ludo Van Den Bosch, Sami J Barmada, Clive N Svendsen, Matthew D Disney, Tania F Gendron, Philip C Wong, Matthew C Kiernan, Adam L Boxer, Suma Babu, Michael Benatar, Michael Kurnellas, Jonathan Daniel Rohrer, Christopher J Donnelly, Lynette M Bustos, Kendall Van Keuren-Jensen, Penny A Dacks, Marwan N Sabbagh, null null
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit. Neurology and therapy (2023)
Hsiao-Lin V Wang, Austin M Veire, Tania F Gendron, Marla Gearing, Jonathan D Glass, Peng Jin, Victor G Corces, Zachary T McEachin
Single nucleus multiome analysis of the prefrontal cortex from C9orf72 ALS/FTD patients illuminates pathways affected during disease progression. bioRxiv : the preprint server for biology (2023)
Hsiao-Lin V Wang, Austin M Veire, Tania F Gendron, Marla Gearing, Jonathan D Glass, Peng Jin, Victor G Corces, Zachary T McEachin
Single nucleus multiome analysis of the prefrontal cortex from C9orf72 ALS/FTD patients illuminates pathways affected during disease progression. bioRxiv : the preprint server for biology (2023)
Tania F Gendron, Leonard Petrucelli
Immunological drivers of amyotrophic lateral sclerosis. Science translational medicine 15 (721) (2023)
Wei Shao, Tiffany W Todd, Yanwei Wu, Caroline Y Jones, Jimei Tong, Karen R Jansen-West, Lillian M Daughrity, Jinyoung Park, Yuka Koike, Aishe Kurti, Mei Yue, Monica Castanedes Casey, Giulia Del Rosso, Judith A Dunmore, Desiree Zanetti Alepuz, Björn E Oskarsson, Gourisankar Ghosh, Casey N Cook, Mercedes Prudencio, Tania F Gendron, John D Fryer, Yong-Jie Zhang, Leonard Petrucelli
Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration. Science (New York, N.Y.) 378 (6615) (2022)
Junli Gao, Quinlan T Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N Coyne, Ritika Punathil, Bong Gu Kang, Morgan Dasovich, Austin M Veire, Mariely DeJesus Hernandez, Shuaichen Liu, Zheng Shi, Ruxandra Dafinca, Elise Fouquerel, Kevin Talbot, Tae-In Kam, Yong-Jie Zhang, Gourisankar Ghosh, Leonard Petrucelli, Marka van Blitterswijk, Lin Guo, Ted M Dawson, Valina L Dawson, Anthony K L Leung, Thomas E Lloyd, Tania F Gendron, Jeffrey D Rothstein, Ke Zhang
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins. Science translational medicine 14 (662) (2022)
Adam M Staffaroni, Melanie W Quintana, Barbara A Wendelberger, Hilary W Heuer, Lucy L Russell, Yann Cobigo, Amy Wolf, Sheng-Yang Matt Goh, Leonard Petrucelli, Tania F Gendron, Carolin Heller, Annie L Clark, Jack Carson Taylor, Amy Wise, Elise Ong, Leah Forsberg, Danielle Brushaber, Julio C Rojas, Lawren VandeVrede, Peter Ljubenkov, Joel Kramer, Kaitlin B Casaletto, Brian Appleby, Yvette Bordelon, Hugo Botha, Bradford C Dickerson, Kimiko Domoto-Reilly, Julie A Fields, Tatiana M Foroud, Ralitza Gavrilova, Daniel H Geschwind, Nupur Ghoshal, Jill Goldman, Jonathon Graff-Radford, Neill Graff-Radford, Murray Grossman, Matthew G H Hall, Ging-Yuek Robin Hsiung, Edward D Huey, David Irwin, David T Jones, Kejal Kantarci, Daniel Kaufer, David S Knopman, Walter Kremers, Argentina Lario Lago, Maria I Lapid, Irene Litvan, Diane Lucente, Ian R Mackenzie, Mario F Mendez, Carly Mester, Bruce L Miller, Chiadi U Onyike, Rosa Rademakers, Vijay