Kevin Talbot (K Talbot)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 49

Top Venues

Nature communications

Brain communications

Disease models & mechanisms

Journal of neurology, neurosurgery, and psychiatry

Oxford University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Oxford University May 01 2006

United Kingdom

Professor :: Nuffield Department of Clinical Neurosciences

Publications

Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast
An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner. Disease models & mechanisms 17 (5) (2024)
Michael Trubshaw, Chetan Gohil, Katie Yoganathan, Oliver Kohl, Evan Edmond, Malcolm Proudfoot, Alexander Guy Thompson, Kevin Talbot, Charlotte J Stagg, Anna C Nobre, Mark Woolrich, Matthew C Kiernan
The cortical neurophysiological signature of amyotrophic lateral sclerosis. Brain communications 6 (3) (2024)
Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast
The ALS-associated TDP-43M337V mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner. Disease models & mechanisms (2024)
Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast
An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner. Disease models & mechanisms 17 (5) (2024)
Michael Trubshaw, Chetan Gohil, Katie Yoganathan, Oliver Kohl, Evan Edmond, Malcolm Proudfoot, Alexander Guy Thompson, Kevin Talbot, Charlotte J Stagg, Anna C Nobre, Mark Woolrich, Matthew C Kiernan
The cortical neurophysiological signature of amyotrophic lateral sclerosis. Brain communications 6 (3) (2024)
Lara M Nikel, Kevin Talbot, Björn Friedhelm Vahsen
Recent insights from human induced pluripotent stem cell models into the role of microglia in amyotrophic lateral sclerosis. BioEssays : news and reviews in molecular, cellular and developmental biology (2024)
Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast
An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner. Disease models & mechanisms 17 (5) (2024)
Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast
An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner. Disease models & mechanisms 17 (5) (2024)
Lara M Nikel, Kevin Talbot, Björn Friedhelm Vahsen
Recent insights from human induced pluripotent stem cell models into the role of microglia in amyotrophic lateral sclerosis. BioEssays : news and reviews in molecular, cellular and developmental biology 46 (7) (2024)
Raph Goldacre, Michael Trubshaw, Eva J A Morris, Kevin Talbot, Michael J Goldacre, Alexander Guy Thompson, Matthew C Kiernan
Venous thromboembolism risk in amyotrophic lateral sclerosis: a hospital record-linkage study. Journal of neurology, neurosurgery, and psychiatry (2024)
Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast
An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner. Disease models & mechanisms 17 (5) (2024)
Renata Vieira de Sá, Emma Sudria-Lopez, Marta Cañizares Luna, Oliver Harschnitz, Dianne M A van den Heuvel, Sandra Kling, Danielle Vonk, Henk-Jan Westeneng, Henk Karst, Lauri Bloemenkamp, Suzy Varderidou-Minasian, Domino K Schlegel, Mayte Mars, Mark H Broekhoven, Nicky C H van Kronenburg, Youri Adolfs, Vamshidhar R Vangoor, Rianne de Jongh, Tijana Ljubikj, Lianne Peeters, Sabine Seeler, Enric Mocholi, Onur Basak, David Gordon, Fabrizio Giuliani, Tessa Verhoeff, Giel Korsten, Teresa Calafat Pla, Morten T Venø, Jørgen Kjems, Kevin Talbot, Michael A Van Es, Jan Herman Veldink, Leonard H van den Berg, Pavol Zelina, Ronald Jeroen Pasterkamp
ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes. Nature communications 15 (1) (2024)
Michael Trubshaw, Chetan Gohil, Katie Yoganathan, Oliver Kohl, Evan Edmond, Malcolm Proudfoot, Alexander Guy Thompson, Kevin Talbot, Charlotte J Stagg, Anna C Nobre, Mark Woolrich, Matthew C Kiernan
