Xiaojie Lu

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 48

Top Topics

High Efficiency

Circulating Tumor

Top Venues

Organic letters

Bioconjugate chemistry

Journal of medicinal chemistry

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Shaozhao Qin, Lijian Feng, Qingyi Zhao, Ziqin Yan, Xilin Lyu, Kaige Li, Baiyang Mu, Yujie Chen, Weiwei Lu, Chao Wang, Yanrui Suo, Jinfeng Yue, Mengqing Cui, Yingjie Li, Yujun Zhao, Zhiqiang Duan, Jidong Zhu, Xiaojie Lu
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach. Journal of medicinal chemistry 67 (2) (2024)
Dongliang Guan, Jiaxiang Liu, Feifei Chen, Jian Li, Xiaowen Wang, Weiwei Lu, Yanrui Suo, Feng Tang, Lefu Lan, Xiaojie Lu, Wei Huang
Correction to "A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria". Journal of medicinal chemistry (2024)
Yanrui Suo, Kaige Li, Xing Ling, Kenian Yan, Weiwei Lu, Jinfeng Yue, Xiao-Hua Chen, Zhiqiang Duan, Xiaojie Lu
Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library. Bioconjugate chemistry 35 (8) (2024)
Xudong Wang, Ying Zhu, Qingyi Zhao, Weiwei Lu, Yechun Xu, Hangchen Hu, Xiaojie Lu
Chemical Space Profiling of SARS-CoV-2 PL pro Using DNA-Encoded Focused Libraries. ACS medicinal chemistry letters 15 (4) (2024)
Xudong Wang, Ying Zhu, Qingyi Zhao, Weiwei Lu, Yechun Xu, Hangchen Hu, Xiaojie Lu
Chemical Space Profiling of SARS-CoV-2 PL pro Using DNA-Encoded Focused Libraries. ACS medicinal chemistry letters 15 (4) (2024)
Dongliang Guan, Jiaxiang Liu, Feifei Chen, Jian Li, Xiaowen Wang, Weiwei Lu, Yanrui Suo, Feng Tang, Lefu Lan, Xiaojie Lu, Wei Huang
A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria. Journal of medicinal chemistry 67 (5) (2024)
Xing Ling, Sixiu Liu, Yixuan Yang, Qian Dong, Lisa A Marcaurelle, Wei Huang, Yun Ding, Xuan Wang, Xiaojie Lu
Correction to "Modular Click Assembly DNA-Encoded Glycoconjugate Libraries with on-DNA Functional Group Transformations". Bioconjugate chemistry (2024)
Xudong Wang, Ying Zhu, Qingyi Zhao, Weiwei Lu, Yechun Xu, Hangchen Hu, Xiaojie Lu
Chemical Space Profiling of SARS-CoV-2 PL pro Using DNA-Encoded Focused Libraries. ACS medicinal chemistry letters 15 (4) (2024)
Yuhan Lv, Min Wu, Weiwei Lu, Meiying Cui, Jiaxiang Liu, Wei Yi, Xuan Wang, Xiaojie Lu
Rhodium-Promoted C-H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes. Organic letters (2024)
Dongliang Guan, Jiaxiang Liu, Feifei Chen, Jian Li, Xiaowen Wang, Weiwei Lu, Yanrui Suo, Feng Tang, Lefu Lan, Xiaojie Lu, Wei Huang
A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria. Journal of medicinal chemistry 67 (5) (2024)
Shaozhao Qin, Lijian Feng, Qingyi Zhao, Ziqin Yan, Xilin Lyu, Kaige Li, Baiyang Mu, Yujie Chen, Weiwei Lu, Chao Wang, Yanrui Suo, Jinfeng Yue, Mengqing Cui, Yingjie Li, Yujun Zhao, Zhiqiang Duan, Jidong Zhu, Xiaojie Lu
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach. Journal of medicinal chemistry 67 (2) (2024)
