Gabriel Birkuš (Gabriel Birkus)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 13

Top Topics

Pseudomonas Aeruginosa

Molecular Docking

Cystic Fibrosis

Immune Response

Top Venues

Organic letters

Journal of medicinal chemistry

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Romain Amador, Jean-Jacques Vasseur, Gabriel Birkuš, Emmanuelle Bignon, Antonio Monari, Guillaume Clavé, Michael Smietana
Synthesis of Original Cyclic Dinucleotide Analogues Using the Sulfo-click Reaction. Organic letters 26 (4) (2024)
Romain Amador, Jean-Jacques Vasseur, Gabriel Birkuš, Emmanuelle Bignon, Antonio Monari, Guillaume Clavé, Michael Smietana
Synthesis of Original Cyclic Dinucleotide Analogues Using the Sulfo-click Reaction. Organic letters 26 (4) (2024)
Romain Amador, Jean-Jacques Vasseur, Gabriel Birkuš, Emmanuelle Bignon, Antonio Monari, Guillaume Clavé, Michael Smietana
Synthesis of Original Cyclic Dinucleotide Analogues Using the Sulfo-click Reaction. Organic letters (2024)
Romain Amador, Jean-Jacques Vasseur, Gabriel Birkuš, Emmanuelle Bignon, Antonio Monari, Guillaume Clavé, Michael Smietana
Synthesis of Original Cyclic Dinucleotide Analogues Using the Sulfo-click Reaction. Organic letters 26 (4) (2024)
Romain Amador, Jean-Jacques Vasseur, Gabriel Birkuš, Emmanuelle Bignon, Antonio Monari, Guillaume Clavé, Michael Smietana
Synthesis of Original Cyclic Dinucleotide Analogues Using the Sulfo-click Reaction. Organic letters 26 (4) (2024)
Marketa Pimkova Polidarova, Petra Brehova, Milan Dejmek, Gabriel Birkuš, Andrea Brazdova
STING Agonist-Mediated Cytokine Secretion Is Accompanied by Monocyte Apoptosis. ACS infectious diseases 8 (3) (2022)
Zdeněk Vavřina, Pavla Perlíková, Nemanja Milisavljević, Florian Chevrier, Miroslav Smola, Joshua Smith, Milan Dejmek, Vojtěch Havlíček, Miloš Buděšínský, Radek Liboska, Lenka Vanekova, Jiří Brynda, Evzen Boura, Pavlína Řezáčová, Michal Hocek, Gabriel Birkuš
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists. Journal of medicinal chemistry 65 (20) (2022)
Marketa Pimkova Polidarova, Lenka Vanekova, Petra Břehová, Milan Dejmek, Zdeněk Vavřina, Gabriel Birkuš, Andrea Brazdova
Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells. ACS infectious diseases (2022)
Miroslav Smola, Ondrej Gutten, Milan Dejmek, Milan Kožíšek, Thomas Evangelidis, Zahra Aliakbar Tehrani, Barbora Novotná, Radim Nencka, Gabriel Birkuš, Lubomír Rulíšek, Evzen Boura
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angewandte Chemie (International ed. in English) 60 (18) (2021)
Barbora Novotná, Lucie Holá, Monika Staś, Ondrej Gutten, Miroslav Smola, Martin Zavřel, Zdeněk Vavřina, Miloš Buděšínský, Radek Liboska, Florian Chevrier, Juraj Dobiaš, Evzen Boura, Lubomír Rulíšek, Gabriel Birkuš
Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. Biochemistry 60 (48) (2021)
Zdeněk Vavřina, Ondrej Gutten, Miroslav Smola, Martin Zavřel, Zahra Aliakbar Tehrani, Vilém Charvát, Milan Kožíšek, Evzen Boura, Gabriel Birkuš, Lubomír Rulíšek
Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory. Biochemistry 60 (8) (2021)
Markéta Pimková Polidarová, Petra Břehová, Martin Maxmilian Kaiser, Miroslav Smola, Martin Dračínský, Joshua Smith, Aleš Marek, Milan Dejmek, Michal Šála, Ondrej Gutten, Lubomír Rulíšek, Barbora Novotná, Andrea Brázdová, Zlatko Janeba, Radim Nencka, Evzen Boura, Ondřej Páv, Gabriel Birkuš
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP). Journal of medicinal chemistry 64 (11) (2021)
Barbora Novotná, Lenka Vaneková, Martin Zavřel, Miloš Buděšínský, Milan Dejmek, Miroslav Smola, Ondrej Gutten, Zahra Aliakbar Tehrani, Markéta Pimková Polidarová, Andrea Brázdová, Radek Liboska, Ivan Štěpánek, Zdeněk Vavřina, Tomáš Jandušík, Radim Nencka, Lubomír Rulíšek, Evžen Bouřa, Jiří Brynda, Ondřej Páv, Gabriel Birkuš
Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. Journal of medicinal chemistry 62 (23) (2019)