K Ramanan, Eliana Marisa Ramos, Meghana Rao, Katya Rascovsky, Katherine P Rankin, Erik D Roberson, Rodolfo Savica, Maria Carmela Tartaglia, Sandra Weintraub, Bonnie Wong, David M Cash, Arabella Bouzigues, Imogen J Swift, Georgia Peakman, Martina Bocchetta, Emily G Todd, Rhian S Convery, James Benedict Rowe, Barbara Borroni, Daniela Galimberti, Pietro Tiraboschi, Mario Masellis, Elizabeth Finger, John C van Swieten, Harro Seelaar, Lize C Jiskoot, Sandro Sorbi, Chris R Butler, Caroline Graff, Alexander Gerhard, Tobias Langheinrich, Robert Jr Laforce, Raquel Sanchez-Valle, Alexandre de Mendonça, Fermin Moreno, Matthis Synofzik, Rik Vandenberghe, Simon Ducharme, Isabelle Le Ber, Johannes Levin, Adrian Danek, Markus Otto, Florence Pasquier, Isabel Santana, John Kornak, Bradley F Boeve, Howard J Rosen, Jonathan D Rohrer, Adam L Boxer, null null
Temporal order of clinical and biomarker changes in familial frontotemporal dementia. Nature medicine 28 (10) (2022)
Katharina E Meijboom, Abbas Abdallah, Nicholas P Fordham, Hiroko Nagase, Tomas C Rodriguez, Carolyn R Kraus, Tania F Gendron, Gopinath Krishnan, Rustam Esanov, Nadja S Andrade, Matthew J Rybin, Melina Ramic, Zachary D Stephens, Alireza Edraki, Meghan T Blackwood, Aydan Kahriman, Nils Henninger, Jean-Pierre A Kocher, Michael Benatar, Michael H Brodsky, Leonard Petrucelli, Fen-Biao Gao, Erik J Sontheimer, Robert H Brown, Zane Zeier, Christian Mueller
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro. Nature communications 13 (1) (2022)
Mercedes Prudencio, Young Erben, Christopher P Marquez, Karen R Jansen-West, Camila Franco-Mesa, Michael G Heckman, Launia J White, Judith A Dunmore, Casey N Cook, Meredith T Lilley, Yuping Song, Caroline F Harlow, Björn E Oskarsson, Katharine A Nicholson, Zbigniew K Wszolek, LaTonya J Hickson, John C O'Horo, Jonathan B Hoyne, Tania F Gendron, James F Meschia, Leonard Petrucelli
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19. Science translational medicine 13 (602) (2021)
Mercedes Prudencio, Hector Garcia-Moreno, Karen R Jansen-West, Rana Hanna Al-Shaikh, Tania F Gendron, Michael G Heckman, Matthew R Spiegel, Yari Carlomagno, Lillian M Daughrity, Yuping Song, Judith A Dunmore, Natalie Byron, Björn E Oskarsson, Katharine A Nicholson, Nathan P Staff, Sorina Gorcenco, Andreas Puschmann, João M Lemos, Cristina Januário, Mark S LeDoux, Joseph H Friedman, James Polke, Robin Labrum, Vikram G Shakkottai, Hayley S McLoughlin, Henry L Paulson, Takuya Konno, Osamu Onodera, Takeshi Ikeuchi, Mari Tada, Akiyoshi Kakita, John D Fryer, Christin Karremo, Inês Gomes, John N Caviness, Mark R Pittelkow, Jan O Aasly, Ronald F Pfeiffer, Venka Veerappan, Eric R Eggenberger, William David Freeman, Josephine F Huang, Ryan J Uitti, Klaas J Wierenga, Iris V Marin Collazo, Philip Wade Tipton, Jay A van Gerpen, Marka van Blitterswijk, Guojun Bu, Zbigniew K Wszolek, Paola Giunti, Leonard Petrucelli
Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. Science translational medicine 12 (566) (2021)
