Ruxandra Dafinca

Publication Activity (10 Years)

Years Active: 2021-2023
Publications (10 Years): 7

Top Topics

Amyotrophic Lateral Sclerosis

Lipopolysaccharide Induced

Top Venues

Nature communications

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Björn Friedhelm Vahsen, Sumedha Nalluru, Georgia R Morgan, Lucy Farrimond, Emily Carroll, Yinyan Xu, Kaitlyn M L Cramb, Benazir Amein, Jakub Scaber, Antigoni Katsikoudi, Ana Candalija, Mireia Carcolé, Ruxandra Dafinca, Adrian M Isaacs, Richard Wade-Martins, Elizabeth Gray, Matthew C Kiernan, Sally A Cowley, Kevin Talbot
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Junli Gao, Quinlan T Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N Coyne, Ritika Punathil, Bong Gu Kang, Morgan Dasovich, Austin M Veire, Mariely DeJesus Hernandez, Shuaichen Liu, Zheng Shi, Ruxandra Dafinca, Elise Fouquerel, Kevin Talbot, Tae-In Kam, Yong-Jie Zhang, Gourisankar Ghosh, Leonard Petrucelli, Marka van Blitterswijk, Lin Guo, Ted M Dawson, Valina L Dawson, Anthony K L Leung, Thomas E Lloyd, Tania F Gendron, Jeffrey D Rothstein, Ke Zhang
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins. Science translational medicine 14 (662) (2022)
Topaz Altman, Ariel Ionescu, Amjad Ibraheem, Dominik Priesmann, Tal Gradus-Pery, Luba Farberov, Gayster Alexandra, Natalia Shelestovich, Ruxandra Dafinca, Noam Shomron, Florence Rage, Kevin Talbot, Michael E Ward, Amir Dori, Marcus Krueger, Eran Perlson
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins. Nature communications 12 (1) (2021)