Gong Chen

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 52

Top Venues

Organic letters

Journal of the American Chemical Society

Angewandte Chemie (International ed. in English)

The Journal of organic chemistry

Pennsylvania State University University Park

Columbia University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Pennsylvania State University University Park Jun 06 2008

United States

Associate Professor :: Chemistry

Memorial Sloan-Kettering Cancer Center Jan 01 2005 - May 31 2008

United States

Postdoc :: Molecular Pharmacology & Chemistry

Education History

Columbia University Aug 20 1999 - Aug 31 2004

United States

PHD :: Chemistry

Nanjing University Sep 01 1994 - Aug 31 1998

China

BSC :: chemistry

Publications

Yi Huang, Shi-Yang Zhu, Gang He, Gong Chen, Hao Wang
Synthesis of N-H Aziridines from Unactivated Olefins Using Hydroxylamine- O -Sulfonic Acids as Aminating Agent. The Journal of organic chemistry 89 (9) (2024)
Pan Guo, Xin Chu, Chengjin Wu, Tianjiao Qiao, Wenli Guan, Chuanzheng Zhou, Tao Wang, Changlin Tian, Gang He, Gong Chen
Peptide Stapling by Crosslinking Two Amines with α-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers. Angewandte Chemie (International ed. in English) (2024)
Pan Guo, Xin Chu, Chengjin Wu, Tianjiao Qiao, Wenli Guan, Chuanzheng Zhou, Tao Wang, Changlin Tian, Gang He, Gong Chen
Peptide Stapling by Crosslinking Two Amines with α-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers. Angewandte Chemie (International ed. in English) 63 (16) (2024)
Pan Guo, Xin Chu, Chengjin Wu, Tianjiao Qiao, Wenli Guan, Chuanzheng Zhou, Tao Wang, Changlin Tian, Gang He, Gong Chen
Peptide Stapling by Crosslinking Two Amines with α-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers. Angewandte Chemie (International ed. in English) 63 (16) (2024)
Pan Guo, Xin Chu, Chengjin Wu, Tianjiao Qiao, Wenli Guan, Chuanzheng Zhou, Tao Wang, Changlin Tian, Gang He, Gong Chen
Peptide Stapling by Crosslinking Two Amines with α-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers. Angewandte Chemie (International ed. in English) 63 (16) (2024)
Shaokun Cai, Hong Tang, Bo Li, Yingbo Shao, Danqi Zhang, Hanliang Zheng, Tianjiao Qiao, Xin Chu, Gang He, Xiao-Song Xue, Gong Chen
Formaldehyde-Mediated Hydride Liberation of Alkylamines for Intermolecular Reactions in Hexafluoroisopropanol. Journal of the American Chemical Society 146 (9) (2024)
Pan Guo, Xin Chu, Chengjin Wu, Tianjiao Qiao, Wenli Guan, Chuanzheng Zhou, Tao Wang, Changlin Tian, Gang He, Gong Chen
Peptide Stapling by Crosslinking Two Amines with α-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers. Angewandte Chemie (International ed. in English) 63 (16) (2024)
Shaokun Cai, Hong Tang, Bo Li, Yingbo Shao, Danqi Zhang, Hanliang Zheng, Tianjiao Qiao, Xin Chu, Gang He, Xiao-Song Xue, Gong Chen
Formaldehyde-Mediated Hydride Liberation of Alkylamines for Intermolecular Reactions in Hexafluoroisopropanol. Journal of the American Chemical Society (2024)
Yi Huang, Shi-Yang Zhu, Gang He, Gong Chen, Hao Wang
Synthesis of N-H Aziridines from Unactivated Olefins Using Hydroxylamine- O -Sulfonic Acids as Aminating Agent. The Journal of organic chemistry (2024)
