Ho-Yin Edwin Chan (Ho Yin Edwin Chan, H Y Edwin Chan)

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 21

Top Venues

Nature communications

Aging cell

Biosensors

Proceedings of the National Academy of Sciences of the United States of America

The Chinese University of Hong Kong

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Chinese University of Hong Kong

Hong Kong

Professor :: School of Life Sciences

University of Pennsylvania

United States

Postdoctoral Scientist :: Biology

Education History

University of Cambridge

United Kingdom

PHD :: Genetics

The Chinese University of Hong Kong

Hong Kong

BSC :: Biochemistry

Publications

Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Ronald P Hart, Kin-Ming Kwan, Ho-Yin Edwin Chan, Kim Hei-Man Chow
Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons. Aging cell 22 (2) (2023)
Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Ronald P Hart, Kin-Ming Kwan, Ho-Yin Edwin Chan, Kim Hei-Man Chow
Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons. Aging cell (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Ronald P Hart, Kin-Ming Kwan, Ho-Yin Edwin Chan, Kim Hei-Man Chow
Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons. Aging cell 22 (2) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Ronald P Hart, Kin-Ming Kwan, Ho-Yin Edwin Chan, Kim Hei-Man Chow
Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons. Aging cell 22 (2) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Matthew Ho Yan Lau, Chun-Ho Wong, Ho-Yin Edwin Chan, Ho Yu Au-Yeung
Development of Fluorescent Turn-On Probes for CAG-RNA Repeats. Biosensors 12 (12) (2022)
Matthew Ho Yan Lau, Chun-Ho Wong, Ho-Yin Edwin Chan, Ho Yu Au-Yeung
Development of Fluorescent Turn-On Probes for CAG-RNA Repeats. Biosensors 12 (12) (2022)
Matthew Ho Yan Lau, Chun-Ho Wong, Ho-Yin Edwin Chan, Ho Yu Au-Yeung
Development of Fluorescent Turn-On Probes for CAG-RNA Repeats. Biosensors 12 (12) (2022)
Pan P Li, Roumita Moulick, Hongxuan Feng, Xin Sun, Nicolas Arbez, Jing Jin, Leonard O Marque, Erin Hedglen, Ho-Yin Edwin Chan, Christopher A Ross, Stefan M Pulst, Russell L Margolis, Sarah Woodson, Dobrila D Rudnicki
RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2. Movement disorders : official journal of the Movement Disorder Society 36 (11) (2021)
Zhefan Stephen Chen, Xiaoying Huang, Kevin Talbot, Ho-Yin Edwin Chan
A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3. Cell death & disease 12 (2) (2021)
Shaohong Peng, Pei Guo, Xiao Lin, Ying An, Kong Hung Sze, Matthew Ho Yan Lau, Zhefan Stephen Chen, Qianwen Wang, Wen Li, Jacquelyne Ka-Li Sun, Sum Yi Ma, Ting-Fung Chan, Kwok-Fai Lau, Jacky Chi Ki Ngo, Kin-Ming Kwan, Chun-Ho Wong, Sik Lok Lam, Steven C Zimmerman, Tiziano Tuccinardi, Zhong Zuo, Ho Yu Au-Yeung, Hei-Man Chow, Ho-Yin Edwin Chan
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
Ma Rie Kim, Teng Feng, Qian Zhang, Ho-Yin Edwin Chan, Ying Chau
Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles. Polymers 11 (2) (2019)
JuYeon Lee, Yugang Bai, Ullas V Chembazhi, Shaohong Peng, Kevin Yum, Long M Luu, Lauren D Hagler, Julio F Serrano, Ho-Yin Edwin Chan, Auinash Kalsotra, Steven C Zimmerman
Intrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1. Proceedings of the National Academy of Sciences of the United States of America 116 (18) (2019)
Zhefan Stephen Chen, Azaria Kam Yan Wong, Tat Cheung Cheng, Alex Chun Koon, Ho-Yin Edwin Chan
FipoQ/FBXO33, a Cullin-1-based ubiquitin ligase complex component modulates ubiquitination and solubility of polyglutamine disease protein. Journal of neurochemistry 149 (6) (2019)
Zhefan Stephen Chen, Li Li, Shaohong Peng, Francis M Chen, Qian Zhang, Ying An, Xiao Lin, Wen Li, Alex Chun Koon, Ting-Fung Chan, Kwok-Fai Lau, Jacky Chi Ki Ngo, Wing Tak Wong, Kin Ming Kwan, Ho-Yin Edwin Chan
Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models. EMBO reports 19 (9) (2018)
Huiling Hong, Alex Chun Koon, Zhefan Stephen Chen, Yuming Wei, Ying An, Wen Li, Matthew Ho Yan Lau, Kwok-Fai Lau, Jacky Chi Ki Ngo, Chun-Ho Wong, Ho Yu Au-Yeung, Steven C Zimmerman, Ho-Yin Edwin Chan
AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models. The Journal of biological chemistry 294 (8) (2018)
Alex Chun Koon, Zhefan Stephen Chen, Shaohong Peng, Joyce Man See Fung, Xiaoman Zhang, Kayly M Lembke, Josh H K Chow, C Andrew Frank, Liwen Jiang, Kwok-Fai Lau, Ho-Yin Edwin Chan
Drosophila Exo70 Is Essential for Neurite Extension and Survival under Thermal Stress. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (37) (2018)
Allen Chi Shing Yu, Anne Yin-Yan Chan, Wing Chi Au, Yun Shen, Ting Fung Chan, Ho-Yin Edwin Chan
Whole-genome sequencing of two probands with hereditary spastic paraplegia reveals novel splice-donor region variant and known pathogenic variant in SPG11. Cold Spring Harbor molecular case studies 2 (6) (2017)

Ho-Yin Edwin Chan.css-eqlu8i{font-size:small;padding-left:4px;} (Ho Yin Edwin Chan, H Y Edwin Chan)

Publication Activity (10 Years)

Top Topics

Top Venues

Ho-Yin Edwin Chan (Ho Yin Edwin Chan, H Y Edwin Chan)