Tiziano Tuccinardi

Scopus Author ID ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 74

Top Venues

Molecules (Basel, Switzerland)

Journal of enzyme inhibition and medicinal chemistry

Journal of medicinal chemistry

International journal of molecular sciences

Temple University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Temple University Jun 01 2016

United States

Adjunct Associate Professor :: Department of Biology

University of Pisa Apr 01 2015

Italy

Associate Professor :: Department of Pharmacy

Publications

Giulia Bononi, Chiara Lonzi, Tiziano Tuccinardi, Filippo Minutolo, Carlotta Granchi
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review. Molecules (Basel, Switzerland) 29 (9) (2024)
Giulia Bononi, Chiara Lonzi, Tiziano Tuccinardi, Filippo Minutolo, Carlotta Granchi
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review. Molecules (Basel, Switzerland) 29 (9) (2024)
Marta Alberti, Giulio Poli, Luca Broggini, Stefano Sainas, Menico Rizzi, Donatella Boschi, Davide M Ferraris, Elena Martino, Stefano Ricagno, Tiziano Tuccinardi, Marco Lucio Lolli, Riccardo Miggiano
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent. Acta crystallographica. Section D, Structural biology 80 (Pt 6) (2024)
Marta Alberti, Giulio Poli, Luca Broggini, Stefano Sainas, Menico Rizzi, Donatella Boschi, Davide M Ferraris, Elena Martino, Stefano Ricagno, Tiziano Tuccinardi, Marco Lucio Lolli, Riccardo Miggiano
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent. Acta crystallographica. Section D, Structural biology 80 (Pt 6) (2024)
Marta Alberti, Giulio Poli, Luca Broggini, Stefano Sainas, Menico Rizzi, Donatella Boschi, Davide M Ferraris, Elena Martino, Stefano Ricagno, Tiziano Tuccinardi, Marco Lucio Lolli, Riccardo Miggiano
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent. Acta crystallographica. Section D, Structural biology (2024)
Giulia Bononi, Chiara Lonzi, Tiziano Tuccinardi, Filippo Minutolo, Carlotta Granchi
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review. Molecules (Basel, Switzerland) 29 (9) (2024)
Giulio Poli, Gian Carlo Demontis, Andrea Sodi, Alessandro Saba, Stanislao Rizzo, Marco Macchia, Tiziano Tuccinardi
An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of h RPE65. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Emanuela Berrino, Simone Carradori, Fabrizio Carta, Francesco Melfi, Marialucia Gallorini, Giulio Poli, Tiziano Tuccinardi, José G Fernández-Bolaños, Óscar López, Jacobus P Petzer, Anél Petzer, Paolo Guglielmi, Daniela Secci, Claudiu T Supuran
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration. Antioxidants (Basel, Switzerland) 12 (12) (2023)
Giulio Poli, Gian Carlo Demontis, Andrea Sodi, Alessandro Saba, Stanislao Rizzo, Marco Macchia, Tiziano Tuccinardi
An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of h RPE65. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Salvatore Galati, Miriana Di Stefano, Marco Macchia, Giulio Poli, Tiziano Tuccinardi
MolBook UNIPI─Create, Manage, Analyze, and Share Your Chemical Data for Free. Journal of chemical information and modeling (2023)
Salvatore Galati, Miriana Di Stefano, Simone Bertini, Carlotta Granchi, Antonio Giordano, Francesca Gado, Marco Macchia, Tiziano Tuccinardi, Giulio Poli
Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening. International journal of molecular sciences 24 (24) (2023)
Giulio Poli, Gian Carlo Demontis, Andrea Sodi, Alessandro Saba, Stanislao Rizzo, Marco Macchia, Tiziano Tuccinardi
An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of h RPE65. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Salvatore Galati, Miriana Di Stefano, Simone Bertini, Carlotta Granchi, Antonio Giordano, Francesca Gado, Marco Macchia, Tiziano Tuccinardi, Giulio Poli
Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening. International journal of molecular sciences 24 (24) (2023)
Miriana Di Stefano, Salvatore Galati, Lisa Piazza, Carlotta Granchi, Simone Mancini, Filippo Fratini, Marco Macchia, Giulio Poli, Tiziano Tuccinardi
VenomPred 2.0: A Novel In Silico Platform for an Extended and Human Interpretable Toxicological Profiling of Small Molecules. Journal of chemical information and modeling (2023)
Emanuela Berrino, Simone Carradori, Fabrizio Carta, Francesco Melfi, Marialucia Gallorini, Giulio Poli, Tiziano Tuccinardi, José G Fernández-Bolaños, Óscar López, Jacobus P Petzer, Anél Petzer, Paolo Guglielmi, Daniela Secci, Claudiu T Supuran
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration. Antioxidants (Basel, Switzerland) 12 (12) (2023)
Giulia Bononi, Miriana Di Stefano, Giulio Poli, Gabriella Ortore, Philip Meier, Francesca Masetto, Isabella Caligiuri, Flavio Rizzolio, Marco Macchia, Andrea Chicca, Amir Avan, Elisa Giovannetti, Chiara Vagaggini, Annalaura Brai, Elena Dreassi, Massimo Valoti, Filippo Minutolo, Carlotta Granchi, Jürg Gertsch, Tiziano Tuccinardi
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives. Journal of medicinal chemistry 65 (10) (2022)
Salvatore Santamaria, Frederic Buemi, Elisa Nuti, Doretta Cuffaro, Elena De Vita, Tiziano Tuccinardi, Armando Rossello, Steven Howell, Shahid Mehmood, Ambrosius P Snijders, Rens de Groot
Development of a fluorogenic ADAMTS-7 substrate. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2022)
Stefano Sainas, Marta Giorgis, Paola Circosta, Giulio Poli, Marta Alberti, Alice Passoni, Valentina Gaidano, Agnese C Pippione, Nicoletta Vitale, Davide Bonanni, Barbara Rolando, Alessandro Cignetti, Cristina Ramondetti, Alessia Lanno, Davide M Ferraris, Barbara Canepa, Barbara Buccinnà, Marco Piccinini, Menico Rizzi, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Riccardo Miggiano, Tiziano Tuccinardi, Marco Lucio Lolli
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold: SAR of the Aryloxyaryl Moiety. Journal of medicinal chemistry 65 (19) (2022)
Francesco Balestri, Giulio Poli, Lucia Piazza, Mario Cappiello, Roberta Moschini, Giovanni Signore, Tiziano Tuccinardi, Umberto Mura, Antonella Del Corso
Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches. Biology 11 (9) (2022)
Giulio Poli, Miriana Di Stefano, Joan Arias Estevez, Filippo Minutolo, Carlotta Granchi, Antonio Giordano, Salvatore Parisi, Matteo Mauceri, Vincenzo Canzonieri, Marco Macchia, Isabella Caligiuri, Tiziano Tuccinardi, Flavio Rizzolio
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Costanza Ceni, Michael J Benko, Kawthar A Mohamed, Giulio Poli, Miriana Di Stefano, Tiziano Tuccinardi, Maria Digiacomo, Massimo Valoti, Robert B Laprairie, Marco Macchia, Simone Bertini
Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1 H )-One Scaffold. Pharmaceuticals (Basel, Switzerland) 15 (7) (2022)
Miriana Di Stefano, Salvatore Galati, Gabriella Ortore, Isabella Caligiuri, Flavio Rizzolio, Costanza Ceni, Simone Bertini, Giulia Bononi, Carlotta Granchi, Marco Macchia, Giulio Poli, Tiziano Tuccinardi
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors. International journal of molecular sciences 23 (18) (2022)
Salvatore Galati, Miriana Di Stefano, Elisa Martinelli, Marco Macchia, Adriano Martinelli, Giulio Poli, Tiziano Tuccinardi
VenomPred: A Machine Learning Based Platform for Molecular Toxicity Predictions. International journal of molecular sciences 23 (4) (2022)
Simone Carradori, Marialuigia Fantacuzzi, Alessandra Ammazzalorso, Andrea Ageli, Barbara De Filippis, Salvatore Galati, Anél Petzer, Jacobus P Petzer, Giulio Poli, Tiziano Tuccinardi, Mariangela Agamennone, Claudiu T Supuran
Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases? Molecules (Basel, Switzerland) 27 (22) (2022)
Giulia Bononi, Lorenzo Flori, Valentina Citi, Cecilia Acciai, Viviana Nocilla, Alma Martelli, Giulio Poli, Tiziano Tuccinardi, Carlotta Granchi, Lara Testai, Vincenzo Calderone, Filippo Minutolo
New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds. Pharmaceuticals (Basel, Switzerland) 15 (3) (2022)
Giulia Bononi, Valentina Citi, Margherita Lapillo, Alma Martelli, Giulio Poli, Tiziano Tuccinardi, Carlotta Granchi, Lara Testai, Vincenzo Calderone, Filippo Minutolo
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives. Molecules (Basel, Switzerland) 27 (19) (2022)
Giulio Poli, Ivana Barravecchia, Gian Carlo Demontis, Andrea Sodi, Alessandro Saba, Stanislao Rizzo, Marco Macchia, Tiziano Tuccinardi
Predicting potentially pathogenic effects of h RPE65 missense mutations: a computational strategy based on molecular dynamics simulations. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Salvatore Galati, Stefano Sainas, Marta Giorgis, Donatella Boschi, Marco L Lolli, Gabriella Ortore, Giulio Poli, Tiziano Tuccinardi
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study. Molecules (Basel, Switzerland) 27 (12) (2022)
Ali I M Ibrahim, Elisabet Batlle, Smarakan Sneha, Rafael Jiménez, Raquel Pequerul, Xavier Parés, Till Rüngeler, Vibhu Jha, Tiziano Tuccinardi, Maria Sadiq, Fiona Frame, Norman J Maitland, Jaume Farrés, Klaus Pors
Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. Journal of medicinal chemistry 65 (5) (2022)
Doretta Cuffaro, Caterina Camodeca, Tiziano Tuccinardi, Lidia Ciccone, Jörg W Bartsch, Tanja Kellermann, Lena Cook, Elisa Nuti, Armando Rossello
Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors. ACS medicinal chemistry letters 12 (11) (2021)
Ana Podolski-Renić, Jelena Dinic, Tijana Stanković, Ivanka Tsakovska, Ilza Pajeva, Tiziano Tuccinardi, Lorenzo Botta, Silvia Schenone, Milica Pesic
New Therapeutic Strategy for Overcoming Multidrug Resistance in Cancer Cells with Pyrazolo[3,4-d]pyrimidine Tyrosine Kinase Inhibitors. Cancers 13 (21) (2021)
Ashraf N Abdalla, Miriana Di Stefano, Giulio Poli, Tiziano Tuccinardi, Ammar Bader, Antonio Vassallo, Mohamed E Abdallah, Mahmoud Zaki El-Readi, Bassem Refaat, Alanood S Algarni, Rizwan Ahmad, Hamad M Al Kahtani, Alaa A-M Abdel-Aziz, Adel S El-Azab, Aljawharah Alqathama
Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin. Molecules (Basel, Switzerland) 27 (1) (2021)
Salvatore Galati, Miriana Di Stefano, Elisa Martinelli, Giulio Poli, Tiziano Tuccinardi
Recent Advances in In Silico Target Fishing. Molecules (Basel, Switzerland) 26 (17) (2021)
Giulia Bononi, Tiziano Tuccinardi, Flavio Rizzolio, Carlotta Granchi
α/β-Hydrolase Domain (ABHD) Inhibitors as New Potential Therapeutic Options against Lipid-Related Diseases. Journal of medicinal chemistry 64 (14) (2021)
Kanwal Asif, Lorenzo Memeo, Stefano Palazzolo, Yahima Frión-Herrera, Salvatore Parisi, Isabella Caligiuri, Vincenzo Canzonieri, Carlotta Granchi, Tiziano Tuccinardi, Flavio Rizzolio
STARD3: A Prospective Target for Cancer Therapy. Cancers 13 (18) (2021)
Shaohong Peng, Pei Guo, Xiao Lin, Ying An, Kong Hung Sze, Matthew Ho Yan Lau, Zhefan Stephen Chen, Qianwen Wang, Wen Li, Jacquelyne Ka-Li Sun, Sum Yi Ma, Ting-Fung Chan, Kwok-Fai Lau, Jacky Chi Ki Ngo, Kin-Ming Kwan, Chun-Ho Wong, Sik Lok Lam, Steven C Zimmerman, Tiziano Tuccinardi, Zhong Zuo, Ho Yu Au-Yeung, Hei-Man Chow, Ho-Yin Edwin Chan
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
Tiziano Tuccinardi
What is the current value of MM/PBSA and MM/GBSA methods in drug discovery? Expert opinion on drug discovery 16 (11) (2021)
Stefano Palazzolo, Lorenzo Memeo, Mohamad Hadla, Fahriye Duzagac, Agostino Steffan, Tiziana Perin, Vincenzo Canzonieri, Tiziano Tuccinardi, Isabella Caligiuri, Flavio Rizzolio
Cancer Extracellular Vesicles: Next-Generation Diagnostic and Drug Delivery Nanotools. Cancers 12 (11) (2020)
Vibhu Jha, Marco Macchia, Tiziano Tuccinardi, Giulio Poli
Three-Dimensional Interactions Analysis of the Anticancer Target c-Src Kinase with Its Inhibitors. Cancers 12 (8) (2020)
Vibhu Jha, Salvatore Galati, Valerio Volpi, Lidia Ciccone, Filippo Minutolo, Flavio Rizzolio, Carlotta Granchi, Giulio Poli, Tiziano Tuccinardi
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study. Journal of biomolecular structure & dynamics 39 (11) (2020)
Matteo Mori, Giovanni Stelitano, Arianna Gelain, Elena Pini, Laurent Roberto Chiarelli, Jose Camilla Sammartino, Giulio Poli, Tiziano Tuccinardi, Giangiacomo Beretta, Alessio Porta, Marco Bellinzoni, Stefania Villa, Fiorella Meneghetti
Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design. Journal of medicinal chemistry 63 (13) (2020)
Giulia Bononi, Giulio Poli, Flavio Rizzolio, Tiziano Tuccinardi, Marco Macchia, Filippo Minutolo, Carlotta Granchi
An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present). Expert opinion on therapeutic patents 31 (2) (2020)
Melissa D'Ascenzio, Daniela Secci, Simone Carradori, Susi Zara, Paolo Guglielmi, Roberto Cirilli, Marco Pierini, Giulio Poli, Tiziano Tuccinardi, Andrea Angeli, Claudiu T Supuran
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors. Journal of medicinal chemistry 63 (5) (2020)
Giulio Poli, Carlotta Granchi, Flavio Rizzolio, Tiziano Tuccinardi
Application of MM-PBSA Methods in Virtual Screening. Molecules (Basel, Switzerland) 25 (8) (2020)
Angela Bisio, Anna M Schito, Francesca Pedrelli, Ombeline Danton, Jakob K Reinhardt, Giulio Poli, Tiziano Tuccinardi, Thomas Buergi, Francesco De Riccardis, Mauro Giacomini, Daniela Calzia, Isabella Panfoli, Gian Carlo Schito, Matthias Hamburger, Nunziatina De Tommasi