Yaxin Wang, Zehui Cao, Qin He, Xin Huang, Jiaxi Liu, Helfried Neumann, Gong Chen, Matthias Beller
Activation of perfluoroalkyl iodides by anions: extending the scope of halogen bond activation to C(sp 3 )-H amidation, C(sp 2 )-H iodination, and perfluoroalkylation reactions. Chemical science 14 (7) (2023)
Yifei Zhou, Hongjun Li, Yi Huang, Jiahui Li, Guiyu Deng, Gong Chen, Zhen Xi, Chuanzheng Zhou
Suppression of alpha-carbon racemization in peptide synthesis based on a thiol-labile amino protecting group. Nature communications 14 (1) (2023)
Yaxin Wang, Zehui Cao, Qin He, Xin Huang, Jiaxi Liu, Helfried Neumann, Gong Chen, Matthias Beller
Activation of perfluoroalkyl iodides by anions: extending the scope of halogen bond activation to C(sp 3 )-H amidation, C(sp 2 )-H iodination, and perfluoroalkylation reactions. Chemical science 14 (7) (2023)
Yi Huang, Xiaoyan Lv, Hua-Rong Tong, Wenji He, Ziqian Bai, Hao Wang, Gang He, Gong Chen
Palladium-Catalyzed Enantioselective Directed C(sp 3 )-H Functionalization Using C 5 -Substituted 8-Aminoquinoline Auxiliaries. Organic letters 26 (1) (2023)
Peng Yang, Martynas J Širvinskas, Bo Li, Nicholas W Heller, Hua Rong, Gang He, Andrei K Yudin, Gong Chen
Teraryl Braces in Macrocycles: Synthesis and Conformational Landscape Remodeling of Peptides. Journal of the American Chemical Society (2023)
Yi Huang, Xiaoyan Lv, Hua-Rong Tong, Wenji He, Ziqian Bai, Hao Wang, Gang He, Gong Chen
Palladium-Catalyzed Enantioselective Directed C(sp 3 )-H Functionalization Using C 5 -Substituted 8-Aminoquinoline Auxiliaries. Organic letters (2023)
Xin Chu, Bo Li, Hao-Yang Liu, Xiaowei Sun, Xiaochen Yang, Gang He, Chuanzheng Zhou, Weimin Xuan, Shu-Lin Liu, Gong Chen
Bioconjugation via Hetero-Selective Clamping of Two Different Amines with ortho-Phthalaldehyde. Angewandte Chemie (International ed. in English) (2022)
Bo Li, Zhao Wan, Hanliang Zheng, Shaokun Cai, Han-Wen Tian, Hong Tang, Xin Chu, Gang He, Dong-Sheng Guo, Xiao-Song Xue, Gong Chen
Construction of Complex Macromulticyclic Peptides via Stitching with Formaldehyde and Guanidine. Journal of the American Chemical Society 144 (22) (2022)
Bo Li, Lan Wang, Xiangxiang Chen, Xin Chu, Hong Tang, Jie Zhang, Gang He, Li Li, Gong Chen
Extendable stapling of unprotected peptides by crosslinking two amines with o-phthalaldehyde. Nature communications 13 (1) (2022)
Shaokun Cai, Qikai Sun, Quanquan Wang, Gang He, Gong Chen
Ruthenium-Catalyzed Pyridine-Directed Aryl C-H Glycosylation with Glycosyl Chlorides. The Journal of organic chemistry 87 (13) (2022)
Gong Chen, Monika Raj, Andrei K Yudin
Introduction to 'Synthesis and chemical biology of macrocycles'. RSC chemical biology 3 (8) (2022)
Ziqian Bai, Shiyang Zhu, Yiyao Hu, Peng Yang, Xin Chu, Gang He, Hao Wang, Gong Chen
Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols. Nature communications 13 (1) (2022)
Xin Chu, Linhua Shen, Bo Li, Peng Yang, Chengzhuo Du, Xiao-Ye Wang, Gang He, Samir Messaoudi, Gong Chen
Construction of Peptide Macrocycles via Palladium-Catalyzed Multiple S-Arylation: An Effective Strategy to Expand the Structural Diversity of Cross-Linkers. Organic letters 23 (20) (2021)
Heng Zhang, Xiaoyan Lv, Hanrui Yu, Zibo Bai, Gong Chen, Gang He