Dongliang Guan, Jiaxiang Liu, Feifei Chen, Jian Li, Xiaowen Wang, Weiwei Lu, Yanrui Suo, Feng Tang, Lefu Lan, Xiaojie Lu, Wei Huang
Correction to "A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria". Journal of medicinal chemistry 67 (7) (2024)
Yanrui Suo, Kaige Li, Xing Ling, Kenian Yan, Weiwei Lu, Jinfeng Yue, Xiao-Hua Chen, Zhiqiang Duan, Xiaojie Lu
Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library. Bioconjugate chemistry 35 (8) (2024)
Shaozhao Qin, Lijian Feng, Qingyi Zhao, Ziqin Yan, Xilin Lyu, Kaige Li, Baiyang Mu, Yujie Chen, Weiwei Lu, Chao Wang, Yanrui Suo, Jinfeng Yue, Mengqing Cui, Yingjie Li, Yujun Zhao, Zhiqiang Duan, Jidong Zhu, Xiaojie Lu
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach. Journal of medicinal chemistry (2024)
Dongliang Guan, Jiaxiang Liu, Feifei Chen, Jian Li, Xiaowen Wang, Weiwei Lu, Yanrui Suo, Feng Tang, Lefu Lan, Xiaojie Lu, Wei Huang
A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria. Journal of medicinal chemistry 67 (5) (2024)
Xing Ling, Sixiu Liu, Yixuan Yang, Qian Dong, Lisa A Marcaurelle, Wei Huang, Yun Ding, Xuan Wang, Xiaojie Lu
Correction to "Modular Click Assembly DNA-Encoded Glycoconjugate Libraries with on-DNA Functional Group Transformations". Bioconjugate chemistry 35 (4) (2024)
Yuhan Lv, Min Wu, Weiwei Lu, Meiying Cui, Jiaxiang Liu, Wei Yi, Xuan Wang, Xiaojie Lu
Rhodium-Promoted C-H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes. Organic letters 26 (23) (2024)
Yanrui Suo, Kaige Li, Xing Ling, Kenian Yan, Weiwei Lu, Jinfeng Yue, Xiao-Hua Chen, Zhiqiang Duan, Xiaojie Lu
Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library. Bioconjugate chemistry (2024)
Chang Shen, Peijia Xu, Changfa Zhang, Zhaoming Su, Bin Shan, Rui Li, Qibang Sui, Keke Zhang, Zhengyang Chen, Jingyi Zhou, Xiaojie Lu, Kaixian Chen, Mingyue Zheng, Sulin Zhang, Hui Hou
Structure-Activity Relationship Study of 1 H -Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists. ACS medicinal chemistry letters 14 (8) (2023)
Xin Wen, Minmin Zhang, Zhiqiang Duan, Yanrui Suo, Weiwei Lu, Rui Jin, Baiyang Mu, Kaige Li, Xu Zhang, Linghua Meng, Yu Hong, Xingyu Wang, Hangchen Hu, Jian Zhu, Weixiao Song, Aijun Shen, Xiaojie Lu
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library. Journal of medicinal chemistry (2023)
Yandan Bao, Minyan Xing, Naylor Matthew, Xiao-Hua Chen, Xuan Wang, Xiaojie Lu
Macrocyclizing DNA-Linked Peptides via Three-Component Cyclization and Photoinduced Chemistry. Organic letters (2023)
Lifan Chen, Zisheng Fan, Jie Chang, Ruirui Yang, Hui Hou, Hao Guo, Yinghui Zhang, Tianbiao Yang, Chenmao Zhou, Qibang Sui, Zhengyang Chen, Chen Zheng, Xinyue Hao, Keke Zhang, Rongrong Cui, Zehong Zhang, Hudson Ma, Yiluan Ding, Naixia Zhang, Xiaojie Lu, Xiaomin Luo, Hualiang Jiang, Sulin Zhang, Mingyue Zheng