The cortical neurophysiological signature of amyotrophic lateral sclerosis. Brain communications 6 (3) (2024)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Anna J Kordala, Jessica Stoodley, Nina Ahlskog, Muhammad Hanifi, Antonio Garcia-Guerra, Amarjit Bhomra, Wooi Fang Lim, Lyndsay M Murray, Kevin Talbot, Suzan M Hammond, Matthew Ja Wood, Carlo Rinaldi
PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice. EMBO molecular medicine (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Jennifer C Davies, Thanuja Dharmadasa, Alexander Guy Thompson, Evan C Edmond, Katie Yoganathan, Jiali Gao, Kevin Talbot, Matthew C Kiernan
Limited value of serum neurofilament light chain in diagnosing amyotrophic lateral sclerosis. Brain communications 5 (3) (2023)
Eleni Christoforidou, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast
Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43. Amyotrophic lateral sclerosis & frontotemporal degeneration (2023)
Björn Friedhelm Vahsen, Sumedha Nalluru, Georgia R Morgan, Lucy Farrimond, Emily Carroll, Yinyan Xu, Kaitlyn M L Cramb, Benazir Amein, Jakub Scaber, Antigoni Katsikoudi, Ana Candalija, Mireia Carcolé, Ruxandra Dafinca, Adrian M Isaacs, Richard Wade-Martins, Elizabeth Gray, Matthew C Kiernan, Sally A Cowley, Kevin Talbot
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9. Nature communications 14 (1) (2023)
Alexander Guy Thompson, Rachael Marsden, Kevin Talbot, Matthew C Kiernan
Primary care blood tests show lipid profile changes in pre-symptomatic amyotrophic lateral sclerosis. Brain communications 5 (4) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Greig Joilin, Elizabeth Gray, Alexander Guy Thompson, Kevin Talbot, P Nigel Leigh, Sarah F Newbury, Matthew C Kiernan, Majid Hafezparast
Profiling non-coding RNA expression in cerebrospinal fluid of amyotrophic lateral sclerosis patients. Annals of medicine 54 (1) (2022)
Alicia Dubinski, Myriam Gagné, Sarah Peyrard, David Gordon, Kevin Talbot, Christine Vande Velde
Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice. Human molecular genetics (2022)
Alexander Guy Thompson, Elizabeth Gray, Nick Verber, Yoana Bobeva, Vittoria Lombardi, Stephanie R Shepheard, Ozlem Yildiz, Emily Feneberg, Lucy Farrimond, Thanuja Dharmadasa, Pamela Gray, Evan C Edmond, Jakub Scaber, Delia Gagliardi, Janine Kirby, Thomas M Jenkins, Pietro Fratta, Christopher J McDermott, Sanjay G Manohar, Kevin Talbot, Andrea Malaspina, Pamela J Shaw, Matthew C Kiernan
Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain. Brain communications 4 (1) (2022)
Lucy Farrimond, Kevin Talbot
A case of SOD1 deficiency: implications for clinical trials. Brain : a journal of neurology 145 (3) (2022)
Puja R Mehta, Alfredo Iacoangeli, Sarah Opie-Martin, Joke J F A van Vugt, Ahmad Al Khleifat, Andrea Bredin, Lynn Ossher, Peter M Andersen, Orla Hardiman, Arpan R Mehta, Pietro Fratta, Kevin Talbot, null null, Ammar Al Chalabi
The impact of age on genetic testing decisions in amyotrophic lateral sclerosis. Brain : a journal of neurology (2022)
Junli Gao, Quinlan T Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N Coyne, Ritika Punathil, Bong Gu Kang, Morgan Dasovich, Austin M Veire, Mariely DeJesus Hernandez, Shuaichen Liu, Zheng Shi, Ruxandra Dafinca, Elise Fouquerel, Kevin Talbot, Tae-In Kam, Yong-Jie Zhang, Gourisankar Ghosh, Leonard Petrucelli, Marka van Blitterswijk, Lin Guo, Ted M Dawson, Valina L Dawson, Anthony K L Leung, Thomas E Lloyd, Tania F Gendron, Jeffrey D Rothstein, Ke Zhang
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins. Science translational medicine 14 (662) (2022)
Emily Feneberg, Philip D Charles, Mattéa J Finelli, Connor Scott, Benedikt Mathias Kessler, Roman Fischer, Olaf Ansorge, Elizabeth Gray, Kevin Talbot, Matthew C Kiernan
Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP. Brain pathology (Zurich, Switzerland) 31 (4) (2021)
Matthew Nolan, Paola Barbagallo, Matthew C Kiernan, Michael John Keogh, Patrick F Chinnery, Kevin Talbot, Olaf Ansorge
Isolated homozygous R217X OPTN mutation causes knock-out of functional C-terminal optineurin domains and associated oligodendrogliopathy-dominant ALS-TDP. Journal of neurology, neurosurgery, and psychiatry 92 (9) (2021)
Björn Friedhelm Vahsen, Elizabeth Gray, Alexander Guy Thompson, Olaf Ansorge, Daniel Clive Anthony, Sally A Cowley, Kevin Talbot, Matthew C Kiernan
Non-neuronal cells in amyotrophic lateral sclerosis - from pathogenesis to biomarkers. Nature reviews. Neurology 17 (6) (2021)
Zhefan Stephen Chen, Xiaoying Huang, Kevin Talbot, Ho-Yin Edwin Chan
A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3. Cell death & disease 12 (2) (2021)
Topaz Altman, Ariel Ionescu, Amjad Ibraheem, Dominik Priesmann, Tal Gradus-Pery, Luba Farberov, Gayster Alexandra, Natalia Shelestovich, Ruxandra Dafinca, Noam Shomron, Florence Rage, Kevin Talbot, Michael E Ward, Amir Dori, Marcus Krueger, Eran Perlson
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins. Nature communications 12 (1) (2021)
Alexander Guy Thompson, Kevin Talbot, Matthew C Kiernan
Higher blood high density lipoprotein and apolipoprotein A1 levels are associated with reduced risk of developing amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry (2021)
Mireia Herrando-Grabulosa, Caty Casas, Kevin Talbot, José Aguilera
Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease. Toxins 12 (10) (2020)
Kevin Talbot, Matthew John Andrew Wood
Wrangling RNA: Antisense oligonucleotides for neurological disorders. Science translational medicine 11 (511) (2020)
Carolyn Anne Young, Roger Mills, Ammar Al-Chalabi, Georgina Burke, Siddharthan Chandran, David J Dick, John Ealing, Clemens O Hanemann, Timothy Harrower, Christopher J Mcdermott, Tahir Majeed, Ashwin Pinto, Kevin Talbot, Jannette Walsh, Timothy L Williams, Alan Tennant, null null
Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF. Amyotrophic lateral sclerosis & frontotemporal degeneration (2020)
Madeline L Kelly, Arseniy Lavrov, Luis Garcia-Gancedo, Jim Parr, Robert Hart, Theresa Chiwera, Christopher E Shaw, Ammar Al Chalabi, Rachael Marsden, Matthew C Kiernan, Kevin Talbot
The use of biotelemetry to explore disease progression markers in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration 21 (7-8) (2020)
Greig Joilin, Elizabeth Gray, Alexander Guy Thompson, Yoana Bobeva, Kevin Talbot, Jochen Weishaupt, Albert Ludolph, Andrea Malaspina, P Nigel Leigh, Sarah F Newbury, Martin R Turner, Majid Hafezparast
Identification of a potential non-coding RNA biomarker signature for amyotrophic lateral sclerosis. Brain communications 2 (1) (2020)
Emily Feneberg, Matthew C Kiernan, Olaf Ansorge, Kevin Talbot
Amyotrophic lateral sclerosis with a heterozygous D91A SOD1 variant and classical ALS-TDP neuropathology. Neurology 95 (13) (2020)
Matthew C Kiernan, Steve Vucic, Kevin Talbot, Christopher J McDermott, Orla Hardiman, Jeremy M Shefner, Ammar Al Chalabi, William Huynh, Merit Cudkowicz, Paul Talman, Leonard H Van den Berg, Thanuja Dharmadasa, Paul Wicks, Claire Reilly, Matthew C Kiernan
Improving clinical trial outcomes in amyotrophic lateral sclerosis. Nature reviews. Neurology 17 (2) (2020)
Kevin Talbot
Amyotrophic Lateral Sclerosis: network vulnerability and monosynaptic connections. Journal of neurology, neurosurgery, and psychiatry 91 (9) (2020)
Luis Garcia-Gancedo, Madeline L Kelly, Arseniy Lavrov, Jim Parr, Robert Hart, Rachael Marsden, Matthew C Kiernan, Kevin Talbot, Theresa Chiwera, Christopher E Shaw, Ammar Al Chalabi
