Georges Mer

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 13

Top Topics

Molecular Dynamics Simulations

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Sowmiya Palani, Yuka Machida, Julia R Alvey, Vandana Mishra, Allison L Welter, Gaofeng Cui, Benoît Bragantini, Maria Victoria Botuyan, Anh T Q Cong, Georges Mer, Matthew J Schellenberg, Yuichi J Machida
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes. Nature communications 15 (1) (2024)
Sowmiya Palani, Yuka Machida, Julia R Alvey, Vandana Mishra, Allison L Welter, Gaofeng Cui, Benoît Bragantini, Maria Victoria Botuyan, Anh T Q Cong, Georges Mer, Matthew J Schellenberg, Yuichi J Machida
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes. Nature communications 15 (1) (2024)
Sowmiya Palani, Yuka Machida, Julia R Alvey, Vandana Mishra, Allison L Welter, Gaofeng Cui, Benoît Bragantini, Maria Victoria Botuyan, Anh T Q Cong, Georges Mer, Matthew J Schellenberg, Yuichi J Machida
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes. Nature communications 15 (1) (2024)
Sowmiya Palani, Yuka Machida, Julia R Alvey, Vandana Mishra, Allison L Welter, Gaofeng Cui, Benoît Bragantini, Maria Victoria Botuyan, Anh T Q Cong, Georges Mer, Matthew J Schellenberg, Yuichi J Machida
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes. Nature communications 15 (1) (2024)
Gaofeng Cui, Maria Victoria Botuyan, Pascal Drané, Qi Hu, Benoît Bragantini, James R Thompson, David J Schuller, Michael T Perfetti, Lindsey I James, Stephen V Frye, Dipanjan Chowdhury, Georges Mer
An autoinhibited state of 53BP1 revealed by chemical probes and protein engineering. bioRxiv : the preprint server for biology (2023)
Gaofeng Cui, Maria Victoria Botuyan, Pascal Drané, Qi Hu, Benoît Bragantini, James Robert Thompson, David J Schuller, Alexandre Detappe, Michael T Perfetti, Lindsey I James, Stephen V Frye, Dipanjan Chowdhury, Georges Mer
An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering. Nature communications 14 (1) (2023)
Gaofeng Cui, Maria Victoria Botuyan, Pascal Drané, Qi Hu, Benoît Bragantini, James R Thompson, David J Schuller, Michael T Perfetti, Lindsey I James, Stephen V Frye, Dipanjan Chowdhury, Georges Mer
An autoinhibited state of 53BP1 revealed by chemical probes and protein engineering. bioRxiv : the preprint server for biology (2023)
Chunling Hu, Anil Belur Nagaraj, Hermela Shimelis, Gemma Montalban, Kun Y Lee, Huaizhi Huang, Carolyn A Lumby, Jie Na, Lisa R Susswein, Maegan E Roberts, Megan L Marshall, Susan Hiraki, Holly LaDuca, Elizabeth C Chao, Amal Yussuf, Tina Pesaran, Susan L Neuhausen, Christopher A Haiman, Peter Kraft, Sara Lindström, Julie R Palmer, Lauren R Teras, Celine M Vachon, Song Yao, Irene M Ong, Katherine L Nathanson, Jeffrey N Weitzel, Nicholas J Boddicker, Rohan Gnanaolivu, Eric C Polley, Georges Mer, Gaofeng Cui, Rachid Karam, Marcy E Richardson, Susan M Domchek, Siddhartha Yadav, Kathleen S Hruska, Jill S Dolinsky, John S Weroha, Steven N Hart, Jacques Simard, Jean-Yves Masson, Yuan-Ping Pang, Fergus J Couch
Functional and clinical characterization of variants of uncertain significance identifies a hotspot for inactivating missense variants in RAD51C. Cancer research (2023)
Xiangyu Zeng, Fei Zhao, Gaofeng Cui, Yong Zhang, Rajashree A Deshpande, Yuping Chen, Min Deng, Jake A Kloeber, Yu Shi, Qin Zhou, Chao Zhang, Jing Hou, Wootae Kim, Xinyi Tu, Yuanliang Yan, Zhijie Xu, Lifeng Chen, Huanyao Gao, Guijie Guo, Jiaqi Liu, Qian Zhu, Yueyu Cao, Jinzhou Huang, Zheming Wu, Shouhai Zhu, Ping Yin, Kuntian Luo, Georges Mer, Tanya T Paull, Jian Yuan, Kaixiong Tao, Zhenkun Lou
METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma. Nature cancer 3 (9) (2022)
Qi Hu, Maria Victoria Botuyan, Debiao Zhao, Gaofeng Cui, Elie Mer, Georges Mer
Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Nature 596 (7872) (2021)
Dejie Wang, Jian Ma, Maria Victoria Botuyan, Gaofeng Cui, Yuqian Yan, Donglin Ding, Yingke Zhou, Eugene W Krueger, Jiang Pei, Xiaosheng Wu, Liguo Wang, Huadong Pei, Mark A McNiven, Dingwei Ye, Georges Mer, Zhenlin Huang
ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Science advances 7 (25) (2021)
Jian Ma, Qing Shi, Gaofeng Cui, Haoyue Sheng, Maria Victoria Botuyan, Yingke Zhou, Yuqian Yan, Yundong He, Liguo Wang, Yuzhuo Z Wang, Georges Mer, Dingwei Ye, Chenji Wang, Zhenlin Huang
SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition. Nature communications 12 (1) (2021)
Maria Victoria Botuyan, Gaofeng Cui, Pascal Drané, Catarina Oliveira, Alexandre Detappe, Marie Eve Brault, Nishita Parnandi, Shweta Chaubey, James R Thompson, Benoît Bragantini, Debiao Zhao, J Ross Chapman, Dipanjan Chowdhury, Georges Mer
Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nature structural & molecular biology 25 (7) (2018)