Marta Filizola

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 38

Top Venues

Nature structural & molecular biology

Science advances

Nature communications

The Journal of chemical physics

Icahn School of Medicine at Mount Sinai

II Universita' di Napoli (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Icahn School of Medicine at Mount Sinai

United States

Dean :: Graduate School of Biomedical Sciences

Icahn School of Medicine at Mount Sinai

United States

Professor :: Pharmacological Sciences

Icahn School of Medicine at Mount Sinai

United States

Associate Professor :: Structural and Chemical Biology

Icahn School of Medicine at Mount Sinai

United States

Assistant Professor :: Structural and Chemical Biology

Weill Medical College of Cornell University

United States

Assistant Professor :: Physiology & Biophysics

Weill Medical College of Cornell University

United States

Instructor :: Physiology & Biophysics

Icahn School of Medicine at Mount Sinai

United States

Instructor :: Physiology & Biophysics

Education History

II Universita' di Napoli

Italy

PHD

Università degli Studi di Napoli Federico II

Italy

MSC :: Chemistry

Università degli Studi di Napoli Federico II

Italy

BSC :: Chemistry

Publications

Alexa Strauss, Alberto J Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada, Melanie Kristt, Anisul Arefin, Kevin Huynh, Dagan C Marx, Kristen Gilliland, Bruce J Melancon, Marta Filizola, Joel R Meyerson, Joshua Levitz
Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization. Nature communications 15 (1) (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology 31 (4) (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology (2024)
Alexa Strauss, Alberto J Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada, Melanie Kristt, Anisul Arefin, Kevin Huynh, Dagan C Marx, Kristen Gilliland, Bruce J Melancon, Marta Filizola, Joel R Meyerson, Joshua Levitz
Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization. Nature communications 15 (1) (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology (2024)
Richard Quintana-Feliciano, Jithesh Kottur, Mi Ni, Rikhia Ghosh, Leslie Salas-Estrada, Goran Ahlsen, Olga Rechkoblit, Lawrence Shapiro, Marta Filizola, Gang Fang, Aneel K Aggarwal
Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation. Nature communications 15 (1) (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Author Correction: Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology (2024)
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R. Science advances 10 (16) (2024)
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R. Science advances 10 (16) (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology 31 (4) (2024)
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R. Science advances 10 (16) (2024)
Alexa Strauss, Alberto J Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada, Melanie Kristt, Anisul Arefin, Kevin Huynh, Dagan C Marx, Kristen Gilliland, Bruce J Melancon, Marta Filizola, Joel R Meyerson, Joshua Levitz
Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization. Nature communications 15 (1) (2024)
Daniel Wacker, Marta Filizola
Can Targeting the Sodium Site via Water Molecules Lead to the Development of Safer Opioids? ACS central science 10 (8) (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Author Correction: Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology 31 (4) (2024)
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R. Science advances 10 (16) (2024)
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R. Science advances 10 (16) (2024)
Daniel Wacker, Marta Filizola
Can Targeting the Sodium Site via Water Molecules Lead to the Development of Safer Opioids? ACS central science 10 (8) (2024)
Alexa Strauss, Alberto J Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada, Melanie Kristt, Anisul Arefin, Kevin Huynh, Dagan C Marx, Kristen Gilliland, Bruce J Melancon, Marta Filizola, Joel R Meyerson, Joshua Levitz
Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization. Nature communications 15 (1) (2024)
Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R. Science advances 10 (16) (2024)
Kevin Felt, Madeleine Stauffer, Leslie Salas-Estrada, Peter R Guzzo, Dejian Xie, Jinkun Huang, Marta Filizola, Sudha Chakrapani
Structural basis for partial agonism in 5-HT 3A receptors. Nature structural & molecular biology (2024)
Davide Provasi, Marta Filizola
Enhancing Opioid Bioactivity Predictions through Integration of Ligand-Based and Structure-Based Drug Discovery Strategies with Transfer and Deep Learning Techniques. bioRxiv : the preprint server for biology (2023)
Leslie Salas-Estrada, Davide Provasi, Xing Qiu, Husnu Ümit Kaniskan, Xi-Ping Huang, Jeffrey F DiBerto, João Marcelo Lamim Ribeiro, Jian Jin, Bryan L Roth, Marta Filizola
De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep-Learning Framework. Journal of chemical information and modeling (2023)
Davide Provasi, Marta Filizola
