David E Gloriam (D E Gloriam, David Gloriam)

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 37

Top Venues

Journal of medicinal chemistry

Nature

British journal of pharmacology

Nucleic acids research

University of Copenhagen

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Copenhagen Sep 01 2008

Denmark

Associate Professor :: Department of Drug Design and Pharmacology

Publications

David E Gloriam, Thor Thorsen, Yashraj Kulkarni, David A Sykes, Andreas Bøggild, Taner Drace, Pattarin Hompluem, Christos Iliopoulos-Tsoutsouvas, Spyros P Nikas, Henrik Daver, Alexandros Makriyannis, Poul Nissen, Michael Gajhede, Dmitry B Veprintsev, Thomas Boesen, Jette Kastrup
Structural basis of Δ9-THC analog activity at the Cannabinoid 1 receptor. Research square (2024)
David E Gloriam, Thor Thorsen, Yashraj Kulkarni, David A Sykes, Andreas Bøggild, Taner Drace, Pattarin Hompluem, Christos Iliopoulos-Tsoutsouvas, Spyros P Nikas, Henrik Daver, Alexandros Makriyannis, Poul Nissen, Michael Gajhede, Dmitry B Veprintsev, Thomas Boesen, Jette Kastrup
Structural basis of Δ 9 -THC analog activity at the Cannabinoid 1 receptor. Research square (2024)
David E Gloriam, Thor Thorsen, Yashraj Kulkarni, David A Sykes, Andreas Bøggild, Taner Drace, Pattarin Hompluem, Christos Iliopoulos-Tsoutsouvas, Spyros P Nikas, Henrik Daver, Alexandros Makriyannis, Poul Nissen, Michael Gajhede, Dmitry B Veprintsev, Thomas Boesen, Jette Kastrup
Structural basis of Δ9-THC analog activity at the Cannabinoid 1 receptor. Research square (2024)
David Reiner, Jakob Sture Madsen, David E Gloriam, Hans Bräuner-Osborne, Alexander S Hauser
Differential G protein activation by the long and short isoforms of the dopamine D 2 receptor. British journal of pharmacology (2024)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Eline Pottie, Christian B M Poulie, Icaro A Simon, Kasper Harpsøe, Laura D'Andrea, Igor V Komarov, David E Gloriam, Anders A Jensen, Jesper L Kristensen, Christophe Pol Stove
Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT 2A Receptor Agonists. ACS chemical neuroscience (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Lukas Grätz, Maria Kowalski-Jahn, Magdalena M Scharf, Pawel Kozielewicz, Michael Jahn, Julien Bous, Nevin A Lambert, David E Gloriam, Gunnar Schulte
Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations. Nature communications 14 (1) (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry (2023)
Gáspár Pándy-Szekeres, Luis P Taracena Herrera, Jimmy Caroli, Ali A Kermani, Yashraj Kulkarni, György M Keserű, David E Gloriam
GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface interactions. Nucleic acids research (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Jimmy Caroli, Alibek Mamyrbekov, Kasper Harpsøe, Sahar Gardizi, Linda Dörries, Eshan Ghosh, Alexander Sebastian Hauser, Albert Jelke Kooistra, David E Gloriam
A community Biased Signaling Atlas. Nature chemical biology (2023)
Christian R O Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K-Y Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M Jensen, Palash Jain, Mads M Nygaard, Kasper Harpsøe, David E Gloriam, Mehdi Mobli, Kristian Stro Mgaard
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of medicinal chemistry 66 (4) (2023)
Charlotte Avet, Arturo Mancini, Billy Breton, Christian Le Gouill, Alexander Sebastian Hauser, Claire Normand, Hiroyuki Kobayashi, Florence Gross, Mireille Hogue, Viktoriya Lukasheva, Stéphane St-Onge, Marilyn Carrier, Madeleine Héroux, Sandra Morissette, Eric B Fauman, Jean-Philippe Fortin, Stephan Schann, Xavier Leroy, David E Gloriam, Michel Bouvier