Antibacterial and ATP Synthesis Modulating Compounds from Salvia tingitana. Journal of natural products 83 (4) (2020)
Giulio Poli, Salvatore Galati, Adriano Martinelli, Claudiu T Supuran, Tiziano Tuccinardi
Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors. Journal of enzyme inhibition and medicinal chemistry 35 (1) (2020)
Vibhu Jha, Marzia Biagi, Valeria Spinelli, Miriana Di Stefano, Marco Macchia, Filippo Minutolo, Carlotta Granchi, Giulio Poli, Tiziano Tuccinardi
Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study. Molecules (Basel, Switzerland) 26 (1) (2020)
Simone Mancini, Filippo Fratini, Barbara Turchi, Mattioli Simona, Alessandro Dal Bosco, Tiziano Tuccinardi, Sanjin Nozic, Gisella Paci
Former Foodstuff Products in Tenebrio Molitor Rearing: Effects on Growth, Chemical Composition, Microbiological Load, and Antioxidant Status. Animals : an open access journal from MDPI 9 (8) (2019)
Giulio Poli, Margherita Lapillo, Vibhu Jha, Nayla Mouawad, Isabella Caligiuri, Marco Macchia, Filippo Minutolo, Flavio Rizzolio, Tiziano Tuccinardi, Carlotta Granchi
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Margherita Lapillo, Tiziano Tuccinardi, Adriano Martinelli, Marco Macchia, Antonio Giordano, Giulio Poli
Extensive Reliability Evaluation of Docking-Based Target-Fishing Strategies. International journal of molecular sciences 20 (5) (2019)
Samer Bayda, Muhammad Adeel, Tiziano Tuccinardi, Marco Cordani, Flavio Rizzolio
The History of Nanoscience and Nanotechnology: From Chemical-Physical Applications to Nanomedicine. Molecules (Basel, Switzerland) 25 (1) (2019)
Carlotta Granchi, Margherita Lapillo, Sandra Glasmacher, Giulia Bononi, Cristina Licari, Giulio Poli, Maguie El Boustani, Isabella Caligiuri, Flavio Rizzolio, Juerg Gertsch, Marco Macchia, Filippo Minutolo, Tiziano Tuccinardi, Andrea Chicca
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor. Journal of medicinal chemistry 62 (4) (2019)
Valentina Maggini, Marinella De Leo, Carlotta Granchi, Tiziano Tuccinardi, Alessio Mengoni, Eugenia Rosaria Gallo, Sauro Biffi, Renato Fani, Luisa Pistelli, Fabio Firenzuoli, Patrizia Bogani
The influence of Echinacea purpurea leaf microbiota on chicoric acid level. Scientific reports 9 (1) (2019)
Jean Jacques Vanden Eynde, Arduino Aleksander Mangoni, Jarkko Rautio, Jérôme Leprince, Yasu-Taka Azuma, Alfonso T García-Sosa, Christopher Hulme, Josef Jampilek, Rafik Karaman, Wei Li, Paula A C Gomes, Dimitra Hadjipavlou-Litina, Raffaele Capasso, Athina Geronikaki, Gennaro Chiappetta, Jean Marc Sabatier, Rino Ragno, Tiziano Tuccinardi, Andrea Trabocchi, Jean-Yves Winum, Francisco Javier Luque, Katalin Prokai-Tatrai, Mariana Spetea, Michael Gütschow, Ivan Kosalec, Catherine Guillou, Maria Helena Vasconcelos, George Kokotos, Giulio Rastelli, Maria Emília Sousa, Clementina Manera, Sandra Gemma, Stefano Mangani, Carlo Siciliano, Stefania Galdieroa, Hong Liu, Peter J H Scott, Cristóbal de Los Ríos, Luigi A Agrofoglio, Simona Collina, Rita C Guedes, Diego Muñoz-Torrero
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6. Molecules (Basel, Switzerland) 25 (1) (2019)