β-Lactam Synthesis via Copper-Catalyzed Directed Aminoalkylation of Unactivated Alkenes with Cyclobutanone O-Benzoyloximes. Organic letters 23 (9) (2021)
Hao Wang, Hoimin Jung, Fangfang Song, Shiyang Zhu, Ziqian Bai, Danye Chen, Gang He, Sukbok Chang, Gong Chen
Nitrene-mediated intermolecular N-N coupling for efficient synthesis of hydrazides. Nature chemistry 13 (4) (2021)
Peng Yang, Xuan Wang, Bo Li, Yixuan Yang, Jinfeng Yue, Yanrui Suo, Huarong Tong, Gang He, Xiaojie Lu, Gong Chen
Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation in solution and on DNA. Chemical science 12 (16) (2021)
Bo Li, Hong Tang, Aneta Turlik, Zhao Wan, Xiao-Song Xue, Li Li, Xiaoxiao Yang, Jiuyuan Li, Gang He, Kendall N Houk, Gong Chen
Cooperative Stapling of Native Peptides at Lysine and Tyrosine or Arginine with Formaldehyde. Angewandte Chemie (International ed. in English) 60 (12) (2021)
Qikai Sun, Huixing Zhang, Quanquan Wang, Tianjiao Qiao, Gang He, Gong Chen
Stereoselective Synthesis of C-Vinyl Glycosides via Palladium-Catalyzed C-H Glycosylation of Alkenes. Angewandte Chemie (International ed. in English) 60 (36) (2021)
Xiafei Hu, Xiangxiang Chen, Bo Li, Gang He, Gong Chen
Construction of Peptide Macrocycles via Radical-Mediated Intramolecular C-H Alkylations. Organic letters 23 (3) (2021)
Zhiqiang Deng, Zhenxiang Zhao, Gang He, Gong Chen
Photoredox-Mediated Mono- and Difluorination of Remote Unactivated Methylene C(sp3)-H Bonds of N-Alkyl Sulfonamides. Organic letters 23 (9) (2021)
Qiong Li, Jie Huang, Gong Chen, Shui-Bo Wang
Copper-catalyzed ortho-C(sp2)-H amination of benzamides and picolinamides with alkylamines using oxygen as a green oxidant. Organic & biomolecular chemistry 18 (25) (2021)
Boyang Han, Bo Li, Liping Qi, Peng Yang, Gang He, Gong Chen
Construction of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Picolinamide-Directed Intramolecular C(sp2)-H Arylation. Organic letters 22 (17) (2020)
Zibo Bai, Heng Zhang, Hao Wang, Hanrui Yu, Gong Chen, Gang He
Enantioselective Alkylamination of Unactivated Alkenes under Copper Catalysis. Journal of the American Chemical Society 143 (2) (2020)
Xinghua Li, Liping Qi, Bo Li, Zhenxiang Zhao, Gang He, Gong Chen
Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular C(sp3)-H Arylation of N-Methyl Alanine at C-Termini. Organic letters 22 (15) (2020)
Yingqian Zhang, Chuanlong Zang, Guoce An, Mengdi Shang, Zenghui Cui, Gong Chen, Zhen Xi, Chuanzheng Zhou
Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones. Nature communications 11 (1) (2020)
Bo Li, Jie Zhang, Li Li, Gong Chen
A rapid and sensitive method for chiroptical sensing of α-amino acids via click-like labeling with o-phthalaldehyde and p-toluenethiol. Chemical science 12 (7) (2020)
Hao Wang, Yoonsu Park, Ziqian Bai, Sukbok Chang, Gang He, Gong Chen
Iridium-Catalyzed Enantioselective C(sp3)-H Amidation Controlled by Attractive Noncovalent Interactions. Journal of the American Chemical Society 141 (17) (2019)
Zhiguo Zhang, Xiang Li, Mengmeng Song, Yameng Wan, Dan Zheng, Guisheng Zhang, Gong Chen
Selective Removal of Aminoquinoline Auxiliary by IBX Oxidation. The Journal of organic chemistry 84 (20) (2019)
Bo Li, Xinghua Li, Boyang Han, Zhijie Chen, Xuekai Zhang, Gang He, Gong Chen