Tania F Gendron, Mohammed K Badi, Michael G Heckman, Karen R Jansen-West, George Koshy Vilanilam, Patrick W Johnson, Alexander R Burch, Ronald L Walton, Owen A Ross, Thomas G Brott, Timothy M Miller, James D Berry, Katharine A Nicholson, Zbigniew K Wszolek, Björn E Oskarsson, Kevin Navin Sheth, Lauren Hachmann Sansing, Guido J Falcone, Brett L Cucchiara, James F Meschia, Leonard Petrucelli
Plasma neurofilament light predicts mortality in patients with stroke. Science translational medicine 12 (569) (2021)
Jessica A Bush, Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M Meyer, Raphael I Benhamou, Jonathan L Chen, Tanya Khan, Sarah Wagner-Griffin, Montina J Van Meter, Yuquan Tong, Hailey Olafson, Kendra K McKee, Jessica L Childs-Disney, Tania F Gendron, Yong-Jie Zhang, Alyssa N Coyne, Eric T Wang, Ilyas Yildirim, Kye Won Wang, Leonard Petrucelli, Jeffrey D Rothstein, Matthew D Disney
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models. Science translational medicine 13 (617) (2021)
Yoshifumi Sonobe, Jihad Aburas, Gopinath Krishnan, Andrew C Fleming, Ghanashyam Ghadge, Priota Islam, Eleanor C Warren, Yuanzheng Gu, Mark W Kankel, André E X Brown, Evangelos Kiskinis, Tania F Gendron, Fen-Biao Gao, Raymond P Roos, Paschalis Kratsios
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nature communications 12 (1) (2021)
Casey N Cook, Yanwei Wu, Hana M Odeh, Tania F Gendron, Karen R Jansen-West, Giulia Del Rosso, Mei Yue, Peizhou Jiang, Edward Gomes, Jimei Tong, Lillian M Daughrity, Nicole M Avendano, Monica Castanedes Casey, Wei Shao, Björn E Oskarsson, Giulio S Tomassy, Alexander McCampbell, Frank Rigo, Gourisankar Ghosh, James Shorter, Yong-Jie Zhang, Leonard Petrucelli
C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy. Science translational medicine 12 (559) (2021)
Qiang Zhu, Jie Jiang, Tania F Gendron, Melissa McAlonis-Downes, Lulin Jiang, Amy Taylor, Sandra Diaz Garcia, Somasish Ghosh Dastidar, Maria J Rodriguez, Patrick King, Yongjie Zhang, Albert R La Spada, Huaxi Xu, Leonard Petrucelli, John Ravits, Sandrine Da Cruz, Clotilde Lagier-Tourenne, Don W Cleveland
Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72. Nature neuroscience 23 (5) (2020)
Shizuka B Yamada, Tania F Gendron, Teresa Niccoli, Naomi R Genuth, Rosslyn Grosely, Yingxiao Shi, Idoia Glaria, Nicholas J Kramer, Lisa Nakayama, Shirleen Fang, Tai J I Dinger, Annora Thoeng, Gabriel Rocha, Maria Barna, Joseph D Puglisi, Linda Partridge, Justin K Ichida, Adrian M Isaacs, Leonard Petrucelli, Aaron D Gitler
RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. Nature neuroscience 22 (9) (2019)
Yong-Jie Zhang, Lin Guo, Patrick K Gonzales, Tania F Gendron, Yanwei Wu, Karen Jansen-West, Aliesha D O'Raw, Sarah R Pickles, Mercedes Prudencio, Yari Carlomagno, Mariam A Gachechiladze, Connor Ludwig, Ruilin Tian, Jeannie Chew, Michael A DeTure, Wen-Lang Lin, Jimei Tong, Lillian M Daughrity, Mei Yue, Yuping Song, Jonathan W Andersen, Monica Castanedes Casey, Aishe Kurti, Abhishek Datta, Giovanna Antognetti, Alexander McCampbell, Rosa Rademakers, Björn E Oskarsson, Gourisankar Ghosh, Martin Edward Kampmann, Michael Emmerson Ward, John D Fryer, Christopher D Link, James Shorter, Leonard Petrucelli
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity. Science (New York, N.Y.) 363 (6428) (2019)