Arduino Aleksander Mangoni, Jean Jacques Vanden Eynde, Josef Jampilek, Dimitra Hadjipavlou-Litina, Hong Liu, Jóhannes Reynisson, Maria Emília Sousa, Paula A C Gomes, Katalin Prokai-Tatrai, Tiziano Tuccinardi, Jean Marc Sabatier, Francisco Javier Luque, Jarkko Rautio, Rafik Karaman, Maria Helena Vasconcelos, Sandra Gemma, Stefania Galdieroa, Christopher Hulme, Simona Collina, Michael Gütschow, George Kokotos, Carlo Siciliano, Raffaele Capasso, Luigi A Agrofoglio, Rino Ragno, Diego Muñoz-Torrero
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5. Molecules (Basel, Switzerland) 24 (13) (2019)
Mikhail Yu Krasavin, Mikhail Korsakov, Oksana Ronzhina, Tiziano Tuccinardi, Stanislav Kalinin, Muhammet Tanç, Claudiu T Supuran
Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases. Journal of enzyme inhibition and medicinal chemistry 32 (1) (2019)
Kerem Buran, Silvia Bua, Giulio Poli, F Esra Önen Bayram, Tiziano Tuccinardi, Claudiu T Supuran
Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII. International journal of molecular sciences 20 (5) (2019)
Laurent Roberto Chiarelli, Matteo Mori, Giangiacomo Beretta, Arianna Gelain, Elena Pini, Jose Camilla Sammartino, Giovanni Stelitano, Daniela Barlocco, Luca Costantino, Margherita Lapillo, Giulio Poli, Isabella Caligiuri, Flavio Rizzolio, Marco Bellinzoni, Tiziano Tuccinardi, Stefania Villa, Fiorella Meneghetti
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Francesco Balestri, Vito Barracco, Giovanni Renzone, Tiziano Tuccinardi, Christian Silvio Pomelli, Mario Cappiello, Giulia Marianetti, Rossella Rotondo, Fabio Bellina, Andrea Scaloni, Umberto Mura, Antonella Del Corso, Roberta Moschini
Stereoselectivity of Aldose Reductase in the Reduction of Glutathionyl-Hydroxynonanal Adduct. Antioxidants (Basel, Switzerland) 8 (10) (2019)
Felicia D'Andrea, Giulia Vagelli, Carlotta Granchi, Lorenzo Guazzelli, Tiziano Tuccinardi, Giulio Poli, Dalila Iacopini, Filippo Minutolo, Valeria Di Bussolo
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents. Molecules (Basel, Switzerland) 24 (19) (2019)
Sara Carpi, Beatrice Polini, Giulio Poli, Gabriela Alcantara Barata, Stefano Fogli, Antonella Romanini, Tiziano Tuccinardi, Graziano Guella, Francesco Paolo Frontini, Paola Nieri, Graziano Di Giuseppe
Anticancer Activity of Euplotin C, Isolated from the Marine Ciliate Euplotes crassus, Against Human Melanoma Cells. Marine drugs 16 (5) (2018)
Giulio Poli, Vibhu Jha, Adriano Martinelli, Claudiu T Supuran, Tiziano Tuccinardi
Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors. International journal of molecular sciences 19 (7) (2018)
Arduino Aleksander Mangoni, Tiziano Tuccinardi, Simona Collina, Jean Jacques Vanden Eynde, Diego Muñoz-Torrero, Rafik Karaman, Carlo Siciliano, Maria Emília Sousa, Katalin Prokai-Tatrai, Jarkko Rautio, Catherine Guillou, Michael Gütschow, Stefania Galdieroa, Hong Liu, Luigi A Agrofoglio, Jean Marc Sabatier, Christopher Hulme, George Kokotos, Qi-Dong You, Paula A C Gomes
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3. Molecules (Basel, Switzerland) 23 (7) (2018)
Arduino Aleksander Mangoni, Catherine Guillou, Jean Jacques Vanden Eynde, Christopher Hulme, Josef Jampilek, Wei Li, Katalin Prokai-Tatrai, Jarkko Rautio, Simona Collina, Tiziano Tuccinardi, Maria Emília Sousa, Jean Marc Sabatier, Stefania Galdieroa, Rafik Karaman, George Kokotos, Giangiacomo Torri, Francisco Javier Luque, Maria Helena Vasconcelos, Dimitra Hadjipavlou-Litina, Carlo Siciliano, Michael Gütschow, Rino Ragno, Paula A C Gomes, Luigi A Agrofoglio, Diego Muñoz-Torrero