Construction of Natural-Product-Like Cyclophane-Braced Peptide Macrocycles via sp3 C-H Arylation. Journal of the American Chemical Society 141 (23) (2019)
Xiaoping Chen, Farong Ye, Xiaosheng Luo, Xueyi Liu, Jie Zhao, Siyao Wang, Qingqing Zhou, Gong Chen, Ping Wang
Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation. Journal of the American Chemical Society 141 (45) (2019)
Zhiqiang Deng, Guo-Xing Li, Gang He, Gong Chen
Photoredox-Mediated Remote C(sp3)-H Heteroarylation of N-Alkyl Sulfonamides. The Journal of organic chemistry 84 (24) (2019)
Xue-Qing Mou, Feng-Ming Rong, Heng Zhang, Gong Chen, Gang He
Copper(I)-Catalyzed Enantioselective Intramolecular Aminotrifluoromethylation of O-Homoallyl Benzimidates. Organic letters 21 (12) (2019)
Guo-Xing Li, Xiafei Hu, Gang He, Gong Chen
Photoredox-mediated remote C(sp3)-H heteroarylation of free alcohols. Chemical science 10 (3) (2018)
Hao Wang, Zibo Bai, Tangqian Jiao, Zhiqiang Deng, Huarong Tong, Gang He, Qian Peng, Gong Chen
Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand. Journal of the American Chemical Society 140 (10) (2018)
Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He, Xiangbing Qi, Weijun Shen, Peng Liu, Gong Chen
A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C-H arylation. Nature chemistry 10 (5) (2018)
Delong Mu, Gang He, Gong Chen
Palladium-Catalyzed ortho C-H Arylation of Benzaldehydes Using ortho-Sulfinyl Aniline as Transient Auxiliary. Chemistry, an Asian journal 13 (17) (2018)
Yaxin Wang, Xiafei Hu, Cristian A Morales-Rivera, Guo-Xing Li, Xin Huang, Gang He, Peng Liu, Gong Chen
Epimerization of Tertiary Carbon Centers via Reversible Radical Cleavage of Unactivated C(sp3)-H Bonds. Journal of the American Chemical Society 140 (30) (2018)
Zhengwei Guo, Man Li, Xue-Qing Mou, Gang He, Xiao-Song Xue, Gong Chen
Radical C-H Arylation of Oxazoles with Aryl Iodides: dppf as an Electron-Transfer Mediator for Cs2CO3. Organic letters 20 (6) (2018)
Delong Mu, Xinmou Wang, Gong Chen, Gang He
Iridium-Catalyzed ortho-C(sp2)-H Amidation of Benzaldehydes with Organic Azides. The Journal of organic chemistry 82 (8) (2017)
Yaxin Wang, Junhua Wang, Guo-Xing Li, Gang He, Gong Chen
Halogen-Bond-Promoted Photoactivation of Perfluoroalkyl Iodides: A Photochemical Protocol for Perfluoroalkylation Reactions. Organic letters 19 (6) (2017)
Guo-Xing Li, Cristian A Morales-Rivera, Fang Gao, Yaxin Wang, Gang He, Peng Liu, Gong Chen
A unified photoredox-catalysis strategy for C(sp3)-H hydroxylation and amidation using hypervalent iodine. Chemical science 8 (10) (2017)
Gang He, Yingsheng Zhao, Shuyu Zhang, Chengxi Lu, Gong Chen
Correction to "Highly Efficient Syntheses of Azetidines, Pyrrolidines, and Indolines via Palladium-Catalyzed Intramolecular Amination of C(sp3)-H and C(sp2)-H Bonds at γ and δ Positions". Journal of the American Chemical Society 139 (1) (2016)
Hao Wang, Hua-Rong Tong, Gang He, Gong Chen
An Enantioselective Bidentate Auxiliary Directed Palladium-Catalyzed Benzylic C-H Arylation of Amines Using a BINOL Phosphate Ligand. Angewandte Chemie (International ed. in English) 55 (49) (2016)

Gong Chen.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Gong Chen