Peter C Tyler

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Venues

Biochemistry

ACS infectious diseases

ACS chemical biology

Nature communications

Victoria University of Wellington

Victoria University of Wellington (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Victoria University of Wellington

New Zealand

Professor :: Ferrier Research Institute

Education History

Victoria University of Wellington

New Zealand

PHD :: Chemistry

Publications

Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile -Induced Mortality. ACS infectious diseases 10 (3) (2024)
Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile -Induced Mortality. ACS infectious diseases 10 (3) (2024)
Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile -Induced Mortality. ACS infectious diseases (2024)
Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile -Induced Mortality. ACS infectious diseases (2024)
Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile -Induced Mortality. ACS infectious diseases 10 (3) (2024)
Morais Brown, Peter C Tyler, Vern L Schramm
Residence Times for Femtomolar and Picomolar Inhibitors of MTANs. Biochemistry (2023)
C H Andy Wong, Jonathan G Hubert, Kevin J Sparrow, Lawrence D Harris, Peter C Tyler, Margaret A Brimble
Expedient synthesis of imino-C-nucleoside fleximers featuring a one-pot procedure to prepare aryl triazoles. Organic & biomolecular chemistry (2023)
Kayla Glockzin, Kathleen M Meneely, Ryan Hughes, Sean W Maatouk, Grace E Piña, Kajitha Suthagar, Keith Clinch, Joshua N Buckler, Audrey L Lamb, Peter C Tyler, Thomas D Meek, Ardala Katzfuss
Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors. Biochemistry (2023)
Farah Lamiable-Oulaidi, Rajesh K Harijan, Karl J Shaffer, Douglas R Crump, Yan Sun, Quan Du, Shivali A Gulab, Ashna A Khan, Andreas Luxenburger, Anthony D Woolhouse, Simone Sidoli, Peter C Tyler, Vern L Schramm
Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1. Journal of medicinal chemistry 65 (7) (2022)
Kayla Glockzin, Demetrios Kostomiris, Yacoba V T Minnow, Kajitha Suthagar, Keith Clinch, Sinan Gai, Joshua N Buckler, Vern L Schramm, Peter C Tyler, Thomas D Meek, Ardala Katzfuss
Kinetic Characterization and Inhibition of Trypanosoma cruzi Hypoxanthine-Guanine Phosphoribosyltransferases. Biochemistry 61 (19) (2022)
Yacoba V T Minnow, Kajitha Suthagar, Keith Clinch, Rodrigo Gay Ducati, Agnidipta Ghosh, Joshua N Buckler, Rajesh K Harijan, Sean M Cahill, Peter C Tyler, Vern L Schramm
Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase. ACS chemical biology (2022)
Ashleigh S Paparella, Briana L Aboulache, Rajesh K Harijan, Kathryn S Potts, Peter C Tyler, Vern L Schramm
Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues. Nature communications 12 (1) (2021)
Daniel J Sheppard, Scott A Cameron, Peter C Tyler, Ralf Schwörer
Comparison of disaccharide donors for heparan sulfate synthesis: uronic acids vs. their pyranose equivalents. Organic & biomolecular chemistry 18 (25) (2021)
Mu Feng, Rajesh K Harijan, Lawrence D Harris, Peter C Tyler, Richard F G Fröhlich, Morais Brown, Vern L Schramm
Aminofutalosine Deaminase in the Menaquinone Pathway of Helicobacter pylori. Biochemistry 60 (24) (2021)
Rebecca Louise Miller, Scott E Guimond, Ralf Schwörer, Olga V Zubkova, Peter C Tyler, Yongmei Xu, Jian Liu, Pradeep Chopra, Geert-Jan Boons, Marko Grabarics, Christian Manz, Johanna Hofmann, Niclas G Karlsson, Jeremy E Turnbull, Weston B Struwe, Kevin Pagel
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides. Nature communications 11 (1) (2020)
Di Zhang, Brandon E Burdette, Zhengyu Wang, Kumari Karn, Hong-Yu Li, Vern L Schramm, Peter C Tyler, Gary B Evans, Shanzhi Wang
Transition State Analogues Enhanced by Fragment-Based Structural Analysis: Bacterial Methylthioadenosine Nucleosidases. Biochemistry 59 (7) (2020)
Rajesh K Harijan, Oskar Hoff, Rodrigo Gay Ducati, Ross S Firestone, Brett M Hirsch, Gary B Evans, Vern L Schramm, Peter C Tyler
Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase. Journal of medicinal chemistry 62 (7) (2019)
Gary B Evans, Vern L Schramm, Peter C Tyler
The transition to magic bullets - transition state analogue drug design. MedChemComm 9 (12) (2018)
Olga V Zubkova, Yassir A Ahmed, Scott E Guimond, Sophia-Louise Noble, John Holmes Miller, Raymond Alexander Alfred Smith, Victor Nurcombe, Peter C Tyler, Marina Weissmann, Israel Vlodavsky, Jeremy E Turnbull
Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy. ACS chemical biology 13 (12) (2018)
Rodrigo Gay Ducati, Rajesh K Harijan, Scott A Cameron, Peter C Tyler, Gary B Evans, Vern L Schramm
Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase. ACS chemical biology 13 (11) (2018)
Hilda A Namanja-Magliano, Gary B Evans, Rajesh K Harijan, Peter C Tyler, Vern L Schramm
Transition State Analogue Inhibitors of 5'-Deoxyadenosine/5'-Methylthioadenosine Nucleosidase from Mycobacterium tuberculosis. Biochemistry 56 (38) (2017)
Gary B Evans, Peter C Tyler, Vern L Schramm
Immucillins in Infectious Diseases. ACS infectious diseases 4 (2) (2017)
Gert-Jan Moggré, Myles B Poulin, Peter C Tyler, Vern L Schramm, Emily J Parker
Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase. ACS chemical biology 12 (10) (2017)
Truc V Pham, Andrew S Murkin, Margaret M Moynihan, Lawrence Harris, Peter C Tyler, Nishant Shetty, James C Sacchettini, Hsiao-Ling Huang, Thomas D Meek
Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America 114 (29) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Peter C Tyler