Zhefan Stephen Chen

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 9

Top Venues

Nature communications

The Journal of neuroscience : the official journal of the Society for Neuroscience

The Journal of biological chemistry

Proceedings of the National Academy of Sciences of the United States of America

Chinese University of Hong Kong

Chinese University of Hong Kong (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Chinese University of Hong Kong Aug 01 2016

Hong Kong

Postdoctoral fellow :: School of Life Sciences

Education History

Chinese University of Hong Kong Aug 01 2012 - Jul 31 2016

Hong Kong

PHD :: School of Life Sciences

Publications

Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho-Yin Edwin Chan
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD. Nature communications 14 (1) (2023)
Zhefan Stephen Chen, Xiaoying Huang, Kevin Talbot, Ho-Yin Edwin Chan
A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3. Cell death & disease 12 (2) (2021)
Shaohong Peng, Pei Guo, Xiao Lin, Ying An, Kong Hung Sze, Matthew Ho Yan Lau, Zhefan Stephen Chen, Qianwen Wang, Wen Li, Jacquelyne Ka-Li Sun, Sum Yi Ma, Ting-Fung Chan, Kwok-Fai Lau, Jacky Chi Ki Ngo, Kin-Ming Kwan, Chun-Ho Wong, Sik Lok Lam, Steven C Zimmerman, Tiziano Tuccinardi, Zhong Zuo, Ho Yu Au-Yeung, Hei-Man Chow, Ho-Yin Edwin Chan
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
Zhefan Stephen Chen, Azaria Kam Yan Wong, Tat Cheung Cheng, Alex Chun Koon, Ho-Yin Edwin Chan
FipoQ/FBXO33, a Cullin-1-based ubiquitin ligase complex component modulates ubiquitination and solubility of polyglutamine disease protein. Journal of neurochemistry 149 (6) (2019)
Huiling Hong, Alex Chun Koon, Zhefan Stephen Chen, Yuming Wei, Ying An, Wen Li, Matthew Ho Yan Lau, Kwok-Fai Lau, Jacky Chi Ki Ngo, Chun-Ho Wong, Ho Yu Au-Yeung, Steven C Zimmerman, Ho-Yin Edwin Chan
AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models. The Journal of biological chemistry 294 (8) (2018)
Alex Chun Koon, Zhefan Stephen Chen, Shaohong Peng, Joyce Man See Fung, Xiaoman Zhang, Kayly M Lembke, Josh H K Chow, C Andrew Frank, Liwen Jiang, Kwok-Fai Lau, Ho-Yin Edwin Chan
Drosophila Exo70 Is Essential for Neurite Extension and Survival under Thermal Stress. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (37) (2018)

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Publication Activity (10 Years)

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Zhefan Stephen Chen