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Harel Weinstein

ORCID

Publication Activity (10 Years)

Years Active: 2014-2022
Publications (10 Years): 15

Top Venues

Nature communications

Molecules (Basel, Switzerland)

Proceedings of the National Academy of Sciences of the United States of America

ACS bio & med chem Au

Weill Cornell Medical College

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Weill Cornell Medical College Oct 2o 2002

United States

Professor and Chairman :: Physiology and Biophysics

Publications

Yaron Bram, Xiaohua Duan, Benjamin E Nilsson-Payant, Vasuretha Chandar, Hao Wu, Derek Shore, Alvaro Fajardo, Saloni Sinha, Nora Hassan, Harel Weinstein, Benjamin R TenOever, Shuibing Chen, Robert E Schwartz
Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path. ACS bio & med chem Au 2 (6) (2022)
George Khelashvilli, Ekaterina Kots, Xiaolu Cheng, Michael V Levine, Harel Weinstein
The allosteric mechanism leading to an open-groove lipid conductive state of the TMEM16F scramblase. Communications biology 5 (1) (2022)
James Osei-Owusu, Ekaterina Kots, Zheng Ruan, Ljubica Mihaljević, Kevin Hong Chen, Ami Tamhaney, Xinyu Ye, Wei Lü, Harel Weinstein, Zhaozhu Qiu
Molecular determinants of pH sensing in the proton-activated chloride channel. Proceedings of the National Academy of Sciences of the United States of America 119 (31) (2022)
Yaron Bram, Xiaohua Duan, Benjamin E Nilsson-Payant, Vasuretha Chandar, Hao Wu, Derek Shore, Alvaro Fajardo, Saloni Sinha, Nora Hassan, Harel Weinstein, Benjamin R TenOever, Shuibing Chen, Robert E Schwartz
Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path. ACS bio & med chem Au 2 (6) (2022)
George R Heath, Ekaterina Kots, Janice L Robertson, Shifra Lansky, George Khelashvilli, Harel Weinstein, Simon Scheuring
Localization atomic force microscopy. Nature 594 (7863) (2021)
Ambrose Plante, Harel Weinstein
Ligand-Dependent Conformational Transitions in Molecular Dynamics Trajectories of GPCRs Revealed by a New Machine Learning Rare Event Detection Protocol. Molecules (Basel, Switzerland) 26 (10) (2021)
Ekaterina Kots, Derek M Shore, Harel Weinstein
Simulation of pH-Dependent Conformational Transitions in Membrane Proteins: The CLC-ec1 Cl-/H+ Antiporter. Molecules (Basel, Switzerland) 26 (22) (2021)
Ismael Rodríguez-Espigares, Mariona Torrens-Fontanals, Johanna K S Tiemann, David Aranda-García, Juan Manuel Ramírez-Anguita, Tomasz Maciej Stepniewski, Nathalie Worp, Alejandro Varela-Rial, Adrián Morales-Pastor, Brian Medel-Lacruz, Gáspár Pándy-Szekeres, Eduardo Mayol, Toni Giorgino, Jens Carlsson, Xavier Deupi, Slawomir Filipek, Marta Filizola, José Carlos Gómez-Tamayo, Angel Gonzalez, Hugo Gutiérrez-de-Terán, Mireia Jiménez-Rosés, Willem Jespers, Jon Kapla, George Khelashvilli, Peter Kolb, Dorota Latek, Maria Marti-Solano, Pierre Matricon, Minos-Timotheos Matsoukas, Przemyslaw Miszta, Mireia Olivella, Laura Perez-Benito, Davide Provasi, Santiago Ríos, Iván R Torrecillas, Jessica Sallander, Agnieszka Sztyler, Silvana Vasile, Harel Weinstein, Ulrich Zachariae, Peter W Hildebrand, Gianni De Fabritiis, Ferran Sanz, David E Gloriam, Arnau Cordomi, Ramon Guixà-Gonzaléz, Jana Selent
GPCRmd uncovers the dynamics of the 3D-GPCRome. Nature methods 17 (8) (2020)
Kamil Gotfryd, Thomas Boesen, Jonas S Mortensen, George Khelashvilli, Matthias Quick, Daniel S Terry, Julie Winkel Missel, Michael V LeVine, Pontus Emanuel Gourdon, Scott C Blanchard, Jonathan A Javitch, Harel Weinstein, Claus J Løland, Poul Nissen, Ulrik Gether
X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nature communications 11 (1) (2020)
Ambrose Plante, Derek M Shore, Giulia Morra, George Khelashvilli, Harel Weinstein
A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs. Molecules (Basel, Switzerland) 24 (11) (2019)
George Khelashvilli, Maria E Falzone, Xiaolu Cheng, Byoung-Cheol Lee, Alessio Accardi, Harel Weinstein
Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca2+-bound nhTMEM16. Nature communications 10 (1) (2019)
Michael V LeVine, Daniel S Terry, George Khelashvili, Zarek S Siegel, Matthias Quick, Jonathan A Javitch, Scott C Blanchard, Harel Weinstein
The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor. Proceedings of the National Academy of Sciences of the United States of America 116 (32) (2019)
George Khelashvili, Xiaolu Cheng, Maria E Falzone, Milka Doktorova, Alessio Accardi, Harel Weinstein
Membrane lipids are both the substrates and a mechanistically responsive environment of TMEM16 scramblase proteins. Journal of computational chemistry 41 (6) (2019)
Asghar M Razavi, George Khelashvili, Harel Weinstein
How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties. BMC biology 16 (1) (2018)
Daniel S Terry, Rachel A Kolster, Matthias Quick, Michael V LeVine, George Khelashvili, Zhou Zhou, Harel Weinstein, Jonathan A Javitch, Scott C Blanchard
A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport. Nature communications 9 (1) (2018)
Kelli Kazmier, Shruti Sharma, Matthias Quick, Shahidul M Islam, Benoît Roux, Harel Weinstein, Jonathan A Javitch, Hassane S McHaourab
Conformational dynamics of ligand-dependent alternating access in LeuT. Nature structural & molecular biology 21 (5) (2014)

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Publication Activity (10 Years)

Top Topics

Top Venues

Harel Weinstein