Grant W Brown

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 35

Top Venues

G3 (Bethesda, Md.)

Nature cancer

Genetics

bioRxiv : the preprint server for biology

University of Toronto

University of California Los Angeles (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Toronto

Canada

Professor :: Biochemistry

Education History

University of California Los Angeles

United States

PHD :: Molecular Biology

University of British Columbia

Canada

BSC :: Biochemistry

Publications

Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer 5 (6) (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer (2024)
Alexander R Leydon, Benjamin L R Downing, Janet Solano Sanchez, Raphael Loll-Krippleber, Nathan M Belliveau, Ricard A Rodriguez-Mias, Andrew Bauer, Isabella J Watson, Lena Bae, Judit Vill N, Grant W Brown, Jennifer L Nemhauser
A conserved function of corepressors is to nucleate assembly of the transcriptional preinitiation complex. bioRxiv : the preprint server for biology (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer 5 (6) (2024)
Alexander R Leydon, Benjamin L R Downing, Janet Solano Sanchez, Raphael Loll-Krippleber, Nathan M Belliveau, Ricard A Rodriguez-Mias, Andrew Bauer, Isabella J Watson, Lena Bae, Judit Vill N, Grant W Brown, Jennifer L Nemhauser
A conserved function of corepressors is to nucleate assembly of the transcriptional preinitiation complex. bioRxiv : the preprint server for biology (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer 5 (6) (2024)
Miguel Pacheco, Karole N D'Orazio, Laura N Lessen, Anthony J Veltri, Zachary Neiman, Raphael Loll-Krippleber, Grant W Brown, Rachel Green
Genetic screens in Saccharomyces cerevisiae identify a role for 40S ribosome recycling factors Tma20 and Tma22 in nonsense-mediated decay. G3 (Bethesda, Md.) 14 (3) (2024)
Grant W Brown
The cytidine deaminase APOBEC3C has unique sequence and genome feature preferences. Genetics 227 (4) (2024)
Miguel Pacheco, Karole N D'Orazio, Laura N Lessen, Anthony J Veltri, Zachary Neiman, Raphael Loll-Krippleber, Grant W Brown, Rachel Green
Genetic screens in Saccharomyces cerevisiae identify a role for 40S ribosome recycling factors Tma20/22 in nonsense mediated decay. G3 (Bethesda, Md.) (2024)
Grant W Brown
The cytidine deaminase APOBEC3C has unique sequence and genome feature preferences. Genetics (2024)
Tajinder Ubhi, Olga Zaslaver, Andrew T Quaile, Dennis Plenker, Pinjiang Cao, Nhu-An Pham, Angéla Békési, Gun-Ho Jang, Grainne M O'Kane, Faiyaz Notta, Jason Moffat, Julie M Wilson, Steven J Gallinger, Beáta G Vértessy, David A Tuveson, Hannes L Röst, Grant W Brown
Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature cancer (2024)
Miguel Pacheco, Karole N D'Orazio, Laura N Lessen, Anthony J Veltri, Zachary Neiman, Raphael Loll-Krippleber, Grant W Brown, Rachel Green
Genetic screens in Saccharomyces cerevisiae identify a role for 40S ribosome recycling factors Tma20 and Tma22 in nonsense-mediated decay. G3 (Bethesda, Md.) 14 (3) (2024)
Raphael Loll-Krippleber, Yangyang Kate Jiang, Grant W Brown
pSPObooster: A Plasmid System to Improve Sporulation Efficiency of Saccharomyces cerevisiae Lab Strains. Yeast (Chichester, England) (2024)
Alexander R Leydon, Benjamin L R Downing, Janet Solano Sanchez, Raphael Loll-Krippleber, Nathan M Belliveau, Ricard A Rodriguez-Mias, Andrew Bauer, Isabella J Watson, Lena Bae, Judit Vill N, Grant W Brown, Jennifer L Nemhauser
A conserved function of corepressors is to nucleate assembly of the transcriptional preinitiation complex. bioRxiv : the preprint server for biology (2024)
Brandon Ho, Ethan J Sanford, Raphael Loll-Krippleber, Nikko P Torres, Marcus Bustamante Smolka, Grant W Brown
Mec1-independent activation of the Rad53 checkpoint kinase revealed by quantitative analysis of protein localization dynamics. eLife 12 (2023)
Siobhan O'Brien, Tajinder Ubhi, Lucie M Wolf, Krishna Gandhi, Sichun Lin, Naz Chaudary, Neesha C Dhani, Michael F Milosevic, Grant W Brown, Stephane Angers
FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe. Cancer research communications (2023)
Anthony J Veltri, Karole N D'Orazio, Laura N Lessen, Raphael Loll-Krippleber, Grant W Brown, Rachel Green
Distinct elongation stalls during translation are linked with distinct pathways for mRNA degradation. eLife 11 (2022)
Shinsuke Ohnuki, Itsuki Ogawa, Kaori Itto-Nakama, Fachuang Lu, Ashish Ranjan, Mehdi Kabbage, Abraham Abera Gebre, Masao Yamashita, Sheena C Li, Yoko Yashiroda, Satoshi Yoshida, Takeo Usui, Jeff S Piotrowski, Brenda J Andrews, Charles Boone, Grant W Brown, John Ralph, Yoshikazu Ohya
High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds. NPJ systems biology and applications 8 (1) (2022)