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs. eLife 11 (2022)
Christian B M Poulie, Eline Pottie, Icaro A Simon, Kasper Harpsøe, Laura D'Andrea, Igor V Komarov, David E Gloriam, Anders A Jensen, Christophe Pol Stove, Jesper L Kristensen
Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT 2A Receptor Agonists. Journal of medicinal chemistry 65 (18) (2022)
Manbir Sandhu, Aaron Cho, Ning Ma, Elizaveta Mukhaleva, Yoon Namkung, Sangbae Lee, Soumadwip Ghosh, John H Lee, David E Gloriam, Stéphane A Laporte, M Madan Babu, Nagarajan Vaidehi
Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity. Nature communications 13 (1) (2022)
Peter Kolb, Terry Kenakin, Stephen P H Alexander, Marcel Bermudez, Laura M Bohn, Christian S Breinholt, Michel Bouvier, Stephen J Hill, Evi Kostenis, Kirill A Martemyanov, Rick R Neubig, H Ongun Onaran, Sudarshan Rajagopal, Bryan L Roth, Jana Selent, Arun K Shukla, Martha E Sommer, David E Gloriam
Community guidelines for GPCR ligand bias: IUPHAR review 32. British journal of pharmacology 179 (14) (2022)
Gáspár Pándy-Szekeres, Jimmy Caroli, Alibek Mamyrbekov, Ali A Kermani, György M Keserű, Albert Jelke Kooistra, David E Gloriam
GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources. Nucleic acids research (2022)
Alexander Sebastian Hauser, Charlotte Avet, Claire Normand, Arturo Mancini, Asuka Inoue, Michel Bouvier, David E Gloriam
Common coupling map advances GPCR-G protein selectivity. eLife 11 (2022)
Albert Jelke Kooistra, Christian Munk, Alexander Sebastian Hauser, David E Gloriam
An online GPCR structure analysis platform. Nature structural & molecular biology 28 (11) (2021)
Alexander Sebastian Hauser, Albert Jelke Kooistra, Christian Munk, Franziska Marie Heydenreich, Dmitry B Veprintsev, Michel Bouvier, M Madan Babu, David E Gloriam
GPCR activation mechanisms across classes and macro/microscales. Nature structural & molecular biology 28 (11) (2021)
Frederik Rostrup, Christina B Falk-Petersen, Kasper Harpso E, Stine Buchleithner, Irene Conforti, Sascha Jung, David E Gloriam, Tanja Schirmeister, Petrine Wellendorph, Bente Frølund
Structural Determinants for the Mode of Action of Imidazopyridine DS2 at δ-Containing γ-Aminobutyric Acid Type A Receptors. Journal of medicinal chemistry 64 (8) (2021)
Chihiro Nakamoto, Yuhei Goto, Yoko Tomizawa, Yuko Fukata, Masaki Fukata, Kasper Harpsøe, David E Gloriam, Kazuhiro Aoki, Tomonori Takeuchi
A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro. Molecular brain 14 (1) (2021)
Yali Zhou, Henrik Daver, Boris Trapkov, Lijie Wu, Meng Wu, Kasper Harpsøe, Patrick R Gentry, Kaiwen Liu, Marina Larionova, Junlin Liu, Na Chen, Hans Bräuner-Osborne, David E Gloriam, Tian Hua, Zhi-Jie Liu
Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139. Cell research 32 (2) (2021)
Peiyu Xu, Sijie Huang, Huibing Zhang, Chunyou Mao, X Edward Zhou, Xi Cheng, Icaro A Simon, Dan-Dan Shen, Hsin-Yung Yen, Carol V Robinson, Kasper Harpsøe, Bo Svensson, Jia Guo, Hualiang Jiang, David E Gloriam, Karsten Melcher, Yi Jiang, Yan Zhang, H Eric Xu
Structural insights into the lipid and ligand regulation of serotonin receptors. Nature 592 (7854) (2021)
Gáspár Pándy-Szekeres, Mauricio Esguerra, Alexander S Hauser, Jimmy Caroli, Christian Munk, Steven Pilger, György M Keserű, Albert Jelke Kooistra, David E Gloriam
The G protein database, GproteinDb. Nucleic acids research (2021)