Enhancing Opioid Bioactivity Predictions through Integration of Ligand-Based and Structure-Based Drug Discovery Strategies with Transfer and Deep Learning Techniques. The journal of physical chemistry. B (2023)
Soumyo Sen, Aleksandar Spasic, Anjana Sinha, Jialing Wang, Martin Bush, Jihong Li, Dragana Nešić, Yuchen Zhou, Gabriella Angiulli, Paul Morgan, Leslie Salas-Estrada, Junichi Takagi, Thomas Walz, Barry S Coller, Marta Filizola
Structure-Based Discovery of a Novel Class of Small-Molecule Pure Antagonists of Integrin αVβ3. Journal of chemical information and modeling 62 (22) (2022)
João Marcelo Lamim Ribeiro, Davide Provasi, Marta Filizola
A combination of machine learning and infrequent metadynamics to efficiently predict kinetic rates, transition states, and molecular determinants of drug dissociation from G protein-coupled receptors. The Journal of chemical physics 153 (12) (2021)
Shashidhar S Jatiani, Stephanie Christie, Violetta V Leshchenko, Rinku Jain, Abhijeet Kapoor, Paola Bisignano, Clement Lee, H Ümit Kaniskan, Donna Edwards, Fanye Meng, Alessandro Laganà, Youssef Youssef, Adrian Wiestner, Lapo Alinari, Jian Jin, Marta Filizola, Aneel K Aggarwal, Samir Parekh
SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (16) (2021)
Soumen Chakraborty, Jeffrey F DiBerto, Abdelfattah Faouzi, Sarah M Bernhard, Anna M Gutridge, Steven Ramsey, Yuchen Zhou, Davide Provasi, Nitin Nuthikattu, Rahul Jilakara, Melissa N F Nelson, Wesley B Asher, Shainnel O Eans, Lisa L Wilson, Satyanarayana M Chintala, Marta Filizola, Richard M Van Rijn, Elyssa B Margolis, Bryan L Roth, Jay P McLaughlin, Tao Che, Dalibor Sames, Jonathan A Javitch, Susruta Majumdar
A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects. Journal of medicinal chemistry 64 (18) (2021)
Yuchen Zhou, Steven Ramsey, Davide Provasi, Amal El Daibani, Kevin Appourchaux, Soumen Chakraborty, Abhijeet Kapoor, Tao Che, Susruta Majumdar, Marta Filizola
Predicted Mode of Binding to and Allosteric Modulation of the μ-Opioid Receptor by Kratom's Alkaloids with Reported Antinociception In Vivo. Biochemistry 60 (18) (2020)
Ismael Rodríguez-Espigares, Mariona Torrens-Fontanals, Johanna K S Tiemann, David Aranda-García, Juan Manuel Ramírez-Anguita, Tomasz Maciej Stepniewski, Nathalie Worp, Alejandro Varela-Rial, Adrián Morales-Pastor, Brian Medel-Lacruz, Gáspár Pándy-Szekeres, Eduardo Mayol, Toni Giorgino, Jens Carlsson, Xavier Deupi, Slawomir Filipek, Marta Filizola, José Carlos Gómez-Tamayo, Angel Gonzalez, Hugo Gutiérrez-de-Terán, Mireia Jiménez-Rosés, Willem Jespers, Jon Kapla, George Khelashvilli, Peter Kolb, Dorota Latek, Maria Marti-Solano, Pierre Matricon, Minos-Timotheos Matsoukas, Przemyslaw Miszta, Mireia Olivella, Laura Perez-Benito, Davide Provasi, Santiago Ríos, Iván R Torrecillas, Jessica Sallander, Agnieszka Sztyler, Silvana Vasile, Harel Weinstein, Ulrich Zachariae, Peter W Hildebrand, Gianni De Fabritiis, Ferran Sanz, David E Gloriam, Arnau Cordomi, Ramon Guixà-Gonzaléz, Jana Selent
GPCRmd uncovers the dynamics of the 3D-GPCRome. Nature methods 17 (8) (2020)
Abhijeet Kapoor, Davide Provasi, Marta Filizola
Atomic-Level Characterization of the Methadone-Stabilized Active Conformation of µ-Opioid Receptor. Molecular pharmacology 98 (4) (2020)
Xiaohu Hu, Yibo Wang, Amanda Hunkele, Davide Provasi, Gavril W Pasternak, Marta Filizola
Kinetic and thermodynamic insights into sodium ion translocation through the μ-opioid receptor from molecular dynamics and machine learning analysis. PLoS computational biology 15 (1) (2019)
Sandip Basak, Yvonne Gicheru, Abhijeet Kapoor, Megan L Mayer, Marta Filizola, Sudha Chakrapani
Molecular mechanism of setron-mediated inhibition of full-length 5-HT3A receptor. Nature communications 10 (1) (2019)
Derya Meral, Davide Provasi, Marta Filizola
An efficient strategy to estimate thermodynamics and kinetics of G protein-coupled receptor activation using metadynamics and maximum caliber. The Journal of chemical physics 149 (22) (2019)
Derya Meral, Davide Provasi, Diego Prada-Gracia, Jan Möller, Kristen Marino, Martin J Lohse, Marta Filizola
Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations. Scientific reports 8 (1) (2018)
Taylor E T Hughes, David T Lodowski, Kevin W Huynh, Aysenur Yazici, John Del Rosario, Abhijeet Kapoor, Sandip Basak, Amrita Samanta, Xu Han, Sudha Chakrapani, Z Hong Zhou, Marta Filizola, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM. Nature structural & molecular biology 25 (1) (2018)
Abhijeet Kapoor, Gerard Martinez-Rosell, Davide Provasi, Gianni de Fabritiis, Marta Filizola
Dynamic and Kinetic Elements of µ-Opioid Receptor Functional Selectivity. Scientific reports 7 (1) (2017)
Rachel Saylor Crowley, Andrew P Riley, Alexander M Sherwood, Chad E Groer, Nirajmohan Shivaperumal, Miguel Biscaia, Kelly Paton, Sebastian Schneider, Davide Provasi, Bronwyn M Kivell, Marta Filizola, Thomas Edward Prisinzano
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability. Journal of medicinal chemistry 59 (24) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Marta Filizola