Grainne M O'Kane (Natasha B Leighl)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 17

Top Topics

Prognostic Factors

Top Venues

British journal of cancer

Clinical cancer research : an official journal of the American Association for Cancer Research

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer 5 (6) (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer 5 (6) (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer 5 (6) (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer (2024)
Lucy X Ma, Yifan Wang, Osvaldo Espin-Garcia, Michael J Allen, Gun Ho Jang, Amy Zhang, Anna Dodd, Stephanie Ramotar, Shawn Hutchinson, Mustapha Tehfe, Ravi Ramjeesingh, James Biagi, Julie M Wilson, Faiyaz Notta, Sandra E Fischer, George Zogopoulos, Steven Gallinger, Robert C Grant, Rama Khokha, Nathan Chan, Barbara T Grünwald, Jennifer J Knox, Grainne M O'Kane
Systemic inflammatory prognostic scores in advanced pancreatic adenocarcinoma. British journal of cancer (2023)
Manuel Lauinger, Daniel Christen, Rhena F U Klar, Carole Roubaty, Christoph E Heilig, Michael Stumpe, Jennifer J Knox, Nikolina Radulovich, Laura Tamblyn, Irene Y Xie, Peter Horak, Andrea Forschner, Michael Bitzer, Uwe A Wittel, Melanie Börries, Claudia R Ball, Christoph Heining, Hanno Glimm, Martina Fröhlich, Daniel Hübschmann, Steven Gallinger, Ralph Fritsch, Stefan Fröhling, Grainne M O'Kane, Joern Dengjel, Tilman Brummer
BRAF Δβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability. Science advances 9 (35) (2023)
Chani Stossel, Maria Raitses-Gurevich, Dikla Atias, Tamar Beller, Yulia Glick Gorman, Sharon Halperin, Eyal Peer, Robert E Denroche, Amy Zhang, Faiyaz Notta, Julie M Wilson, Grainne M O'Kane, Elina Haimov Talmoud, Nora Amison, Michael Schvimer, Seth J Salpeter, Vered Bar, Adi Zundelevich, Michael Mints, Rotem Tal, Gal Dinstag, Yaron Kinar, Yonatan Eliezer, Uri Ben-David, Nancy S Gavert, Ravid Straussman, Steven J Gallinger, Raanan Berger, Talia Golan
Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA-Associated Pancreatic Cancer in the Clinical and Preclinical Setting. Cancer discovery (2023)
Cha Len Lee, Grainne M O'Kane, Warren P Mason, Wen-Jiang Zhang, Pavlina Spiliopoulou, Aaron Richard Hansen, Robert C Grant, Jennifer J Knox, Tracy L Stockley, Gelareh Zadeh, Eric X Chen
Circulating oncometabolite 2-hydroxyglutarate (2HG) as a potential biomarker for isocitrate dehydrogenase (IDH1/2) mutant cholangiocarcinoma. Molecular cancer therapeutics (2023)
Sheron Perera, Gun Ho Jang, Robert C Grant, Faiyaz Notta, Barbara T Grünwald, Steven J Gallinger, Jennifer J Knox, Grainne M O'Kane
hENT1 as a Predictive Biomarker in PDAC-Response. Clinical cancer research : an official journal of the American Association for Cancer Research 29 (15) (2023)
Tommy Ivanics, Fiorella Murillo Perez, Marco P A W Claasen, Madhukar S Patel, Gabriela Morgenshtern, Lauren Erdman, Chaya Shwaartz, Luckshi Rajendran, Grainne M O'Kane, Bettina E Hansen, Sean P Cleary, Gonzalo Sapisochin
Dynamic risk profiling of HCC recurrence after curative intent liver resection. Hepatology (Baltimore, Md.) 76 (5) (2022)
Grainne M O'Kane, Maeve Aine Lowery
Moving the Needle on Precision Medicine in Pancreatic Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (24) (2022)
Mark K Doherty, Vincent C Tam, Mairéad Geraldine McNamara, Raymond Jang, David Hedley, Eric Chen, Neesha Dhani, Patricia Tang, Hao-Wen Sim, Grainne M O'Kane, Stephanie DeLuca, Lisa Wang, Theresa Pedutem, Jennifer J Knox
Randomised, Phase II study of selumetinib, an oral inhibitor of MEK, in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer. British journal of cancer 127 (8) (2022)
James T Topham, Erica S Tsang, Joanna M Karasinska, Andrew Metcalfe, Hassan Ali, Steve E Kalloger, Veronika Csizmok, Laura M Williamson, Emma Titmuss, Karina Nielsen, Gian Luca Negri, Sandra Elizabeth Spencer, Gun Ho Jang, Robert E Denroche, Hui-Li Wong, Grainne M O'Kane, Richard A Moore, Andrew J Mungall, Jonathan M Loree, Faiyaz Notta, Julie M Wilson, Oliver F Bathe, Patricia A Tang, Rachel Goodwin, Gregg B Morin, Jennifer J Knox, Steven Gallinger, Janessa Laskin, Marco A Marra, Steven J M Jones, David F Schaeffer, Daniel J Renouf
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma. Nature communications 13 (1) (2022)
Sheron Perera, Gun Ho Jang, Yifan Wang, Deirdre Kelly, Michael J Allen, Amy Zhang, Robert E Denroche, Anna Dodd, Stephanie Ramotar, Shawn Hutchinson, Mustapha Tehfé, Ravi Ramjeesingh, James J Biagi, Bernard Lam, Julie M Wilson, Sandra E Fischer, George Zogopoulos, Faiyaz Notta, Steven J Gallinger, Robert C Grant, Jennifer J Knox, Grainne M O'Kane
hENT1 Expression Predicts Response to Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Ductal Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (23) (2022)
Grainne M O'Kane, Grainne M O'Kane
Systemic Therapy of Lung Cancer CNS Metastases Using Molecularly Targeted Agents and Immune Checkpoint Inhibitors. CNS drugs 32 (6) (2019)
Grainne M O'Kane, Éanna Ryan, Terri P McVeigh, Ben Creavin, John Mp Hyland, Diarmuid P O'Donoghue, Denise Keegan, Robert Geraghty, Delia Flannery, Carmel Nolan, Emily Donovan, Brian J Mehigan, Paul McCormick, Cian Muldoon, Michael Farrell, Conor Shields, Niall Mulligan, Michael John Kennedy, Andrew J Green, Desmond C Winter, Padraic MacMathuna, Kieran Sheahan, David J Gallagher
Screening for mismatch repair deficiency in colorectal cancer: data from three academic medical centers. Cancer medicine 6 (6) (2017)