Ismael Rodríguez-Espigares, Mariona Torrens-Fontanals, Johanna K S Tiemann, David Aranda-García, Juan Manuel Ramírez-Anguita, Tomasz Maciej Stepniewski, Nathalie Worp, Alejandro Varela-Rial, Adrián Morales-Pastor, Brian Medel-Lacruz, Gáspár Pándy-Szekeres, Eduardo Mayol, Toni Giorgino, Jens Carlsson, Xavier Deupi, Slawomir Filipek, Marta Filizola, José Carlos Gómez-Tamayo, Angel Gonzalez, Hugo Gutiérrez-de-Terán, Mireia Jiménez-Rosés, Willem Jespers, Jon Kapla, George Khelashvilli, Peter Kolb, Dorota Latek, Maria Marti-Solano, Pierre Matricon, Minos-Timotheos Matsoukas, Przemyslaw Miszta, Mireia Olivella, Laura Perez-Benito, Davide Provasi, Santiago Ríos, Iván R Torrecillas, Jessica Sallander, Agnieszka Sztyler, Silvana Vasile, Harel Weinstein, Ulrich Zachariae, Peter W Hildebrand, Gianni De Fabritiis, Ferran Sanz, David E Gloriam, Arnau Cordomi, Ramon Guixà-Gonzaléz, Jana Selent
GPCRmd uncovers the dynamics of the 3D-GPCRome. Nature methods 17 (8) (2020)
Alexander Sebastian Hauser, David E Gloriam, Hans Bräuner-Osborne, Simon R Foster
Novel approaches leading towards peptide GPCR de-orphanisation. British journal of pharmacology 177 (5) (2020)
Maria Marti-Solano, Stephanie E Crilly, Duccio Malinverni, Christian Munk, Matthew Harris, Abigail Pearce, Tezz Quon, Amanda E Mackenzie, Xusheng Wang, Junmin Peng, Andrew B Tobin, Graham Ladds, Graeme Milligan, David E Gloriam, Manojkumar A Puthenveedu, M Madan Babu
Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature (2020)
Vaithish Velazhahan, Ning Ma, Gáspár Pándy-Szekeres, Albert J Kooistra, Yang Lee, David E Gloriam, Nagarajan Vaidehi, Christopher G Tate
Structure of the class D GPCR Ste2 dimer coupled to two G proteins. Nature 589 (7840) (2020)
Maria Marti-Solano, Stephanie E Crilly, Duccio Malinverni, Christian Munk, Matthew Harris, Abigail Pearce, Tezz Quon, Amanda E Mackenzie, Xusheng Wang, Junmin Peng, Andrew B Tobin, Graham Ladds, Graeme Milligan, David E Gloriam, Manojkumar A Puthenveedu, M Madan Babu
Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature 587 (7835) (2020)
Anne Cathrine Nøhr, Mohamed A Shehata, Daniel Palmer, Rina Pokhrel, Maria Vallianou, Simon R Foster, Patrick R Gentry, David E Gloriam, Hans Bräuner-Osborne
Identification of a novel scaffold for a small molecule GPR139 receptor agonist. Scientific reports 9 (1) (2019)
Christian Munk, Eshita Mutt, Vignir Isberg, Louise F Nikolajsen, Janne M Bibbe, Tilman Flock, Michael A Hanson, Raymond C Stevens, Xavier Deupi, David E Gloriam
An online resource for GPCR structure determination and analysis. Nature methods 16 (2) (2019)
Anne Cathrine Nøhr, Willem Jespers, Mohamed A Shehata, Leonard Floryan, Vignir Isberg, Kirsten Bayer Andersen, Johan Åqvist, Hugo Gutiérrez-de-Terán, Hans Bräuner-Osborne, David E Gloriam
The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site. Scientific reports 7 (1) (2017)
Ida Osborn Frandsen, Michael W Boesgaard, Kimberley Fidom, Alexander Sebastian Hauser, Vignir Isberg, Hans Bräuner-Osborne, Petrine Wellendorph, David E Gloriam
Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method. Scientific reports 7 (1) (2017)
C Munk, Vignir Isberg, S Mordalski, Kasper Harpsøe, K Rataj, Alexander Sebastian Hauser, Peter Kolb, A J Bojarski, G Vriend, David E Gloriam
GPCRdb: the G protein-coupled receptor database - an introduction. British journal of pharmacology 173 (14) (2016)
Xiao-Feng Xiong, Hang Zhang, Christina R Underwood, Kasper Harpsøe, Thomas J Gardella, Mie F Wöldike, Michael Mannstadt, David E Gloriam, Hans Bräuner-Osborne, Kristian Stro Mgaard
Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors. Nature chemistry 8 (11) (2016)

David E Gloriam.css-eqlu8i{font-size:small;padding-left:4px;} (D E Gloriam, David Gloriam)

Publication Activity (10 Years)

Top Topics

Top Venues

David E Gloriam (D E Gloriam, David Gloriam)