Matthew D Berg, Yanrui Zhu, Raphaël Loll-Krippleber, Bryan-Joseph San Luis, Julie Genereaux, Charles Boone, Judit Vill N, Grant W Brown, Christopher J Brandl
Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG. G3 (Bethesda, Md.) 12 (7) (2022)
Natalie A Lamb, Jonathan E Bard, Raphael Loll-Krippleber, Grant W Brown, Jennifer A Surtees
Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes. Genetics 221 (4) (2022)
Matthew D Berg, Yanrui Zhu, Bianca Y Ruiz, Raphaël Loll-Krippleber, Joshua Isaacson, Bryan-Joseph San Luis, Julie Genereaux, Charles Boone, Judit Villén, Grant W Brown, Christopher J Brandl
The amino acid substitution affects cellular response to mistranslation. G3 (Bethesda, Md.) 11 (10) (2021)
Grant W Brown, Brenda J Andrews
Setting molecular traps in yeast for identification of anticancer drug targets. Proceedings of the National Academy of Sciences of the United States of America 118 (18) (2021)
Matthew D Berg, Yanrui Zhu, Joshua Isaacson, Julie Genereaux, Raphaël Loll-Krippleber, Grant W Brown, Christopher J Brandl
Chemical-Genetic Interactions with the Proline Analog L-Azetidine-2-Carboxylic Acid in Saccharomyces cerevisiae. G3 (Bethesda, Md.) 10 (12) (2020)
Daniele Novarina, Ridhdhi Desai, Jessica A Vaisica, Jiongwen Ou, Mohammed Bellaoui, Grant W Brown, Michael Chang
A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae. G3 (Bethesda, Md.) 10 (6) (2020)
Lukas Tamayo-Orrego, David Gallo, Frédéric Racicot, Amandine Bemmo, Sushmetha Mohan, Brandon Ho, Samer Salameh, Trang Hoang, Andrew P Jackson, Grant W Brown, Frédéric Charron
Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma. Nature cancer 1 (8) (2020)
David Gallo, Grant W Brown
Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer. Critical reviews in biochemistry and molecular biology 54 (3) (2019)
Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N Koch, Carles Pons, Andrius J Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy A Caudy, Daniel I Bolnick, Grant W Brown, Brenda J Andrews, Charles Boone, Chad L Myers
Systematic analysis of complex genetic interactions. Science (New York, N.Y.) 360 (6386) (2018)
Tina L Sing, Minnie P Hung, Shinsuke Ohnuki, Godai Suzuki, Bryan-Joseph San Luis, Melainia McClain, Jay R Uhruh, Zulin Yu, Jiongwen Ou, Jesse Marshall-Sheppard, Won-Ki Huh, Michael Costanzo, Charles Boone, Yoshikazu Ohya, Sue L Jaspersen, Grant W Brown
The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion. The Journal of cell biology 217 (7) (2018)
Jeff S Piotrowski, Sheena C Li, Raamesh Deshpande, Scott W Simpkins, Justin Nelson, Yoko Yashiroda, Jacqueline M Barber, Hamid Safizadeh, Erin Wilson, Hiroki Okada, Abraham A Gebre, Karen Kubo, Nikko P Torres, Marissa A LeBlanc, Kerry Andrusiak, Reika Okamoto, Mami Yoshimura, Eva DeRango-Adem, Jolanda van Leeuwen, Katsuhiko Shirahige, Anastasia Baryshnikova, Grant W Brown, Hiroyuki Hirano, Michael Costanzo, Brenda Andrews, Yoshikazu Ohya, Hiroyuki Osada, Minoru Yoshida, Chad L Myers, Charles Boone
Functional annotation of chemical libraries across diverse biological processes. Nature chemical biology 13 (9) (2017)
Cristina Ramos-Pérez, Jessel Ayra-Plasencia, Emiliano Matos-Perdomo, Michael Lisby, Grant W Brown, Félix Machín
Genome-Scale Genetic Interactions and Cell Imaging Confirm Cytokinesis as Deleterious to Transient Topoisomerase II Deficiency in Saccharomyces cerevisiae. G3 (Bethesda, Md.) 7 (10) (2017)
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia, Farhia Kabeer, Daniel Lai, Priscilla Soriano, Judit Banáth, Derek S Chiu, Damian Yap, Daniel D Le, Frank B Ye, Anni Zhang, Kelsie Thu, John Soong, Shu-Chuan Lin, Angela Hsin Chin Tsai, Tomo Osako, Teresa Algara, Darren N Saunders, Jason Wong, Jian Xian, Marcel B Bally, James D Brenton, Grant W Brown, Sohrab P Shah, David Cescon, Tak W Mak, Carlos Caldas, Peter C Stirling, Phil Hieter, Shankar Balasubramanian, Samuel A J R Aparicio
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nature communications 8 (2017)
Raphael Loll-Krippleber, Grant W Brown
P-body proteins regulate transcriptional rewiring to promote DNA replication stress resistance. Nature communications 8 (1) (2017)
Askar Yimit, TaeHyung Kim, Ranjith P Anand, Sarah Meister, Jiongwen Ou, James E Haber, Zhaolei Zhang, Grant W Brown
MTE1 Functions with MPH1 in Double-Strand Break Repair. Genetics 203 (1) (2016)
Askar Yimit, Michael Riffle, Grant W Brown
Genetic Regulation of Dna2 Localization During the DNA Damage Response. G3 (Bethesda, Md.) 5 (9) (2015)
Jason A Hendry, Guihong Tan, Jiongwen Ou, Charles Boone, Grant W Brown
Leveraging DNA damage response signaling to identify yeast genes controlling genome stability. G3 (Bethesda, Md.) 5 (5) (2015)

Grant W Brown.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Grant W Brown