Sequence-based drug design as a concept in computational drug design. Nature communications 14 (1) (2023)
Qingyi Zhao, Yandan Bao, Dawen Niu, Xuan Wang, Xiaojie Lu
The Development of DNA-Compatible S-Glycosyl Transformations. Organic letters (2023)
Xing Ling, Sixiu Liu, Yixuan Yang, Qian Dong, Lisa A Marcaurelle, Wei Huang, Yun Ding, Xuan Wang, Xiaojie Lu
Modular Click Assembly DNA-Encoded Glycoconjugate Libraries with on-DNA Functional Group Transformations. Bioconjugate chemistry (2023)
Mengnisa Seydimemet, Yixuan Yang, Yuhan Lv, Jiaxiang Liu, Ziqin Yan, Yujun Zhao, Xuan Wang, Xiaojie Lu
Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries. ACS medicinal chemistry letters 14 (8) (2023)
Siyu He, Linjie Li, Rui Jin, Xiaojie Lu
Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions. Journal of medicinal chemistry (2023)
Lulu Jiang, Sixiu Liu, Xinglong Jia, Qinting Gong, Xin Wen, Weiwei Lu, Jintong Yang, Xinyuan Wu, Xuan Wang, Yanrui Suo, Yilin Li, Motonari Uesugi, Zhi-Bei Qu, Min-Jia Tan, Xiaojie Lu, Lu Zhou
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries. Journal of the American Chemical Society (2023)
Yue Zhang, Shengdi Xia, Wen-Xia Shi, Bizhen Lin, Xiao-Can Su, Weiwei Lu, Xinyuan Wu, Xuan Wang, Xiaojie Lu, Ming Yan, Xue-Jing Zhang
Radical C-H Sulfonation of Arenes: Its Applications on Bioactive and DNA-Encoded Molecules. Organic letters 24 (43) (2022)
Sixiu Liu, Jingjing Qi, Weiwei Lu, Xuan Wang, Xiaojie Lu
Correction to "Synthetic Studies toward DNA-Encoded Heterocycles Based on the On-DNA Formation of α, β-Unsaturated Ketones". Organic letters 24 (25) (2022)
Yanrui Suo, Min Xu, Meimei Sun, Weiwei Lu, Xuan Wang, Xiaojie Lu
Ruthenium-Mediated [2 + 2 + 2] Cyclization: A Route to Forge Indane and Isoindoline Core and Its Application in DNA-Encoded Library Technology. Organic letters (2022)
Linjie Li, Mingbo Su, Weiwei Lu, Hongzhi Song, Jiaxiang Liu, Xin Wen, Yanrui Suo, Jingjing Qi, Xiaomin Luo, Yu-Bo Zhou, Xin-Hua Liao, Jia Li, Xiaojie Lu
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins. ACS medicinal chemistry letters 13 (10) (2022)
Wang Liu, Xiaopeng Bai, Liping Song, Xuan Wang, Xiaojie Lu
Constructing Head-to-Tail Cyclic Peptide DNA-Encoded Libraries Using Two-Directional Synthesis Strategy. Bioconjugate chemistry 33 (4) (2022)
Xinyuan Wu, Yujie Chen, Weiwei Lu, Rui Jin, Xiaojie Lu
Quantitative Validation and Application of the Photo-Cross-Linking Selection for Double-Stranded DNA-Encoded Libraries. Bioconjugate chemistry 33 (10) (2022)
Jingjing Qi, Sixiu Liu, Mengnisa Seydimemet, Xuan Wang, Xiaojie Lu
A General Set of DNA-Compatible Reactions for Preparing DNA-Tagged Multisubstituted Pyrroles. Bioconjugate chemistry 32 (11) (2021)
Bizhen Lin, Weiwei Lu, Zhen-Yu Chen, Yue Zhang, Yin-Zhe Duan, Xiaojie Lu, Ming Yan, Xue-Jing Zhang
Enhancing the Potential of Miniature-Scale DNA-Compatible Radical Reactions via an Electron Donor-Acceptor Complex and a Reversible Adsorption to Solid Support Strategy. Organic letters 23 (19) (2021)