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4. Molecules (Basel, Switzerland) 24 (1) (2018)
Francesca Gado, Lorenzo Di Cesare Mannelli, Elena Lucarini, Simone Bertini, Elena Cappelli, Maria Digiacomo, Lesley A Stevenson, Marco Macchia, Tiziano Tuccinardi, Carla Ghelardini, Roger G Pertwee, Clementina Manera
Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief. Journal of medicinal chemistry 62 (1) (2018)
Elena Pini, Giulio Poli, Tiziano Tuccinardi, Laurent Roberto Chiarelli, Matteo Mori, Arianna Gelain, Luca Costantino, Stefania Villa, Fiorella Meneghetti, Daniela Barlocco
New Chromane-Based Derivatives as Inhibitors of Mycobacterium tuberculosis Salicylate Synthase (MbtI): Preliminary Biological Evaluation and Molecular Modeling Studies. Molecules (Basel, Switzerland) 23 (7) (2018)
Giulio Poli, Margherita Lapillo, Carlotta Granchi, Jessica Caciolla, Nayla Mouawad, Isabella Caligiuri, Flavio Rizzolio, Thierry Langer, Filippo Minutolo, Tiziano Tuccinardi
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors. Journal of enzyme inhibition and medicinal chemistry 33 (1) (2018)
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Stefania Baraldi, Emanuela Ruggiero, Lucia De Stefano, Flavio Rizzolio, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Andrea Chicca, Margherita Lapillo, Juerg Gertsch, Clementina Manera, Marco Macchia, Adriano Martinelli, Carlotta Granchi, Filippo Minutolo, Tiziano Tuccinardi
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors. Journal of medicinal chemistry 61 (3) (2018)
Angela Bisio, Maria De Mieri, Luigi Milella, Anna M Schito, Anita Parricchi, Daniela Russo, Silvana Alfei, Margherita Lapillo, Tiziano Tuccinardi, Matthias Hamburger, Nunziatina De Tommasi
Antibacterial and Hypoglycemic Diterpenoids from Salvia chamaedryoides. Journal of natural products 80 (2) (2017)
Marinella De Leo, Lorenzo Peruzzi, Carlotta Granchi, Tiziano Tuccinardi, Filippo Minutolo, Nunziatina De Tommasi, Alessandra Braca
Correction to Constituents of Polygala flavescens ssp. flavescens and Their Activity as Inhibitors of Human Lactate Dehydrogenase. Journal of natural products 80 (9) (2017)
Giulio Poli, Carlotta Granchi, Mohamed Aissaoui, Filippo Minutolo, Tiziano Tuccinardi
Three-Dimensional Analysis of the Interactions between hLDH5 and Its Inhibitors. Molecules (Basel, Switzerland) 22 (12) (2017)
Carlotta Granchi, Isabella Caligiuri, Eleonora Bertelli, Giulio Poli, Flavio Rizzolio, Marco Macchia, Adriano Martinelli, Filippo Minutolo, Tiziano Tuccinardi
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors. Journal of enzyme inhibition and medicinal chemistry 32 (1) (2017)
Carlotta Granchi, Isabella Caligiuri, Filippo Minutolo, Flavio Rizzolio, Tiziano Tuccinardi
A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017). Expert opinion on therapeutic patents 27 (12) (2017)
Marinella De Leo, Lorenzo Peruzzi, Carlotta Granchi, Tiziano Tuccinardi, Filippo Minutolo, Nunziatina De Tommasi, Alessandra Braca
Constituents of Polygala flavescens ssp. flavescens and Their Activity as Inhibitors of Human Lactate Dehydrogenase. Journal of natural products 80 (7) (2017)

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Tiziano Tuccinardi