Focco van den Akker (F van den Akker)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 12

Top Venues

Protein science : a publication of the Protein Society

Antimicrobial agents and chemotherapy

PloS one

mBio

Case Western Reserve University

University of Washington (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Case Western Reserve University Jul 01 2003

United States

Associate Professor :: Biochemistry

Education History

University of Washington Aug 01 1993 - Jun 15 1997

United States

PHD :: Biochemistry

University of Wageningen Aug 15 1987 - Jun 15 1993

Netherlands

MSC

Publications

J Boorman, X Zeng, J Lin, Focco van den Akker
Structural insights into peptidoglycan glycosidase EtgA binding to the inner rod protein EscI of the type III secretion system via a designed EscI-EtgA fusion protein. Protein science : a publication of the Protein Society 33 (3) (2024)
J Boorman, X Zeng, J Lin, Focco van den Akker
Structural insights into peptidoglycan glycosidase EtgA binding to the inner rod protein EscI of the type III secretion system via a designed EscI-EtgA fusion protein. Protein science : a publication of the Protein Society 33 (3) (2024)
J Boorman, X Zeng, J Lin, Focco van den Akker
Structural insights into peptidoglycan glycosidase EtgA binding to the inner rod protein EscI of the type III secretion system via a designed EscI-EtgA fusion protein. Protein science : a publication of the Protein Society 33 (3) (2024)
T A Alsenani, S L Viviani, Krisztina M Papp-Wallace, Robert A Bonomo, Focco van den Akker
Exploring avibactam and relebactam inhibition of Klebsiella pneumoniae carbapenemase D179N variant: role of the Ω loop-held deacylation water. Antimicrobial agents and chemotherapy (2023)
Andrew R Mack, Vijay Kumar, Magdalena A Taracila, María Fernanda Mojica, Margaret O'Shea, William Schinabeck, Galen Silver, Andrea M Hujer, Krisztina M Papp-Wallace, Shuang Chen, Shozeb M Haider, Emilia Caselli, Fabio Prati, Focco van den Akker, Robert A Bonomo
Natural protein engineering in the Ω-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrobial agents and chemotherapy (2023)
Vijay Kumar, Jacob Boorman, William J Greenlee, Ximin Zeng, Jun Lin, Focco van den Akker
Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds. Protein science : a publication of the Protein Society (2023)
T A Alsenani, S L Viviani, Vijay Kumar, M A Taracila, C R Bethel, M D Barnes, Krisztina M Papp-Wallace, Ryan K Shields, M H Nguyen, C J Clancy, Robert A Bonomo, Focco van den Akker
Structural Characterization of the D179N and D179Y Variants of KPC-2 β-Lactamase: Ω-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam. Antimicrobial agents and chemotherapy 66 (4) (2022)
Michael G Hahn, Thomas Lampe, Sherif El Sheikh, Nils Griebenow, Elisabeth Woltering, Karl-Heinz Schlemmer, Lisa Dietz, Michael Gerisch, Frank Wunder, Eva-Maria Becker-Pelster, Thomas Mondritzki, Hanna Tinel, Andreas Knorr, Armin Kern, Dieter Lang, Joerg Hueser, Tibor Schomber, Agnes Benardeau, Frank Eitner, Hubert Truebel, Joachim Mittendorf, Vijay Kumar, Focco van den Akker, Martina Schaefer, Volker Geiss, Peter Sandner, Johannes-Peter Stasch
Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042). Journal of medicinal chemistry 64 (9) (2021)
Vijay Kumar, Snigdha A Mathure, Mijoon Lee, Jacob Boorman, Ximin Zeng, Jun Lin, Dusan Hesek, Elena Lastochkin, Shahriar Mobashery, Focco van den Akker
Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of Campylobacter jejuni. Biochemistry 60 (14) (2021)
Malligarjunan Rajavel, Vijay Kumar, Ha Nguyen, Jacob Wyatt, Steven H Marshall, Krisztina M Papp-Wallace, Prasad Deshpande, Satish Bhavsar, Ravindra Yeole, Sachin Bhagwat, Mahesh Patel, Robert A Bonomo, Focco van den Akker
Structural Characterization of Diazabicyclooctane β-Lactam "Enhancers" in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa. mBio 12 (1) (2021)
Vijay Kumar, Samantha L Viviani, Jeeda Ismail, Shreya Agarwal, Robert A Bonomo, Focco van den Akker
Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3. PloS one 16 (10) (2021)
Jagamya Vijayaraghavan, Vijay Kumar, Nikhil P Krishnan, Ross T Kaufhold, Ximin Zeng, Jun Lin, Focco van den Akker
Structural studies and molecular dynamics simulations suggest a processive mechanism of exolytic lytic transglycosylase from Campylobacter jejuni. PloS one 13 (5) (2018)

Focco van den Akker.css-eqlu8i{font-size:small;padding-left:4px;} (F van den Akker)

Publication Activity (10 Years)

Top Topics

Top Venues

Focco van den Akker (F van den Akker)