George Khelashvilli (George Khelashvili)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Topics

Molecular Dynamics Simulations

Structural Basis

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

ACS infectious diseases

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Juliana Debrito Carten, George Khelashvilli, Miya K Bidon, Marco R Straus, Tiffany Tang, Javier A Jaimes, Gary R Whittaker, Harel Weinstein, Susan Daniel
A Mechanistic Understanding of the Modes of Ca 2+ Ion Binding to the SARS-CoV-1 Fusion Peptide and Their Role in the Dynamics of Host Membrane Penetration. ACS infectious diseases 10 (2) (2024)
Juliana Debrito Carten, George Khelashvilli, Miya K Bidon, Marco R Straus, Tiffany Tang, Javier A Jaimes, Gary R Whittaker, Harel Weinstein, Susan Daniel
Mechanistic Understanding of the Modes of Ca 2+ Ion Binding to the SARS-CoV-1 Fusion Peptide and Their Role in the Dynamics of Host Membrane Penetration. ACS infectious diseases (2024)
Juliana Debrito Carten, George Khelashvilli, Miya K Bidon, Marco R Straus, Tiffany Tang, Javier A Jaimes, Gary R Whittaker, Harel Weinstein, Susan Daniel
A Mechanistic Understanding of the Modes of Ca 2+ Ion Binding to the SARS-CoV-1 Fusion Peptide and Their Role in the Dynamics of Host Membrane Penetration. ACS infectious diseases 10 (2) (2024)
Chiara D Mancinelli, Dagan C Marx, Alberto J Gonzalez-Hernandez, Kevin Huynh, Lucia Mancinelli, Anisul Arefin, George Khelashvilli, Joshua Levitz, David Eliezer
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains. Proceedings of the National Academy of Sciences of the United States of America 121 (29) (2024)
Chiara D Mancinelli, Dagan C Marx, Alberto J Gonzalez-Hernandez, Kevin Huynh, Lucia Mancinelli, Anisul Arefin, George Khelashvilli, Joshua Levitz, David Eliezer
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains. Proceedings of the National Academy of Sciences of the United States of America 121 (29) (2024)
Juliana Debrito Carten, George Khelashvilli, Miya K Bidon, Marco R Straus, Tiffany Tang, Javier A Jaimes, Gary R Whittaker, Harel Weinstein, Susan Daniel
A Mechanistic Understanding of the Modes of Ca 2+ Ion Binding to the SARS-CoV-1 Fusion Peptide and Their Role in the Dynamics of Host Membrane Penetration. ACS infectious diseases 10 (2) (2024)
Chiara D Mancinelli, Dagan C Marx, Alberto J Gonzalez-Hernandez, Kevin Huynh, Lucia Mancinelli, Anisul Arefin, George Khelashvilli, Joshua Levitz, David Eliezer
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains. Proceedings of the National Academy of Sciences of the United States of America 121 (29) (2024)
Chiara D Mancinelli, Dagan C Marx, Alberto J Gonzalez-Hernandez, Kevin Huynh, Lucia Mancinelli, Anisul Arefin, George Khelashvilli, Joshua Levitz, David Eliezer
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains. Proceedings of the National Academy of Sciences of the United States of America 121 (29) (2024)
Juliana Debrito Carten, George Khelashvilli, Miya K Bidon, Marco R Straus, Tiffany Tang, Javier A Jaimes, Gary R Whittaker, Harel Weinstein, Susan Daniel
A Mechanistic Understanding of the Modes of Ca 2+ Ion Binding to the SARS-CoV-1 Fusion Peptide and Their Role in the Dynamics of Host Membrane Penetration. ACS infectious diseases 10 (2) (2024)
Juliana Debrito Carten, George Khelashvilli, Miya K Bidon, Marco R Straus, Tiffany Tang, Javier A Jaimes, Gary R Whittaker, Harel Weinstein, Susan Daniel
A Mechanistic Understanding of the Modes of Ca 2+ Ion Binding to the SARS-CoV-1 Fusion Peptide and Their Role in the Dynamics of Host Membrane Penetration. ACS infectious diseases 10 (2) (2024)
Chiara D Mancinelli, Dagan C Marx, Alberto J Gonzalez-Hernandez, Lucia Mancinelli, George Khelashvilli, Joshua Levitz, David Eliezer
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains. bioRxiv : the preprint server for biology (2023)
Indu Menon, Taras Sych, Yeeun Son, Takefumi Morizumi, Joon Lee, Oliver P Ernst, George Khelashvilli, Erdinc Sezgin, Joshua Levitz, Anant K Menon
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors. bioRxiv : the preprint server for biology (2023)
Shana Bergman, Rosemary J Cater, Ambrose Plante, Filippo Mancia, George Khelashvilli
Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A. Nature communications 14 (1) (2023)
George Khelashvilli, Ekaterina Kots, Xiaolu Cheng, Michael V Levine, Harel Weinstein
The allosteric mechanism leading to an open-groove lipid conductive state of the TMEM16F scramblase. Communications biology 5 (1) (2022)
HengYi Xie, Ana V Rojas, Gia G Maisuradze, George Khelashvilli
Mechanistic Kinetic Model Reveals How Amyloidogenic Hydrophobic Patches Facilitate the Amyloid-β Fibril Elongation. ACS chemical neuroscience 13 (7) (2022)
George R Heath, Ekaterina Kots, Janice L Robertson, Shifra Lansky, George Khelashvilli, Harel Weinstein, Simon Scheuring
Localization atomic force microscopy. Nature 594 (7863) (2021)
Rana Ashkar, Milka Doktorova, Frederick A Heberle, Haden L Scott, Francisco N Barrera, John Katsaras, George Khelashvilli, Michael F Brown
Reply to Nagle et al.: The universal stiffening effects of cholesterol on lipid membranes. Proceedings of the National Academy of Sciences of the United States of America 118 (20) (2021)
Rosemary J Cater, Geok Lin Chua, Satchal K Erramilli, James E Keener, Brendon C Choy, Piotr Tokarz, Cheen Fei Chin, Debra Q Y Quek, Brian Kloss, Joseph G Pepe, Giacomo Parisi, Bernice H Wong, Oliver Biggs Clarke, Michael Thomas Marty, Anthony A Kossiakoff, George Khelashvilli, David L Silver, Filippo Mancia
Structural basis of omega-3 fatty acid transport across the blood-brain barrier. Nature 595 (7866) (2021)
Itay Schachter, Christoph Allolio, George Khelashvilli, Daniel Harries
Confinement in Nanodiscs Anisotropically Modifies Lipid Bilayer Elastic Properties. The journal of physical chemistry. B 124 (33) (2020)
Ismael Rodríguez-Espigares, Mariona Torrens-Fontanals, Johanna K S Tiemann, David Aranda-García, Juan Manuel Ramírez-Anguita, Tomasz Maciej Stepniewski, Nathalie Worp, Alejandro Varela-Rial, Adrián Morales-Pastor, Brian Medel-Lacruz, Gáspár Pándy-Szekeres, Eduardo Mayol, Toni Giorgino, Jens Carlsson, Xavier Deupi, Slawomir Filipek, Marta Filizola, José Carlos Gómez-Tamayo, Angel Gonzalez, Hugo Gutiérrez-de-Terán, Mireia Jiménez-Rosés, Willem Jespers, Jon Kapla, George Khelashvilli, Peter Kolb, Dorota Latek, Maria Marti-Solano, Pierre Matricon, Minos-Timotheos Matsoukas, Przemyslaw Miszta, Mireia Olivella, Laura Perez-Benito, Davide Provasi, Santiago Ríos, Iván R Torrecillas, Jessica Sallander, Agnieszka Sztyler, Silvana Vasile, Harel Weinstein, Ulrich Zachariae, Peter W Hildebrand, Gianni De Fabritiis, Ferran Sanz, David E Gloriam, Arnau Cordomi, Ramon Guixà-Gonzaléz, Jana Selent
GPCRmd uncovers the dynamics of the 3D-GPCRome. Nature methods 17 (8) (2020)
Saptarshi Chakraborty, Milka Doktorova, Trivikram R Molugu, Frederick A Heberle, Haden L Scott, Boris Dzikovski, Michihiro Nagao, Laura-Roxana Stingaciu, Robert F Standaert, Francisco N Barrera, John Katsaras, George Khelashvilli, Michael F Brown, Rana Ashkar
How cholesterol stiffens unsaturated lipid membranes. Proceedings of the National Academy of Sciences of the United States of America 117 (36) (2020)
Kamil Gotfryd, Thomas Boesen, Jonas S Mortensen, George Khelashvilli, Matthias Quick, Daniel S Terry, Julie Winkel Missel, Michael V LeVine, Pontus Emanuel Gourdon, Scott C Blanchard, Jonathan A Javitch, Harel Weinstein, Claus J Løland, Poul Nissen, Ulrik Gether
X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nature communications 11 (1) (2020)
George Khelashvilli, Neha Chauhan, Kalpana Pandey, David Eliezer, Anant K Menon
Exchange of water for sterol underlies sterol egress from a StARkin domain. eLife 8 (2019)
Ambrose Plante, Derek M Shore, Giulia Morra, George Khelashvilli, Harel Weinstein
A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs. Molecules (Basel, Switzerland) 24 (11) (2019)
George Khelashvilli, Maria E Falzone, Xiaolu Cheng, Byoung-Cheol Lee, Alessio Accardi, Harel Weinstein
Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca2+-bound nhTMEM16. Nature communications 10 (1) (2019)
Lindsay D Clark, Igor Dikiy, Karen Chapman, Karin Ej Rödström, James Aramini, Michael V LeVine, George Khelashvilli, Søren Gf Rasmussen, Kevin H Gardner, Daniel M Rosenbaum
Ligand modulation of sidechain dynamics in a wild-type human GPCR. eLife 6 (2017)