Bing Xia, G Joseph Franklin, Xiaojie Lu, Katie L Bedard, LaShadric C Grady, Jennifer D Summerfield, Eric X Shi, Bryan W King, Kenneth E Lind, Cynthia Chiu, Eleanor Watts, Vera Bodmer, Xiaopeng Bai, Lisa A Marcaurelle
DNA-Encoded Library Hit Confirmation: Bridging the Gap Between On-DNA and Off-DNA Chemistry. ACS medicinal chemistry letters 12 (7) (2021)
Xuan Wang, Jiaxiang Liu, Ziqin Yan, Xiaohong Liu, Sixiu Liu, Yanrui Suo, Weiwei Lu, Jinfeng Yue, Kaixian Chen, Hualiang Jiang, Yujun Zhao, Mingyue Zheng, Dongcheng Dai, Xiaojie Lu
Diversified strategy for the synthesis of DNA-encoded oxindole libraries. Chemical science 12 (8) (2021)
Xing Ling, Weiwei Lu, Lin Miao, Lisa A Marcaurelle, Xuan Wang, Yun Ding, Xiaojie Lu
Divergent On-DNA Transformations from DNA-Linked Piperidones. The Journal of organic chemistry (2021)
Peng Yang, Xuan Wang, Bo Li, Yixuan Yang, Jinfeng Yue, Yanrui Suo, Huarong Tong, Gang He, Xiaojie Lu, Gong Chen
Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation in solution and on DNA. Chemical science 12 (16) (2021)
Jing Chai, Xiaojie Lu, Christopher C Arico-Muendel, Yun Ding, Michael P Pollastri
Application of l-Threonine Aldolase to on-DNA Reactions. Bioconjugate chemistry 32 (9) (2021)
Sixiu Liu, Jingjing Qi, Weiwei Lu, Xuan Wang, Xiaojie Lu
Synthetic Studies toward DNA-Encoded Heterocycles Based on the On-DNA Formation of α,β-Unsaturated Ketones. Organic letters 23 (3) (2021)
Wenting Wu, Zhen Sun, Xuan Wang, Xiaojie Lu, Dongcheng Dai
Construction of Thiazole-Fused Dihydropyrans via Formal [4 + 2] Cycloaddition Reaction on DNA. Organic letters 22 (8) (2020)
Xin Wen, Zhiqiang Duan, Jiaxiang Liu, Weiwei Lu, Xiaojie Lu
On-DNA Cross-Dehydrogenative Coupling Reaction toward the Synthesis of Focused DNA-Encoded Tetrahydroisoquinoline Libraries. Organic letters 22 (15) (2020)
Xuan Wang, Hui Sun, Jiaxiang Liu, Wenge Zhong, Mingqiang Zhang, Hu Zhou, Dongcheng Dai, Xiaojie Lu
Palladium-Promoted DNA-Compatible Heck Reaction. Organic letters 21 (3) (2019)
Xuan Wang, Hui Sun, Jiaxiang Liu, Dongcheng Dai, Mingqiang Zhang, Hu Zhou, Wenge Zhong, Xiaojie Lu
Ruthenium-Promoted C-H Activation Reactions between DNA-Conjugated Acrylamide and Aromatic Acids. Organic letters 20 (16) (2018)
Hailong Li, Zhen Sun, Wenting Wu, Xuan Wang, Mingqiang Zhang, Xiaojie Lu, Wenge Zhong, Dongcheng Dai
Inverse-Electron-Demand Diels-Alder Reactions for the Synthesis of Pyridazines on DNA. Organic letters 20 (22) (2018)
Xiaojie Lu, Sarah E Roberts, George J Franklin, Christopher P Davie
On-DNA Pd and Cu promoted C-N cross-coupling reactions. MedChemComm 8 (8) (2017)
Xiaojie Lu, Lijun Fan, Christopher B Phelps, Christopher P Davie, Christine P Donahue
Ruthenium Promoted On-DNA Ring-Closing Metathesis and Cross-Metathesis. Bioconjugate chemistry 28 (6) (2017)