Objectively Monitoring Amyotrophic Lateral Sclerosis Patient Symptoms During Clinical Trials With Sensors: Observational Study. JMIR mHealth and uHealth 7 (12) (2019)
Kevin Talbot, Emily Feneberg, Jakub Scaber, Alexander G Thompson, Martin R Turner
Amyotrophic lateral sclerosis: the complex path to precision medicine. Journal of neurology 265 (10) (2018)
Melissa Bowerman, Catherina G Becker, Rafael J Yáñez-Muñoz, Ke Ning, Matthew J A Wood, Thomas H Gillingwater, Kevin Talbot, null null
Therapeutic strategies for spinal muscular atrophy: SMN and beyond. Disease models & mechanisms 10 (8) (2018)
Bradley N Smith, Simon D Topp, Claudia Fallini, Hideki Shibata, Han-Jou Chen, Claire Troakes, Andrew King, Nicola Ticozzi, Kevin P Kenna, Athina Soragia-Gkazi, Jack W Miller, Akane Sato, Diana Marques Dias, Maryangel Jeon, Caroline Vance, Chun Hao Wong, Martina de Majo, Wejdan Kattuah, Jacqueline C Mitchell, Emma L Scotter, Nicholas W Parkin, Peter C Sapp, Matthew Nolan, Peter J Nestor, Michael Simpson, Michael Weale, Monkel Lek, Frank Baas, J M Vianney de Jong, Anneloor L M A Ten Asbroek, Alberto Garcia Redondo, Jesús Esteban-Pérez, Cinzia Tiloca, Federico Verde, Stefano Duga, P Nigel Leigh, Hardev Pall, Karen E Morrison, Ammar Al-Chalabi, Christopher E Shaw, Janine Kirby, Matthew C Kiernan, Kevin Talbot, Orla Hardiman, Jonathan D Glass, Jacqueline S de Belleroche, Masatoshi Maki, Stephen E Moss, Christopher Miller, Cinzia Gellera, Antonia Ratti, Safa Al-Sarraj, Robert H Brown, Vincenzo Silani, John E Landers, Christopher E Shaw
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis. Science translational medicine 9 (388) (2018)
Kevin Talbot, E F Tizzano
The clinical landscape for SMA in a new therapeutic era. Gene therapy 24 (9) (2017)
James N Sleigh, John M Dawes, Steven J West, Na Wei, Emily L Spaulding, Adriana Gómez-Martín, Qian Zhang, Robert W Burgess, M Zameel Cader, Kevin Talbot, Xiang-Lei Yang, David L Bennett, Giampietro Schiavo
Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations. Proceedings of the National Academy of Sciences of the United States of America 114 (16) (2017)
Kevin P Kenna, Perry T C van Doormaal, Annelot M Dekker, Nicola Ticozzi, Brendan J Kenna, Frank P Diekstra, Wouter van Rheenen, Kristel R van Eijk, Ashley R Jones, Pamela Keagle, Aleksey Shatunov, William Sproviero, Bradley N Smith, Michael A van Es, Simon D Topp, Aoife Kenna, Jack W Miller, Claudia Fallini, Cinzia Tiloca, Russell L McLaughlin, Caroline Vance, Claire Troakes, Claudia Colombrita, Gabriele Mora, Andrea Calvo, Federico Verde, Safa Al-Sarraj, Andrew King, Daniela Calini, Jacqueline de Belleroche, Frank Baas, Anneke J van der Kooi, Marianne de Visser, Anneloor L M A Ten Asbroek, Peter C Sapp, Diane McKenna-Yasek, Meraida Polak, Seneshaw Asress, José Luis Muñoz-Blanco, Tim M Strom, Thomas Meitinger, Karen E Morrison, null null, Giuseppe Lauria, Kelly Louise Williams, P Nigel Leigh, Garth A Nicholson, Ian P Blair, Claire S Leblond, Patrick A Dion, Guy A Rouleau, Hardev Pall, Pamela J Shaw, Matthew C Kiernan, Kevin Talbot, Franco Taroni, Kevin B Boylan, Marka Van Blitterswijk, Rosa Rademakers, Jesús Esteban-Pérez, Alberto García-Redondo, Phillip Van Damme, Wim Robberecht, Adriano Chio, Cinzia Gellera, Carsten Drepper, Michael Sendtner, Antonia Ratti, Jonathan D Glass, Jesús S Mora, Nazli A Basak, Orla Hardiman, Albert C Ludolph, Peter M Andersen, Jochen H Weishaupt, Robert H Brown, Ammar Al-Chalabi, Vincenzo Silani, Christopher E Shaw, Leonard H van den Berg, Jan H Veldink, John E Landers
NEK1 variants confer susceptibility to amyotrophic lateral sclerosis. Nature genetics 48 (9) (2016)

Kevin Talbot.css-eqlu8i{font-size:small;padding-left:4px;} (K Talbot)

Publication Activity (10 Years)

Top Topics

Top Venues

Kevin Talbot (K Talbot)