Hong-Yu Li

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 20

Top Topics

Tyrosine Kinase

Top Venues

Journal of medicinal chemistry

The Journal of organic chemistry

Organic letters

Medicinal research reviews

This page only lists publications with an associated author ORCID identifier.

Publications

Xiuqi Wang, Rosa Anna DeFilippis, Wei Yan, Neil P Shah, Hong-Yu Li
Overcoming Secondary Mutations of Type II Kinase Inhibitors. Journal of medicinal chemistry (2024)
Xiuqi Wang, Rosa Anna DeFilippis, Wei Yan, Neil P Shah, Hong-Yu Li
Overcoming Secondary Mutations of Type II Kinase Inhibitors. Journal of medicinal chemistry 67 (12) (2024)
Xiuqi Wang, Rosa Anna DeFilippis, Wei Yan, Neil P Shah, Hong-Yu Li
Overcoming Secondary Mutations of Type II Kinase Inhibitors. Journal of medicinal chemistry 67 (12) (2024)
Naga Rajiv Lakkaniga, Zhengyu Wang, Yao Xiao, Anupreet Kharbanda, Li Lan, Hong-Yu Li
Revisiting Aurora Kinase B: A promising therapeutic target for cancer therapy. Medicinal research reviews (2023)
Lingtian Zhang, Marialuisa Moccia, David C Briggs, Jaideep B Bharate, Naga Rajiv Lakkaniga, Phillip Knowles, Wei Yan, Phuc Tran, Anupreet Kharbanda, Xiuqi Wang, Yuet-Kin Leung, Brendan Frett, Massimo Santoro, Neil Q McDonald, Francesca Carlomagno, Hong-Yu Li
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose. Journal of medicinal chemistry 65 (2) (2022)
Jie Lei, Shi-Qiang Li, Ya-Fei Luo, Dian-Yong Tang, Cheng-He Zhou, Hong-Yu Li, Zhi-Gang Xu, Zhong-Zhu Chen
Zn(OTf) 2 -Promoted Isocyanide-Based Three-Component Reaction: Direct Access to 2-Oxazolines and β-Amino Amides. The Journal of organic chemistry 87 (17) (2022)
Wei Yan, Bo-Syong Pan, Jingwei Shao, Hui-Kuan Lin, Hong-Yu Li
Feasible Column Chromatography-Free, Multi-Gram Scale Synthetic Process of VH032 Amine, Which Could Enable Rapid PROTAC Library Construction. ACS omega 7 (30) (2022)
Yong Li, Jia Xu, Liu-Jun He, Ya-Fei Luo, Jiang-Ping Meng, Dian-Yong Tang, Hong-Yu Li, Zhong-Zhu Chen, Zhi-Gang Xu
Dieckmann Condensation of Ugi N -Acylamino Amide Product: Facile Access to Functionalized 2,2-Disubstituted Indolin-3-ones. The Journal of organic chemistry 87 (1) (2021)
Wei Yan, Naga Rajiv Lakkaniga, Francesca Carlomagno, Massimo Santoro, Neil Q McDonald, Fengping Lv, Naresh Gunaganti, Brendan Frett, Hong-Yu Li
Correction to Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application. Journal of medicinal chemistry 63 (17) (2020)
Marialuisa Moccia, Brendan Frett, Lingtian Zhang, Naga Rajiv Lakkaniga, David C Briggs, Rakhee Chauhan, Annalisa Brescia, Giorgia Federico, Wei Yan, Massimo Santoro, Neil Q McDonald, Hong-Yu Li, Francesca Carlomagno
Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology. Journal of medicinal chemistry 63 (9) (2020)
Di Zhang, Brandon E Burdette, Zhengyu Wang, Kumari Karn, Hong-Yu Li, Vern L Schramm, Peter C Tyler, Gary B Evans, Shanzhi Wang
Transition State Analogues Enhanced by Fragment-Based Structural Analysis: Bacterial Methylthioadenosine Nucleosidases. Biochemistry 59 (7) (2020)
Yafei Luo, Zheng Huang, Zhongzhu Chen, Zhi-Gang Xu, Jiangping Meng, Hong-Yu Li, Qingxi Meng, Dian-Yong Tang
Strategy Used to Control the Mechanism of Homogeneous Alkyne/Olefin Hydrogenation: AIMD Simulations and DFT Calculations. The Journal of organic chemistry 85 (18) (2020)
Jie Lei, Gui-Ting Song, Liu-Jun He, Ya-Fei Luo, Dian-Yong Tang, Hui-Kuan Lin, Brendan Frett, Hong-Yu Li, Zhong-Zhu Chen, Zhi-Gang Xu
One-pot construction of functionalized aziridines and maleimides via a novel pseudo-Knoevenagel cascade reaction. Chemical communications (Cambridge, England) 56 (14) (2020)
Chuan-Hua Qu, Gui-Ting Song, Dian-Yong Tang, Jing-Wei Shao, Hong-Yu Li, Zhi-Gang Xu, Zhong-Zhu Chen
Microwave-Assisted Copper Catalysis of α-Difluorinated gem-Diol toward Difluoroalkyl Radical for Hydrodifluoroalkylation of para-Quinone Methides. The Journal of organic chemistry 85 (19) (2020)
Chuan-Hua Qu, Gui-Ting Song, Jia Xu, Wei Yan, Cheng-He Zhou, Hong-Yu Li, Zhong-Zhu Chen, Zhi-Gang Xu
Merging Visible Light with Cross-Coupling: The Photochemical Direct C-H Difluoroalkylation of Imidazopyridines. Organic letters 21 (20) (2019)
Debasmita Saha, Anupreet Kharbanda, Wei Yan, Naga Rajiv Lakkaniga, Brendan Frett, Hong-Yu Li
The Exploration of Chirality for Improved Druggability within the Human Kinome. Journal of medicinal chemistry 63 (2) (2019)
Yong Li, Jiu-Hong Huang, Juan-Li Wang, Gui-Ting Song, Dian-Yong Tang, Fang Yao, Hui-Kuan Lin, Wei Yan, Hong-Yu Li, Zhi-Gang Xu, Zhong-Zhu Chen
Diversity-Oriented Synthesis of Imidazo-Dipyridines with Anticancer Activity via the Groebke-Blackburn-Bienaymé and TBAB-Mediated Cascade Reaction in One Pot. The Journal of organic chemistry 84 (19) (2019)
Zhi-Gang Xu, Shi-Qiang Li, Jiang-Ping Meng, Dian-Yong Tang, Liu-Jun He, Jie Lei, Hui-Kuan Lin, Hong-Yu Li, Zhong-Zhu Chen
Functionalized Spiroindolines with Anticancer Activity through a Metal-Free Post-Ugi Diastereoselective One-Pot Cascade Reaction. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (26) (2018)
Wei Yan, Naga Rajiv Lakkaniga, Francesca Carlomagno, Massimo Santoro, Neil Q McDonald, Fengping Lv, Naresh Gunaganti, Brendan Frett, Hong-Yu Li
Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application. Journal of medicinal chemistry 62 (4) (2018)
Zhong-Zhu Chen, Shi-Qiang Li, Ya-Jun Zhang, Dian-Yong Tang, Jiang-Ping Meng, Jie Lei, Hong-Yu Li, Zhi-Gang Xu
Synthesis of Pyridodiindoles with Anticancer Activity by a Three-Component Cascade Condensation. Organic letters 20 (24) (2018)